-
1
-
-
0023950743
-
Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors
-
Nagel, J. E., Chopra, R. K., Chrest, F. J. et al. 1988. Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors. J. Clin. Invest. 81:1096.
-
(1988)
J. Clin. Invest.
, vol.81
, pp. 1096
-
-
Nagel, J.E.1
Chopra, R.K.2
Chrest, F.J.3
-
2
-
-
0019402106
-
Lymphokines and aging: Interleukin-2 production and activity in aged animals
-
Thoman, M. L. and Weigle, W. O. 1981. Lymphokines and aging: interleukin-2 production and activity in aged animals. J. Immunol. 127:2102.
-
(1981)
J. Immunol.
, vol.127
, pp. 2102
-
-
Thoman, M.L.1
Weigle, W.O.2
-
3
-
-
0037087066
-
Infective endocarditis in elderly patients
-
Dhawan, V. K. 2002. Infective endocarditis in elderly patients. Clin. Infect. Dis. 34:806.
-
(2002)
Clin. Infect. Dis.
, vol.34
, pp. 806
-
-
Dhawan, V.K.1
-
4
-
-
0032923446
-
Pneumonia in the elderly: Overview of diagnostic and therapeutic approaches
-
Fein, A. M. 1999. Pneumonia in the elderly: Overview of diagnostic and therapeutic approaches. Clin. Infect. Dis. 28:726.
-
(1999)
Clin. Infect. Dis.
, vol.28
, pp. 726
-
-
Fein, A.M.1
-
5
-
-
0037331789
-
Problems and solutions to the development of vaccines in the elderly
-
Effros, R. B. 2003. Problems and solutions to the development of vaccines in the elderly. Immunol. Allergy Clin. North Am. 23:41.
-
(2003)
Immunol. Allergy Clin. North Am.
, vol.23
, pp. 41
-
-
Effros, R.B.1
-
6
-
-
0037325417
-
Aging, immunity, and tumor susceptibility
-
Zhang, H. and Grizzle, W. E. 2003. Aging, immunity, and tumor susceptibility. Immunol. Allergy Clin. North Am. 23:83.
-
(2003)
Immunol. Allergy Clin. North Am.
, vol.23
, pp. 83
-
-
Zhang, H.1
Grizzle, W.E.2
-
7
-
-
0023199559
-
Diminished calcium influx in lectin-stimulated T cells from old mice
-
Miller,R. A., Jacobson, B. and Simons, E.R. 1987. Diminished calcium influx in lectin-stimulated T cells from old mice. J. Cell. Physiol. 132:337.
-
(1987)
J. Cell. Physiol.
, vol.132
, pp. 337
-
-
Miller, R.A.1
Jacobson, B.2
Simons, E.R.3
-
8
-
-
0029988530
-
Age-related reductions in the activation of mitogen-activated protein kinases p44mapk/ERK1 and p42mapk/ERK2 in human T cells stimulated via ligation of the T cell receptor complex
-
Whisler, R. L., Newhouse, Y. G. and Bagenstose, S. E. 1996. Age-related reductions in the activation of mitogen-activated protein kinases p44mapk/ERK1 and p42mapk/ERK2 in human T cells stimulated via ligation of the T cell receptor complex. Cell. Immunol. 168:201.
-
(1996)
Cell. Immunol.
, vol.168
, pp. 201
-
-
Whisler, R.L.1
Newhouse, Y.G.2
Bagenstose, S.E.3
-
9
-
-
0033226805
-
Age-related decline in activation of JNK by TCR- and CD28-mediated signals in murine T-lymphocytes
-
Kirk, C. J., Freilich, A. M. and Miller, R. A. 1999. Age-related decline in activation of JNK by TCR- and CD28-mediated signals in murine T-lymphocytes. Cell. Immunol. 197:75.
-
(1999)
Cell. Immunol.
, vol.197
, pp. 75
-
-
Kirk, C.J.1
Freilich, A.M.2
Miller, R.A.3
-
10
-
-
0022574519
-
The effect of aging on the expression of interleukin 2 messenger ribonucleic acid
-
Wu, W., Pahlavani, M., Cheung, H. T. and Richardson, A. 1986. The effect of aging on the expression of interleukin 2 messenger ribonucleic acid. Cell. Immunol. 100:224.
-
(1986)
Cell. Immunol.
, vol.100
, pp. 224
-
-
Wu, W.1
Pahlavani, M.2
Cheung, H.T.3
Richardson, A.4
-
11
-
-
0024511525
-
Stimulation of murine T cell subsets with anti-CD3 antibody. Age-related defects in the expression of early activation molecules
-
Ernst, D. N., Weigle, W. O., McQuitty, D. N., Rothermel, A. L. and Hobbs, M. V. 1989. Stimulation of murine T cell subsets with anti-CD3 antibody. Age-related defects in the expression of early activation molecules. J. Immunol. 142:1413.
-
(1989)
J. Immunol.
, vol.142
, pp. 1413
-
-
Ernst, D.N.1
Weigle, W.O.2
McQuitty, D.N.3
Rothermel, A.L.4
Hobbs, M.V.5
-
12
-
-
0034254660
-
Age-dependent alterations in the assembly of signal transduction complexes at the site of T cell/APC interaction
-
Tamir, A., Eisenbraun, M. D., Garcia, G. G. and Miller, R. A. 2000. Age-dependent alterations in the assembly of signal transduction complexes at the site of T cell/APC interaction. J. Immunol. 165:1243.
-
(2000)
J. Immunol.
, vol.165
, pp. 1243
-
-
Tamir, A.1
Eisenbraun, M.D.2
Garcia, G.G.3
Miller, R.A.4
-
13
-
-
0035284902
-
Single-cell analyses reveal two defects in peptide-specific activation of naive T cells from aged mice
-
Garcia, G. G. and Miller, R. A. 2001. Single-cell analyses reveal two defects in peptide-specific activation of naive T cells from aged mice. J. Immunol. 166:3151.
-
(2001)
J. Immunol.
, vol.166
, pp. 3151
-
-
Garcia, G.G.1
Miller, R.A.2
-
14
-
-
0027175441
-
Increased function of P-glycoprotein in T lymphocyte subsets of aging mice
-
Witkowski, J. M. and Miller, R. A. 1993. Increased function of P-glycoprotein in T lymphocyte subsets of aging mice. J. Immunol. 150:1296.
-
(1993)
J. Immunol.
, vol.150
, pp. 1296
-
-
Witkowski, J.M.1
Miller, R.A.2
-
15
-
-
0031922224
-
Regulation of in vitro and in vivo T cell activation by CD43
-
Thurman, E. C., Walker, J., Jayaraman, S., Manjunath, N., Ardman, B. and Green, J. M. 1998. Regulation of in vitro and in vivo T cell activation by CD43. Int. Immunol. 10:691.
-
(1998)
Int. Immunol.
, vol.10
, pp. 691
-
-
Thurman, E.C.1
Walker, J.2
Jayaraman, S.3
Manjunath, N.4
Ardman, B.5
Green, J.M.6
-
16
-
-
0029120438
-
Negative regulation of T-cell adhesion and activation by CD43
-
Manjunath, N., Correa, M., Ardman, M. and Ardman, B. 1995. Negative regulation of T-cell adhesion and activation by CD43. Nature 377:535.
-
(1995)
Nature
, vol.377
, pp. 535
-
-
Manjunath, N.1
Correa, M.2
Ardman, M.3
Ardman, B.4
-
17
-
-
0035905767
-
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
-
Irie-Sasaki, J., Sasaki, T., Matsumoto, W. et al. 2001. CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling. Nature 409:349.
-
(2001)
Nature
, vol.409
, pp. 349
-
-
Irie-Sasaki, J.1
Sasaki, T.2
Matsumoto, W.3
-
18
-
-
0033558102
-
Cutting edge: The CD45 tyrosine phosphatase is an inhibitor of Lck activity in thymocytes
-
D'Oro, U. and Ashwell, J. D. 1999. Cutting edge: The CD45 tyrosine phosphatase is an inhibitor of Lck activity in thymocytes. J. Immunol. 162:1879.
-
(1999)
J. Immunol.
, vol.162
, pp. 1879
-
-
D'Oro, U.1
Ashwell, J.D.2
-
19
-
-
0346121457
-
Age-related defects in CD4+ T cell activation reversed by glycoprotein endopeptidase
-
Garcia, G. G. and Miller, R. A. 2003. Age-related defects in CD4+ T cell activation reversed by glycoprotein endopeptidase. Eur. J. Immunol. 33:3464.
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 3464
-
-
Garcia, G.G.1
Miller, R.A.2
-
20
-
-
0036839168
-
Age-dependent defects in TCR-triggered cytoskeletal rearrangement in CD4+ T Cells
-
Garcia, G. G. and Miller, R. A. 2002. Age-dependent defects in TCR-triggered cytoskeletal rearrangement in CD4+ T Cells. J. Immunol. 169:5021.
-
(2002)
J. Immunol.
, vol.169
, pp. 5021
-
-
Garcia, G.G.1
Miller, R.A.2
-
21
-
-
0031561783
-
Differential tyrosine phosphorylation of zeta chain dimers in mouse CD4 T lymphocytes: Effect of age
-
Garcia, G. G. and Miller, R. A. 1997. Differential tyrosine phosphorylation of zeta chain dimers in mouse CD4 T lymphocytes: Effect of age. Cell. Immunol. 175:51.
-
(1997)
Cell. Immunol.
, vol.175
, pp. 51
-
-
Garcia, G.G.1
Miller, R.A.2
-
22
-
-
0013145302
-
Measurement of intracellular ions by flow cytometry
-
Coligan, J., Kruisbeek, A., Margulies, D., Shevach, E. and Strober, W., eds John Wiley & Sons, New York
-
June, C., Abe, R. and Rabinovitch, P. S. 2003. Measurement of intracellular ions by flow cytometry. In Coligan, J., Kruisbeek, A., Margulies, D., Shevach, E. and Strober, W., eds, Current Protocols in Immunology. John Wiley & Sons, New York.
-
(2003)
Current Protocols in Immunology
-
-
June, C.1
Abe, R.2
Rabinovitch, P.S.3
-
23
-
-
0031449597
-
Early activation defects in T lymphocytes from aged mice
-
Miller, R. A., Garcia, G. G., Kirk, C. J. and Witkowski, J. M. 1997. Early activation defects in T lymphocytes from aged mice. Immunol. Rev. 160:79.
-
(1997)
Immunol. Rev.
, vol.160
, pp. 79
-
-
Miller, R.A.1
Garcia, G.G.2
Kirk, C.J.3
Witkowski, J.M.4
-
24
-
-
0000660645
-
Aging and immune function
-
Paul, W. E., ed., Lippincott-Raven, Philadelphia, PA, USA
-
Miller, R. A. 1999. Aging and immune function. In Paul, W. E., ed., Fundamental Immunology, p. 947. Lippincott-Raven, Philadelphia, PA, USA.
-
(1999)
Fundamental Immunology
, pp. 947
-
-
Miller, R.A.1
-
25
-
-
0017601372
-
The quantitative production of interferon by mitogen-stimulated mouse lymphocytes as a function of age and its effect on the lymphocytes proliferative response
-
Heine, N. and Adler, W. H. 1977. The quantitative production of interferon by mitogen-stimulated mouse lymphocytes as a function of age and its effect on the lymphocytes proliferative response. J. Immunol. 118:1366.
-
(1977)
J. Immunol.
, vol.118
, pp. 1366
-
-
Heine, N.1
Adler, W.H.2
-
26
-
-
0027177864
-
The age-associated increase in IFN-gamma synthesis by mouse CD8+ T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression
-
Ernst, D. N., Weigle, W. O., Noonan, D. J., McQuitty, D. N. and Hobbs, M. V. 1993. The age-associated increase in IFN-gamma synthesis by mouse CD8+ T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression. J. Immunol. 151:575.
-
(1993)
J. Immunol.
, vol.151
, pp. 575
-
-
Ernst, D.N.1
Weigle, W.O.2
Noonan, D.J.3
McQuitty, D.N.4
Hobbs, M.V.5
-
27
-
-
0029925346
-
Cytokine production pathway in the elderly
-
Caruso, C., Candore, G., Cigna, D. et al. 1996. Cytokine production pathway in the elderly. Immunol. Res. 15:84.
-
(1996)
Immunol. Res.
, vol.15
, pp. 84
-
-
Caruso, C.1
Candore, G.2
Cigna, D.3
-
28
-
-
0036137060
-
Differential effects of ageing on cytokine and chemokine responses during type-1 (mycobacterial) and type-2 (schistosomal) pulmonary granulomatous inflammation in mice
-
Chiu, B. C., Shang, X., Frait, K. A. et al. 2002. Differential effects of ageing on cytokine and chemokine responses during type-1 (mycobacterial) and type-2 (schistosomal) pulmonary granulomatous inflammation in mice. Mech. Ageing Dev. 123:313.
-
(2002)
Mech. Ageing Dev.
, vol.123
, pp. 313
-
-
Chiu, B.C.1
Shang, X.2
Frait, K.A.3
-
29
-
-
0025087733
-
Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice
-
Ernst, D. N., Hobbs, M. V., Torbett, B. E. et al. 1990. Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice. J. Immunol. 145:1295.
-
(1990)
J. Immunol.
, vol.145
, pp. 1295
-
-
Ernst, D.N.1
Hobbs, M.V.2
Torbett, B.E.3
-
30
-
-
0034005120
-
Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition
-
van der Merwe, P. A., Davis, S. J., Shaw, A. S. and Dustin, M. L. 2000. Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition. Semin. Immunol. 12:5.
-
(2000)
Semin. Immunol.
, vol.12
, pp. 5
-
-
van der Merwe, P.A.1
Davis, S.J.2
Shaw, A.S.3
Dustin, M.L.4
-
31
-
-
0025861263
-
Cell proliferation and cytokine production by CD4+ cells from old mice
-
Hobbs, M. V., Ernst, D. N., Torbett, B. E. et al. 1991. Cell proliferation and cytokine production by CD4+ cells from old mice. J. Cell. Biochem. 46:312.
-
(1991)
J. Cell. Biochem.
, vol.46
, pp. 312
-
-
Hobbs, M.V.1
Ernst, D.N.2
Torbett, B.E.3
-
32
-
-
14744305644
-
Age-associated changes in glycosylation of CD43 and CD45 on mouse CD4 T cells
-
Garcia, G. G., Berger, S. B., Sadighi Akha, A. A. and Miller, R. A. 2005. Age-associated changes in glycosylation of CD43 and CD45 on mouse CD4 T cells. Eur. J. Immunol. 35:622.
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 622
-
-
Garcia, G.G.1
Berger, S.B.2
Sadighi Akha, A.A.3
Miller, R.A.4
-
33
-
-
0033910513
-
Ganglioside control over IL-4 priming and cytokine production in activated T cells
-
Chen, X. P., Ding, X. and Daynes, R. A. 2000. Ganglioside control over IL-4 priming and cytokine production in activated T cells. Cytokine 12:972.
-
(2000)
Cytokine
, vol.12
, pp. 972
-
-
Chen, X.P.1
Ding, X.2
Daynes, R.A.3
-
34
-
-
17644441326
-
Altered T cell surface glycosylation in HIV-1 infection results in increased susceptibility to galectin-1-induced cell death
-
Lanteri, M., Giordanengo, V., Hiraoka, N. et al. 2003. Altered T cell surface glycosylation in HIV-1 infection results in increased susceptibility to galectin-1-induced cell death. Glycobiology 13:909.
-
(2003)
Glycobiology
, vol.13
, pp. 909
-
-
Lanteri, M.1
Giordanengo, V.2
Hiraoka, N.3
-
35
-
-
0026584108
-
Cleavage of the cell-surface O-sialoglycoproteins CD34, CD43, CD44, and CD45 by a novel glycoprotease from Pasteurella haemolytica
-
Sutherland, D. R., Abdullah, K. M., Cyopick, P. and Mellors, A. 1992. Cleavage of the cell-surface O-sialoglycoproteins CD34, CD43, CD44, and CD45 by a novel glycoprotease from Pasteurella haemolytica. J. Immunol. 148:1458.
-
(1992)
J. Immunol.
, vol.148
, pp. 1458
-
-
Sutherland, D.R.1
Abdullah, K.M.2
Cyopick, P.3
Mellors, A.4
-
36
-
-
0035164222
-
Absence of CD43 fails to alter T cell development and responsiveness
-
Carlow, D. A., Corbel, S. Y. and Ziltener, H. J. 2001. Absence of CD43 fails to alter T cell development and responsiveness. J. Immunol. 166:256.
-
(2001)
J. Immunol.
, vol.166
, pp. 256
-
-
Carlow, D.A.1
Corbel, S.Y.2
Ziltener, H.J.3
-
37
-
-
2442472174
-
CD43 regulation of T cell activation is not through steric inhibition of T cell-APC interactions but through an intracellular mechanism
-
Tong, J., Allenspach, E. J., Takahashi, S. M. et al. 2004. CD43 regulation of T cell activation is not through steric inhibition of T cell-APC interactions but through an intracellular mechanism. J. Exp. Med. 199:1277.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1277
-
-
Tong, J.1
Allenspach, E.J.2
Takahashi, S.M.3
-
38
-
-
0029065528
-
CD43 is a murine Tcell costimulatory receptor that functions independently of CD28
-
Sperling, A. I., Green, J. M., Mosley, R. L. et al. 1995. CD43 is a murine Tcell costimulatory receptor that functions independently of CD28. J. Exp. Med. 182:139.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 139
-
-
Sperling, A.I.1
Green, J.M.2
Mosley, R.L.3
-
39
-
-
0037304929
-
Role of protein tyrosine phosphatases in T cell activation
-
Mustelin, T., Rahmouni, S., Bottini, N. and Alonso, A. 2003. Role of protein tyrosine phosphatases in T cell activation. Immunol. Rev. 191:139.
-
(2003)
Immunol. Rev.
, vol.191
, pp. 139
-
-
Mustelin, T.1
Rahmouni, S.2
Bottini, N.3
Alonso, A.4
-
40
-
-
0000072679
-
Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase
-
Mustelin, T., Coggeshall, K. M. and Altman, A. 1989. Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase. Proc. Natl Acad. Sci. USA 86:6302.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 6302
-
-
Mustelin, T.1
Coggeshall, K.M.2
Altman, A.3
-
41
-
-
0026612351
-
Regulation of the p59fyn protein tyrosine kinase by the CD45 phosphotyrosine phosphatase
-
Mustelin, T., Pessa-Morikawa, T., Autero, M. et al. 1992. Regulation of the p59fyn protein tyrosine kinase by the CD45 phosphotyrosine phosphatase. Eur. J. Immunol. 22:1173.
-
(1992)
Eur. J. Immunol.
, vol.22
, pp. 1173
-
-
Mustelin, T.1
Pessa-Morikawa, T.2
Autero, M.3
-
42
-
-
0028346560
-
CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development
-
Trowbridge, I. S. and Thomas, M. L. 1994. CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development. Annu. Rev. Immunol. 12:85.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 85
-
-
Trowbridge, I.S.1
Thomas, M.L.2
-
43
-
-
0030222017
-
Protein tyrosine phosphatases in T-cell development, apoptosis and signalling
-
Frearson, J. A. and Alexander, D. R. 1996. Protein tyrosine phosphatases in T-cell development, apoptosis and signalling. Immunol. Today 17:379.
-
(1996)
Immunol. Today
, vol.17
, pp. 379
-
-
Frearson, J.A.1
Alexander, D.R.2
-
44
-
-
0024416009
-
Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation
-
Pingel, J. T. and Thomas, M. L. 1989. Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation. Cell 58:1055.
-
(1989)
Cell
, vol.58
, pp. 1055
-
-
Pingel, J.T.1
Thomas, M.L.2
-
45
-
-
0021020298
-
T cells discriminate between Ia antigens expressed on allogeneic accessory cells and B cells: A potential function for carbohydrate side chains on Ia molecules
-
Cowing, C. and Chapdelaine, J. M. 1983. T cells discriminate between Ia antigens expressed on allogeneic accessory cells and B cells: A potential function for carbohydrate side chains on Ia molecules. Proc. Natl Acad. Sci. USA 80:6000.
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 6000
-
-
Cowing, C.1
Chapdelaine, J.M.2
-
46
-
-
0023202140
-
Cell surface sialic acid influences tumor cell recognition in the mixed lymphocyte reaction
-
Powell, L. D., Whiteheart, S. W. and Hasegawa, A. 1987. Cell surface sialic acid influences tumor cell recognition in the mixed lymphocyte reaction. J. Immunol. 139:262.
-
(1987)
J. Immunol.
, vol.139
, pp. 262
-
-
Powell, L.D.1
Whiteheart, S.W.2
Hasegawa, A.3
-
47
-
-
0033179268
-
A novel CD8 T cell-restricted CD45RB epitope shared by CD43 is differentially affected by glycosylation
-
Carlow, D. A., Ardman, B. and Ziltener, H. J. 1999. A novel CD8 T cell-restricted CD45RB epitope shared by CD43 is differentially affected by glycosylation. J. Immunol. 163:1441.
-
(1999)
J. Immunol.
, vol.163
, pp. 1441
-
-
Carlow, D.A.1
Ardman, B.2
Ziltener, H.J.3
|