The effect of taurine or betaine pretreatment on hepatotoxicity and prooxidant status induced by lipopolysaccharide treatment in the liver of rats

European Journal of Gastroenterology and Hepatology

Volumn 17, Issue 9, 2005, Pages 917-921

  Balkan, Jale ^a   Parildar, Fatma Hande ^a   Doǧru Abbasoǧlu, Semra ^a   Aykaç Toker, Gülçin ^a   Uysal, Müjdat ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Betaine; Lipopolysaccharide; Liver; Oxidative stress; Rat; Taurine

Indexed keywords

ALKADIENE; ALPHA TOCOPHEROL; AMINOTRANSFERASE; ANTIOXIDANT; ASCORBIC ACID; BETAINE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LIPOPOLYSACCHARIDE; MALONALDEHYDE; SUPEROXIDE DISMUTASE; TAURINE;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; KUPFFER CELL; LIVER PROTECTION; LIVER TOXICITY; MALE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIOXIDANTS; BETAINE; LIPOPOLYSACCHARIDES; LIVER DISEASES; MALE; MALONDIALDEHYDE; OXIDATIVE STRESS; RATS; RATS, WISTAR; TAURINE; TRANSAMINASES;

EID: 23944457613     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-200509000-00006     Document Type: Article

References (38)

1. Portoles MT, Ainaga MJ, Pagani R. The induction of lipid peroxidation by E. coli lipopolysaccharide on rat hepatocytes as an important factor in the etiology of endotoxic liver damage. Biochim Biophys Acta 1993; 1158: 287-292.
2. Sewerynek E, Melchiorri D, Reiter RJ, Ortiz GG, Lewinski A. Lipopolysaccharide-induced hepatotoxicity is inhibited by the antioxidant melatonin. Eur J Pharmacol 1995; 293:327-334.
3. Mutlu-Türkoǧlu Ü, Öztezcan S, Tamer-Toptani S, Uysal M, Aykaç-Toker G. The effect of N-acetyl-cysteine and N-ω-nitro-L-arginine methyl ester treatment on lipopolysaccharide-induced oxidative stress in lung of rats. Biochem Arch 1998; 14:139-146.
4. Uedono Y, Takeyama N, Yamagami K, Tanaka T. Lipopolysaccharide-mediated hepatic glutathione depletion and progressive mitochondrial damage in mice: protective effect of glutathione monoethyl ester. J Surg Res 1997; 70:49-54.
5. Cadenas S, Rojas C, Barja G. Endotoxin increases oxidative injury to proteins in guinea pig liver: protection by dietary vitamin C. Pharmacol Toxicol 1998; 82:11-18.
6. Ben-Shaul V, Lomnitski L, Nyska A, Carbonatto M, Peano S, Zurovsky Y, et al. Effect of natural antioxidants and apocynin on LPS-induced endotoxemia in rabbit. Human Exp Toxicol 2000; 19:604-614.
7. Cadenas S, Cadenas AM. Fighting the stranger-antioxidant protection against endotoxin toxicity. Toxicology 2002; 180:45-63.
8. Suntres ZE. Prophylaxis against lipopolysaccharide-induced liver injuries by lipoic acid in rats. Pharmacol Res 2003; 48:585-591.
9. Victor VM, Rocha M, De la Fuente M. Regulation of macrophage function by the antioxidant N-acetylcysteine in mouse-oxidative stress by endotoxin. Int Immunopharmacol 2003; 3:97-106.
10. Su GL. Lipopolysaccharides in liver injury: molecular mechanisms of Kupffer cell activation. Am J Gastrointest Liver Physiol 2002; 283:G256-G265.
11. Yee SB, Ganey PE, Roth RA. The roles of Kupffer cells and TNF-α in monocrotaline and bacterial lipopolysaccharide-induced liver injury. Toxicol Sci 2002; 71:124-132.
12. Brown AP, Harkema JR, Schultze AE, Roth RA, Ganey PE. Gadolinium chloride pretreatment protects against hepatic injury but predisposes the lung to alveolitis after lipopolysaccharide administration. Shock 1997; 7:186-192.
13. Doǧru-Abbasoǧlu S, Kanbaǧli Ö, Balkan J, Çevikbaş U, Aykaç-Toker G, Uysal M. The protective effect of taurine against thioacetamide hepatotoxicity of rats. Human Exp Toxicol 2001; 20:23-27.
14. Waters E, Wang JH, Redmond HP, Wu Q, Kay E, Hayes DB. Role of taurine in preventing acetaminophen-induced hepatic injury in the rat. Am J Physiol Gastrointest Liver Physiol 2001; 280:G1272-G1279.
15. Balkan J, Kanbaǧli Ö, Aykaç-Toker G, Uysal M. Taurine treatment reduces hepatic lipids and oxidative stress in chronically ethanol treated rats. Biol Pharm Bull 2002; 25:1231-1233.
16. Erman F, Balkan J, Cevikbaş U, Koçak-Toker N, Uysal M. Betaine or taurine administration prevents fibrosis and lipid peroxidation induced by rat liver by ethanol plus carbon tetrachloride intoxication. Amino Acids 2004; 27: 199-205.
17. Barak AJ, Beckenhauer HC, Tuma DJ. Betaine, ethanol, and the liver: a review. Alcohol 1996; 13:395-398.
18. Junnila M, Rahko T, Sukura A, Lindberg LA. Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats. Vet Human Toxicol 1998; 40:263-266.
19. Balkan J, Öztezcan S, Kücük M, Çevikbaş U, Koçak-Toker N, Uysal M. The effect of betaine treatment on triglyceride levels and oxidative stress in the liver of ethanol-treated guinea pigs. Exp Toxic Pathol 2004; 55:505-509.
20. Redmond HP, Wang JH, Hayes DB. Taurine attenuates nitric oxide- and reactive oxygen intermediate-dependent hepatocyte injury. Arch Surg 1996; 131:1280-1288.
21. Zhang F, Warskulat U, Wettstein M, Haussinger D. Identification of betaine as an osmolyte in rat liver macrophages (Kupffer cells). Gastroenterology 1996; 110:1543-1552.
22. Warskulat U, Zhang F, Haussinger D. Taurine is an osmolyte in rat liver macrophages (Kupffer cells). J Hepatol 1997; 26:1340-1347.
23. Kim SK, Kim YC. Attenuation of bacterial lipopolysaccharide-induced hepatotoxicity by betaine or taurine in rats. Food Chem Toxicol 2002; 40:545-549.
24. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxidation in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95:351-358.
25. Buege JA, Aust JD. Microsomal lipid peroxidation. Method Enzymol 1978; 52:302-310.
26. Beutler E, Duron O, Kelly BM. Improved method for the determination of blood glutathione. J Lab Clin Med 1979; 61:882-888.
27. Desai DI. Vitamin E analysis methods for animal tissues. Method Enzymol 1984; 105:138-147.
28. Omaye ST, Turnbull JD, Sauberlich HE. Selected methods for the determination of ascorbic acid in animal cells, tissues and fluids. Method Enzymol 1979; 62:3-8.
29. Mylorie AA, Collins H, Umbles C, Kyle J. Erythrocyte superoxide dismutase activity and other parameters of copper status in rats ingesting lead acetate. Toxicol Appl Pharmacol 1986; 82:512-520.
30. Lawrence RA, Burk RF. Glutathione peroxidase activity in selenium-deficient rat liver. Biochem Biophys Res Commun 1976; 71:952-958.
31. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, et al. Measurement of protein using bicinchoninic acid. Anal Biochem 1985; 150:76-85.
32. Hansen SH. The role of taurine in diabetes and the development of diabetic complications. Diabetes Metab Res Rev 2001; 17:330-346.
33. Lieber CS. S-adenosyl-L-methionine: its role in the treatment of liver disorders. Am J Clin Nutr 2002; 76 (suppl):1183S-1187S.
34. Mutlu-Türkoǧlu Ü, Tamer-Toptani S, Öztezcan S, Uysal M, Toker G. The effects of N-acetylcysteine treatment and nitric oxide synthase inhibition on oxidative stress induced by E. coli endotoxin. Biochem Arch 1998; 14:33-41.
35. Yoshikawa T, Takano H, Takahashi S, Ichikawa H, Kondo M. Changes in tissue antioxidant enzyme activities and lipid peroxides in endotoxin-induced multiple organ failure. Circulatory Shock 1994; 42:53-58.
36. Portoles MT, Catala M, Anton A, Pagani R. Hepatic response to the oxidative stress induced by E. coli endotoxin: glutathione as an index of the acute phase during the endotoxic shock. Mol Cell Biochem 1996; 159: 115-121.
37. Spolarics Z. Endotoxin stimulates gene expression of ROS-eliminating pathways in rat hepatic endothelial and Kupffer cells. Am J Physiol 1996; 270:G660-G666.
38. Ben-Shaul V, Sofer Y, Bergman M, Zurovsky Y, Grossman S. Lipopolysaccharide-induced oxidative stress in the liver: comparison between rat and rabbit. Shock 1999; 12:288-293.