Effects of a synthetic vitamin D analog, ED-71, on bone dynamics and strength in cancellous and cortical bone in prednisolone-treated rats

Journal of Bone and Mineral Research

Volumn 11, Issue 3, 1996, Pages 325-336

  Tanaka, Yuzo ^a   Nakamura, Toshitaka ^a,c   Nishida, Satoshi ^a   Suzuki, Katsumi ^a   Takeda, Satoshi ^b   Sato, Katsuhiko ^b   Nishii, Yasuho ^b  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^c UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2BETA (3 HYDROXYPROPOXY)CALCITRIOL; CALCEIN; CALCIUM; PARATHYROID HORMONE; PREDNISOLONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE MASS; BONE METABOLISM; BONE MINERAL; BONE MINERALIZATION; CALCIUM ABSORPTION; CALCIUM URINE LEVEL; CANCELLOUS BONE; CONTROLLED STUDY; CORTICAL BONE; DOSE RESPONSE; FEMUR; MALE; NONHUMAN; OSSIFICATION; OSTEOLYSIS; PARATHYROID HORMONE RELEASE; RAT; TRABECULAR BONE;

EID: 0029960224     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbmr.5650110306     Document Type: Article

References (49)

1. Curtiss PH. Clark WS, Herndon CH 1954 Vertebral fractures resulting from prolonged cortisone and corticotropin therapy. JAMA 156:467-469.
2. Adinoff AD, Hollister JR 1983 Steroid-induced fractures and bone loss in patients with asthma. New Engl J Med 309:265-268.
3. Sambrook P, Birmingham J, Kempler S, Kelly P, Eberl S, Pocock N, Yeates M, Eisman J 1990 Corticoid effects on proximal femur bone loss. J Bone Miner Res 5:1211-1216.
4. Bressot C, Meunier PJ, Chapuy MC Lejeune E, Edouard C, Darby AJ 1979 Histomorphomtric profile, pathophysiology and reversibility of corticosteroid-induced osteoporosis. Metabol Bone Dis Rel Res 1:303-311.
5. Dietrich JW, Canalis EM, Maina DM, Raisz LG 1979 Effect of glucocorticoids on fetal rat bone collagen synthesis in vitro. Endocrinology 104:715-721.
6. Sambrook PM, Eisman JA. Champion GD, Pocock NA 1988 Sex hormone status and osteoporosis in postmenopausal women with rheumatoid arthritis. Arthritis Rhem 31:973-978.
7. Crilly R, Cawood M, Marshall DH. Nordin BEC 1978 Hormonal status in normal, osteoporotic and corticosteroid-treated postmenopausal women. J Roy Soc Med 71:733-736.
8. Sakakura M, Takebe K, Nakagawa S 1975 Inhibition of luteinizing hormone secretion induced by synthetic LRH by longterm treatment with glucocorticoids in human subjects. J Clin Endocrinol Metab 40:774-779.
9. Hsueh AJ, Erickson GF 1978 Glucocorticoid inhibition of FSH-induced estrogen production in cultured rat granulosa cells. Steroids 32:639-648.
10. Schaison G, Durand F, Mowszowicz I 1978 Effect of glueocorticoids on plasma testosterone in men. Acta Endocrinol (Copenhagen) 89:126-131.
11. MacAdams MR. White RH, Mowszowicz I 1978 Reduction of serum testosterone levels during chronic glucocorticoid therapy. Ann Intern Med 104:648-651.
12. Reid IR. Katz JM, Ibbertson HK, Gray DH 1986 The effects of hydrocortisone, parathyroid hormone and the bisphosphonate. APD, on bone resorption in neonatal mouse calvaria. Calcif Tissue Int 38:38-43.
13. Peck WA 1984 The effects of glucocoticoids on bone cell metabolism and function. Adv Exp Med 171:111-119.
14. Gennari C 1985 Glucocorticoids and bone. In: Peck WA (ed.) Bone and Mineral Research/3. Elsevier, Amsterdam, pp. 213-231.
15. Dempster DW, Alrot MA, Meunier PJ 1983 Mean wall thickness and formation periods of trabecular bone packets corticosteroid-induced osteoporosis. Calcif Tissue Int 35:410-417.
16. Dempster DW 1989 Bone histomorphometry in glucocorticoid-induced osteoporosis. J Bone Miner Res 4:137-141.
17. Hahn TJ, Halstead LR, Teitelbaum SL, Hahn BH 1979 Altered mineral metabolism in glucocorticoid-induced osteopenia. Effects of 25-hydroxyvitamin D administration. J Clin Invest 64:655-665.
18. Condon JR, Nassim JR, Dent CE, Hilb A, Stainthorpe EM 1978 Possible prevention and treatment of steroid-induced osteoporosis. Postgrad Med J 54:249-252.
19. Reid IR, Ibbertson HK 1986 Calcium supplements in the prevention of steroid-induced osteoporosis. Am J Clin Nutr 44:287-290.
20. Ringe JD. Welzel D 1987 Salmon calcitonin in the therapy of corticoid-induced osteoporosis. Eur J Clin Pharmacol 33:35-39.
21. Reid IR, Heap SW, King AR, Ibbertson HK 1988 Two-year follow-up of biphosphonate (APD) treatment in steroid osteoporosis (letter). Lancet 2:1144.
22. Grecu EO, Weinshelbaum A, Simmons R 1990 Effective therapy of glucocorticoid-induced osteoporosis with medroxyprogesterone acetate. Calcif Tissue Int 46:294-299.
23. Lukert BP, Johnson BE, Robinson RG 1992 Estrogen and progesterone replacement therapy reduces glucocorticoid-induced bone loss. J Bone Miner Res 7:1063-1068.
24. Faugere MC, Okamoto S. DeLuca HF, Malluche HH 1986 Calcitriol corrects bone loss induced by oophorectomy in rats. Am J Physiol 250:E35-E38.
25. Malluche HH, Matthews C, Faugere MC. Fanti P, Endres DB, Friedler RM 1986 1,25-Dihydroxyvitamin D maintains bone cell activity, and parathyroid hormone modulates bone cell number in dogs. Endocrinology 119:1298-1304.
26. 3 corrects bone loss but suppresses bone remodeling in ovariohysterectomized beagle dogs. Endocrinology 122:1998-2006.
27. 3 (ED-71), increases bone mass by stimulating the bone formation in normal and ovariectomized rats. Calcif Tissue Int 54:142-149.
28. 3 analogs and dexamethasone on the expression of osteocalcin gene in rat tibiae in vivo. Biochem Biophys Res Commun 189:1231-1235.
29. Gundberg CM, Hauschka PV, Lian JB, Gallop PM 1984 Osteocalcin, Isolation, characterization, and detection. Meth Enzymol 107:516-544.
30. Katsumata T, Nakamura T, Ohnishi H, Sakurama T 1995 Intermittent cyclical etidronate treatment maintains the mass, structure and the mechanical property of bone in ovariectomized rats. J Bone Miner Res 10:921-931.
31. Mosekilde L, Danielsen CC, Knudsen UB 1993 The effect of aging and ovariectomy on the vertebral bone mass and biomechanical properties of mature rats. Bone 14:1-6.
32. Turner RT 1994 Cancellous bone turnover in growing rats: Time-dependent changes in association between calcein label and osteoblasts. J Bone Miner Res 9:1419-1424.
33. Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Maccuche H, Meunier PJ, Ott SM, Recker RR1987 Bone histomorphometry: Standardization of nomenclature, symbols, and units. Report of ASBMR Histomorphometry Committee. J Bone Miner Res 2:595-610.
34. Frost HM 1983 Bone histomorphometry: Analysis of trabecular bone dynamics. In Recker RR (ed.) Bone Histomorphometry: Techniques and Interpretations. CRC Press, Boca Raton, Florida, pp. 109-131.
35. 3: An effective prophylactic treatment for glucocorticoid osteopenia in rats. Calcif Tissue Int 35:107-110.
36. Swissa-Sivan A, Statter M, Brooks GA, Azevedo J, Viguie C, Azoury R, Greenfield C, Oman S, Leichter I, Zinker BA, Menczel J 1992 Effect of swimming on prednisoloae-induced osteoporosis in elderly rats. J Bone Miner Res 7:161-169.
37. Baylink DJ 1983 Glucocorticoid-induced osteoporosis. New Engl J Med 309:306-308.
38. Avioli LV 1984 Effects of chronic corticosteroid therapy on mineral metabolism and calcium absorption. Adv Exp Med Biol 171:81-89.
39. Gennari C, Imbimbo B, Montagnani M, Bernini M, Nardi P, Avioli LV 1984 Effects of prednisone and deflazacort on mineral metabolism and parathyroid hormone activity in humans. Calcif Tissue Int 36:245-252.
40. Gallagher JC, Aaron J, Horsman A, Wilkinson R, Nordin BEC 1973 Corticosteroid osteoporosis. Clin Endocrinol Metabol 2:355-368.
41. Lund B, Storm TL, Lund B, Melsen F, Mosekilde L, Andersen RB, Egmose C, Sorensen OH 1985 Bone mineral loss, bone histomorphometry and vitamin D metabolism in patients with rheumatoid arthritis on long-term glucocorticoid treatment. Clin Rheumatol 4:143-149.
42. Aaron JE, Francis RM, Peacock M, Makins NB 1989 Contrasting microanatomy of idiopathic and corticosteroid-induced osteoporosis. Clin Ortho 243:294-305.
43. Eriksen EF 1986 Normal and pathological remodeling of human trabecular bone: Three dimensional reconstruction of the remodeling sequence in normals and in metabolic bone disease. Endocrinol Rev 7:379-408.
44. 3 on osteopenia induced by prednisolone in adult rats. Calcif Tissue Int 34:253-257.
45. 3. Clin Ortho 181:264-268.
46. 3 in normal rats and in rats treated with prednisolone. Acta Endocrinol 106:564-568.
47. 3 modulates glucocorticoid-induced alteration in serum bone gla protein and bone histomorphometry. Endocrinology 120:531-536.
48. 3 (ED-71), on bone metabolism in organ culture. Bone 14:47-51.
49. 3 derivative, on calcium metabolism. Biochem Biophys Res Commun 163:1444-1449.