Endotoxin stimulates gene expression of ROS-eliminating pathways in rat hepatic endothelial and Kupffer cells

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 270, Issue 4 33-4, 1996, Pages

  Spolarics, Zoltan ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

glucose; GLUT 1; glutathione peroxidase; hepatocytes; hexose monophosphate shunt; hydrogen peroxide; lipopolysaccharide; liver; superoxide anion; superoxide dismutase

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; ENDOTOXIN; GLUCOSE TRANSPORTER; GLUTATHIONE PEROXIDASE; LIPOPOLYSACCHARIDE; MANGANESE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; SELENIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENDOTOXEMIA; GENE EXPRESSION REGULATION; KUPFFER CELL; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; TOXIN ANALYSIS;

EID: 0029878286     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1996.270.4.g660     Document Type: Article

References (43)

1. Arai, K., F. Lee, A. Miyajima, S. Miyatake, N. Arai, and T. Yokota. Cytokines: coordinators of immune and inflammatory responses. Annu. Rev. Biochem. 59: 783-836, 1990.
2. Bautista, A. P., K. Mészáros, J. Bojta, and J. J. Spitzer. Superoxide amon generation in the liver during the early stage of endotoxemia in rats. J. Leukocyte Biol. 48: 123-128, 1990.
3. Bilir, B. M., T. W. L. Gong, V. Kwasiborski, C. S. Shen, C. S. Fillmore, C. M. Berkowitz, and J. J. Gumucio. Liver GLUT-1 expression: an enigma deepens. J. Biol. Chern. 268: 19776-19784, 1993.
4. Chomczynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162- 156-159, 1987.
5. Czaja, M. J., M. L. Schilsky, Y. Xu, P. Schmiedeberg, A. Compton, L. Ridnour, and L. W. Oberley. Induction of MnSOD gene expression in a hepatic model of TNF-α toxicity does not result in increased protein. Am. J. Physiol. 266 (Gastrointest. Liver Physiol. 29): G737-G744, 1994.
6. de Groot, H. Reactive oxygen species in tissue injury. HepatoGastroenterology 41: 328-332, 1994.
7. Dhaunsi, G. S., I. Singh, and C. D. Hanevold. Peroxisomal participation in the cellular response to the oxidative stress of endotoxin. Mol. Cell. Biochem. 126: 25-35, 1993.
8. Dougall, W. C., and H, S. Nick. Manganese Superoxide dismutase: a hepatic acute phase protein regulated by interleukin-6 and glucocorticoids. Endocrinology 129: 2376-2384, 1991.
9. Flohe, L. The glutathione peroxidase reaction: molecular basis of the antioxidant function of selenium in animals. Curr. Top. Cell. Regul. 27: 473-479, 1985.
10. Fridovieh, I. The biology of oxygen radicals. Science Wash. DC 201: 875-880, 1978.
11. Greenberg, J. T., P. Monach, H. C. Jodeph, P. D. Jodephy, and B. Demple. Positive control of global antioxidant defense regulation activated by superoxide-generating agents in Escherichia coli. Proc. Natl. Acad. Sci. USA 87: 6181-6185, 1990.
12. Hamers, M. N., and D. Roos. Oxidative stress in human neutrophilic granulocytes: host defense and self-defense. In: Oxidative Stress, edited by H. Sies. New York: Academic, 1985, p. 351-403.
13. Inoue, M. Protective mechanism against reactive oxygen species. In: The Liver, Biology and Pathobiology, edited by I. M. Arias, J. L. Boyer, W. B. Jakoby, N. Fausto, D. Schacter, and D. A. Shafritz. New York: Raven, 1994, p. 443-459.
14. Jaeschke, H. Enhanced sinusoidal glutathione efflux during endotoxin-indueed oxidant stress in vivo. Am. J. Physiol. 263 (Gastrointest. Liver Physiol. 26): G60-G68, 1992.
15. Jaeschke, H., A. Farhood, A. P. Bautista, Z. Spolarics, and J. J. Spitzer. Complement activates Kupffer cells and neutrophils during reperfusion after hepatic ischemia. Am. J. Physiol. 264 (Gastrointest. Liver Physiol. 27): G801-G809, 1993.
16. Kamata, T., K. Akasaka, H. Ohrui, and H. Meguro. Fluorometric assay of glutathione peroxidase activity in liver and plasma with N-(9-acridinyl)maleimide. Biosci. Biotech. Biochem. 58: 878-880, 1994
17. Kaplowitz, N., T. Y. Aw, and M. Ookhtens. The regulation of hepatic glutathione. Annu. Rev. Pharmacol. Toxicol 25: 715-744, 1985.
18. Karnovsky, M. L., A. Bishop, V. C. P. C. Camerero, M. A. Paz, P. Colepicolo, J. M. C. Ribeiro, and P. M. Gallop. Aspects of the release of Superoxide by leukocytes, and a means by which this is switched off. Environ. Health Perspect. 102: 43-44, 1994.
19. 1 in rat hepatocytes. J. Biol. Chem. 269: 15488-15492, 1994.
20. Kinouchi, H., C. J. Epstein, T. Mizui, E. Carlson, S. F. Chen, and P. K. Chan. Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn Superoxide dismutase. Proc. Natl. Acad. Sci. USA 88: 11158-11162, 1991.
21. Knook, D. L., N. Blansjaar, and E. C. Sleyster. Isolation and characterization of Kupffer and endothelial cells from rat liver. Exp. Cell Res. 109: 317-329, 1977.
22. Lewis-Molock, Y., K. Suzuki, N. Taniguchi, D. H. Nguyen, R. J. Mason, and C. W. White. Lung manganase Superoxide dismutase increases during cytokine-mediated protection against pulmonary oxygen toxicity. Am. J. Respir. Mol. Biol. 10: 133-141, 1994.
23. Li, N., P. S. Reddy, K. Thyagaraju, A. P. Reddy, B. L. Hsu, R. W. Scholz, C. D. Tu, and C. C. Reddy. Elevation of rat liver mRNA for selenium-dependent glutathione peroxidase by selenium deficiency. J. Biol. Chem. 265: 108-113, 1990.
24. McCloskey, T. W., J. A. Todaro, and D. L. Laskin. Lipopolysaccharide treatment of rats alters antigen expression and oxidative metabolism in hepatic macrophages and endothelial cells. Hepatology 16: 191-203, 1992.
25. McCord, J. M. Human disease, free radicals, and the oxidant/ antioxidant balance. Clin. Biochem. 26: 351-357, 1993.
26. McCord, J. M., and I. Fridovieh. Superoxide dismutase: an enzymic function for erythrocuprein (hemocuprein) J. Biol. Chem. 244: 276-287, 1969.
27. Mészáros, K., J. Bojta, A. P. Bautista, C. H. Lang, and J. J. Spitzer. Glucose utilization by Kupffer cells, endothelial cells, and granulocytes in endotoxemic rat liver. Am. J. Physiol. 260 (Gastrointest. Liver Physiol. 23): G7-G12, 1991.
28. Pekala, P., M. Marlow, D. Heuvehnan, and D. Connolly. Regulation of hexose transport in aortic endothelial cells by vascular permeability factor and tumor necrosis factor-ct, but not by insulin. J. Biol. Chem. 265: 18051-18054, 1990.
29. Phan, S. H., D. E. Gannon, J. Varani, U. S. Ryan, and P. A. Ward. Xanthine oxidase activity in rat pulmonary artery endothelial cells and its alteration by activated neutrophils. Am. J. Pathol. 134: 1201-1211, 1989.
30. Shen, Q., S. Chada, C. Whitney, and P. E. Newburger. Regulation of the human cellular glutathione peroxidase gene during in vitro myeloid and monocytic differentiation. Blood 84: 3902-3908, 1994.
31. Sies, H. Hydroperoxides and thiol oxidants in the study of oxidative stress in intact cells and organs. In: Oxidative Stress, edited by H. Sies. New York: Academic, 1985, p. 73-90.
32. Spolarics, Z., A. P. Bautista, and J. J. Spitzer. Primed pentose cycle activity supports production and elimination of Superoxide anion in Kupffer cells from rats treated with endotoxin in vivo. Biochem. Biophys. Acta 1179: 134-140, 1993.
33. Spolarics, Z., and L. Navarro. Endotoxin stimulates the expression of glucose-6-phosphate dehydrogenase in Kupffer and hepatic endothelial cells. J. Leukocyte Biol. 56: 453-457, 1994.
34. Spolarics, Z., P. H. Pekala, G. J. Bagby, and J. J. Spitzer. Brief endotoxemia markedly increases expression of GLUT1 glucose transporter in Kupffer, hepatic endothelial and parenchymal cells. Biochem Biophys. Res. Commun. 193: 1211-1215, 1993.
35. Spolarics, Z., A. Schuler, G. J. Bagby, C. H. Lang, S. Nelson, and J. J. Spitzer. In vivo metabolic response of hepatic nonparen-chymal cells and leukocytes to granulocyte-macrophage colonystimulating factor. J. Leukocyte Biol 51: 360-365, 1992.
36. Spolarics, Z., and J. J. Spitzer. Augmented glucose use and pentose cycle activity in hepatic endothelial cells after in vivo endotoxemia. Hepatology 17: 615-620, 1993.
37. Steinberg, P., H. Schramm, L. Schladt, L. W. Robertson, H. Thomas, and F. Oesch. The distribution, induction and isoenzyme profile of glutathione S-transferase and glutathione peroxidase in isolated rat liver parenchymal, Kupffer and endothelial cells. Biochem. J. 264: 737-744, 1989.
38. Steinkühler, C., M. T. Carri, G. Michel, L. Knoepfel, U. Weser, and G. Rotilio. Copper-dependent metabolism of Cu.Znsuperoxide dismutase in human K562 cells. Biochem. J. 302: 687-694, 1994.
39. Taylor, D. E., A. J. Ghio, and C. A. Pantadosi. Reactive oxygen species produced by liver mitochondria of rats in sepsis. Arch. Biochem. Biophys. 316: 70-76, 1995.
40. Vary, T. C., J. H. Siegel, and A. Rivkind. Clinical and therapeutic significance of metabolic patterns of lactic acidosis. Perspect. Crit. Care 1: 85-132, 1988.
41. Visner, G. A., W. C. Dougall, J. M. Wilson, I. A. Burr, and H. S. Nick. Regulation of manganese Superoxide dismutase by lipopolysaccharide, interleukin-1, and tumor necrosis factor. Role in the acute inflammatory response. J. Biol. Chem. 265: 2856-2864, 1990.
42. White, C. W., K. B. Avraham, P. F. Shanley, and Y. Groner. Transgenic mice with expression of elevated levels of copper-zinc Superoxide dismutase in the lungs are resistant to pulmonary oxygen toxicity. J. Clin. Invest. 87: 2162-2168, 1991.
43. Wong, G. H. W., and D. V. Goeddel. Induction of manganous Superoxide dismutase by tumor necrosis factor: possible protective mechanism. Science Wash. DC 242: 941-944, 1988.