Effect of IL-10 on the expression of HSC growth factors in hepatic fibrosis rat

World Journal of Gastroenterology

Volumn 11, Issue 31, 2005, Pages 4788-4793

  Shi, Mei Na ^a   Zheng, Wei Da ^a   Zhang, Li Juan ^a   Chen, Zhi Xin ^a   Wang, Xiao Zhong ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Epidermal growth factor; Hepatic fibrosis; Hepatic stellate cells; Hepatocyte growth factor; Interleukin 10; Platelet derived growth factor; Transforming growth factor 1

Indexed keywords

EPIDERMAL GROWTH FACTOR; GELATINASE A; GROWTH FACTOR; INTERLEUKIN 10; IOHEXOL; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR; PRONASE; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL ISOLATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; DISEASE MODEL; DRUG MECHANISM; IMMUNOCYTOCHEMISTRY; LIVER FIBROSIS; MALE; NONHUMAN; PORTAL VEIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RANDOMIZATION; RAT; RAT STRAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STELLATE CELL; TREATMENT OUTCOME; VEIN CATHETERIZATION;

EID: 24044505322     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i31.4788     Document Type: Article

References (29)

1. Bataller R, Bremmer DA. Hepatic stellate cells as a target for the treatment of liver fibrosis. Semin Liver Dis 2001; 21: 437-451
2. Wang FS, Wu ZZ. Current situation in studies of gene therapy of liver cirrhosis and liver fibrosis. Shijie Huaren Xiaohua Zazhi 2000; 8: 371-373
3. Xiang DD, Wei YL, Li QF. Molecular mechanism of transforming growth factor b1 on Ito cell. Shijie Huanren Xiaohua Zazhi 1999; 7: 980-981
4. Morrow JD, Awad JA, Kato T, Takahashi K, Badr KF, Robert LJ 2nd, Burk KF. Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation. J Clin Invest 1992; 90: 2502-2507
5. Nelson DR, Lauwers GY, Lau JY, Davis GL. Interleukin 10 treatment reduces fibrosis in patients with chronic hepatitis C: a pilot trial of interferon nonresponders. Gastroenterology 2000; 118: 655-660
6. Zheng WD, Wang XZ, Zhang LJ, Shi MN. A simple and reliable method of isolating rat hepatic stellate cells. Fujian Yikedaxue Xuebao 2002; 38: 71-73
7. Schuppan D, Strobel D, Hahn EG. Hepatic fibrosis therapeutic strategies. Digestion 1998; 59: 385-390
8. Pinzane M, Marra F, Carloni V. Signal transduction in hepatic stellate cells. Liver 1998; 18: 2-13
9. Gressner AM. The cell biology of liver fibrogenesis: an imbalance of proliferation, growth arrest and apoptosis of myofibroblasts. Cell Tissue Res 1998; 292: 447-452
10. Ledeboer A, Breve JJ, Poole S, Tilders FJ, Van Dam AM. Interleukin-10, interleukin-4, and transforming growth factor-beta differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in co-cultures of rat astroglial and microglial cells. Glia 2000; 30: 134-142
11. Marques CP, Hu S, Sheng W, Cheeran MC, Cox D, Lokensgard JR. Interleukin-10 attenuates production of HSV-induced inflammatory mediators by human microglia. Glia 2004; 47: 358-366
12. Mitchell MD, Simpson KL, Keelan JA. Paradoxical proinflammatory actions of interleukin-10 in human amnion: potential roles in term and preterm labour. J Clin Endocrinol Metab 2004; 89: 4149-4152
13. Xu XB, He ZP, Liang ZQ, Leng XS. Obstruction of TGF-b1 signal transduction by anti-Smad4 gene can therapy experimental liver fibrosis in the rat[Article in Chinese. Zhonghua Ganzangbing Zazhi 2004; 12: 263-266
14. Wu XR, Lv MH, Wang Q, Shi SS, Guo WD. The plasma levels of transforming growth factor beta1 and the protein expressions of alpha-SMA, urokinase plasminogen activator and plasminogen activator inhibitor-1 in liver of patients with different grades of hepatic fibrosis. Zhonghua Ganzangbing Zazhi 2004; 12: 400-402
15. Ma C, Chegini N. Regulation of matrix metalloproteinases (MMPs) and their tissue inhibitors in human myometrial smooth muscle cells by TGF-beta 1. Mol Hum Repod 1999; 5: 950-954
16. Knittel T, Mehde M, Kobold D, Saile B, Dinter C, Ramadori G. Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-parenchymal cells of rat liver]: regulation by TNF-alpha and TGF-beta1. J Hepatol 1999; 30: 48-60
17. Komuves LG, Feren A, Jones AL, Fodor E. Expression of epidermal growth factor and its receptor in cirrhotic lever disease. J Histochem Cytochem 2000; 48: 821-830
18. Liu X, Zhang J, Zhang Y. Effects of platelet-derived growth factor on the proliferation of hepatic stellate cells and their expression of genes of collagens and platelet-derived growth factor. Zhonghua Binglixue Zazhi 2000; 29: 27-29
19. Yang C, Zeisberg M, Mosterman B, Sudhakar A, Yerramalla U, Holthaus K, Xu L, Eng F, Afdhal N, Kalluri R. Liver fibrosis: insights into migration of hepatic stellate cells in reponse to extracellular matrix and growth factors. Gastroenterology 2003; 12: 147-159
20. Mars WM, Zarnegar R, Michalopoulos GK. Activation of hepatocyte growth factor by the plasminogen activators uPA and tPA. Am J Pathol 1993; 143: 949-958
21. Kosai K, Matsumoto K, Nagata S, Tsujimoto Y, Nakamura T. Abrogation of Fas-induced fulminant hepatic failure in mice by hepatocyte growth factor. Biochem Biophys Res Commun 1998; 244: 683-690
22. Sato M, Kakubari M, Kawamura M, Sugimoto J, Matsumoto K, Ishii T. The decrease in total collagen fibers in the liver by hepatocyte growth factor after formation of cirrhosis induced by thioacetamide. Biochem Pharmacol 2000; 59: 681-690
23. Ueki T, Kaneda Y, Tsutsui H, Nakanishi K, Sawa Y, Morishita R, Matsumoto K, Nakamura T, Takahashi H, Okamoto E, Fujimoto J. Hepatocyte growth factor gene therapy of liver cirrhosis in rats. Nat Med 1999; 5: 226-230
24. Goda K, Fujisawa M, Shirakawa T, Dobashi M, Shiota G, Zhang ZJ, Gotoh A, Kamidono S. Adenoviral-mediated HGF expression inhibits germ cell apoptosis in rats with cryptorchidism. J Gene Med 2004; 6: 869-876
25. Okada M, Sugita K, Inukai T, Goi K, Kagami K, Kawasaki K, Nakazawa S. Hepatocyte growth factor protects small airway epithelial cells from apoptosis induced by tumor necrosis factor-{alpha} or oxidative stress. Pediatr Res 2004; 56: 336-344
26. Liu Y. Hepatocyte growth factor in kidney fibrosis: therapeutic potential and mechanisms of action. Am J Physiol Renal Physiol 2004; 287: F7-16
27. Kuter DJ. Future directions with platelet growth factors. Semin Hematol 2000; 37(2 Suppl 4): 41-49
28. Pinzani M. Pdgf and signal transduction in hepatic stellate cells. Front Biosci 2002; 7: D1720-1726
29. Yuan N, Wang P, Wang Z. Expression and significance of platelet derived growth factor and its receptor in liver tissues of patients with liver fibrosis. Zhonghua Ganzangbing Zazhi 2002; 10: 58-60