Topiramate monotherapy as broad-spectrum antiepileptic drug in a naturalistic clinical setting

Seizure

Volumn 14, Issue 6, 2005, Pages 371-380

  Guerrini, Renzo ^a   Carpay, Johannes ^b   Grošelj, Jože ^c   van Oene, Joop ^d   Schreiner, Andreas ^d   Lahaye, Marjolein ^d   Schwalen, Susanne ^d   Lagae, L ^d   Sadzot, B ^d   Van Bogaert, P ^d   van Rijckevorsel, K ^d   Willems, C ^d   Alexiev, A ^d   Bojinov, S ^d   Chavdarov, D ^d   Ganeva, G ^d   Minchev, D ^d   Hajnsek Propadalo, S ^d   Lusic, I ^d   Marusic Della Marina, B ^d   Paucic Kirincic, E ^d   Poljakovic, Z ^d   Skarpa, D ^d   Valic, I ^d   Andersen, A ^d   Anthonisen, B ^d   Gronbech Jensen M ^d   Gulliksen, G ^d   Jansen, J ^d   Luhdorf, K ^d   Mai, J ^d   Ostergaard S ^d   Sorensen T ^d   Thorvaldsen, P ^d   Worm, M ^d   Talvik, I ^d   Barthez, M ^d   De Toffol, B ^d   Derambure, P ^d   Hirsch, E ^d   Josien, E ^d   Pedespan, J ^d   Rouselle, C ^d   McKee, P ^d   Smith, P ^d   Balogiannis, S ^d   Diamantopoulos, N ^d   Karageorgioy, K ^d   Kyritsis, A ^d   Mylonas, I ^d   Papavasiliou, A ^d   Piperidoy, H ^d   Vassilopoulos, D ^d   Neufeld, M ^d   Rabey, M ^d   Aguglia, U ^d   Balestri, P ^d   Capovilla, G ^d   Cristofori, G ^d   Di Perri, R ^d   Ganga, A ^d   Garofalo, P G ^d   Gigli, G L ^d   Gobbi, G ^d   Manfredi, M ^d   Marciani, M G ^d   Martinuzzi, A ^d   Michelucci, R ^d   Minicucci, F ^d   Romeo, A ^d   Sasanelli, F ^d   Veggiotti, P ^d   Zucca, C ^d   Al Yamani, S ^d   Jan, M ^d   Yaqub, B ^d   Al Shubaili, A ^d   Vtols, E ^d   Mikati, M ^d   Bejjani, P ^d   Riachi, N ^d   Den Hartog, G W A ^d   Hagemans, J J M ^d   Hillegers, J P M ^d   Kamphuis, D J ^d   Keunen, R W M ^d   Koehler, P J J ^d   Leyten, Q A H ^d   Pop, P H M ^d   Smits, M G ^d   Van der Leeuw, H J M ^d   Van Donselaar, C A ^d   Veering, M M ^d   Albretsen, C ^d   Hagen, T ^d   Kass B ^d   Kinge, E ^d   Lillebo A ^d   Svendsen, T ^d   more..

^a UNIVERSITY OF PISA   (Italy)

^b Gooi Noord Hospital   (Netherlands)

^c Psychiatric Clinical Hospital Ljubljana   (Slovenia)

^d Janssen Cilag EMEA ^*

Author keywords

Antiepileptic drug; Broad spectrum; Focal epilepsy; Generalized epilepsy; Monotherapy; Topiramate

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; LAMOTRIGINE; OXCARBAZEPINE; PHENYTOIN; TOPIRAMATE; VALPROIC ACID;

ADOLESCENT; ADULT; AGED; ANOREXIA; ARTICLE; CHILD; CLINICAL TRIAL; DIZZINESS; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; FOCAL EPILEPSY; FOLLOW UP; GENERALIZED EPILEPSY; HEADACHE; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; MULTICENTER STUDY; NAUSEA; NEPHROLITHIASIS; OBESITY; PARESTHESIA; PRIORITY JOURNAL; SIDE EFFECT; SOMNOLENCE; TREATMENT OUTCOME; WEIGHT REDUCTION;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANTICONVULSANTS; BODY WEIGHT; CHILD; CHILD, PRESCHOOL; EPILEPSY; FEMALE; FRUCTOSE; HUMANS; INFANT; MALE; MIDDLE AGED; PATIENT SATISFACTION;

EID: 23844472863     PISSN: 10591311     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.seizure.2005.05.001     Document Type: Article

References (27)

1. M.A. King M.R. Newton G.D. Jackson G.J. Fitt L.A. Mitchell M.J. Silvapulle et al. Epileptology of the first-seizure presentation: A clinical, electroencephalographic, and magnetic resonance imaging study of 300 consecutive patients Lancet 352 1998 1007-1011
2. A. Gil-Nagel Review of new antiepileptic drugs as initial therapy Epilepsia 44 Suppl. 4 2003 3-10
3. J.A. French A.M. Kanner J. Bautista B. Abou-Khalil T. Browne C.L. Harden et al. Efficacy and tolerability of the new antiepileptic drugs I: Treatment of new onset epilepsy. Report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society Neurology 62 2004 1252-1260
4. J.A. French A.M. Kanner J. Bautista B. Abou-Khalil T. Browne C.L. Harden et al. Efficacy and tolerability of the new antiepileptic drugs II: Treatment of refractory epilepsy. Report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society Neurology 62 2004 1261-1273
5. D.A. Coulter S. Sombati R.J. DeLorenzo Selective effects of topiramate on sustained repetitive firing and spontaneous bursting in cultured hippocampal neurons Epilepsia 34 Suppl. 2 1993 123
6. S.D. Brown H.H. Wolf E.A. Swinyard R.E. Twyman H.S. White The novel anticonvulsant topiramate enhances GABA-mediated chloride flux Epilepsia 34 Suppl. 2 1993 122-123
7. H.S. White S.D. Brown J.H. Woodhead G.A. Skeen H.H. Wolf Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold Epilepsy Res 28 1997 167-179
8. R.P. Shank J.F. Gardocki J.L. Vaugth C.B. Davis J.J. Schupsky R.B. Raffa et al. Topiramate: Preclinical evaluation of a structurally novel anticonvulsant Epilepsia 35 1994 450-460
9. X. Zhang A.A. Velumian O.T. Jones P.L. Carlen Modulation of high-voltage-activated calcium channels in dentate granule cells by topiramate Epilepsia 41 Suppl. 1 2000 52-60
10. B.E. Maryanoff S.O. Nortey J.F. Gardocki R.P. Shank S.P. Dodgson Anticonvulsant O-alkyl sufamates. 2,3:4,5-bis-O-(1-methylethylidene)-β- d -fructopyranose sulfamate and related compounds J Med Chem 30 1987 880-887
11. R.C. Sachdeo R.A. Reife P. Lim G. Pledger Topiramate monotherapy for partial onset seizures Epilepsia 38 1997 294-300
12. F.G. Gilliam et al. A dose-comparison trial of topiramate as monotherapy in recently diagnosed partial epilepsy Neurology 60 2003 196-202
13. EPMN 105 Study Group. Topiramate, carbamazepine and valproate monotherapy: Double-blind comparison in newly diagnosed epilepsy. Acta Neurol Scand 2003;107:165-175.
14. S. Arroyo L. Squires S. Wang R. Twyman Topiramate: Effective as monotherapy in dose-response study in newly diagnosed epilepsy Epilepsia 43 Suppl. 7 2002 241
15. Commission of Classification and Terminology of the International League Against Epilepsy. Proposal for revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia 1981;22:489-501.
16. Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for classification of epilepsies and epileptic syndromes. Epilepsia 1989; 30:389-399.
17. M. Reunanen M. Dam A.W.C. Yuen A randomised open multicentre comparative trial of lamotrigine and carbamazepine as monotherapy in patients with newly diagnosed or recurrent epilepsy Epilepsy Res 23 1996 149-155
18. T.J. Steiner C.I. Dellaportas L.J. Findley M. Gross F.B. Gibberd G.D. Perkin et al. Lamotrigine monotherapy in newly diagnosed epilepsy. A double-blind comparison with phenytoin Epilepsia 40 1999 601-607
19. L. Kaminow J.R. Schimschock A.E. Hammer A. Vuong Lamotrigine monotherapy compared with carbamazepine, phenytoin, or valproate monotherapy in patients with epilepsy Epilepsy Behav 4 2003 659-666
20. D.W. Chadwick H. Anhut M.J. Greiner J. Alexander G.H. Murray E.A. Garofalo et al. A double-blind trial of gabapentin monotherapy for newly diagnosed partial seizures. International Gabapentin Monotherapy Study Group 945-77 Neurology 51 2001 1282-1288
21. Lamictal vs. Carbamazepine Group. Epilepsy Res 2001;46:145-155.
22. P. Kwan M.J. Brodie Early identification of refractory epilepsy N Engl J Med 342 2000 314-319
23. Gabapentin Study Group. Gabapentin versus lamotrigine monotherapy: A double-blind comparison in newly diagnosed epilepsy. Epilepsia 2002;43:993-1000.
24. R. Salinas-Estabane Topiramate monotherapy in adults with newly diagnosed epilepsy Adv Ther 19 2002 126-128
25. A.G. Wasserstein I. Rak R.A. Reife Investigation of the mechanistic basis for topiramate-associated nephrolithiasis, examination of urinary and serum constituents Epilepsia 36 Suppl. 3 1995 153
26. US Topiramate Study Group. A 6-month randomised, placebo-controlled, dose-ranging trial of topiramate for weight loss in obesity. Obes Res 2003;11:722-733.
27. E. Ben-Menachem M. Axelsen E.H. Johanson A. Stage U. Smith Predictors of weight loss in adults with topiramate-treated epilepsy Obes Res 11 2003 556-562