Association of low red blood cell folate concentrations with coronary artery disease in Iranians: A matched case-control study

Journal of Vascular Research

Volumn 42, Issue 4, 2005, Pages 325-330

  Golbahar, Jamal ^a   Rezaian, Golamreza ^a   Fathi, Z ^a   Aminzadeh, Mohammad A ^a  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

5 Methyltetrahydrofolate; Coronary artery disease; Homocysteine; Red blood cells; Remethylation pathway

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; CYANOCOBALAMIN; HOMOCYSTEINE;

ADULT; ANGIOGRAPHY; ARTICLE; COMPARATIVE STUDY; CONFIDENCE INTERVAL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; ERYTHROCYTE; FEMALE; FOLIC ACID BLOOD LEVEL; GEOMETRY; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; METHYLATION; PLASMA; PREVALENCE; PRIORITY JOURNAL; RISK ASSESSMENT;

ADULT; AGED; CASE-CONTROL STUDIES; CORONARY DISEASE; ERYTHROCYTES; FEMALE; FOLIC ACID; HOMOCYSTEINE; HUMANS; IRAN; MALE; MIDDLE AGED; TETRAHYDROFOLATES;

EID: 23844441005     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000086460     Document Type: Article

References (27)

1. Moat SJ, Lang D, McDowell IF, et al: Folate, homocysteine, endothelial function and cardiovascular disease. J Nutr Biochem 2004;15:64-79.
2. Hankey GJ, Eikelboom JW, Ho WK, van Bockxmeer FM: Clinical usefulness of plasma homocysteine in vascular disease. Med J Aust 2004;181:314-318.
3. Kalra DK: Homocysteine and cardiovascular disease. Curr Atheroscler Rep 2004;6:101-106.
4. Graham IM, Daly LE, Refsum HM, et al: Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project. JAMA 1997;277:1775-1781.
5. Wald DS, Law M, Morris JK: Homocysteine and cardiovascular disease: Evidence on causality from a meta-analysis. BMJ 2002;325:1202-1206.
6. Liem A, Reynierse-Buitenwerf GH, Zwinderman AH, Jukema JW, van Veldhuisen DJ: Secondary prevention with folic acid: effects on clinical outcomes. J Am Coll Cardiol 2003;41:2105-2113.
7. Toole JF, Malinow MR, Chambless LE, et al: Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. JAMA 2004;291:565-575.
8. Alfthan G, Aro A, Gey KF: Plasma homocysteine and cardiovascular disease mortality. Lancet 1997;349:397.
9. Chambers JC, Obeid OA, Refsum H, et al: Plasma homocysteine concentrations and risk of coronary heart disease in UK Indian Asian and European men. Lancet 2000;355:523-527.
10. Molloy AM, Daly S, Mills JL: Thermolabile variant of 5,10- methylenetetrahydrofolate reductase associated with low red-cell folates: implications for folate intake recommendations. Lancet 1997;349:1591-1593.
11. Gilfix BM, Blank DW, Rosenblatt DS: Novel reductant for determination of total plasma homocysteine. Clin Chem 1997;43:687-688.
12. Girelli D, Martinelli N, Pizzolo F, et al: The interaction between MTHFR 677 C→T genotype and folate status is a determinant of coronary atherosclerosis risk. J Nutr 2003;33:1281-1285.
13. Silberberg JS, Crooks RL, Wlodarczyk JH, Fryer JL: Association between plasma folate and coronary disease independent of homocysteine. Am J Cardiol 2001;87:1003-1004.
14. Hung J, Beilby JP, Knuiman MW, Divitini MI: Folate and vitamin B-12 and risk of fatal cardiovascular disease: cohort study from Busselton, Western Australia. BMJ 2003;326:131.
15. Folsom AR, Nieto FJ, McGovern PG, et al: Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins: the Atherosclerosis Risk in Communities (ARIC) study. Circulation 1998;98: 204-210.
16. Giles WH, Kittner SJ, Croft JB, Anda RF, Casper ML, Ford ES: Serum folate and risk for coronary heart disease: results from a cohort of US adults. Ann Epidemiol1998;8:490-496.
17. Michalis LK, Pappas K, Tweddel A, et al: Relatively low red cell folate levels and acute coronary syndromes. Coron Artery Dis 2001;12:665-668.
18. Robinson K, Arheart K, Refsum H, et al: Low circulating folate and vitamin B6 concentrations: risk factors for stroke, peripheral vascular disease, and coronary artery disease. European COMAC Group. Circulation 1998;97:437-443.
19. Herbert V: Development of human folate deficiency; in Picano MF, Stockstad ELR, Gregory JF (eds): Folic Acid Metabolism in Health and Disease. New York, Wiley-Liss, 1990, pp 195-210.
20. Antony AC: Megaloblastic anemia; in Hoffman R, Benz EJ, Shattil S, Furie B, Cohen HJ (eds): Hematology: Basic Principles and Practice. Philadelphia, Churchill Livingstone, 1991, pp 394-423.
21. Choumenkovitch SF, Jacques PF, Nadeau MR, Wilson PW, Rosenberg IH, Selhub J: Folic acid fortification increases red blood cell folate concentrations in the Framingham study. J Nutr 2001;131:3277-3280.
22. Selhub J, Jacques PF, Bostom AG, et al: Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis. N Engl J Med 1995;332:286-291.
23. Quere I, Perneger TV, Zittoun J, et al: Red blood cell methylfolate and plasma homocysteine as risk factors for venous thromboembolism: a matched case-control study. Lancet 2002;359:747-752.
24. Joshi R, Adhikari S, Patro BS, Chattopadhyay S, Mukherjee T: Free radical scavenging behavior of folk acid: evidence for possible antioxidant activity. Free Radic Biol Med 2001;30:1390-1399.
25. Doshi SN, McDowell IF, Moat SJ, et al: Folate improves endothelial function in coronary artery disease: an effect mediated by reduction of intracellular superoxide? Arterioscler Thromb Vasc Biol 2001;21:1196-1202.
26. Doshi SN, McDowell IF, Moat SJ, et al: Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering. Circulation 2002;105:22-26.
27. Hyndman ME, Verma S, Rosenfeld RJ, Anderson TJ, Parsons HG: Interaction of 5-methyl-tetrahydrofolate and tetrahydrobiopterin on endothelial function. Am J Physiol Heart Circ Physiol 2002;282:H2167-H2172.