Telomerase reverse transcriptase mRNA expression in peripheral lymphocytes of patients with chronic HBV and HCV infections

Journal of Viral Hepatitis

Volumn 12, Issue 5, 2005, Pages 488-493

  Satra, M ^a   Dalekos, G N ^a   Kollia, P ^a   Vamvakopoulos, N ^a   Tsezou, Aspasia ^a  

^a UNIVERSITY OF THESSALY   (Greece)

Author keywords

Hepatitis B; Hepatitis C; Hepatocellular carcinoma; Telomerase; Telomeres

Indexed keywords

MESSENGER RNA; TELOMERASE REVERSE TRANSCRIPTASE;

ADULT; ARTICLE; CELL AGING; CHRONIC HEPATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; HEPATITIS B; HEPATITIS B VIRUS; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IMMUNOPATHOGENESIS; LIVER CELL CARCINOMA; MALE; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; TELOMERE; UPREGULATION; VIRUS REPLICATION;

ADULT; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATITIS B, CHRONIC; HEPATITIS C, CHRONIC; HUMANS; LEUKOCYTES; LIVER NEOPLASMS; MALE; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TELOMERASE;

EID: 24044528538     PISSN: 13520504     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2893.2005.00550.x     Document Type: Article

References (37)

1. Wright WE, Tesmer VM, Huffman KE, Levene SD, Shay JW. Normal human chromosomes have long G-rich telomeric overhangs at one end. Genes Dev 1997; 11: 2801-2809.
2. Blackburn EH. Switching and signaling at the telomere. Cell 2001; 106: 661-673.
3. Cong YS, Wright WE, Shay JW. Human telomerase and its regulation. Micr Mol Biol Rev 2002; 66: 407-425.
4. Erlitzki R, Minuk GY. Telomeres, telomerase and HCC: the long and the short of it. J Hepatol 1999; 31: 939-945.
5. Meyerson M. Role of telomerase in normal and cancer cells. J Clin Oncol 2000; 18: 2626-2634.
6. De Lange T, Shiue I, Myers RM et al. Structure and variability of human chromosome ends. Mol Cell Biol 1990; 10: 518-527.
7. Linddsey J, McGill NI, Lindsey LA, Green DK, Cooke HJ. In vivo loss of telomeric repeats with age in humans. Mutat Res 1991; 256: 45-48.
8. Harley CB, Vaziri H, Counter C, Allsopp RC. The telomere hypothesis of cellular aging. Exp Gerontol 1992; 27: 375-382.
9. Holt SE, Shay JW. Role of telomerase in cell proliferation and cancer. J Cell Physiol 1999; 180: 10-11.
10. Feng J, Funk IW, Wang SS. The RNA component of human telomerase. Science 1995; 269: 1236-1241.
11. Harrington IW, Zhou W, McPhail T et al. Human telomerase contains evolutionary conserved catalytic and structural subunits. Genes De 1997; 11: 3109-3115.
12. Avilion AA, Piatyszek MA, Gupta J, Shay JW, Bacchetti S, Greider CW. Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues. Cancer Res 1996; 56: 645-650.
13. Yi X, Tesmer VM, Savre-Train I, Shay JW, Wright WE. Both transcriptional and posttranscriptional mechanisms regulate human template RNA levels. Mol Exp Biol 1999; 19: 3989-3997.
14. Stanta G, Bonin S, Niccolini B, Raccanelli A, Bavalle F. Catalytic subunit of telomerase expression is related to RNA component expression. FEBS Lett 1999; 460: 285-288.
15. Kim NW, Piatyszek MA, Prowse KR et al. Specific association of human telomerase activity with immortal cells and cancer. Science 1994; 266: 2011-2015.
16. Harle C, Boukamp P. Telomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal carcinoma-derived skin keratinocytes. PNAS 1996; 93: 6476-6481.
17. Weng NP, Levine BL, June CH, Hodes RJ. Regulated expression of telomerase activity in human T lymphocyte development and activation. J Exp Med 1996; 183: 2471-2479.
18. Yamada O, Motoji T, Mizoggucchi H. Up regulation of telomerase activity in human lymphocytes. Biochem Biophys Acta 1996; 1319: 260-266.
19. Weny DP, Levine BL, June, C, Holes RJ. Human naive and memory T lymphocytes differ in telomeric length and replicative potential. PNAS 1995; 92: 11091-11094.
20. Weng N, Palmer I, Levine BL, Lane CH, June C, Hodes RJ. Tales of tails: regulation of telomere length and telomerase activity during lymphocyte development, differentiation, activation and aging. Immunol Rev 1997; 160: 43-54.
21. Fan X, Huang Y, Tang F, Yi H. Telomerase activity of peripheral blood lymphocytes in patients with chronic hepatitis hepatitis B. Immunol Let 2000; 73: 7-11.
22. Dalekos GN, Christodoulou D, Kistis KG, Zervou EK, Hatzis J, Tsianos EV. A prospective evaluation of dermatologic side effects during alpha-interferon therapy for chronic viral hepatitis. Eur J Gastroenterol Hepatol 1998; 10: 933-939.
23. Dalekos GN, Achenbach K, Christodoulou D et al. Idiopathic dilated cardiomyopathy: lack of association with hepatitis C virus infection. Heart 1998; 80: 270-275.
24. The EASL Jury. Consensus statement (Short version). EASL International Consensus Conference on Hepatitis B, 13-14 September 2002, Geneva, Switzerland. J Hepatol 2003; 38: 533-540.
25. Meyerson M, Counter CM, Eaton EN et al. hEST2, the putative human telomerase catalytic subunit gene is upregulated in tumor cells and during immortalization. Cell 1997; 90: 785-790.
26. Wada E, Hisatomi H, Moritoyo T, Kanamaru T, Hikiji K. Genetic diagnostic test of hepatocellular carcinoma by telomerase catalytic subunit mRNA. Oncol Rep 1998; 5: 1407-1412.
27. Hisatomi H, Nagao K, Kanamaru T, Endo H, Tomimatsu M, Hikiji K. Levels of telomerase catalytic subunit mRNA as a predictor of potential malignancy. Int J Oncol 1999; 14: 727-732.
28. Satyanarayana A, Wiemann Su, Buer J et al. Telomeres shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells. EMBO J 2003; 22: 4003-4013.
29. De Mitri MS, Poussin K, Baccarini P et al. HCV-associated liver cancer without cirrhosis. Lancet 1995; 345: 413-415.
30. El-Refaie A, Savage K, Bhattacharya S et al. HCV-associated hepatocellular carcinoma without cirrhosis. J Hepatol 1996; 24: 277-285.
31. Tatsuma T, Goto S, Kitano S, Lin YC, Lee CM, Chen CL. Telomerase activity in peripheral blood for diagnosis of hepatoma. J Gastroenteol Hepatol 2000; 15: 1064-1070.
32. Kojima H, Kaita KDE, Xu Z et al. The absence of up-regulation of telomerase activity after partial hepatectomy in hepatitis B virus X gene transgenic mice. J Hepatol 2003; 39: 262-268.
33. Liu K, Schoonmaker MM, Levine BL, June CH, Hodes RJ, Weng NP. Constitutive and regulated expression of telomerase reverse transcriptase (hTERT) in human lymphocytes. PNAS 1999; 96: 5147-5152.
34. Cohen J. Selling the immune system short. Science 1996; 273: 30-31.
35. Pawelwec G, Solana R. Immunosenescence. Trends Immunol 1997; 18: 514-516.
36. Bryan TM, Reddel RR. Telomere dynamics and telomerase activity in in vitro immortalized human cells. Eur J Cancer 1997; 33(5): 767-773.
37. Nakamura K, Yuh K, Sugyo S, Shijo H, Kimura N, Okumura M. Apoptosis observed in peripheral T-lymphocytes from patients with chronic hepatitis B. Gastroenterology 1996; 111: 156-164.