Identification of amino acids imparting acceptor substrate selectivity to human arylamine acetyltransferases NAT1 and NAT2

Biochemical Journal

Volumn 348, Issue 1, 2000, Pages 159-166

  Goodfellow, Geoffrey H ^a   Dupret, Jean Marie ^b   Grant, Denis M ^a  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b HÔPITAL ROBERT DEBRÉ   (France)

Author keywords

Enzyme kinetics; Site directed mutagenesis; Structure function

Indexed keywords

AMINOSALICYLIC ACID; ARGININE; ARYLAMINE ACETYLTRANSFERASE; CYSTEINE; PHENYLALANINE; SULFADIMIDINE;

ACETYLATION; AMINO ACID SEQUENCE; ARTICLE; CHIMERA; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME SUBSTRATE COMPLEX; GENETIC CONSERVATION; HUMAN; MICHAELIS CONSTANT; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; AMINO ACIDS; ARYLAMINE N-ACETYLTRANSFERASE; BASE SEQUENCE; ENZYME STABILITY; HUMANS; IMMUNOASSAY; ISOENZYMES; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

CHIMAERA;

EID: 0034658314     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3480159     Document Type: Article

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