Impact of fever-range thermal stress on lymphocyte-endothelial adhesion and lymphocyte trafficking

Immunological Investigations

Volumn 34, Issue 3, 2005, Pages 295-323

  Appenheimer, Michelle M ^a   Chen, Qing ^a   Girard, Rachael A ^a   Wang, Wan Chao ^a   Evans, Sharon S ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Adhesion molecules; Endothelium; Fever; IL 6; Lymphocyte trafficking

Indexed keywords

ALPHA INTERFERON; CD31 ANTIGEN; CELL ADHESION MOLECULE; CHEMOKINE; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR4; CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GAMMA INTERFERON; HEAT SHOCK PROTEIN 70; INTERCELLULAR ADHESION MOLECULE 2; INTERLEUKIN 10; INTERLEUKIN 11; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 6; INTERLEUKIN 8; L SELECTIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MONOCYTE CHEMOTACTIC PROTEIN 1; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; RANTES; SECONDARY LYMPHOID TISSUE CHEMOKINE; STROMAL CELL DERIVED FACTOR 1; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

CELL ADHESION; CELL MIGRATION; CELL SURVIVAL; CHEMOTAXIS; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; DENDRITIC CELL; ENDOTHELIUM CELL; EVOLUTION; FEVER; GENETIC CONSERVATION; HUMAN; IMMUNE RESPONSE; LYMPHOCYTE HOMING; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE TRANSFER; LYMPHOID ORGAN; NONHUMAN; PRIORITY JOURNAL; REVIEW; STRESS; TEMPERATURE ACCLIMATIZATION; THERMAL ANALYSIS;

ANIMALS; CELL ADHESION; CELL MOVEMENT; ENDOTHELIUM; FEVER; HUMANS; HYPERTHERMIA, INDUCED; LYMPHOCYTES; LYMPHOID TISSUE;

EID: 23844545139     PISSN: 08820139     EISSN: 15324311     Source Type: Journal    
DOI: 10.1081/IMM-200064501     Document Type: Review

References (141)

1. Alessi, D. R., Cuenda, A., Cohen, P., Dudley, D. T., Saltiel, A. R. (1995). PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270:27489-27494.
2. Andrew, D. P., Berlin, C., Honda, S., Yoshino, T., Hamann, A., Holzmann, B., Kilshaw, P. J., Butcher, E. C. (1994). Distinct but overlapping epitopes are involved in alpha 4 beta 7-mediated adhesion to vascular cell adhesion molecule-1, mucosal addressin-1, fibronectin, and lymphocyte aggregation. J. Immunol. 153:3847-3861.
3. Azocar, J., Yunis, E. J., Essex, M. (1982). Sensitivity of human natural killer cells to hyperthermia. Lancet 1:16-17.
4. Bennett, B. L., Sasaki, D. T., Murray, B. W., O'Leary, E. C., Sakata, S. T., Xu, W., Leisten, J. C., Motiwala, A., Pierce, S., Satoh, Y., Bhagwat, S. S., Manning, A. M., Anderson, D. W. (2001). SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc. Natl. Acad. Sci. U. S. A. 98:13681-13686.
5. Berlin, C., Berg, E. L., Briskin, M. J., Andrew, D. P., Kilshaw, P. J., Holzmann, B., Weissman, I. L., Hamann, A., Butcher, E. C. (1993). Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. Cell 74:185-195.
6. Berman, J. D., Neva, F. A. (1981). Effect of temperature on multiplication of Leishmania amastigotes within human monocyte-derived macrophages in vitro. Am. J. Trop. Med. Hyg. 30:318-321.
7. Bernheim, H. A., Kluger, M. J. (1976). Fever: effect of drug-induced antipyresis on survival. Science 193:237-239.
8. Bernheim, H. A., Bodel, P. T., Askenase, P. W., Atkins, E. (1978). Effects of fever on host defense mechanisms after infection in the lizard Dipsosaurus dorsalis. Br. J. Exp. Pathol. 59:76-84.
9. Blatteis, C. M. (2003). Fever: pathological or physiological, injurious or beneficial? J. Therm. Biol. 28:1-13.
10. Boeye, A., Delaet, I., Brioen, P. (1994). Antibody neutralization of picornaviruses: can fever help? Trends Microbiol. 2:255-257.
11. Bryant, R. E., Hood, A. F., Hood, C. E., Koenig, M. G. (1971). Factors affecting mortality of gram-negative rod bacteremia. Arch. Intern. Med. 127:120-128.
12. Burd, R., Dziedzic, T. S., Xu, Y., Caligiuri, M. A., Subjeck, J. R., Repasky, E. A. (1998). Tumor cell apoptosis, lymphocyte recruitment and tumor vascular changes are induced by low temperature, long duration (fever-like) whole body hyperthermia. J. Cell. Physiol. 177:137-147.
13. Butcher, E. C., Picker, L. J. (1996). Lymphocyte homing and homeostasis. Science 272:60-66.
14. Butcher, E., Scollay, R., Weissman, I. (1979a). Evidence of continuous evolutionary change in structures mediating adherence of lymphocytes to specialised venules. Nature 280:496-498.
15. Butcher, E., Scollay, R., Weissman, I. (1979b). Lymphocyte-high endothelial venule interactions: examination of species specificity. Adv. Exp. Med. Biol. 114:65-72.
16. Butcher, E. C., Williams, M., Youngman, K., Rott, L., Briskin, M. (1999). Lymphocyte trafficking and regional immunity. Adv. Immunol. 72:209-253.
17. Campbell, J. J., Butcher, E. C. (2000). Chemokines in tissue-specific and microenvironment-specific lymphocyte homing. Curr. Opin. Immunol. 12:336-341.
18. Carpen, O., Pallai, P., Staunton, D. E., Springer, T. A. (1992). Association of intercellular adhesion molecule-1 (ICAM-1) with actin-containing cytoskeleton and alpha-actinin. J. Cell Biol. 118:1223-1234.
19. Chang, C. C., Wu, J. M. (1991). Modulation of antiviral activity of interferon and 2′,5′-oligoadenylate synthetase gene expression by mild hyperthermia (39.5°C) in cultured human cells. J. Biol. Chem. 266:4605-4612.
20. Chantakru, S., Miller, C., Roach, L. E., Kuziel, W. A, Maeda, N., Wang, W. C., Evans, S. S., Croy, B. A. (2002). Contributions from self-renewal and trafficking to the uterine NK cell population of early pregnancy. J. Immunol. 168:22-28.
21. Chantakru, S., Wang, W. C., van den Heuvel, M., Bashar, S., Simpson, A., Chen, Q., Croy, B. A., Evans, S. S. (2003). Coordinate regulation of lymphocyte-endothelial interactions by pregnancy-associated hormones. J. Immunol. 171:4011-4019.
22. Chen, Q., Wang, W. C., Evans, S. S. (2003). Tumor microvasculature as a barrier to antitumor immunity. Cancer Immunol. Immunother. 52:670-679.
23. Chen, Q., Wang, W. C., Bruce, R., Li, H., Schleider, D. M., Mulbury, M. J., Bain, M. D., Wallace, P. K., Baumann, H., Evans, S. S. (2004). Central role of IL-6 receptor signal-transducing chain gp130 in activation of L-selectin adhesion by fever-range thermal stress. Immunity 20:59-70.
24. Choi, J., Enis, D. R., Koh, K. P., Shiao, S. L., Pober, J. S. (2004). T lymphocyte-endothelial cell interactions. Annu. Rev. Immunol. 22:683-709.
25. Clark, H. F., Gurney, A. L., Abaya, E., Baker, K., Baldwin, D., Brush, J., Chen, J., Chow, B., Chui, C., Crowley, C., Currell, B., Deuel, B., Dowd, P., Eaton, D., Foster, J., Grimaldi, C., Gu, Q., Hass, P. E., Heldens, S., Huang, A., Kim, H. S., Klimowski, L., Jin, Y., Johnson, S., Lee, J., Lewis, L., Liao, D., Mark, M., Robbie, E., Sanchez, C., Schoenfeld, J., Seshagiri, S., Simmons, L., Singh, J., Smith, V., Stinson, J., Vagts, A., Vandlen, R., Watanabe, C., Wieand, D., Woods, K., Xie, M. H., Yansura, D., Yi, S., Yu, G., Yuan, J., Zhang, M., Zhang, Z., Goddard, A., Wood, W. I., Godowski, P., Gray, A. (2003). The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. Genome Res. 13:2265-2270.
26. Covert, J. B., Reynolds, W. W. (1977). Survival value of fever in fish. Nature 267:43-45.
27. Cressman, D. E., Greenbaum, L. E., DeAngelis, R. A., Ciliberto, G., Furth, E. E., Poli, V., Taub, R. (1996). Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice. Science 274:1379-1383.
28. Dean, J. L., Brook, M., Clark, A. R., Saklatvala, J. (1999). p38 Mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes. J. Biol. Chem. 274:264-269.
29. Delaet, I., Boeye, A. (1993). Monoclonal antibodies that disrupt poliovirus only at fever temperatures. J. Virol. 67:5299-5302.
30. Dewhirst, M. W., Prosnitz, L., Thrall, D., Prescott, D., Clegg, S., Charles, C., MacFall, J., Rosner, G., Samulski, T., Gillette, E., LaRue, S. (1997). Hyperthermic treatment of malignant diseases: current status and a view toward the future. Semin. Oncol. 24:616-625.
31. Di, Y. P., Repasky, E. A., Subjeck, J. R. (1997). Distribution of HSP70, protein kinase C, and spectrin is altered in lymphocytes during a fever-like hyperthermia exposure. J. Cell. Physiol. 172:44-54.
32. Doran, T. F., De Angelis, C., Baumgardner, R. A., Mellits, E. D. (1989). Acetaminophen: more harm than good for chickenpox? J. Pediatr. 114:1045-1048.
33. Downing, J. F., Taylor, M. W. (1987). The effect of in vivo hyperthermia on selected lymphokines in man. Lymphokine Res. 6:103-109.
34. Downing, J. F., Taylor, M. W., Wei, K. M., Elizondo, R. S. (1987). In vivo hyperthermia enhances plasma antiviral activity and stimulates peripheral lymphocytes for increased synthesis of interferon-gamma. J. Interferon Res. 7:185-193.
35. Downing, J. F., Martinez-Valdez, H., Elizondo, R. S., Walker, E. B., Taylor, M. W. (1988). Hyperthermia in humans enhances interferon-gamma synthesis and alters the peripheral lymphocyte population. J. Interferon Res. 8:143-150.
36. Duff, G. W., Durum, S. K. (1982). Fever and immunoregulation: hyperthermia, interleukins 1 and 2, and T-cell proliferation. Yale J. Biol. Med. 55:437-442.
37. Dwir, O., Kansas, G. S., Alon, R. (2001). Cytoplasmic anchorage of L-selectin controls leukocyte capture and rolling by increasing the mechanical stability of the selectin tether. J. Cell Biol. 155:145-156.
38. Elemer, G. S., Edgington, T. S. (1994). Microfilament reorganization is associated with functional activation of alpha M beta 2 on monocytic cells. J. Biol. Chem. 269:3159-3166.
39. Ensor, J. E., Crawford, E. K., Hasday, J. D. (1995). Warming macrophages to febrile range destabilizes tumor necrosis factor-alpha mRNA without inducing heat shock. Am. J. Physiol. 269:C1140-C1146.
40. Esposito, A. L. (1984). Aspirin impairs antibacterial mechanisms in experimental pneumococcal pneumonia. Am. Rev. Respir. Dis. 130:857-862.
41. Evans, S. S., Frey, M., Schleider, D. M., Bruce, R. A., Wang, W. C., Repasky, E. A., Appenheimer, A. M. M. (1998). Leukocyte-endothelial cell interactions in tumor immunity. In: Croce, E. M. A. C., ed. The Biology of Tumors. New York: Plenum Press, 273-286.
42. Evans, S. S., Schleider, D. M., Bowman, L. A., Francis, M. L., Kansas, G. S., Black, J. D. (1999). Dynamic association of L-selectin with the lymphocyte cytoskeletal matrix. J. Immunol. 162:3615-3624.
43. Evans, S. S., Bain, M. D., Wang, W. C. (2000). Fever-range hyperthermia stimulates alpha4beta7 integrin-dependent lymphocyte-endothelial adhesion. Int. J. Hypertherm. 16:45-59.
44. Evans, S. S., Wang, W. C., Bain, M. D., Burd, R., Ostberg, J. R., Repasky, E. A. (2001). Fever-range hyperthermia dynamically regulates lymphocyte delivery to high endothelial venules. Blood 97:2727-2733.
45. Fabbri, M., Bianchi, E., Fumagalli, L., Pardi, R. (1999). Regulation of lymphocyte traffic by adhesion molecules. Inflamm. Res. 48:239-246.
46. Fairchild, K. D., Viscardi, R. M., Hester, L., Singh, I. S., Hasday, J. D. (2000). Effects of hypothermia and hyperthermia on cytokine production by cultured human mononuclear phagocytes from adults and newborns. J. Interferon Cytokine Res. 20:1049-1055.
47. Favata, M. F., Horiuchi, K. Y., Manos, E. J., Daulerio, A. J., Stradley, D. A., Feeser, W. S., Van Dyk, D. E., Pitts, W. J., Earl, R. A., Hobbs, F., Copeland, R. A., Magolda, R. L., Scherle, P. A., Trzaskos, J. M. (1998). Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J. Biol. Chem. 273:18623-18632.
48. Frey, M., Packianathan, N. B., Fehniger, T. A., Ross, M. E., Wang, W. C., Stewart, C. C., Caligiuri, M. A., Evans, S. S. (1998). Differential expression and function of L-selectin on CD56bright and CD56dim natural killer cell subsets. J. Immunol. 161:400-408.
49. Gallatin, W. M., Weissman, I. L., Butcher, E. C. (1983). A cell-surface molecule involved in organ-specific homing of lymphocytes. Nature 304:30-34.
50. Gallucci, R. M., Simeonova, P. P., Matheson, J. M., Kommineni, C., Guriel, J. L., Sugawara, T., Luster, M. I. (2000). Impaired cutaneous wound healing in interleukin-6-deficient and immunosuppressed mice. FASEB J. 14:2525-2531.
51. Girard, J. P., Springer, T. A. (1995). High endothelial venules (HEVs): specialized endothelium for lymphocyte migration. Immunol. Today 16:449-457.
52. Goldsby, R. A., Kindt, T. J., Osborne, B. A. (2000). Leukocyte migration and inflammation. Kuby Immunology. 4th ed. New York: W. H. Freeman and Company, 371-395.
53. Hamann, A., Andrew, D. P., Jablonski-Westrich, D., Holzmann, B., Butcher, E. C. (1994). Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo. J. Immunol. 152:3282-3293.
54. Harris, J. W., Meneses, J. J. (1978). Effects of hyperthermia on the production and activity of primary and secondary cytolytic T-lymphocytes in vitro. Cancer Res. 38:1120-1126.
55. Hasday, J. D., Singh, I. S. (2000). Fever and the heat shock response: distinct, partially overlapping processes. Cell Stress Chaperones 5:471-480.
56. Hasday, J. D., Fairchild, K. D., Shanholtz, C. (2000). The role of fever in the infected host. Microbes Infect. 2:1891-1904.
57. Hasday, J. D., Bannerman, D., Sakarya, S., Cross, A. S., Singh, I. S., Howard, D., Drysdale, B. E., Goldblum, S. E. (2001). Exposure to febrile temperature modifies endothelial cell response to tumor necrosis factor-alpha. J. Appl. Physiol. 90:90-98.
58. Hasday, J. D., Garrison, A., Singh, I. S., Standiford, T., Ellis, G. S., Rao, S., He, J. R., Rice, P., Frank, M., Goldblum, S. E., Viscardi, R. M. (2003). Febrile-range hyperthermia augments pulmonary neutrophil recruitment and amplifies pulmonary oxygen toxicity. Am. J. Pathol. 162:2005-2017.
59. Haveman, J., Geerdink, A. G., Rodermond, H. M. (1996). Cytokine production after whole body and localized hyperthermia. Int. J. Hypertherm. 12:791-800.
60. Hedges, S. B. (2002). The origin and evolution of model organisms. Nat. Rev., Genet. 3:838-849.
61. Heiska, L., Kantor, C., Parr, T., Critchley, D. R., Vilja, P., Gahmberg, C. G., Carpen, O. (1996). Binding of the cytoplasmic domain of intercellular adhesion molecule-2 (ICAM-2) to alpha-actinin. J. Biol. Chem. 271:26214-26219.
62. Hemmerich, S., Butcher, E. C., Rosen, S. D. (1994). Sulfation-dependent recognition of high endothelial venules (HEV)-ligands by L-selectin and MECA 79, and adhesion-blocking monoclonal antibody. J. Exp. Med. 180:2219-2226.
63. Hendriks, H. R., Duijvestijn, A. M., Kraal, G. (1987). Rapid decrease in lymphocyte adherence to high endothelial venules in lymph nodes deprived of afferent lymphatic vessels. Eur. J. Immunol. 17:1691-1695.
64. Heron, I., Berg, K. (1978). The actions of interferon are potentiated at elevated temperature. Nature 274:508-510.
65. Hobohm, U. (2001). Fever and cancer in perspective. Cancer Immunol. Immunother. 50:391-396.
66. Hughes, C. S., Repasky, E. A., Bankert, R. B., Johnson, R. J., Subjeck, J. R. (1987). Effects of hyperthermia on spectrin expression patterns of murine lymphocytes. Radiat. Res. 112:116-123.
67. Hurst, S. M., Wilkinson, T. S., McLoughlin, R. M., Jones, S., Horiuchi, S., Yamamoto, N., Rose-John, S., Fuller, G. M., Topley, N., Jones, S. A. (2001). Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity 14:705-714.
68. International Chicken Genome Sequencing Consortium. (2004). Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature 432:695-716. [Article].
69. Jampel, H. D., Duff, G. W., Gershon, R. K., Atkins, E., Durum, S. K. (1983). Fever and immunoregulation. III. Hyperthermia augments the primary in vitro humoral immune response. J. Exp. Med. 157:1229-1238.
70. Jiang, Q., DeTolla, L., Kalvakolanu, I., Fitzgerald, B., Hasday, J. D. (1999a). Fever upregulates expression of pyrogenic cytokines in endotoxin-challenged mice. Am. J. Physiol. 276:R1653-R1660.
71. Jiang, Q., DeTolla, L., van Rooijen, N., Singh, I. S., Fitzgerald, B., Lipsky, M. M., Kane, A. S., Cross, A. S., Hasday, J. D. (1999b). Febrile-range temperature modifies early systemic tumor necrosis factor alpha expression in mice challenged with bacterial endotoxin. Infect. Immun. 67:1539-1546.
72. Jiang, Q., Cross, A. S., Singh, I. S., Chen, T. T., Viscardi, R. M., Hasday, J. D. (2000). Febrile core temperature is essential for optimal host defense in bacterial peritonitis. Infect. Immun. 68:1265-1270.
73. Jones, S. A., Rose-John, S. (2002). The role of soluble receptors in cytokine biology: the agonistic properties of the sIL-6R/IL-6 complex. Biochim. Biophys. Acta 1592:251-263.
74. Jostock, T., Mullberg, J., Ozbek, S., Atreya, R., Blinn, G., Voltz, N., Fischer, M., Neurath, M. F., Rose-John, S. (2001). Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses. Eur. J. Biochem. 268:160-167.
75. Kamata, T., Puzon, W., Takada, Y. (1995). Identification of putative ligand-binding sites of the integrin alpha 4 beta 1 (VLA-4, CD49d/CD29). Biochem. J. 305 (Pt. 3):945-951.
76. Kansas, G. S., Ley, K., Munro, J. M., Tedder, T. F. (1993). Regulation of leukocyte rolling and adhesion to high endothelial venules through the cytoplasmic domain of L-selectin. J. Exp. Med. 177:833-838.
77. Kashiwazaki, M., Tanaka, T., Kanda, H., Ebisuno, Y., Izawa, D., Fukuma, N., Akimitsu, N., Sekimizu, K., Monden, M., Miyasaka, M. (2003). A high endothelial venule-expressing promiscuous chemokine receptor DARC can bind inflammatory, but not lymphoid, chemokines and is dispensable for lymphocyte homing under physiological conditions. Int. Immunol. 15:1219-1227.
78. Kershaw, D. B., Beck, S. G., Wharram, B. L., Wiggins, J. E., Goyal, M., Thomas, P. E., Wiggins, R. C. (1997). Molecular cloning and characterization of human podocalyxin-like protein. Orthologous relationship to rabbit PCLP1 and rat podocalyxin. J. Biol. Chem. 272:15708-15714.
79. Klatersky, J. (1971). Etude experimentale et clinique des effets favorables et defavorables de la fievre et de l'administration de corticoides au cours d'infectons bacteriennes. Acta Clin. 26.
80. Kluger, M. J. (1991). Fever: role of pyrogens and cryogens. Physiol. Rev. 71:93-127.
81. Kluger, M., Kazac, W., Conn, C. A., Leon, L. R., Soszynski, D. (1996). The adaptive value of fever. In: Mackowiak, P., ed. Fever: Basic Mechanisms and Management. New York: Raven Press, 255-266.
82. Kluger, M. J., Kozak, W., Conn, C. A., Leon, L. R., Soszynski, D. (1998). Role of fever in disease. Ann. N.Y. Acad. Sci. 856:224-233.
83. Kraybill, W. G., Olenki, T., Evans, S. S., Ostberg, J. R., O'Leary, K. A., Gibbs, J. F., Repasky, E. A. (2002). A phase I study of fever-range whole body hyperthermia (FR-WBH) in patients with advanced solid tumours: correlation with mouse models. Int. J. Hypertherm. 18:253-266.
84. Kurosawa, S., Kobune, F., Okuyama, K., Sugiura, A. (1987). Effects of antipyretics in rinderpest virus infection in rabbits. J. Infect. Dis. 155:991-997.
85. Lederman, H. M., Brill, C. R., Murphy, P. A. (1987). Interleukin 1-driven secretion of interleukin 2 is highly temperature-dependent. J. Immunol. 138:3808-3811.
86. Leid, J. G., Steeber, D. A., Tedder, T. F., Jutula, M. A. (2001). Antibody binding to a conformation-dependent epitope induces L-selectin association with the detergent-resistant cytoskeleton. J. Immunol. 166:4899-4907.
87. Leid, J. G., Speer, C. A., Jutila, M. A. (2002). Ultrastructural examination of cytoskeletal linkage of L-selectin and comparison of L-selectin cytoskeletal association to that of other human and bovine lymphocyte surface antigens. Cell. Immunol. 215:219-231.
88. Leshchinsky, T. V., Klasing, K. C. (2001). Divergence of the inflammatory response in two types of chickens. Dev. Comp. Immunol. 25:629-638.
89. Li, C. Y., Dewhirst, M. W. (2002). Hyperthermia-regulated immunogene therapy. Int. J. Hypertherm. 18:586-596.
90. Longrigg, J. (1998). ed. Greek Medicine: From the Heroic to the Hellenistic: A Source Book. New York: Routledge.
91. Mackowiak, P. A. (1994). Fever: blessing or curse? A unifying hypothesis. Ann. Intern. Med. 120:1037-1040.
92. Mackowiak, P. A. (2000). Physiological rationale for suppression of fever. Clin. Infect. Dis. 31 (Suppl. 5):S185-S189.
93. Manthous, C. A., Hall, J. B., Olson, D., Singh, M., Chatila, W., Pohlman, A., Kushner, R., Schmidt, G. A., Wood, L. D. (1995). Effect of cooling on oxygen consumption in febrile critically ill patients. Am. J. Respir. Crit. Care Med. 151:10-14.
94. Mebius, R. E., Streeter, P. R., Breve, J., Duijvestijn, A. M., Kraal, G. (1991). The influence of afferent lymphatic vessel interruption on vascular addressin expression. J. Cell Biol. 115:85-95.
95. Michie, S. A., Streeter, P. R., Bolt, P. A., Butcher, E. C., Picker, L. J. (1993). The human peripheral lymph node vascular addressin. An inducible endothelial antigen involved in lymphocyte homing. Am. J. Pathol. 143:1688-1698.
96. Miyasaka, M., Tanaka, T. (2004). Lymphocyte trafficking across high endothelial venules: dogmas and enigmas. Nat. Rev., Immunol. 4:360-370.
97. Muller-Newen, G., Kuster, A., Hemmann, U., Keul, R., Horsten, U., Martens, A., Graeve, L., Wijdenes, J., Heinrich, P. C. (1998). Soluble IL-6 receptor potentiates the antagonistic activity of soluble gp130 on IL-6 responses. J. Immunol. 161:6347-6355.
98. Nahes, G. G., Tannieres, M. L., Lennon, J. F. (1971). Direct measurement of leukocyte motility: effects of pH and temperature. Proc. Soc. Exp. Biol. Med. 138:350-352.
99. Nakamura, Y., Komano, H., Nakauchi, H. (1993). Two alternative forms of cDNA encoding CD34. Exp. Hematol. 21:236-242.
100. Narazaki, M., Yasukawa, K., Saito, T., Ohsugi, Y., Fukui, H., Koishihara, Y., Yancopoulos, G. D., Taga, T., Kishimoto, T. (1993). Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130. Blood 82:1120-1126.
101. Ostberg, J. R., Patel, R., Repasky, E. A. (2000a). Regulation of immune activity by mild (fever-range) whole body hyperthermia: effects on epidermal Langerhans cells. Cell Stress Chaperones 5:458-461.
102. Ostberg, J. R., Taylor, S. L., Baumann, H., Repasky, E. A. (2000b). Regulatory effects of fever-range whole-body hyperthermia on the LPS-induced acute inflammatory response. J. Leukoc. Biol. 68:815-820.
103. Ostberg, J. R., Gellin, C., Patel, R., Repasky, E. A. (2001). Regulatory potential of fever-range whole body hyperthermia on Langerhans cells and lymphocytes in an antigen-dependent cellular immune response. J. Immunol. 167:2666-2670.
104. Ostberg, J. R., Kaplan, K. C., Repasky, E. A. (2002). Induction of stress proteins in a panel of mouse tissues by fever-range whole body hyperthermia. Int. J. Hypertherm. 18:552-562.
105. Ostberg, J. R., Kabingu, E., Repasky, E. A. (2003). Thermal regulation of dendritic cell activation and migration from skin explants. Int. J. Hypertherm. 19:520-533.
106. Pardi, R., Inverardi, L., Rugarli, C., Bender, J. R. (1992). Antigen-receptor complex stimulation triggers protein kinase C-dependent CD11a/CD18-cytoskeleton association in T lymphocytes. J. Cell Biol. 116:1211-1220.
107. Pavalko, F. M., LaRoche, S. M. (1993). Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin. J. Immunol. 151:3795-3807.
108. Pavalko, F. M., Walker, D. M., Graham, L., Goheen, M., Doerschuk, C. M., Kansas, G. S. (1995). The cytoplasmic domain of L-selectin interacts with cytoskeletal proteins via alpha-actinin: receptor positioning in microvilli does not require interaction with alpha-actinin. J. Cell Biol. 129:1155-1164.
109. Pittman, Q. J., Veale, W. L., Cockeram, A. W., Cooper, K. E. (1976). Changes in body temperature produced by prostaglandins and pyrogens in the chicken. Am. J. Physiol. 230:1284-1287.
110. Pober, J. S. (2002). Endothelial activation: intracellular signaling pathways. Arthritis Res. 4 (Suppl. 3):S109-S116.
111. Pritchard, M. T., Ostberg, J. R., Evans, S. S., Burd, R., Kraybill, W., Bull, J. M., Repasky, E. A. (2004). Protocols for simulating the thermal component of fever: preclinical and clinical experience. Methods 32:54-62.
112. Reisz, R. R., Muller, J. (2004). Molecular timescales and the fossil record: a paleontological perspective. Trends Genet. 20:237-241.
113. Reynolds, W. W. (1977). Fever and antipyresis in the bluegill sunfish, Lepomis macrochirus. Comp. Biochem. Physiol., C 57:165-167.
114. Roberts, N. J. Jr. (1991). Impact of temperature elevation on immunologic defenses. Rev. Infect. Dis. 13:462-472.
115. Roberts, N. J. Jr., Sandberg, K. (1979). Hyperthermia and human leukocyte function. II. Enhanced production of and response to leukocyte migration inhibition factor (LIF). J. Immunol. 122:1990-1993.
116. Romano, M., Sironi, M., Toniatti, C., Polentarutti, N., Fruscella, P., Ghezzi, P., Faggioni, R., Luini, W., van Hinsbergh, V., Sozzani, S., Bussolino, F., Poli, V., Ciliberto, G., Mantovani, A. (1997). Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment. Immunity 6:315-325.
117. Rose-John, S., Neurath, M. F. (2004). IL-6 trans-signaling: the heat is on. Immunity 20:2-4.
118. Rosen, S. D. (2004). Ligands for L-selectin: homing, inflammation, and beyond. Annu. Rev. Immunol. c22:129-156.
119. Schumacker, P. T., Rowland, J., Saltz, S., Nelson, D. P., Wood, L. D. (1987). Effects of hyperthermia and hypothermia on oxygen extraction by tissues during hypovolemia. J. Appl. Physiol. 63:1246-1252.
120. Shah, A., Unger, E., Bain, M. D., Bruce, R., Bodkin, J., Ginnetti, J., Wang, W. C., Seon, B., Stewart, C. C., Evans, S. S. (2002). Cytokine and adhesion molecule expression in primary human endothelial cells stimulated with fever-range hyperthermia. Int. J. Hypertherm. 18:534-551.
121. Singh, I. S., Viscardi, R. M., Kalvakolanu, I., Calderwood, S., Hasday, J. D. (2000). Inhibition of tumor necrosis factor-alpha transcription in macrophages exposed to febrile range temperature. A possible role for heat shock factor-1 as a negative transcriptional regulator. J. Biol. Chem. 275:9841-9848.
122. Singh, I. S., He, J. R., Calderwood, S., Hasday, J. D. (2002). A high affinity HSF-1 binding site in the 5′-untranslated region of the murine tumor necrosis factor-alpha gene is a transcriptional represser. J. Biol. Chem. 277:4981-4988.
123. Springer, T. A. (1994). Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76:301-314.
124. Stanley, E. D., Jackson, G. G., Panusarn, C., Rubenis, M., Dirda, V. (1975). Increased virus shedding with aspirin treatment of rhinovirus infection. JAMA 231:1248-1251.
125. Starnes, C. O. (1992). Coley's toxins in perspective. Nature 357:11-12.
126. Steeber, D. A., Engel, P., Miller, A. S., Sheetz, M. P., Tedder, T. F. (1997). Ligation of L-selectin through conserved regions within the lectin domain activates signal transduction pathways and integrin function in human, mouse, and rat leukocytes. J. Immunol. 159:952-963.
127. Swartz, K. R., Liu, F., Sewell, D., Schochet, T., Campbell, I., Sandor, M., Fabry, Z. (2001). Interleukin-6 promotes post-traumatic healing in the central nervous system. Brain Res. 896:86-95.
128. +-exchanger regulatory factor 2 and ezrin. Clin. Exp. Nephrol. 7:260-269.
129. Tedder, T. F., Isaacs, C. M., Ernst, T. J., Demetri, G. D., Adler, D. A., Disteche, C. M. (1989). Isolation and chromosomal localization of cDNAs encoding a novel human lymphocyte cell surface molecule, LAM-1. Homology with the mouse lymphocyte homing receptor and other human adhesion proteins. J. Exp. Med. 170:123-133.
130. Tidswell, M., Pachynski, R., Wu, S. W., Qiu, S. Q., Dunham, E., Cochran, N., Briskin, M. J., Kilshaw, P. J., Lazarovits, A. I., Andrew, D. P., Butcher, E. C., Yednock, T. A., Erle, D. J. (1997). Structure-function analysis of the integrin beta 7 subunit: identification of domains involved in adhesion to MAdCAM-1. J. Immunol. 159:1497-1505.
131. Toyota, N., Strebel, F. R., Stephens, L. C., Matsuda, H., Bull, J. M. (1997). Long-duration, mild whole body hyperthermia with cisplatin: tumour response and kinetics of apoptosis and necrosis in a metastatic rat mammary adenocarcinoma. Int. J. Hypertherm. 13:497-506.
132. van Bruggen, I., Robertson, T. A., Papadimitriou, J. M. (1991). The effect of mild hyperthermia on the morphology and function of murine resident peritoneal macrophages. Exp. Mol. Pathol. 55:119-134.
133. Vaughn, L. K., Bernheim, H. A., Kluger, M. J. (1974). Fever in the lizard Dipsosaurus dorsalis. Nature 252:473-474.
134. Vaughn, L. K., Veale, W. L., Cooper, K. E. (1980). Antipyresis: its effect on mortality rate of bacterially infected rabbits. Brain Res. Bull. 5:69-73.
135. von Andrian, U. H., Mempel, T. R. (2003). Homing and cellular traffic in lymph nodes. Nat. Rev., Immunol. 3:867-878.
136. Wang, W. C., Goldman, L. M., Schleider, D. M., Appenheimer, M. M., Subjeck, J. R., Repasky, E. A., Evans, S. S. (1998). Fever-range hyperthermia enhances L-selectin-dependent adhesion of lymphocytes to vascular endothelium. J. Immunol. 160: 961-969.
137. Wang, X. Y., Ostberg, J. R., Repasky, E. A. (1999). Effect of fever-like whole-body hyperthermia on lymphocyte spectrin distribution, protein kinase C activity, and uropod formation. J. Immunol. 162:3378-3387.
138. Wang, J., Chen, H., Brown, E. J. (2001). L-plastin peptide activation of alpha(v)beta(3)-mediated adhesion requires integrin conformational change and actin filament disassembly. J. Biol. Chem. 276:14474-14481.
139. Weinstein, M. P., Iannini, P. B., Stratton, C. W., Eickhoff, T. C. (1978). Spontaneous bacterial peritonitis. A review of 28 cases with emphasis on improved survival and factors influencing prognosis. Am. J. Med. 64:592-598.
140. Yoshida, M., Westlin, W. F., Wang, N., Ingber, D. E., Rosenzweig, A., Resnick, N., Gimbrone, M. A. Jr. (1996). Leukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeleton. J. Cell Biol. 133:445-455.
141. Yoshioka, A., Miyachi, Y., Imamura, S., Hiraoka, M., Jo, S., Abe, M. (1989). Suppression of contact sensitivity by local hyperthermia treatment due to reduced Langerhans cell population in mice. Br. J. Dermatol. 120:493-501.