Gadolinium chloride pretreatment protects against hepatic injury but predisposes the lungs to alveolitis after lipopolysaccharide administration

Shock

Volumn 7, Issue 3, 1997, Pages 186-192

  Brown, Alan P ^a   Harkema, Jack R ^a,b   Eric Schultze, A ^c   Roth, Robert A ^a,b   Ganey, Patricia E ^a,b  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c UNIVERSITY OF TENNESSEE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM; GADOLINIUM CHLORIDE; LIPOPOLYSACCHARIDE;

ANIMAL; ARTICLE; CHEMICALLY INDUCED DISORDER; FEMALE; IMMUNOLOGY; KUPFFER CELL; LIVER; LIVER DISEASE; LUNG DISEASE; LUNG FIBROSIS; NEUTROPHIL; PATHOPHYSIOLOGY; PHAGOCYTOSIS; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; FEMALE; GADOLINIUM; KUPFFER CELLS; LIPOPOLYSACCHARIDES; LIVER; LIVER DISEASES; LUNG DISEASES; NEUTROPHILS; PHAGOCYTOSIS; PULMONARY FIBROSIS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0031093775     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199703000-00006     Document Type: Article

References (48)

1. Parrillo JE: Pathogenetic mechanisms of septic shock. N Engl J Med 328:1471-1477, 1993.
2. Rietschel ET, Kirikae T, Schade FU, et al: Bacterial endotoxin: Molecular relationships of structure to activity and function. FASEB J 8:217-225, 1994.
3. Hewett JA, Roth RA: Hepatic and extrahepatic pathobiology of bacterial lipopolysaccharides. Pharmacol Rev 45:381-411, 1993.
4. Hewett JA, Schultze AE, VanCise S, Roth RA: Neutrophil depletion protects against liver injury from bacterial endotoxin. Lab Invest 66:347-361, 1992.
5. Frevert CW, Warner AE: Respiratory distress resulting from acute lung injury in the veterinary patient. J Vet Intern Med 6:154-165, 1992.
6. Windsor ACJ, Mullen PG, Fowler AA, Sugerman HJ: Role of the neutrophil in adult respiratory distress syndrome. Br J Surg 80:10-17, 1993.
7. Hewett JA, Jean PA, Kunkel SL, Roth RA: Relationship between tumor necrosis factor-a and neutrophils in endotoxin-induced liver injury. Am J Physiol 265:G1011-G1015, 1993.
8. Anderson BO, Poggetti RS, Shanley PF, et al: Primed neutrophils injure rat lung through a platelet-activating factor-dependent mechanism. J Surg Res 50:510-514, 1991.
9. Witthaut R, Farhood A, Smith CW, Jaeschke H: Complement and tumor necrosis factor-a contribute to Mac-1 (CD11b/CD18) up-regulation and systemic neutrophil activation during endotoxemia in vivo. J Leukocyte Biol 55:105-111, 1994.
10. Treon SP, Thomas P, Broitman SA: Lipopolysaccharide (LPS) processing by Kupffer cells releases a modified LPS with increased hepatocyte binding and decreased tumor necrosis factor-α stimulatory capacity. Proc Soc Exp Biol Med 202:153-158, 1993.
11. Decker K: Biologically active products of stimulated liver macrophages (Kupffer cells). Eur J Biochem 192:245-261, 1990.
12. Arai M, Mochida S, Ohno A, Ogata I, Fujiwara K: Sinusoidal endothelial cell damage by activated macrophages in rat liver necrosis. Gastroenterology 104:1466-1471, 1993.
13. Iimuro Y, Yamamoto M, Kohno H, Itakura J, Fujii H, Matsumoto Y: Blockade of liver macrophages by gadolinium chloride reduces lethality in endotoxemic rats: Analysis of mechanisms of lethality in endotoxemia. J Leukocyte Biol 55:723-728, 1994.
14. Pearson JM, Brown AP, Schultze AE, Ganey PE, Roth RA: Gadolinium chloride treatment attenuates hepatic platelet accumulation after lipopolysaccharide administration. Shock 5:408-415, 1996.
15. Liu P, McGuire GM, Fisher MA, Farhood A, Smith CW, Jaeschke H: Activation of Kupffer cells and neutrophils for reactive oxygen formation is responsible for endotoxin-enhanced liver injury after hepatic ischemia. Shock 3:56-62, 1995.
16. Tanner A, Keyhani A, Reiner R, Holdstock G, Wright R: Proteolytic enzymes released by liver macrophages may promote hepatic injury in a rat model of hepatic damage. Gastroenterology 80:647-654, 1981.
17. Shibayama Y, Asaka S, Nakata K: Role of activated macrophages in augmentation of endotoxin hepatotoxicity. Exp Toxicol Pathol 45:497-502, 1994.
18. Dean PB, Neimi P, Kivisaari L, Kormano M: Comparative pharmacokinetics of gadolinium DTPA and gadolinium chloride. Invest Radiol 23: S258-S260, 1988.
19. Hardonk MJ, Dijkhuis FWJ, Hulstaert CE, Koudstaal J: Heterogeneity of rat liver and spleen macrophages in gadolinium choloride-induced elimination and repopulation. J Leukocyte Biol 52:296-302, 1992.
20. Sarphie TG, D'Souza NB, Deaciuc IV: Kupffer cell inactivation prevents lipopolysaccharide-induced structural changes in the rat liver sinusoid: An electron-microscopic study. Hepatology 23:788-796, 1996.
21. Hewett JA, Roth RA: The coagulation system, but not circulating fibrinogen, contributes to liver injury in rats exposed to lipopolysaccharide from Gram-negative bacteria. J Pharmacol Exp Ther 272:53-62, 1995.
22. Roth RA: Effect of pneumotoxicants on lactate dehydrogenase activity in airways of rats. Toxicol Appl Pharmacol 57:69-78, 1981.
23. Schultze AE, Wagner JG, White SM, Roth RA: Early indications of monocrotaline pyrrole-induced lung injury in rats. Toxicol Appl Pharmacol 109:41-50, 1991.
24. Goldblum SE, Wu K, Jay M: Lung myeloperoxidase as a measure of pulmonary leukostasis in rabbits. J Appl Physiol 59:1978-1985, 1985.
25. Chang S: Endotoxin-induced pulmonary leukostasis in the rat: Role of platelet-activating factor and tumor necrosis factor. J Lab Clin Med 123:65-72, 1994.
26. Pearson JM, Schultze AE, Jean PA, Roth RA: Platelet participation in liver injury from Gram-negative bacterial lipopolysaccharide in the rat. Shock 4:178-186, 1995.
27. Hewett JA, Roth RA: Dieldrin activates rat neutrophils in vitro. Toxicol Appl Pharmacol 96:269-278, 1988.
28. Babior BM, Kipnes RS, Curnutte JT: Biological defense mechanisms: The production by leukocytes of superoxide, a potential bactericidal agent. J Clin Invest 52:741-744, 1973.
29. Ganey PE, Schultze AE: Depletion of neutrophils and modulation of Kupffer cell function in allyl alcohol-induced hepatotoxicity. Toxicology 99:99-106, 1995.
30. Tauber AI: Protein kinase C and the activation of the human neutrophil NADPH-oxidase. Blood 69:711-720, 1987.
31. Albelda SM, Smith CW, Ward PA: Adhesion molecules and inflammatory injury. FASEB J 8:504-512, 1994.
32. Weiss SJ: Tissue destruction by neutrophils. N Engl J Med 320:365-376, 1989.
33. Westlin WF, Gimbrone MA Jr: Neutrophil-mediated damage to human vascular endothelium: Role of cytokine activation. Am J Pathol 142:117-128, 1993.
34. Ganey PE, Bailie MB, VanCise S, et al: Activated neutrophils from rat injured isolated hepatocytes. Lab Invest 70:53-60, 1994.
35. Lynam EB, Simon SI, Rochon YP, Sklar LA: Lipopolysaccharide enhances CD11b/CD18 function but inhibits neutrophil aggregation. Blood 83:3303-3311, 1994.
36. Erzurum SC, Downey GP, Doherty DE, Schwab B III: Mechanisms of lipopolysaccharide-induced neutrophil retention. J Immunol 149:154-162, 1992.
37. Jaeschke H, Farhood A, Smith CW: Neutrophil-induced liver cell injury in endotoxin shock is a CD11b/CD18-dependent mechanism. Am J Physiol 261:G1051-G1056, 1991.
38. Mawet E, Shiratori Y, Hikiba Y, et al: Cytokine-induced neutrophil chemoattractant release from hepatocytes is modulated by Kupffer cells. Hepatology 23:353-358, 1996.
39. Chang JC, Lesser M: Quantitation of leukocytes in bronchoalveolar lavage from rats after intravascular injection of endotoxin. Am Rev Respir Dis 129:72-75, 1984.
40. Rinaldo JE, Dauber JH, Christman J, Rogers RM: Neutrophil alveolitis following endotoxemia: Enhancement by previous exposure to hyperoxia. Am Rev Respir Dis 130:1065-1071, 1984.
41. Mimura Y, Sakisaka S, Harada M, Sata M, Tanikawa K: Role of hepatocytes in direct clearance of lipopolysaccharide in rats. Gastroenterology 109:1969-1976, 1995.
42. Nill MR, Oberyszyn TM, Ross MS, Oberyszyn AS, Robertson FM: Temporal sequence of pulmonary cytokine gene expression in response to endotoxin in C3H/HeN endotoxin-sensitive and C3H/HeJ endotoxin-resistant mice. J Leukocyte Biol 58:563-574, 1995.
43. Gomez F, Ruiz P, Schreiber AD: Impaired function of macrophage Fcτ receptors and bacterial infection in alcoholic cirrhosis. N Engl J Med 331:1122-1128, 1994.
44. Katz S, Grosfeld JL, Gross K, et al: Impaired bacterial clearance and trapping in obstructive jaundice. Ann Surg 199:14-20, 1984.
45. 3 and Gd-DTPA and their influence on proton magnetic relaxation in rat tissues. Magn Reson Imaging 5:221-231, 1987.
46. Pendino KJ, Meidhof TM, Heck DE, Laskin JD, Laskin DL: Inhibition of macrophages with gadolinium chloride abrogates ozone-induced pulmonary injury and inflammatory mediator production. Am J Respir Cell Mol Biol 13:125-132, 1995.
47. Chang JC, Lesser M: Quantitation of leukocytes in bronchoalveolar lavage samples from rats after intravascular injection of endotoxin. Am Rev Respir Dis 129:72-75, 1984.
48. Rinaldo JE, Dauber JH, Christman J, Rogers RM: Neutrophil alveolitis following endotoxemia: Enhancement by previous exposure to hyperoxia. Am Rev Respir Dis 130:1065-1071, 1984.