Glucagon-like peptide-1 enhances production of insulin in insulin-producing cells derived from mouse embryonic stem cells

Journal of Endocrinology

Volumn 186, Issue 2, 2005, Pages 343-352

  Bai, L ^a   Meredith, G ^a   Tuch, B E ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; GLUCOSE TRANSPORTER 2; HEPATOCYTE NUCLEAR FACTOR 3; INSULIN; MESSENGER RNA; NEUROGENIC DIFFERENTIATION FACTOR; NICOTINAMIDE; TRANSCRIPTION FACTOR PDX 1;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; GENE EXPRESSION; GENE SEQUENCE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INSULIN RELEASE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

ANIMALS; C-PEPTIDE; CELL DIFFERENTIATION; CELL LINE; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; IMMUNOHISTOCHEMISTRY; INSULIN; MICE; PEPTIDE FRAGMENTS; PEPTIDES; PROTEIN PRECURSORS; RECEPTORS, GLUCAGON; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELLS; VENOMS;

EID: 23844541266     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.1.06078     Document Type: Article

References (22)

1. Abe K, Niwa H, Iwase K, Takiguchi M, Mori M, Abe SI, Abe K & Yamamura KI 1996 Endoderm-specific gene expression in embryonic stem cells differentiated to embryoid bodies. Experimental Cell Research 229 27-34.
2. Abraham EJ, Leech CA, Lin JC, Zulewski H & Habener JF 2002 Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells. Endocrinology 143 3152-3161.
3. Blyszczuk P, Czyz J, Kania G, Wagner M, Roll U, St-Onge L & Wobus AM 2003 Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells. PNAS 100 998-1003.
4. Friedrich G & Soriano P 1991 Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes and Development 5 1513-1523.
5. Gutniak M, Orskov C, Holst JJ, Ahren B & Efendic S 1992 Antidiabetogenic effect of glucagon-like peptide1 (7-36) amide in normal subjects and patients with diabetes mellitus. New England Journal of Medicine 326 1316-1322.
6. Habener JF 2001 Glucagon-like peptide 1 agonist stimulation of β-cell growth and differentiation. Current Opinion in Endocrinology and Diabetes 8 74-81.
7. Hardikar AA, Wang XY, Williams L, Kwok J, Wong R, Yao M & Tuch BE 2002 Functional maturation of fetal porcine beta cells by glucagon-like peptide 1 and cholecystokinin. Endocrinology 143 3505-3514.
8. Hori Y, Rulifson IC, Tsai BC, Heit JJ, Cahoy JD & Kim SK 2002 Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells. PNAS 99 16105-16110.
9. Hui R, Wright C & Perfetti R 2001 Glucagon-like peptide 1 induces differentiation of islet duodenal homeobox-1 positive pancreatic ductal cells into insulin-secretion cells. Diabetes 50 785-796.
10. Karbanova J & Mokry J 2002 Histological and histochemical analysis of embryoid bodies. Acta Histochemica 104 361-365.
11. Lumelsky N, Blondel O, Laeng P, Velasco I, Ravin R & Mckay R 2001 Differentiation of embryonic stem cells to insulin-secreting structure similar to pancreatic islets. Science 292 1389-1394.
12. Nagy A, Rossant J, Nagy R, Abramow-Newerly W & Roder JC 1993 Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. PNAS 90 8424-8428.
13. Perez-Villamil B, Schwarz PT & Vallejo M 1999 The pancreatic homeodomain transcript factor IDX/IPF1 is expressed in neural cells during brain development. Endocrinology 140 3857-3860.
14. Rajagopal J, Anderson WJ, Kume S, Martinez OI & Melton DA 2003 Insulin staining of ES cell progeny from insulin uptake. Science 299 324.
15. Scrocchi LA, Marshall BA, Cook SM, Brubaker PL & Drucker DJ 1998 Identification of glucagon-like peptide 1 (GLP-1) actions essential for glucose homeostasis in mice with disruption of GLP-1 receptor signalling. Diabetes 47 632-639.
16. Sipione S, Eshpeter A, Lyon J, Korbutt G & Bleackley R 2004 Insulin expression cells From differentiated embryonic stem cells are not beta cells. Diabetologia 47 499-508.
17. Sommer L, Ma Q & Anderson DJ 1996 Neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS. Molecular and Cellular Neurosciences 8 221-241.
18. Soria B, Roche E, Berna G, Leon-Quinto T, Reig JA & Matin F 2000 Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice. Diabetes 49 157-162.
19. Stoffers DA, Kieffer TJ, Hussain MA, Drucker DJ, Bonner-Weir S, Habener JF & Egan JM 2000 Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas. Diabetes 49 741-748.
20. Tuch BE, Turtle JR & Simeonovic CJ 1989 Streptozotocin is not toxic to the human fetal beta cell. Diabetologia 32 678-684.
21. Xu G, Stoffers DA, Habener JF & Bonner-Weir S 1999 Exendin-4 stimulates both β-cell replication and neogenesis, resulting in increased β-cell mass and improved glucose tolerance in diabetic rats. Diabetes 48 2270-2276.
22. Zhou J, Wang Y, Pineyro MA & Egan JM 1999 Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells. Diabetes 48 2358-2366.