Modulation of bone turnover by alfacalcidol and/or alendronate does not prevent glucocorticoid-induced osteoporosis in growing minipigs

Journal of Bone and Mineral Metabolism

Volumn 23, Issue 5, 2005, Pages 341-350

  Akahoshi, Shojiro ^a   Sakai, Akinori ^a   Arita, Shinobu ^a   Ikeda, Satoshi ^a   Morishita, Yoshiomi ^b   Tsutsumi, Hideki ^c   Ito, Masako ^d   Shiraishi, Ayako ^b   Nakamura, Toshitaka ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^c Chugai Research Institute for Medical Science Inc   (Japan)

^d NAGASAKI UNIVERSITY   (Japan)

Author keywords

CT; Activation frequency; Bone formation; Bone resorption; Prednisolone

Indexed keywords

ALENDRONIC ACID; ALFACALCIDOL; BIOCHEMICAL MARKER; PREDNISOLONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MASS; BONE STRUCTURE; BONE TURNOVER; CONTROLLED STUDY; CORTICOSTEROID INDUCED OSTEOPOROSIS; DRUG EFFECT; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR SHAFT; LUMBAR DISK; MINIPIG; MORPHOMETRICS; NONHUMAN; OSSIFICATION; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL; TRABECULAR BONE;

ADJUVANTS, IMMUNOLOGIC; ALENDRONATE; ANIMALS; BODY WEIGHT; BONE AND BONES; BONE DENSITY; BONE REGENERATION; BONE RESORPTION; DENSITOMETRY, X-RAY; FEMUR; GLUCOCORTICOIDS; HYDROXYCHOLECALCIFEROLS; LUMBAR VERTEBRAE; OSTEOPOROSIS; PREDNISOLONE; SWINE; SWINE, MINIATURE; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 24044534169     PISSN: 09148779     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00774-005-0611-x     Document Type: Article

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