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Volumn 79, Issue 17, 2005, Pages 11239-11246

Functional constraints of influenza A virus epitopes limit escape from cytotoxic T lymphocytes

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; EPITOPE; HLA A ANTIGEN; MATRIX PROTEIN; NUCLEOPROTEIN;

EID: 23844520881     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.17.11239-11246.2005     Document Type: Article
Times cited : (86)

References (60)
  • 1
    • 0026317416 scopus 로고
    • The minimum peptide epitope from the influenza virus matrix protein. Extra and intracellular loading of HLA-A2
    • Bednarek, M. A., S. Y. Sauma, M. C. Gammon, G. Porter, S. Tamhankar, A. R. Williamson, and H. J. Zweerink. 1991. The minimum peptide epitope from the influenza virus matrix protein. Extra and intracellular loading of HLA-A2. J. Immunol. 147:4047-4053.
    • (1991) J. Immunol. , vol.147 , pp. 4047-4053
    • Bednarek, M.A.1    Sauma, S.Y.2    Gammon, M.C.3    Porter, G.4    Tamhankar, S.5    Williamson, A.R.6    Zweerink, H.J.7
  • 3
    • 0036138764 scopus 로고    scopus 로고
    • The magnitude and specificity of influenza A virus-specific cytotoxic T-lymphocyte responses in humans is related to HLA-A and -B phenotype
    • Boon, A. C., G. de Mutsert, Y. M. Graus, R. A. Fouchier, K. Sintnicolaas, A. D. M. E. Osterhaus, and G. F. Rimmelzwaan. 2002. The magnitude and specificity of influenza A virus-specific cytotoxic T-lymphocyte responses in humans is related to HLA-A and -B phenotype. J. Virol. 76:582-590.
    • (2002) J. Virol. , vol.76 , pp. 582-590
    • Boon, A.C.1    De Mutsert, G.2    Graus, Y.M.3    Fouchier, R.A.4    Sintnicolaas, K.5    Osterhaus, A.D.M.E.6    Rimmelzwaan, G.F.7
  • 4
    • 0036168233 scopus 로고    scopus 로고
    • Sequence variation in a newly identified HLA-B35-restricted epitope in the influenza a virus nucleoprotein associated with escape from cytotoxic T lymphocytes
    • Boon, A. C. M., G. de Mutsert, Y. M. F. Graus, R. A. M. Fouchier, K. Sintnicolaas, A. D. M. E. Osterhaus, and G. F. Rimmelzwaan. 2002. Sequence variation in a newly identified HLA-B35-restricted epitope in the influenza A virus nucleoprotein associated with escape from cytotoxic T lymphocytes. J. Virol. 76:2567-2572.
    • (2002) J. Virol. , vol.76 , pp. 2567-2572
    • Boon, A.C.M.1    De Mutsert, G.2    Graus, Y.M.F.3    Fouchier, R.A.M.4    Sintnicolaas, K.5    Osterhaus, A.D.M.E.6    Rimmelzwaan, G.F.7
  • 7
    • 16944365445 scopus 로고    scopus 로고
    • Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus
    • Borrow, P., H. Lewicki, X. Wei, M. S. Horwitz, N. Peffer, H. Meyers, J. A. Nelson, J. E. Gairin, B. H. Hahn, M. B. Oldstone, and G. M. Shaw. 1997. Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus. Nat. Med. 3:205-211.
    • (1997) Nat. Med. , vol.3 , pp. 205-211
    • Borrow, P.1    Lewicki, H.2    Wei, X.3    Horwitz, M.S.4    Peffer, N.5    Meyers, H.6    Nelson, J.A.7    Gairin, J.E.8    Hahn, B.H.9    Oldstone, M.B.10    Shaw, G.M.11
  • 8
    • 11144244386 scopus 로고    scopus 로고
    • Influenza A viruses with mutations in the m1 helix six domain display a wide variety of morphological phenotypes
    • Burleigh, L. M., L. J. Calder, J. J. Skehel, and D. A. Steinhauer. 2005. Influenza A viruses with mutations in the m1 helix six domain display a wide variety of morphological phenotypes. J. Virol. 79:1262-1270.
    • (2005) J. Virol. , vol.79 , pp. 1262-1270
    • Burleigh, L.M.1    Calder, L.J.2    Skehel, J.J.3    Steinhauer, D.A.4
  • 9
    • 0030671121 scopus 로고    scopus 로고
    • Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus
    • Chang, K. M., B. Rehermann, J. G. McHutchison, C. Pasquinelli, S. Southwood, A. Sette, and F. V. Chisari. 1997. Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus. J. Clin. Investig. 100:2376-2385.
    • (1997) J. Clin. Investig. , vol.100 , pp. 2376-2385
    • Chang, K.M.1    Rehermann, B.2    McHutchison, J.G.3    Pasquinelli, C.4    Southwood, S.5    Sette, A.6    Chisari, F.V.7
  • 10
    • 0034644009 scopus 로고    scopus 로고
    • The immune system. Second of two parts
    • Delves, P. J., and I. M. Roitt. 2000. The immune system. Second of two parts. N. Engl. J. Med. 343:108-117.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 108-117
    • Delves, P.J.1    Roitt, I.M.2
  • 13
    • 0029073532 scopus 로고
    • Identification of the peptide binding motif for HLA-B44, one of the most common HLA-B alleles in the Caucasian population
    • DiBrino, M., K. C. Parker, D. H. Margulies, J. Shiloach, R. V. Turner, W. E. Biddison, and J. E. Coligan. 1995. Identification of the peptide binding motif for HLA-B44, one of the most common HLA-B alleles in the Caucasian population. Biochemistry 34:10130-10138.
    • (1995) Biochemistry , vol.34 , pp. 10130-10138
    • DiBrino, M.1    Parker, K.C.2    Margulies, D.H.3    Shiloach, J.4    Turner, R.V.5    Biddison, W.E.6    Coligan, J.E.7
  • 14
    • 0027370597 scopus 로고
    • HLA-A1 and HLA-A3 T cell epitopes derived from influenza virus proteins predicted from peptide binding motifs
    • DiBrino, M., T. Tsuchida, R. V. Turner, K. C. Parker, J. E. Coligan, and W. E. Biddison. 1993. HLA-A1 and HLA-A3 T cell epitopes derived from influenza virus proteins predicted from peptide binding motifs. J. Immunol. 151:5930-5935.
    • (1993) J. Immunol. , vol.151 , pp. 5930-5935
    • Dibrino, M.1    Tsuchida, T.2    Turner, R.V.3    Parker, K.C.4    Coligan, J.E.5    Biddison, W.E.6
  • 18
    • 0034087707 scopus 로고    scopus 로고
    • Human memory CTL response specific for influenza A virus is broad and multispecific
    • Gianfrani, C., C. Oseroff, J. Sidney, R. W. Chesnut, and A. Sette. 2000. Human memory CTL response specific for influenza A virus is broad and multispecific. Hum. Immunol. 61:438-452.
    • (2000) Hum. Immunol. , vol.61 , pp. 438-452
    • Gianfrani, C.1    Oseroff, C.2    Sidney, J.3    Chesnut, R.W.4    Sette, A.5
  • 19
    • 0141702339 scopus 로고    scopus 로고
    • Population dynamics of rapid fixation in cytotoxic T lymphocyte escape mutants of influenza A
    • Gog, J. R., G. F. Rimmelzwaan, A. D. Osterhaus, and B. T. Grenfell. 2003. Population dynamics of rapid fixation in cytotoxic T lymphocyte escape mutants of influenza A. Proc. Natl. Acad. Sci. USA 100:11143-11147.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 11143-11147
    • Gog, J.R.1    Rimmelzwaan, G.F.2    Osterhaus, A.D.3    Grenfell, B.T.4
  • 20
    • 0024246812 scopus 로고
    • Recognition of influenza a matrix protein by HLA-A2-restricted cytotoxic T lymphocytes. Use of analogues to orientate the matrix peptide in the HLA-A2 binding site
    • Gotch, F., A. McMichael, and J. Rothbard. 1988. Recognition of influenza A matrix protein by HLA-A2-restricted cytotoxic T lymphocytes. Use of analogues to orientate the matrix peptide in the HLA-A2 binding site. J. Exp. Med. 168:2045-2057.
    • (1988) J. Exp. Med. , vol.168 , pp. 2045-2057
    • Gotch, F.1    McMichael, A.2    Rothbard, J.3
  • 24
  • 25
    • 0033564710 scopus 로고    scopus 로고
    • Human CD8+ and CD4+ T lymphocyte memory to influenza a viruses of swine and avian species
    • Jameson, J., J. Cruz, M. Terajima, and F. A. Ennis. 1999. Human CD8+ and CD4+ T lymphocyte memory to influenza A viruses of swine and avian species. J. Immunol. 162:7578-7583.
    • (1999) J. Immunol. , vol.162 , pp. 7578-7583
    • Jameson, J.1    Cruz, J.2    Terajima, M.3    Ennis, F.A.4
  • 27
    • 0002222774 scopus 로고    scopus 로고
    • Computational analysis of HIV molecular sequences
    • A. G. Rodrigo and G. H. Learn (ed.) . Kluwer Academic Publishers, Dordrecht, The Netherlands
    • Korber, B. 2000. Computational analysis of HIV molecular sequences, p. 55-72. In A. G. Rodrigo and G. H. Learn (ed.), HIV signature and sequence variation analysis. Kluwer Academic Publishers, Dordrecht, The Netherlands.
    • (2000) HIV Signature and Sequence Variation Analysis , pp. 55-72
    • Korber, B.1
  • 28
    • 0028145416 scopus 로고
    • Virus escape from CTL recognition
    • Koup, R. A. 1994. Virus escape from CTL recognition. J. Exp. Med. 180:779-782.
    • (1994) J. Exp. Med. , vol.180 , pp. 779-782
    • Koup, R.A.1
  • 29
    • 0028909051 scopus 로고
    • Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of influenza A is dominated by T cells bearing the V beta 17 gene segment
    • Lehner, P. J., E. C. Wang, P. A. Moss, S. Williams, K. Platt, S. M. Friedman, J. I. Bell, and L. K. Borysiewicz. 1995. Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of influenza A is dominated by T cells bearing the V beta 17 gene segment. J. Exp. Med. 181:79-91.
    • (1995) J. Exp. Med. , vol.181 , pp. 79-91
    • Lehner, P.J.1    Wang, E.C.2    Moss, P.A.3    Williams, S.4    Platt, K.5    Friedman, S.M.6    Bell, J.I.7    Borysiewicz, L.K.8
  • 30
    • 4544279879 scopus 로고    scopus 로고
    • Genetic analysis of human H2N2 and early H3N2 influenza viruses, 1957-1972: Evidence for genetic divergence and multiple reassortment events
    • Lindstrom, S. E., N. J. Cox, and A. Klimov. 2004. Genetic analysis of human H2N2 and early H3N2 influenza viruses, 1957-1972: evidence for genetic divergence and multiple reassortment events. Virology 328:101-119.
    • (2004) Virology , vol.328 , pp. 101-119
    • Lindstrom, S.E.1    Cox, N.J.2    Klimov, A.3
  • 31
    • 13744253459 scopus 로고    scopus 로고
    • Attenuating mutations of the matrix gene of influenza A/WSN/33 virus
    • Liu, T., and Z. Ye. 2005. Attenuating mutations of the matrix gene of influenza A/WSN/33 virus. J. Virol. 79:1918-1923.
    • (2005) J. Virol. , vol.79 , pp. 1918-1923
    • Liu, T.1    Ye, Z.2
  • 32
    • 34447622953 scopus 로고    scopus 로고
    • The value of a database in surveillance and vaccine selection
    • A. D. M. E. Osterhaus, N. Cox, and A. W. Hampson (ed.) . Elsevier Science, Amsterdam, The Netherlands
    • Macken, C., H. Lu, J. Goodman, and L. Boykin. 2001. The value of a database in surveillance and vaccine selection, p. 103-106. In A. D. M. E. Osterhaus, N. Cox, and A. W. Hampson (ed.), Options for the control of influenza IV. Elsevier Science, Amsterdam, The Netherlands.
    • (2001) Options for the Control of Influenza IV , pp. 103-106
    • Macken, C.1    Lu, H.2    Goodman, J.3    Boykin, L.4
  • 35
    • 0030891167 scopus 로고    scopus 로고
    • Escape of human immunodeficiency virus from immune control
    • McMichael, A. J., and R. E. Phillips. 1997. Escape of human immunodeficiency virus from immune control. Annu. Rev. Immunol. 15:271-296.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 271-296
    • McMichael, A.J.1    Phillips, R.E.2
  • 36
    • 0028930288 scopus 로고
    • Immunobiology of cytotoxic T-cell escape mutants of lymphocytic choriomeningitis virus
    • Moskophidis, D., and R. M. Zinkernagel. 1995. Immunobiology of cytotoxic T-cell escape mutants of lymphocytic choriomeningitis virus. J. Virol. 69:2187-2193.
    • (1995) J. Virol. , vol.69 , pp. 2187-2193
    • Moskophidis, D.1    Zinkernagel, R.M.2
  • 37
    • 0025992233 scopus 로고
    • Extensive conservation of alpha and beta chains of the human T-cell antigen receptor recognizing HLA-A2 and influenza a matrix peptide
    • Moss, P. A., R. J. Moots, W. M. Rosenberg, S. J. Rowland-Jones, H. C. Bodmer, A. J. McMichael, and J. I. Bell. 1991. Extensive conservation of alpha and beta chains of the human T-cell antigen receptor recognizing HLA-A2 and influenza A matrix peptide. Proc. Natl. Acad. Sci. USA 88:8987-8990.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8987-8990
    • Moss, P.A.1    Moots, R.J.2    Rosenberg, W.M.3    Rowland-Jones, S.J.4    Bodmer, H.C.5    McMichael, A.J.6    Bell, J.I.7
  • 38
    • 0022507362 scopus 로고
    • Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions
    • Nei, M., and T. Gojobori. 1986. Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. Mol. Biol. Evol. 3:418-426.
    • (1986) Mol. Biol. Evol. , vol.3 , pp. 418-426
    • Nei, M.1    Gojobori, T.2
  • 39
    • 0030876638 scopus 로고    scopus 로고
    • How viruses escape from cytotoxic T lymphocytes: Molecular parameters and players
    • Oldstone, M. B. 1997. How viruses escape from cytotoxic T lymphocytes: molecular parameters and players. Virology 234:179-185.
    • (1997) Virology , vol.234 , pp. 179-185
    • Oldstone, M.B.1
  • 40
    • 0028286120 scopus 로고
    • Variance and covariances of the numbers of synonymous and nonsynonymous substitutions per site
    • Ota, T., and M. Nei. 1994. Variance and covariances of the numbers of synonymous and nonsynonymous substitutions per site. Mol. Biol. Evol. 11:613-619.
    • (1994) Mol. Biol. Evol. , vol.11 , pp. 613-619
    • Ota, T.1    Nei, M.2
  • 42
    • 0242409395 scopus 로고    scopus 로고
    • Simian-human immunodeficiency virus escape from cytotoxic T-lymphocyte recognition at a structurally constrained epitope
    • Peyerl, F. W., D. H. Barouch, W. W. Yeh, H. S. Bazick, J. Kunstman, K. J. Kunstman, S. M. Wolinsky, and N. L. Letvin. 2003. Simian-human immunodeficiency virus escape from cytotoxic T-lymphocyte recognition at a structurally constrained epitope. J. Virol. 77:12572-12578.
    • (2003) J. Virol. , vol.77 , pp. 12572-12578
    • Peyerl, F.W.1    Barouch, D.H.2    Yeh, W.W.3    Bazick, H.S.4    Kunstman, J.5    Kunstman, K.J.6    Wolinsky, S.M.7    Letvin, N.L.8
  • 43
    • 10044227534 scopus 로고    scopus 로고
    • Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope
    • Peyerl, F. W., H. S. Bazick, M. H. Newberg, D. H. Barouch, J. Sodroski, and N. L. Letvin. 2004. Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope. J. Virol. 78:13901-13910.
    • (2004) J. Virol. , vol.78 , pp. 13901-13910
    • Peyerl, F.W.1    Bazick, H.S.2    Newberg, M.H.3    Barouch, D.H.4    Sodroski, J.5    Letvin, N.L.6
  • 45
    • 6344249131 scopus 로고    scopus 로고
    • Between-host evolution of cytotoxic T-lymphocyte epitopes in human immunodeficiency virus type 1: An approach based on phylogenetically independent comparisons
    • Piontkivska, H., and A. L. Hughes. 2004. Between-host evolution of cytotoxic T-lymphocyte epitopes in human immunodeficiency virus type 1: an approach based on phylogenetically independent comparisons. J. Virol. 78:11758-11765.
    • (2004) J. Virol. , vol.78 , pp. 11758-11765
    • Piontkivska, H.1    Hughes, A.L.2
  • 48
    • 0031659446 scopus 로고    scopus 로고
    • The influence of antigenic variation on cytotoxic T lymphocyte responses in HIV-1 infection
    • Price, D. A., U. C. Meier, P. Klenerman, M. A. Purbhoo, R. E. Phillips, and A. K. Sewell. 1998. The influence of antigenic variation on cytotoxic T lymphocyte responses in HIV-1 infection. J. Mol. Med. 76:699-708.
    • (1998) J. Mol. Med. , vol.76 , pp. 699-708
    • Price, D.A.1    Meier, U.C.2    Klenerman, P.3    Purbhoo, M.A.4    Phillips, R.E.5    Sewell, A.K.6
  • 49
    • 0031866073 scopus 로고    scopus 로고
    • Comparison of RNA hybridization, hemagglutination assay, titration of infectious virus and immunofluorescence as methods for monitoring influenza virus replication in vitro
    • Rimmelzwaan, G. F., M. Baars, E. C. Claas, and A. D. Osterhaus. 1998. Comparison of RNA hybridization, hemagglutination assay, titration of infectious virus and immunofluorescence as methods for monitoring influenza virus replication in vitro. J. Virol. Methods 74:57-66.
    • (1998) J. Virol. Methods , vol.74 , pp. 57-66
    • Rimmelzwaan, G.F.1    Baars, M.2    Claas, E.C.3    Osterhaus, A.D.4
  • 50
    • 3543128220 scopus 로고    scopus 로고
    • Functional compensation of a detrimental amino acid substitution in a cytotoxic-T-lymphocyte epitope of influenza a viruses by comutations
    • Rimmelzwaan, G. F., E. G. M. Berkhoff, N. J. Nieuwkoop, R. A. M. Fouchier, and A. D. M. E. Osterhaus. 2004. Functional compensation of a detrimental amino acid substitution in a cytotoxic-T-lymphocyte epitope of influenza A viruses by comutations. J. Virol. 78:8946-8949.
    • (2004) J. Virol. , vol.78 , pp. 8946-8949
    • Rimmelzwaan, G.F.1    Berkhoff, E.G.M.2    Nieuwkoop, N.J.3    Fouchier, R.A.M.4    Osterhaus, A.D.M.E.5
  • 51
    • 2442519025 scopus 로고    scopus 로고
    • Sequence variation in ihe influenza a virus nucleoprotein associated with escape from cytotoxic T lymphocytes
    • Rimmelzwaan, G. F., A. C. Boon, J. T. Voeten, E. G. Berkhoff, R. A. Fouchier, and A. D. Osterhaus. 2004. Sequence variation in ihe influenza A virus nucleoprotein associated with escape from cytotoxic T lymphocytes. Virus Res. 103:97-100.
    • (2004) Virus Res. , vol.103 , pp. 97-100
    • Rimmelzwaan, G.F.1    Boon, A.C.2    Voeten, J.T.3    Berkhoff, E.G.4    Fouchier, R.A.5    Osterhaus, A.D.6
  • 52
    • 20044369940 scopus 로고    scopus 로고
    • Full restoration of viral fitness by multiple compensatory comutations in the nucleoprotein of influenza A virus cytotoxic T lymphocyte escape mutants
    • Rimmelzwaan, G. F., E. G. Berkhoff, N. J. Nieuwkoop, D. J. Smith, R. A. Fouchier, and A. D. Osterhaus, 2005. Full restoration of viral fitness by multiple compensatory comutations in the nucleoprotein of influenza A virus cytotoxic T lymphocyte escape mutants. J. Gen. Virol. 86:1801-1805.
    • (2005) J. Gen. Virol. , vol.86 , pp. 1801-1805
    • Rimmelzwaan, G.F.1    Berkhoff, E.G.2    Nieuwkoop, N.J.3    Smith, D.J.4    Fouchier, R.A.5    Osterhaus, A.D.6
  • 53
    • 0034623979 scopus 로고    scopus 로고
    • A randomized, double blind study in young healthy adults comparing cell mediated and humoral immune responses induced by influenza ISCOM vaccines and conventional vaccines
    • Rimmelzwaan, G. F., N. Nieuwkoop, A. Brandenburg, G. Sutter, W. E. Beyer, D. Maher, J. Bates, and A. D. Osterhaus. 2000. A randomized, double blind study in young healthy adults comparing cell mediated and humoral immune responses induced by influenza ISCOM vaccines and conventional vaccines. Vaccine 19:1180-1187.
    • (2000) Vaccine , vol.19 , pp. 1180-1187
    • Rimmelzwaan, G.F.1    Nieuwkoop, N.2    Brandenburg, A.3    Sutter, G.4    Beyer, W.E.5    Maher, D.6    Bates, J.7    Osterhaus, A.D.8
  • 54
    • 0038281510 scopus 로고    scopus 로고
    • HLA-B*0702 transgenic, H-2KbDb double-knockout mice: Phenotypical and functional characterization in response to influenza virus
    • Rohrlich, P. S., S. Cardinaud, H. Firat, M. Lamari, P. Briand, N. Escriou, and F. A. Lemonnier. 2003. HLA-B*0702 transgenic, H-2KbDb double-knockout mice: phenotypical and functional characterization in response to influenza virus. Int. Immunol. 15:765-772.
    • (2003) Int. Immunol. , vol.15 , pp. 765-772
    • Rohrlich, P.S.1    Cardinaud, S.2    Firat, H.3    Lamari, M.4    Briand, P.5    Escriou, N.6    Lemonnier, F.A.7
  • 57
    • 0022483534 scopus 로고
    • The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides
    • Townsend, A. R., J. Rothbard, F. M. Gotch, G. Bahadur, D. Wraith, and A. J. McMichael. 1986. The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. Cell 44:959-968.
    • (1986) Cell , vol.44 , pp. 959-968
    • Townsend, A.R.1    Rothbard, J.2    Gotch, F.M.3    Bahadur, G.4    Wraith, D.5    McMichael, A.J.6
  • 58
    • 0033928393 scopus 로고    scopus 로고
    • Antigenic drift in the influenza a virus (H3N2) nucleoprotein and escape from recognition by cytotoxic T lymphocytes
    • Voeten, J. T. M., T. M. Bestebroer, N. J. Nieuwkoop, R. A. M. Fouchier, A. D. M. E. Osterhaus, and G. F. Rimmelzwaan. 2000. Antigenic drift in the influenza A virus (H3N2) nucleoprotein and escape from recognition by cytotoxic T lymphocytes. J. Virol. 74:6800-6807.
    • (2000) J. Virol. , vol.74 , pp. 6800-6807
    • Voeten, J.T.M.1    Bestebroer, T.M.2    Nieuwkoop, N.J.3    Fouchier, R.A.M.4    Osterhaus, A.D.M.E.5    Rimmelzwaan, G.F.6
  • 59
    • 0035163814 scopus 로고    scopus 로고
    • Cross-reactivity between hepatitis C virus and influenza A virus determinant-specific cytotoxic T cells
    • Wedemeyer, H., E. Mizukoshi, A. R. Davis, J. R. Bennink, and B. Rehermann. 2001. Cross-reactivity between hepatitis C virus and influenza A virus determinant-specific cytotoxic T cells. J. Virol. 75:11392-11400.
    • (2001) J. Virol. , vol.75 , pp. 11392-11400
    • Wedemeyer, H.1    Mizukoshi, E.2    Davis, A.R.3    Bennink, J.R.4    Rehermann, B.5


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