A novel CD8 T cell-restricted CD45RB epitope shared by CD43 is differentially affected by glycosylation

Journal of Immunology

Volumn 163, Issue 3, 1999, Pages 1441-1448

  Carlow, Douglas A ^a   Ardman, Blair ^b   Ziltener, Hermann J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b TUFTS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; CD8 ANTIGEN; EPITOPE; GLYCAN; LEUKOSIALIN; MONOCLONAL ANTIBODY; SIALIC ACID; SIALIDASE;

ANIMAL CELL; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; GLYCOSYLATION; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; THYMOCYTE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD43; ANTIGENS, CD45; BINDING SITES, ANTIBODY; CD8-POSITIVE T-LYMPHOCYTES; EPITOPES, T-LYMPHOCYTE; EXONS; GLYCOSYLATION; LYMPH NODES; MICE; MICE, INBRED BALB C; MOLECULAR WEIGHT; N-ACETYLGLUCOSAMINYLTRANSFERASES; N-ACETYLNEURAMINIC ACID; NEURAMINIDASE; PRECIPITIN TESTS; PROTEIN ISOFORMS; SIALOGLYCOPROTEINS; THYMOMA; TUMOR CELLS, CULTURED;

EID: 0033179268     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Cyster, J. G., D. M. Shotton, and A. F. Williams. 1991. The dimensions of the T lymphocyte glycoprotein leukosialin and identification of linear protein epitopes that can be modified by glycosylation. EMBO J. 10:893.
2. Ostberg, J. R., R. K. Barth, and J. G. Frelinger. 1998. The Roman god Janus: a paradigm for the function of CD43. Immunol. Today 19:546.
3. Manjunath, N., M. Correa, M. Ardman, and B. Ardman. 1995. Negative regulation of T-cell adhesion and activation by CD43. Nature 377:535.
4. Stockton, B. M., G. Cheng, N. Manjunath, B. Ardman, and U. H. von Andrian. 1998. Negative regulation of T cell homing by CD43. Immunity 8:373.
5. Woodman, R. C., B. Johnston, M. J. Hickey, D. Teoh, P. Reinhardt, B. Y. Poon, and P. Kubes. 1998. The functional paradox of CD43 in leukocyte recruitment: a study using CD43-deficient mice. J. Exp. Med. 188:2181.
6. Jones, A. T., B. Federsppiel, L. G. Ellies, M. J. Williams, R. Burgener, V. Duronio, C. A. Smith, F. Takei, and H. J. Ziltener. 1994. Characterization of the activation-associated isoform of CD43 on mutine T lymphocytes J. Immunol. 153:3426.
7. Baecher-Allan, C. M., J. D. Kemp, K. S. Dorfman, R. K. Barth, and J. G. Frelinger. 1993. Differential epitope expression of Ly-48 (mouse leukosialin). Immunogenetics 37:183.
8. Giordanengo, V., M. Limouse, J. F. Peyron, and J. C. Lefebvre. 1995. Lymphocytic CD43 and CD45 bear sulfate residues potentially implicated in cell to cell interactions. Eur. J. Immunol. 25:274.
9. Barran, P., W. Fellinger, C. E. Warren, J. W. Dennis, and H. J. Ziltener. 1997. Modification of CD43 and other lymphocyte O-glycoproteins by core 2 N-acetylglucosaminyltransferase. Glycobiology 7:129.
10. Higgins, E. A., K. A. Siminovitch, D. L. Zhuang, I. Brockhausen, and J. W. Dennis. 1991. Aberrant O-linked oligosaccharide biosynthesis in lymphocytes and platelets from patients with the Wiskott-Aldrich syndrome. J. Biol. Chem. 266:6280.
11. + T lymphocytes in graft-versus-host disease. Glycobiology 4:885.
12. Ellies, L. G., W. Tao, W. Fellinger, H. S. Teh, and H. J. Ziltener. 1996. The CD43 130-kD peripheral T-cell activation antigen is downregulated in thymic positive selection. Blood 88:1725.
13. Ellies, L. G., S. Tsuboi, B. Petryniak, J. B. Lowe, M. Fukuda, and J. D. Marth. 1998. Core 2 oligosaccharide biosynthesis distinguishes between selectin ligands essential for leukocyte homing and inflammation. Immunity 9:881.
14. Trowbridge, I. S. 1978. Interspecies spleen-myeloma hybrid producing monoclonal antibodies against mouse lymphocyte surface glycoprotein, T200. J. Exp. Med. 148:313.
15. Birkeland, M. L., P. Johnson, I. S. Trowbridge, and E. Pure. 1989. Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation. Proc. Natl. Acad. Sci. USA 86:6734.
16. Hawley, R. G., A. Z. Fong, B. Y. Ngan, V. M. de Lanux, S. C. Clark, and T. S. Hawley. 1993. Progenitor cell hyperplasia with rare development of myeloid leukemia in interleukin 11 bone marrow chimeras. J. Exp. Med. 178:1175.
17. Schrader, J. W., and R. M. Crapper. 1983. Autogenous production of a hemopoietic growth factor, persisting-cell-stimulating factor, as a mechanism for transformation of bone marrow-derived cells. Proc. Natl. Acad. Sci. USA 80:6892.
18. Gillis, S., and K. A. Smith. 1977. Long term culture of tumour-specific cytotoxic T cells. Nature 268:154 (Lett.).
19. Basadonna, G. P., L. Auersvald, C. Q. Khuong, X. X. Zheng, N. Kashio, D. Zekzer, M. Minozzo, H. Qian, L. Visser, A. Diepstra, et al. 1998. Antibody-mediated targeting of CD45 isoforms: a novel immunotherapeutic strategy. Proc. Natl. Acad. Sci. USA 95:3821.
20. Trowbridge, I. S., P. Johnson, H. Ostergaard, and N. Hole. 1992. Structure and function of CD45: a leukocyte-specific protein tyrosine phosphatase. Adv. Exp. Med. Biol. 323:29.
21. Plas, D. R., and M. L. Thomas. 1998. Negative regulation of antigen receptor signaling in lymphocytes. J. Mol. Med. 76:589.
22. Bork, P., and R. F. Doolittle. 1993. Fibronectin type III modules in the receptor phosphatase CD45 and tapeworm antigens. Protein Sci. 2:1185.
23. Thomas, M. L. 1989. The leukocyte common antigen family. Annu. Rev. Immunol. 7:339.
24. Thomas, M. L., and L. Lefrancois. 1988. Differential expression of the leucocyte-common antigen family. Immunol. Today 9:320.
25. Lefrancois, L., M. L. Thomas, M. J. Bevan, and I. S. Trowbridge. 1986. Different classes of T lymphocytes have different mRNAs for the leukocyte-common antigen, T200. J. Exp. Med. 163:1337.
26. Okumura, M., R. J. Matthews, B. Robb, G. W. Litman, P. Bork, and M. L. Thomas. 1996. Comparison of CD45 extracellular domain sequences from divergent vertebrate species suggests the conservation of three fibronectin type III domains. J. Immunol. 157:1569.
27. Kishihara, K., J. Penninger, V. A. Wallace, T. M. Kundig, K. Kawai, A. Wakeham, E. Timms, K. Pfeffer, P. S. Ohashi, M. L. Thomas, et al. 1993. Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice. Cell 74:143.
28. fyn tyrosine kinases and CD45 protein tyrosine phosphatase in T-cell development and clonal selection. Immunol. Rev. 135:183.
29. Kozieradzki, I., T. Kundig, K. Kishihara, C. J. Ong, D. Chiu, V. A. Wallace, K. Kawai, E. Timms, J. Ionescu, P. Ohashi, et al. 1997. T cell development in mice expressing splice variants of the protein tyrosine phosphatase CD45. J. Immunol. 158:3130.
30. Lefebvre, J. C., V. Giordanengo, M. Limouse, A. Doglio, M. Cucchiarini, F. Monpoux, R. Mariani, and J. F. Peyron. 1994. Altered glycosylation of leukosialin, CD43, in HIV-1-infected cells of the CEM line. J. Exp. Med. 180:1609.
31. Landolfi, N. F., J. Leone, J. E. Womack, and R. G. Cook. 1985. Activation of T lymphocytes results in an increase in H-2-encoded neuraminidase. Immunogenetics 22:159.
32. + T cells from naive cells. J. Immunol. 161:641.
33. Shimizu, Y., and S. Shaw. 1993. Cell adhesion: mucins in the mainstream. Nature 366:630.
34. Cyster, J. G., D. Fowell, and A. N. Barclay. 1994. Antigenic determinants encoded by alternatively spliced exons of CD45 are determined by the polypeptide but influenced by glycosylation. Int. Immunol. 6:1875.
35. Woollett, G. R., A. F. Williams, and D. M. Shotton. 1985. Visualisation by low-angle shadowing of the leucocyte-common antigen: a major cell surface glycoprotein of lymphocytes. EMBO J. 4:2827.
36. Maemura, K., and M. Fukuda. 1992. Poly-N-acetyllactosaminyl O-glycans attached to leukosialin: the presence of sialyl Le(x) structures in O-glycans. J. Biol. Chem. 267:24379.
37. Kuhns, W., V. Rutz, H. Paulsen, K. L. Matta, M. A. Baker, M. Barner, M. Granovsky, and I. Brockhausen. 1993. Processing O-glycan core I, Galβ1-3GalNAcα-R: specificities of core 2, UDP-GlcNAc: Galβ1-3 GalNAc-R(Glc-NAc to GalNAc)β6-N-acetylglucosaminyltransferase and CMP-sialic acid: Galβ1-3GalNAc-Rα3-sialyltransferase. Glycoconj. J. 10:381.
38. Ropp, P. A., M. R. Little, and P. W. Cheng. 1991. Mucin biosynthesis: purification and characterization of a mucin β6N-acetylglucosaminyltransferase. J. Biol. Chem. 266:23863.
39. Robson, S. C., J. B. Siegel, and R. E. Kirsch. 1996. Inhibition of T cell mitogenesis by a novel anti-CD45R monoclonal antibody. Immunol. Cell Biol. 74:65.
40. Fukuda, M. 1994. Cell Surface Carbohydrates: Cell-Type Specific Expression. Oxford University Press, Oxford.