메뉴 건너뛰기




Volumn 1041, Issue , 2005, Pages 256-271

The pregnancy hormone relaxin binds to and activates the human glucocorticoid receptor

Author keywords

Cytokines; Glucocorticoids; Macrophages; Receptor; Signal transduction

Indexed keywords

CYTOKINE; DNA; ENDOTOXIN; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; INTERLEUKIN 1; INTERLEUKIN 6; LUCIFERASE; RELAXIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 23644461401     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1282.039     Document Type: Conference Paper
Times cited : (13)

References (28)
  • 2
    • 0038364161 scopus 로고    scopus 로고
    • Relaxin: A pregnancy hormone as central player of body fluid and circulation homeostasis
    • DSCHIETZIG, T. & K. STANGL. 2003. Relaxin: a pregnancy hormone as central player of body fluid and circulation homeostasis. Cell. Mol. Life Sci. 60: 688-700.
    • (2003) Cell. Mol. Life Sci. , vol.60 , pp. 688-700
    • Dschietzig, T.1    Stangl, K.2
  • 3
    • 0031021409 scopus 로고    scopus 로고
    • Relaxin: A pleiotropic hormone
    • BANI, D. 1997. Relaxin: a pleiotropic hormone. Gen. Pharmacol. 28: 13-22.
    • (1997) Gen. Pharmacol. , vol.28 , pp. 13-22
    • Bani, D.1
  • 4
    • 0034810896 scopus 로고    scopus 로고
    • The pregnancy hormone relaxin is a player in human heart failure
    • DSCHIETZIG, T., C. RICHTER, C. BARTSCH, et al. 2001. The pregnancy hormone relaxin is a player in human heart failure. FASEB J. 15: 2187-2195.
    • (2001) FASEB J. , vol.15 , pp. 2187-2195
    • Dschietzig, T.1    Richter, C.2    Bartsch, C.3
  • 5
    • 0037169071 scopus 로고    scopus 로고
    • Activation of orphan receptors by the hormone relaxin
    • HSU, S.Y., K. NAKABAYASHI, S. NISHI, et al. 2002. Activation of orphan receptors by the hormone relaxin. Science 295: 671-674.
    • (2002) Science , vol.295 , pp. 671-674
    • Hsu, S.Y.1    Nakabayashi, K.2    Nishi, S.3
  • 6
    • 0037200034 scopus 로고    scopus 로고
    • INSL3/litereydig insulin-like peptide activates the LGR8 receptor important in testis descent
    • KUMAGAI, J., S. Y. HSU, H. MATSUMI, et al. 2002. INSL3/litereydig insulin-like peptide activates the LGR8 receptor important in testis descent. J. Biol. Chem. 277: 31283-31286.
    • (2002) J. Biol. Chem. , vol.277 , pp. 31283-31286
    • Kumagai, J.1    Hsu, S.Y.2    Matsumi, H.3
  • 8
    • 0030993390 scopus 로고    scopus 로고
    • Relaxin counteracts asthma-like reaction induced by inhaled antigen in sensitized guinea pigs
    • BANI, D., L. BALLATI, E. MASINI, et al. 1997. Relaxin counteracts asthma-like reaction induced by inhaled antigen in sensitized guinea pigs. Endocrinology 138: 1909-1915.
    • (1997) Endocrinology , vol.138 , pp. 1909-1915
    • Bani, D.1    Ballati, L.2    Masini, E.3
  • 9
    • 0033000845 scopus 로고    scopus 로고
    • Relaxin favors the development of activated human T cells into Th1-like effectors
    • PICCINNI, M.P., D. BANI, L. BELONI, et al. 1999. Relaxin favors the development of activated human T cells into Th1-like effectors. Eur. J. Immunol. 29: 2241-2247.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 2241-2247
    • Piccinni, M.P.1    Bani, D.2    Beloni, L.3
  • 10
    • 0030026713 scopus 로고    scopus 로고
    • Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids
    • BAMBERGER, C.M., H.M. SCHULTE & G.P. CHROUSOS. 1996. Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids. Endocr. Rev. 17: 245-261.
    • (1996) Endocr. Rev. , vol.17 , pp. 245-261
    • Bamberger, C.M.1    Schulte, H.M.2    Chrousos, G.P.3
  • 11
    • 0031862891 scopus 로고    scopus 로고
    • Anti-inflammatory actions of glucocorticoids: Molecular mechanisms
    • BARNES, P.J. 1998. Anti-inflammatory actions of glucocorticoids: molecular mechanisms. Clin. Sci. 94: 557-572.
    • (1998) Clin. Sci. , vol.94 , pp. 557-572
    • Barnes, P.J.1
  • 12
    • 0034698087 scopus 로고    scopus 로고
    • The molecular chaperones Hsp90 and Hsc70 are both necessary and sufficient to activate hormone binding by glucocorticoid receptor
    • RAJAPANDI, T., L.E. GREENE & E. EISENBERG. 2000. The molecular chaperones Hsp90 and Hsc70 are both necessary and sufficient to activate hormone binding by glucocorticoid receptor. J. Biol. Chem. 275: 22597-22604.
    • (2000) J. Biol. Chem. , vol.275 , pp. 22597-22604
    • Rajapandi, T.1    Greene, L.E.2    Eisenberg, E.3
  • 13
    • 0036783767 scopus 로고    scopus 로고
    • Expression of glucocorticoid receptor alpha- and beta-isoforms in human cells and tissues
    • PUJOLS, L., J. MULLOL, J. ROCA-FERRER, et al. 2002. Expression of glucocorticoid receptor alpha- and beta-isoforms in human cells and tissues. Am. J. Physiol. Cell Physiol. 283: C1324-C1331.
    • (2002) Am. J. Physiol. Cell Physiol. , vol.283
    • Pujols, L.1    Mullol, J.2    Roca-Ferrer, J.3
  • 14
    • 0033600936 scopus 로고    scopus 로고
    • The dominant negative activity of the human glucocorticoid receptor beta isoform. Specificity and mechanisms of action
    • OAKLEY, R.H., C.M. JEWELL, M.R. YUDT, et al. 1999. The dominant negative activity of the human glucocorticoid receptor beta isoform. Specificity and mechanisms of action. J. Biol. Chem. 274: 27857-27866.
    • (1999) J. Biol. Chem. , vol.274 , pp. 27857-27866
    • Oakley, R.H.1    Jewell, C.M.2    Yudt, M.R.3
  • 15
    • 0027967441 scopus 로고
    • A labile transcriptional repressor modulates endotoxin tolerance
    • LARUE, K.E. & C.E. MCCALL. 1994. A labile transcriptional repressor modulates endotoxin tolerance. J. Exp. Med. 180: 2269-2275.
    • (1994) J. Exp. Med. , vol.180 , pp. 2269-2275
    • Larue, K.E.1    McCall, C.E.2
  • 16
    • 0024462956 scopus 로고
    • Antinuclear antibody in juvenile rheumatoid arthritis sera reacts with 50-40 kDa antigen(s) found in HeLa nuclear extracts
    • HABER, P.L., T.G. OSBORN & T.L. MOORE. 1989. Antinuclear antibody in juvenile rheumatoid arthritis sera reacts with 50-40 kDa antigen(s) found in HeLa nuclear extracts. J. Rheumatol. 16: 949-954.
    • (1989) J. Rheumatol. , vol.16 , pp. 949-954
    • Haber, P.L.1    Osborn, T.G.2    Moore, T.L.3
  • 18
    • 0002294347 scopus 로고
    • A simple sequentially rejective multiple test procedure
    • HOLM, S. 1979. A simple sequentially rejective multiple test procedure. Scand. J. Stat. 6: 65-70.
    • (1979) Scand. J. Stat. , vol.6 , pp. 65-70
    • Holm, S.1
  • 19
    • 0021414791 scopus 로고
    • DNA binding properties of glucocorticosteroid receptors bound to the steroid antagonist RU-486
    • BOURGEOIS, S., M. PFAHL & E.E. BAULIEU. 1984. DNA binding properties of glucocorticosteroid receptors bound to the steroid antagonist RU-486. EMBO J. 3: 751-755.
    • (1984) EMBO J. , vol.3 , pp. 751-755
    • Bourgeois, S.1    Pfahl, M.2    Baulieu, E.E.3
  • 20
    • 0037428061 scopus 로고    scopus 로고
    • Relaxin, a pregnancy hormone, is a functional endothelin-1 antagonist: Attenuation of endothelin-1-mediated vasoconstriction by stimulation of endothelin type-B receptor expression via ERK-1/2 and nuclear factor-kappaB
    • DSCHIETZIG, T., C. BARTSCH, C. RICHTER, et al. 2003. Relaxin, a pregnancy hormone, is a functional endothelin-1 antagonist: attenuation of endothelin-1-mediated vasoconstriction by stimulation of endothelin type-B receptor expression via ERK-1/2 and nuclear factor-kappaB. Circ. Res. 92: 32-40.
    • (2003) Circ. Res. , vol.92 , pp. 32-40
    • Dschietzig, T.1    Bartsch, C.2    Richter, C.3
  • 21
    • 0036143130 scopus 로고    scopus 로고
    • Molecular mechanisms of glucocorticoid antiproliferative effects: Antagonism of transcription factor activity by glucocorticoid receptor
    • ALMAWI, W.Y & O.K. MELEMEDJIAN. 2002. Molecular mechanisms of glucocorticoid antiproliferative effects: antagonism of transcription factor activity by glucocorticoid receptor. J. Leuk. Biol. 71: 9-15.
    • (2002) J. Leuk. Biol. , vol.71 , pp. 9-15
    • Almawi, W.Y.1    Melemedjian, O.K.2
  • 22
    • 0034634628 scopus 로고    scopus 로고
    • The relaxin receptor-binding site geometry suggests a novel gripping mode of interaction
    • BUELLESBACH, E.E. & C. SCHWABE. 2001. The relaxin receptor-binding site geometry suggests a novel gripping mode of interaction. J. Biol. Chem. 275: 35276-35280.
    • (2001) J. Biol. Chem. , vol.275 , pp. 35276-35280
    • Buellesbach, E.E.1    Schwabe, C.2
  • 23
    • 18444405534 scopus 로고    scopus 로고
    • Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition
    • BLEDSOE, R.K., V.G. MONTANA, T.B. STANLEY, et al. 2002. Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition. Cell 110: 93-105.
    • (2002) Cell , vol.110 , pp. 93-105
    • Bledsoe, R.K.1    Montana, V.G.2    Stanley, T.B.3
  • 24
    • 0036792631 scopus 로고    scopus 로고
    • Protective effect of relaxin in cardiac anaphylaxis: Involvement of the nitric oxide pathway
    • MASINI, E., G. ZAGLI, J.F. NDISANG, et al. 2002. Protective effect of relaxin in cardiac anaphylaxis: involvement of the nitric oxide pathway. Br. J. Pharmacol. 137: 337-344.
    • (2002) Br. J. Pharmacol. , vol.137 , pp. 337-344
    • Masini, E.1    Zagli, G.2    Ndisang, J.F.3
  • 25
    • 0023150757 scopus 로고
    • Relaxin affects the release of oxytocin and vasopressin from the neurohypophysis
    • DAYANITHI, G., M. CAZALIS & J.J. NORDMANN. 1987. Relaxin affects the release of oxytocin and vasopressin from the neurohypophysis. Nature 325: 813-816.
    • (1987) Nature , vol.325 , pp. 813-816
    • Dayanithi, G.1    Cazalis, M.2    Nordmann, J.J.3
  • 26
    • 0036454227 scopus 로고    scopus 로고
    • Involvement of the brain oxytocin system in stress coping: Interactions with the hypothalamo-pituitary-adrenal axis
    • NEUMANN, I.D. 2002. Involvement of the brain oxytocin system in stress coping: interactions with the hypothalamo-pituitary-adrenal axis. Prog. Brain Res. 139: 147-162.
    • (2002) Prog. Brain Res. , vol.139 , pp. 147-162
    • Neumann, I.D.1
  • 27
    • 0032452028 scopus 로고    scopus 로고
    • Steroid hormone regulation of vasopressinergic neurotransmission in the central nervous system
    • WATTERS, J.J., P. POULIN & D.M. DORSA. 1998. Steroid hormone regulation of vasopressinergic neurotransmission in the central nervous system. Prog. Brain Res. 119: 247-261.
    • (1998) Prog. Brain Res. , vol.119 , pp. 247-261
    • Watters, J.J.1    Poulin, P.2    Dorsa, D.M.3
  • 28
    • 0034612234 scopus 로고    scopus 로고
    • Recombinant human relaxin in the treatment of scleroderma. A randomized, double-blind, placebo-controlled trial
    • SEIBOLD, J.R., J.H. KORN, R. SIMMS, et al. 2000. Recombinant human relaxin in the treatment of scleroderma. A randomized, double-blind, placebo-controlled trial. Ann. Intern. Med. 132: 871-879.
    • (2000) Ann. Intern. Med. , vol.132 , pp. 871-879
    • Seibold, J.R.1    Korn, J.H.2    Simms, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.