Catalytic mechanism of hamster arylamine N-acetyltransferase 2

Biochemistry

Volumn 44, Issue 33, 2005, Pages 11295-11306

  Wang, Haiqing ^a   Liu, Li ^a   Hanna, Patrick E ^a   Wagner, Carston R ^a,b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; AMINES; CARCINOGENS; DRUG DOSAGE; ISOTOPES; METABOLISM; PH EFFECTS; PHYSIOLOGY;

BIOACTIVATION; N-ACETYLTRANSFERASES (NAT); SOLVENT KINETIC ISOTOPE EFFECT (SKIE); XENOBIOTICS;

ENZYMES;

4 NITROPHENYL ACETATE; ACETIC ACID DERIVATIVE; ACETYL COENZYME A; ACYLTRANSFERASE; AROMATIC AMINE; ARYLAMINE N ACETYLTRANSFERASE 2; ASPARAGINE; ASPARTIC ACID; CARCINOGEN; CYSTEINE; GLUTAMINE; HISTIDINE; HYDRAZIDE; HYDRAZINE DERIVATIVE; IMIDAZOLE; IMIDAZOLE DERIVATIVE; NITRO DERIVATIVE; SOLVENT; THIOL DERIVATIVE; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ACETYLATION; ACID BASE BALANCE; ARTICLE; CONTROLLED STUDY; DEACETYLATION; DRUG ACTIVATION; DRUG METABOLISM; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; HAMSTER; HYDROLYSIS; MUTANT; NONHUMAN; PH; PKA; PRIORITY JOURNAL; REACTION ANALYSIS; STEADY STATE; XENOBIOTIC METABOLISM;

ACETYL COENZYME A; AMINES; AMINO ACID SUBSTITUTION; ANIMALS; ARYLAMINE N-ACETYLTRANSFERASE; CARCINOGENS; CATALYSIS; CRICETINAE; HYDRAZINES; HYDROGEN-ION CONCENTRATION; KINETICS; NITROPHENOLS; PROTEIN BINDING; XENOBIOTICS;

CRICETINAE;

EID: 23944498571     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi047564q     Document Type: Article

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