New frontiers in immunology. Workshop on The Road Ahead: Future Directions in Fundamental and Clinical Immunology

EMBO Reports

Volumn 6, Issue 7, 2005, Pages 620-623

  Beutler, Bruce ^a   Casanova, Jean Laurent ^b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b IMAGINE INSTITUTE   (France)

Author keywords

Auto immunity; Immunity; Infection; Tolerance

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD16 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; GUANINE NUCLEOTIDE BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 12; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; T LYMPHOCYTE RECEPTOR; TOLL LIKE RECEPTOR;

ARABIDOPSIS; AUTOIMMUNITY; BACTERIAL IMMUNITY; CAENORHABDITIS ELEGANS; CLINICAL IMMUNOLOGY; CONFERENCE PAPER; CYTOKINE PRODUCTION; CYTOLOGY; CYTOTOXIC T LYMPHOCYTE; DISEASE COURSE; DROSOPHILA MELANOGASTER; GENE MUTATION; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOGENETICS; IMMUNOLOGICAL TOLERANCE; INNATE IMMUNITY; MAMMAL; MICROBIAL IMMUNITY; MOUSE; NATURAL KILLER CELL; NONHUMAN; PARASITE IMMUNITY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SERRATIA MARCESCENS; SIGNAL TRANSDUCTION; T LYMPHOCYTE; VIRUS IMMUNITY; WORKSHOP;

ANIMALS; IMMUNITY, NATURAL; INFECTION; KILLER CELLS, NATURAL; T-LYMPHOCYTES;

ARABIDOPSIS; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; MAMMALIA; NEGIBACTERIA; POSIBACTERIA; SERRATIA MARCESCENS;

EID: 23744500805     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.embor.7400457     Document Type: Conference Paper

References (22)

1. Ardouin L, Rolink AG, Mura AM, Gommeaux J, Melchers F, Busslinger M, Malissen M, Malissen B (2005) Rapid in vivo analysis of mutant forms of the LAT adaptor using Pax5-Lat double-deficient pro-B cells. Eur J Immunol 35: 977-986
2. Beutler B, Rietschel ET (2003) Innate immune sensing and its roots: the story of endotoxin. Nat Rev Immunol 3: 169-176
3. Beutler B, Crozat K, Koziol JA, Georgel P (2005) Genetic dissection of innate immunity to infection: the mouse cytomegalovirus model. Curr Opin Immunol 17: 36-43
4. Casanova JL, Abel L (2004) The human model: a genetic dissection of immunity to infection in natural conditions. Nat Rev Immunol 4: 55-66
5. Casanova JL, Schurr E, Abel L, Skamene E (2002) Forward genetics of infectious diseases: immunological impact. Trends Immunol 23: 469-472
6. Girardin SE, Philpott DJ (2004). Mini-review: the role of peptidoglycan recognition in innate immunity. Eur J Immunol 34: 1777-1782
7. Gouin E, Welch MD, Cossart P (2005) Actin-based motility of intracellular pathogens. Curr Opin Microbiol 8: 35-45
8. Hugues S, Fetler L, Bonifaz L, Helft J, Amblard F, Amigorena S (2004) Distinct T cell dynamics in lymph nodes during the induction of tolerance and immunity. Nat Immunol 5: 1235-1242
9. Karre K (2002) NK cells, MHC class I molecules and the missing self. Scand J Immunol 55: 221-228
10. Kornfeld C et al (2005) Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS. J Clin Invest 115: 1082-1091
11. Lapaque N, Moriyon I, Moreno E, Gorvel JP (2005) Brucella lipopolysaccharide acts as a virulence factor. Curr Opin Microbiol 8: 60-66
12. Martens S, Sabel K, Lange R, Uthaiah R, Wolf E, Howard JC (2004) Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis. J Immunol 173: 2594-2606
13. Matzinger P (2002) The danger model: a renewed sense of self. Science 296: 301-305
14. Moretta L, Bottino C, Pende D, Vitale M, Mingari MC, Moretta A (2004) Different checkpoints in human NK-cell activation. Trends Immunol 25: 670-676
15. + Tregs: limiting collateral damage. J Clin Invest 114: 1372-1378
16. Patel JC, Galan JE (2005) Manipulation of the host actin cytoskeleton by Salmonella - all in the name of entry. Curr Opin Microbiol 8: 10-15
17. Schulenburg H, Kurz CL, Ewbank JJ (2004) Evolution of the innate immune system: the worm perspective. Immunol Rev 198: 36-58
18. Stinchcombe J, Bossi G, Griffiths GM (2004) Linking albinism and immunity: the secrets of secretory lysosomes. Science 305: 55-59
19. Takaoka A et al (2005) Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature 434: 243-249
20. Vivier E, Nunes JA, Vely F (2004) Natural killer cell signaling pathways. Science 306: 1517-1519
21. Vodovar N, Acosta C, Lemaitre B, Boccard F (2004) Drosophila: a polyvalent model to decipher host-pathogen interactions. Trends Microbiol 12: 235-242
22. Zucchelli S, Holler P, Yamagata T, Roy M, Benoist C, Mathis D (2005) Defective central tolerance induction in NOD mice: genomics and genetics. Immunity 22: 385-396