3D model of human arylamine N-acetyltransferase 2: Structural basis of the slow acetylator phenotype of the R64Q variant and analysis of the active-site loop

Biochemical and Biophysical Research Communications

Volumn 291, Issue 1, 2002, Pages 116-123

  Rodrigues Lima, Fernando ^a   Dupret, Jean Marie ^b  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Homology modeling; Loop; NAT2; Polymorphism; Structure function

Indexed keywords

ARGININE; ARYLAMINE ACETYLTRANSFERASE; GLUTAMINE;

ACETYLATION; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SUBSTRATE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; MOLECULAR MODEL; MOLECULAR RECOGNITION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; SEQUENCE HOMOLOGY;

SALMONELLA TYPHIMURIUM;

EID: 0036085411     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2002.6414     Document Type: Article

References (28)

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