Ectoine alters subcellular localization of inclusions and reduces apoptotic cell death induced by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch

Neurobiology of Disease

Volumn 20, Issue 1, 2005, Pages 170-178

  Furusho, Kentaro ^a   Yoshizawa, Toshihiro ^a   Shoji, Shinichi ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Apoptotic cell death; Ataxin 3; Compatible solute; Ectoine; Inclusion; Machado Joseph disease; Polyglutamine

Indexed keywords

BETAINE; ECTOINE; GENE PRODUCT; HYDROECTOINE; POLYGLUTAMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BACTERIUM; CELL AGGREGATION; CELL CULTURE; CELL INCLUSION; CELL LINE; CELL NUCLEUS INCLUSION BODY; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; FREQUENCY ANALYSIS; IMMUNOBLOTTING; MACHADO JOSEPH DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

AMINO ACIDS, DIAMINO; ANIMALS; APOPTOSIS; BETAINE; CELL LINE, TUMOR; CELL NUCLEUS; CYTOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GASTROINTESTINAL AGENTS; INCLUSION BODIES; MACHADO-JOSEPH DISEASE; MICE; NERVE DEGENERATION; NERVE TISSUE PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; NUCLEAR PROTEINS; PEPTIDES; PROTEIN FOLDING; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 24044487179     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.02.011     Document Type: Article

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