Enhanced expression of fibrillin-1, a constituent of the myocardial extracellular matrix in fibrosis

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 289, Issue 3 58-3, 2005, Pages

  Bouzeghrane, Fatiha ^a   Reinhardt, Dieter P ^b,c   Reudelhuber, Tim L ^a   Thibault, Gaétan ^a  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b UNIVERSITY OF LÜBECK   (Germany)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Angiotensin II; Cardiac fibroblasts; Collagen; Deoxycorticosterone; Fibronectin

Indexed keywords

ALPHA ACTIN; ALPHA8BETA1 INTEGRIN; ANGIOTENSIN; COLLAGEN; DEOXYCORTICOSTERONE ACETATE; DISINTEGRIN; ECHISTATIN; ENDOTHELIN 1; FIBRILLIN 1; FIBRONECTIN; INTEGRIN; IODINE 125; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FIBROBLAST; HEART MUSCLE FIBROSIS; HISTOLOGY; IMMUNOHISTOCHEMISTRY; ISOTOPE LABELING; MALE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; STATISTICAL ANALYSIS; TRANSGENIC MOUSE;

ANGIOTENSIN II; ANIMALS; CELLS, CULTURED; DESOXYCORTICOSTERONE; DISEASE MODELS, ANIMAL; ENDOMYOCARDIAL FIBROSIS; EXTRACELLULAR MATRIX; FIBROBLASTS; INTEGRINS; MALE; MICE; MICE, TRANSGENIC; MICROFILAMENT PROTEINS; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; VASOCONSTRICTOR AGENTS;

EID: 23944453357     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00151.2005     Document Type: Article

References (64)

1. Ahmed MS, Ole E, Vinge LE, Yndestad A, Andersen GO, Andersson Y, Attramadal T, and Attramadal H. Induction of myocardial biglycan in heart failure in rats-an extracellular matrix component targeted by AT(1) receptor antagonism. Cardiovasc Res 60: 557-568, 2003.
2. Ammarguellat F, Larouche I, and Schiffrin EL. Myocardial fibrosis in DOCA-salt hypertensive rats: effect of endothelin ET(A) receptor antagonism. Circulation 103: 319-324, 2001.
3. Bax DV, Bernard SE, Lomas A, Morgan A, Humphries J, Shuttleworth CA, Humphries MJ, and Kielty CM. Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by α5β1 and αvβ3 integrins. J Biol Chem 278: 34605-34616, 2003.
4. Beckstead JH. A simple technique for preservation of fixation-sensitive antigens in paraffin-embedded tissues. J Histochem Cytochem 42: 1127-1134, 1994.
5. Border WA and Noble NA. TGF-β in kidney fibrosis: a target for gene therapy. Kidney Int 51: 1388-1396, 1997.
6. Borg TK, Rubin K, Carver W, Samarel A, and Terracio L. The cell biology of the cardiac interstitium. Trends Cardiovasc Med 6: 65-70, 1996.
7. Bouzeghrane F, Mercure C, Reudelhuber TL, and Thibault G. alpha8beta1 integrin is upregulated in myofibroblasts of fibrotic and scarring myocardium. J Mol Cell Cardiol 36: 343-353, 2004.
8. Brecher P. Angiotensin II and cardiac fibrosis. Trends Cardiovasc Med 6: 193-198, 1996.
9. Conrad CH, Brooks WW, Hayes JA, Sen S, Robinson KG, and Bing OH. Myocardial fibrosis and stiffness with hypertrophy and heart failure in the spontaneously hypertensive rat. Circulation 91: 161-170, 1995.
10. D'Arrigo C, Burl S, Withers AP, Dobson H, Black C, and Boxer M. TGF-beta1 binding protein-like modules of fibrillin-1 and -2 mediate integrin-dependent cell adhesion. Connect Tissue Res 37: 29-51, 1998.
11. Denda S, Reichardt LF, and Muller U. Identification of osteopontin as a novel ligand for the integrin alpha8 beta1 and potential roles for this integrin-ligand interaction in kidney morphogenesis. Mol Biol Cell 9: 1425-1435, 1998.
12. Dubuisson L, Lepreux S, Bioulac-Sage P, Balabaud C, Costa AM, Rosenbaum J, and Desmouliere A. Expression and cellular localization of fibrillin-1 in normal and pathological human liver. J Hepatol 34: 514-522, 2001.
13. Fareh J, Touyz RM, Schiffrin EL, and Thibault G. Altered cardiac endothelin receptors and protein kinase C in deoxycorticosterone-salt hypertensive rats. J Mol Cell Cardiol 32: 665-676, 2000.
14. 2+ modulation. Circ Res 78: 302-311, 1996.
15. Faury G. Function-structure relationship of elastic arteries in evolution: from microfibrils to elastin and elastic fibres. Pathol Biol (Paris) 49: 310-325, 2001.
16. Fujii T, Yau TM, Weisel RD, Ohno N, Mickle DA, Shiono N, Ozawa T, Matsubayashi K, and Li RK. Cell transplantation to prevent heart failure: a comparison of cell types. Ann Thorac Surg 76: 2062-2070, 2003.
17. Guarda E, Katwa LC, Myers PR, Tyagi SC, and Weber KT. Effects of endothelins on collagen turnover in cardiac fibroblasts. Cardiovasc Res 27: 2130-2134, 1993.
18. Hafizi S, Wharton J, Chester AH, and Yacoub MH. Profibrotic effects of endothelin-1 via the ETA receptor in cultured human cardiac fibroblasts. Cell Physiol Biochem 14: 285-292, 2004.
19. Handford PA, Downing AK, Reinhardt DP, and Sakai LY. Fibrillin: from domain structure to supramolecular assembly. Matrix Biol 19: 457-470, 2000.
20. Hein S and Schaper J. The extracellular matrix in normal and diseased myocardium. J Nucl Cardiol 8: 188-196, 2001.
21. Henderson DJ and Copp AJ. Versican expression is associated with chamber specification, septation, and valvulogenesis in the developing mouse heart. Circ Res 83: 523-532, 1998.
22. Isogai Z, Ono RN, Ushiro S, Keene DR, Chen Y, Mazzieri R, Charbonneau NL, Reinhardt DP, Rifkin DB, and Sakai LY. Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein. J Biol Chem 278: 2750-2757, 2003.
23. Janicki JS and Brower GL. The role of myocardial fibrillar collagen in ventricular remodeling and function. J Card Fail 8: S319-S325, 2002.
24. Jensen SA, Reinhardt DP, Gibson MA, and Weiss AS. Protein interaction studies of MAGP-1 with tropoelastin and fibrillin-1. J Biol Chem 276: 39661-39666, 2001.
25. Junqueira LCU, Bignolas G, and Brentani RR. Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections. Histochem J 11: 447-455, 1979.
26. Kapoun AM, Liang F, O'Young G, Damm DL, Quon D, White RT, Munson K, Lam A, Schreiner GF, and Protter AA. B-type natriuretic peptide exerts broad functional opposition to transforming growth factor-beta in primary human cardiac fibroblasts: fibrosis, myofibroblast conversion, proliferation, and inflammation. Circ Res 94: 453-461, 2004.
27. Kielty CM, Sherratt MJ, and Shuttleworth CA. Elastic fibres. J Cell Sci 115: 2817-2828, 2002.
28. Kielty CM, Wess TJ, Haston L, Ashworth JL, Sherratt MJ, and Shuttleworth CA. Fibrillin-rich microfibrils: elastic biopolymers of the extracellular matrix. J Muscle Res Cell Motil 23: 581-596, 2002.
29. Kim S and Iwao H. Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases. Pharmacol Rev 52: 11-34, 2000.
30. Kissin EY, Lemaire R, Korn JH, and Lafyatis R. Transforming growth factor beta induces fibroblast fibrillin-1 matrix formation. Arthritis Rheum 46: 3000-3009, 2002.
31. Li L, Fink GD, Watts SW, Northcott CA, Galligan JJ, Pagano PJ, and Chen AF. Endothelin-1 increases vascular Superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension. Circulation 107: 1053-1058, 2003.
32. Lijnen PJ, Petrov VV, and Fagard RH. Induction of cardiac fibrosis by transforming growth factor-β1. Mol Genet Metab 71: 418-435, 2000.
33. Lorena D, Darby IA, Reinhardt DP, Sapin V, Rosenbaum J, and Desmouliere A. Fibrillin-1 expression in normal and fibrotic rat liver and in cultured hepatic fibroblastic cells: modulation by mechanical stress and role in cell adhesion. Lab Invest 84: 203-212, 2004.
34. Lu M, Munger JS, Steadele M, Busald M, Tellier M, and Schnapp LM. Integrin α8β1 mediates adhesion to LAP-TGFβ1. J Cell Sci 115: 4641-4648, 2002.
35. Matsubara LS, Matsubara BB, Okoshi MP, Cicogna AC, and Janicki JS. Alterations in myocardial collagen content affect rat papillary muscle function. Am J Physiol Heart Circ Physiol 279: H1534-H1539, 2000.
36. McEwan PE, Gray GA, Sherry L, Webb DJ, and Kenyon C. Differential effects of angiotensin II on cardiac cell proliferation and intramyocardial perivascular fibrosis in vivo. Circulation 98: 2765-2773, 1998.
37. Medeiros DM, Velleman SG, Jarrold BB, Shiry LJ, Radin MJ, and McCune SA. Ontogeny of enhanced decorin levels and distribution within myocardium of failing hearts. Connect Tissue Res 43: 32-43, 2002.
38. Moncrieff J, Lindsay MM, and Dunn FG. Hypertensive heart disease and fibrosis. Curr Opin Cardiol 19: 326-331, 2004.
39. Nakajima Y, Miyazono K, Kato M, Takase M, Yamagishi T, and Nakamura H. Extracellular fibrillar structure of latent TGF beta binding protein-1: role in TGF beta-dependent endothelial-mesenchymal transformation during endocardial cushion tissue formation in mouse embryonic heart. J Cell Biol 136: 193-204, 1997.
40. Pereira L, Andrikopoulos K, Tian J, Lee SY, Keene DR, Ono R, Reinhardt DP, Sakai LY, Biery NJ, Bunton T, Dietz HC, and Ramirez F. Targetting of the gene encoding fibrillin-1 recapitulates the vascular aspect of Marfan syndrome. Nat Genet 17: 218-222, 1997.
41. Pfaff M, Reinhardt DP, Sakai LY, and Timpl R. Cell adhesion and integrin binding to recombinant human fibrillin-1. FEBS Lett 384: 247-250, 1996.
42. Rhaleb NE, Peng H, Harding P, Tayeh M, LaPointe MC, and Carretero OA. Effect of N-acetyl-seryl-aspartyl-lysyl-proline on DNA and collagen synthesis in rat cardiac fibroblasts. Hypertension 37: 827-832, 2001.
43. Robinson PN and Booms P. The molecular pathogenesis of the Marfan syndrome. Cell Mol Life Sci 58: 1698-1707, 2001.
44. Ross RS. The extracellular connections: the role of integrins in myocardial remodeling. J Card Fail 8: S326-S331, 2002.
45. Saharinen J, Hyytiainen M, Taipale J, and Keski-Oja J. Latent transforming growth factor-β binding proteins (LTBPs)-structural extracellular matrix proteins for targeting TGF-β action. Cytokine Growth Factor Rev 10: 99-117, 1999.
46. Sakai LY, Keene DR, and Engvall E. Fibrillin, a new 350-kD glycoprotein, is a component of extracellular microfibrils. J Cell Biol 103: 2499-2509, 1986.
47. Sakamoto H, Broekelmann T, Cheresh DA, Ramirez F, Rosenbloom J, and Mecham RP. Cell-type specific recognition of RGD- and non-RGD-containing cell binding domains in fibrillin-1. J Biol Chem 271: 4916-4922, 1996.
48. Schnapp LM, Hatch N, Ramos DM, Klimanskaya IV, Sheppard D, and Pytela R. The human integrin α8β1 functions as a receptor for tenascin, fibronectin, and vitronectin. J Biol Chem 270: 23196-23202, 1995.
49. Schoen FJ. Aortic valve structure-function correlations: role of elastic fibers no longer a stretch of the imagination. J Heart Valve Dis 6: 1-6, 1997.
50. Scott JE. Structure and function in extracellular matrices depend on interactions between anionic glycosaminoglycans. Pathol Biol (Paris) 49: 284-289, 2001.
51. Serini G and Gabbiani G. Mechanisms of myofibroblasts activity and phenotypic modulation. Exp Cell Res 250: 273-283, 1999.
52. Siwik DA, Pagano PJ, and Colucci WS. Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts. Am J Physiol Cell Physiol 280: C53-C60, 2001.
53. Steven P, Paulsen F, and Tillmann B. Orcein-picroindigocarmine-a new multiple stain. Arch Histol Cytol 63: 397-400, 2000.
54. Taylor PM, Batten P, Brand NG, Thomas PS, and Yacoub MH. The cardiac valve interstitial cell. Int J Biochem Cell Biol 35: 113-118, 2003.
55. Thibault G. SDS-stable complexes between echistatin and RDG-dependent integrins: a novel approach to study intregrins. Mol Pharmacol 58: 1137-1145, 2000.
56. 1-integrin in cardiac fibroblasts by angiotensin II and transforming growth factor-β1. Am J Physiol Cell Physiol 281: C1457-C1467, 2001.
57. 3 integrin antagonists. J Pharmacol Exp Ther 296: 690-606, 2001.
58. Tiedemann K, Batge B, Muller PK, and Reinhardt DP. Interactions of fibrillin-1 with heparin/heparan sulfate, implications for microfibrillar assembly. J Biol Chem 276: 36035-36042, 2001.
59. Touyz RM and Schiffrin EL. Reactive oxygen species in vascular biology: implications in hypertension. Histochem Cell Biol 122: 339-352, 2004.
60. Van Kats JP, Methot D, Paradis P, Silversides DW, and Reudelhuber TL. Use of a biological peptide pump to study chronic peptide hormone action in transgenic mice. Direct and indirect effects of angiotensin II on the heart. J Biol Chem 276: 44012-44017, 2001.
61. Vracko R, Thorning D, and Frederickson RG. Spatial arrangements of microfibrils in myocardial scars: application of antibody to fibrillin. J Mol Cell Cardiol 22: 749-757, 1990.
62. Weber E, Rossi A, Solito R, Sacchi G, Agliano' M, and Gerli R. Focal adhesion molecules expression and fibrillin deposition by lymphatic and blood vessel endothelial cells in culture. Microvasc Res 64: 47-55, 2002.
63. Weber KT, Swamynathan SK, Guntaka RV, and Sun Y. Angiotensin II and extracellular matrix homeostasis. Int J Biochem Cell Biol 31: 395-403, 1999.
64. Yamamoto K, Masuyama T, Sakata Y, Nishikawa N, Mano T, Yoshida J, Miwa T, Sugawara M, Yamaguchi Y, Ookawara T, Suzuki K, and Hori M. Myocardial stiffness is determined by ventricular fibrosis, but not by compensatory or excessive hypertrophy in hypertensive heart. Cardiovasc Res 55: 76-82, 2002.