On the antimicrobial and hemolytic activities of amphiphilic β-peptides

ChemBioChem

Volumn 2, Issue 10, 2001, Pages 771-773

  Arvidsson, Per I ^a,b,c   Frackenpohl, Jens ^a,b,c   Ryder, Neil S ^a,b,c   Liechty, Brigitta ^a,b,c   Petersen, Frank ^a,b,c   Zimmermann, Heidrun ^a,b,c   Camenisch, Gian P ^a,b,c   Woessner, Ralph ^a,b,c   Seebach, Dieter ^a,b,c  

^a ETH ZURICH   (Switzerland)

^b Novartis Research Institute   (Austria)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Amphiphiles; Antibiotics; Antifungal agents; Helical structures; Peptides

Indexed keywords

ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; PEPTIDE; SURFACTANT;

ARTICLE; CHEMISTRY; DRUG EFFECT; ERYTHROCYTE; HEMOLYSIS; HUMAN; IC 50; MICROBIOLOGICAL EXAMINATION; PROTEIN TERTIARY STRUCTURE; SENSITIVITY AND SPECIFICITY;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; ERYTHROCYTES; HEMOLYSIS; HUMANS; INHIBITORY CONCENTRATION 50; MICROBIAL SENSITIVITY TESTS; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; SENSITIVITY AND SPECIFICITY; SURFACE-ACTIVE AGENTS;

EID: 0035496146     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/1439-7633(20011001)2:10<771::aid-cbic771>3.0.co;2-%23     Document Type: Article

References (7)

1. a) S. Abele, G. Guichard, D. Seebach, Helv. Chim. Acta 1998, 81, 2141;
2. b) P. I. Arvidsson, J. Frackenpohl, D. Seebach, unpublished results.
3. M. Werder, H. Hauser, S. Abele, D. Seebach, Helv. Chim. Acta 1999, 82, 1774.
4. a) H. G. Boman, Annu. Rev. Immunol. 1995, 13, 61;
5. b) A. Tossi, L. Sandri, A. Giangaspero, Biopolymers 2000, 55, 4.
6. Y. Hamuro, J. P. Schneider, W. F. DeGrado, J. Am. Chem. Soc. 1999, 121, 12200;
7. published while the present paper was in print: D. Liu, W. F. DeGrado, J. Am. Chem. Soc. 2001, 123, 7553.