-
1
-
-
0037442176
-
Long-term survival and transplantation of haemopoietic stem cells for immunodeficiencies: Report of the European experience 1968-99
-
Antoine, C., et al. 2003. Long-term survival and transplantation of haemopoietic stem cells for immunodeficiencies: report of the European experience 1968-99. Lancet. 361:553-560.
-
(2003)
Lancet
, vol.361
, pp. 553-560
-
-
Antoine, C.1
-
2
-
-
0033580206
-
Hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency
-
Buckley, R.H., et al. 1999. Hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency. N. Engl. J. Med. 340:508-516.
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 508-516
-
-
Buckley, R.H.1
-
3
-
-
0034604048
-
Thymic function after hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency
-
Patel, D.D., et al. 2000. Thymic function after hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency. N. Engl. J. Med. 342:1325-1332.
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 1325-1332
-
-
Patel, D.D.1
-
4
-
-
0031593688
-
T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates
-
Kohn, D.B., et al. 1998. T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA- deficient SCID neonates. Nat. Med. 4:775-780.
-
(1998)
Nat. Med.
, vol.4
, pp. 775-780
-
-
Kohn, D.B.1
-
5
-
-
0034724857
-
Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease
-
Cavazzana-Calvo, M., et al. 2000. Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease. Science. 288:669-672.
-
(2000)
Science
, vol.288
, pp. 669-672
-
-
Cavazzana-Calvo, M.1
-
6
-
-
0037189401
-
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning
-
Aiuti, A., et al. 2002. Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning. Science. 296:2410-2413.
-
(2002)
Science
, vol.296
, pp. 2410-2413
-
-
Aiuti, A.1
-
7
-
-
19944421384
-
Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector
-
Gaspar, H.B., et al. 2004, Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector. Lancet. 364:2181-2187.
-
(2004)
Lancet
, vol.364
, pp. 2181-2187
-
-
Gaspar, H.B.1
-
8
-
-
0029902033
-
Spontaneous in vivo reversion to normal of an inherited mutation in a patient with adenosine deaminase deficiency
-
Hitschhorn, R., et al. 1996. Spontaneous in vivo reversion to normal of an inherited mutation in a patient with adenosine deaminase deficiency. Nat. Genet. 13:290-295.
-
(1996)
Nat. Genet.
, vol.13
, pp. 290-295
-
-
Hitschhorn, R.1
-
9
-
-
12944284582
-
Diversity, functionality, and stability of the T cell repertoire derived in vivo from a single human T cell precursor
-
Bousso, P., et al. 2000. Diversity, functionality, and stability of the T cell repertoire derived in vivo from a single human T cell precursor. Proc. Natl. Acad. Sci. U. S. A. 97:274-278.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 274-278
-
-
Bousso, P.1
-
10
-
-
10544244162
-
Atypical X-linked severe combined immunodeficiency due to possible spontaneous reversion of the genetic defect in T cells
-
Stephan, V., et al. 1996. Atypical X-linked severe combined immunodeficiency due to possible spontaneous reversion of the genetic defect in T cells. N. Engl. J. Med. 335:1563-1567.
-
(1996)
N. Engl. J. Med.
, vol.335
, pp. 1563-1567
-
-
Stephan, V.1
-
11
-
-
0035353160
-
T-cell lines from 2 patients with adenosine deaminase (ADA) deficiency showed the restoration of ADA activity resulted from the reversion of an inherited mutation
-
Ariga, T., et al. 2001. T-cell lines from 2 patients with adenosine deaminase (ADA) deficiency showed the restoration of ADA activity resulted from the reversion of an inherited mutation. Blood. 97:2896-2899.
-
(2001)
Blood
, vol.97
, pp. 2896-2899
-
-
Ariga, T.1
-
12
-
-
0003254810
-
Correction of SCID-XI disease phenotype following gc gene transfer by a retroviral vector into CD34+ cells in two children
-
Cavazzana-Calvo, M., et al. 1999. Correction of SCID-XI disease phenotype following gc gene transfer by a retroviral vector into CD34+ cells in two children [abstract]. Blood. 94(Suppl. 1):367a.
-
(1999)
Blood
, vol.94
, Issue.SUPPL. 1
-
-
Cavazzana-Calvo, M.1
-
13
-
-
0036675793
-
Gene therapy of severe combined immunodeficiencies
-
Fischer, A., Hacein-Bey, S., and Cavazzana-Calvo, M. 2002. Gene therapy of severe combined immunodeficiencies. Nat. Rev. Immunol. 2:615-621.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 615-621
-
-
Fischer, A.1
Hacein-Bey, S.2
Cavazzana-Calvo, M.3
-
14
-
-
0037448352
-
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
-
Hacein-Bey-Abina, S., et al. 2003. A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N. Engl. J. Med. 348:255-256.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 255-256
-
-
Hacein-Bey-Abina, S.1
-
15
-
-
0037134031
-
Murine leukemia induced by retroviral gene marking
-
Li, Z., et al. 2002. Murine leukemia induced by retroviral gene marking. Science. 296:497.
-
(2002)
Science
, vol.296
, pp. 497
-
-
Li, Z.1
-
16
-
-
0038819053
-
In vivo administration of a lentiviral vaccine Targets DCs and induces efficient CD8(+) T cell responses
-
doi:10.1172/JCI200317098
-
Esslinger, C., et al. 2003. In vivo administration of a lentiviral vaccine Targets DCs and induces efficient CD8(+) T cell responses. J. Clin. Invest. 111:1673-1681. doi:10.1172/JCI200317098.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 1673-1681
-
-
Esslinger, C.1
-
17
-
-
0036682975
-
Lentiviral vectors containing the human immunodeficiency virus type-1 central polypurine tract can efficiently transduce nondividing hepatocytes and antigen-presenting cells in vivo
-
VandenDriessche, T., et al. 2002. Lentiviral vectors containing the human immunodeficiency virus type-1 central polypurine tract can efficiently transduce nondividing hepatocytes and antigen-presenting cells in vivo. Blood. 100:813-822.
-
(2002)
Blood
, vol.100
, pp. 813-822
-
-
Vandendriessche, T.1
-
18
-
-
0141679049
-
Treatment of canine cyclic neutropenia by lentivirus-mediated G-CSF delivery
-
Yanay, O., et al. 2003, Treatment of canine cyclic neutropenia by lentivirus-mediated G-CSF delivery. Blood. 102:2046-2052.
-
(2003)
Blood
, vol.102
, pp. 2046-2052
-
-
Yanay, O.1
-
19
-
-
0036813389
-
The use of HLA class I tetramers to design a vaccination strategy for melanoma patients
-
Palmowski, M., Salio, M., Dunbar, R.P., and Cerundolo, V. 2002. The use of HLA class I tetramers to design a vaccination strategy for melanoma patients. Immunol. Rev. 188:155-163.
-
(2002)
Immunol. Rev.
, vol.188
, pp. 155-163
-
-
Palmowski, M.1
Salio, M.2
Dunbar, R.P.3
Cerundolo, V.4
-
20
-
-
0142042481
-
Correction of the dystrophic phenotype by in vivo targeting of muscle progenitor cells
-
Kobinger, G.P., Louboutin, J.P., Barton, E.R., Sweeney, H.L., and Wilson, J.M. 2003. Correction of the dystrophic phenotype by in vivo targeting of muscle progenitor cells. Hum. Gene Ther. 14:1441-1449.
-
(2003)
Hum. Gene Ther.
, vol.14
, pp. 1441-1449
-
-
Kobinger, G.P.1
Louboutin, J.P.2
Barton, E.R.3
Sweeney, H.L.4
Wilson, J.M.5
-
21
-
-
0242382679
-
Optimized lentiviral vector production and purification procedure prevents immune response after transduction of mouse brain
-
Baekelandt, V., Eggermont, K., Michiels, M., Nuttin, B., and Debyser, Z. 2003. Optimized lentiviral vector production and purification procedure prevents immune response after transduction of mouse brain. Gene Ther. 10:1933-1940.
-
(2003)
Gene Ther.
, vol.10
, pp. 1933-1940
-
-
Baekelandt, V.1
Eggermont, K.2
Michiels, M.3
Nuttin, B.4
Debyser, Z.5
-
22
-
-
26444493207
-
In situ transduction of stromal cells and thymocytes upon intrathymic injection of lentiviral vectors
-
Marodon, G., and Klatzmann, D. 2004. In situ transduction of stromal cells and thymocytes upon intrathymic injection of lentiviral vectors. BMC Immunol. 5:18.
-
(2004)
BMC Immunol.
, vol.5
, pp. 18
-
-
Marodon, G.1
Klatzmann, D.2
-
23
-
-
0037320932
-
Thymopoiesis independent of common lymphoid progenitors
-
Allman, D., et al. 2003. Thymopoiesis independent of common lymphoid progenitors. Nat. Immunol. 4:168-174.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 168-174
-
-
Allman, D.1
-
24
-
-
0026483786
-
ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
-
Chan, A.C., Iwashima, M., Turck, C.W., and Weiss, A. 1992. ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain. Cell. 71:649-662.
-
(1992)
Cell
, vol.71
, pp. 649-662
-
-
Chan, A.C.1
Iwashima, M.2
Turck, C.W.3
Weiss, A.4
-
25
-
-
0028216232
-
Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling
-
Chan, A.C., et al. 1994. Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling. J. Immunol. 152:4758-4766,
-
(1994)
J. Immunol.
, vol.152
, pp. 4758-4766
-
-
Chan, A.C.1
-
26
-
-
0029133646
-
Essential role for ZAP-70 in both positive and negative selection of thymocytes
-
Negishi, I., et al. 1995. Essential role for ZAP-70 in both positive and negative selection of thymocytes. Nature. 376:435-438.
-
(1995)
Nature
, vol.376
, pp. 435-438
-
-
Negishi, I.1
-
27
-
-
0030802186
-
A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development
-
Wiest, D.L., et al. 1997. A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development. Immunity. 6:663-671.
-
(1997)
Immunity
, vol.6
, pp. 663-671
-
-
Wiest, D.L.1
-
28
-
-
0032211059
-
Differential requirements for ZAP-70 in TCR signaling and T cell development
-
Kadlecek, T.A., et al. 1998. Differential requirements for ZAP-70 in TCR signaling and T cell development. J. Immunol 161:4688-4694.
-
(1998)
J. Immunol
, vol.161
, pp. 4688-4694
-
-
Kadlecek, T.A.1
-
29
-
-
0038542829
-
Specific transgene expression in human and mouse CD4+ cells using lentiviral vectors with regulatory sequences from the CD4gene
-
Marodon, G., et al. 2003. Specific transgene expression in human and mouse CD4+ cells using lentiviral vectors with regulatory sequences from the CD4gene. Blood. 101:3416-3423.
-
(2003)
Blood
, vol.101
, pp. 3416-3423
-
-
Marodon, G.1
-
30
-
-
0141449952
-
Kinetics of steady-state differentiation and mapping of intrathymic-signaling environments by stem cell transplantation in nonirradiated mice
-
Porritt, H.E., Gordon, K., and Petrie, H.T. 2003. Kinetics of steady-state differentiation and mapping of intrathymic-signaling environments by stem cell transplantation in nonirradiated mice. J. Exp. Med. 198:957-962.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 957-962
-
-
Porritt, H.E.1
Gordon, K.2
Petrie, H.T.3
-
31
-
-
0037103385
-
Reconstitution of lymphoid development and function in ZAP-70-deficient mice following gene transfer into bone marrow cells
-
Otsu, M., et al. 2002. Reconstitution of lymphoid development and function in ZAP-70-deficient mice following gene transfer into bone marrow cells. Blood. 100:1248-1256.
-
(2002)
Blood
, vol.100
, pp. 1248-1256
-
-
Otsu, M.1
-
32
-
-
0344304408
-
Turning immunological memory into amnesia by depletion of dividing T cells
-
Bellier, B., Thomas-Vaslin, V., Saron, M.F., and Klatzmann, D. 2003. Turning immunological memory into amnesia by depletion of dividing T cells. Proc. Natl. Acad. Sci. U. S. A. 100:15017-15022,
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 15017-15022
-
-
Bellier, B.1
Thomas-Vaslin, V.2
Saron, M.F.3
Klatzmann, D.4
-
33
-
-
0029884256
-
Restriction of the T-cell repertoire in tumor-infiltrating lymphocytes from nine patients with renal-cell carcinoma. Relevance of the CDR3 length analysis for the identification of in situ clonal T-cell expansions
-
Puisieux, I., et al. l 996. Restriction of the T-cell repertoire in tumor-infiltrating lymphocytes from nine patients with renal-cell carcinoma. Relevance of the CDR3 length analysis for the identification of in situ clonal T-cell expansions. Int. J. Cancer. 66:201-208.
-
(1996)
Int. J. Cancer
, vol.66
, pp. 201-208
-
-
Puisieux, I.1
-
34
-
-
0028908698
-
T-cell repertoire diversity and clonal expansions in normal and clinical samples
-
Pannetier, C., Even, J., and Kourilsky, P. 1995. T-cell repertoire diversity and clonal expansions in normal and clinical samples. Immunol. Today. 16:176-181.
-
(1995)
Immunol. Today
, vol.16
, pp. 176-181
-
-
Pannetier, C.1
Even, J.2
Kourilsky, P.3
-
35
-
-
0031912097
-
Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: Reconstitution studies in a ZAP-70-deficient Jurkat T-cell line
-
Williams, B.L., et al. 1998. Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line. Mol. Cell. Biol. 18:1388-1399.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1388-1399
-
-
Williams, B.L.1
-
36
-
-
0033532628
-
Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes
-
Unutmaz, D., KewalRamani, V.N., Marmon, S., and Littman, D.R. 1999. Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes. J. Exp. Med. 189:1735-1746.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1735-1746
-
-
Unutmaz, D.1
Kewalramani, V.N.2
Marmon, S.3
Littman, D.R.4
-
37
-
-
0142209189
-
In vivo reversion to normal of inherited mutations in humans
-
Hirschhorn, R. 2003. In vivo reversion to normal of inherited mutations in humans. J. Med. Genet. 40:721-728.
-
(2003)
J. Med. Genet.
, vol.40
, pp. 721-728
-
-
Hirschhorn, R.1
-
38
-
-
0033229710
-
Restoration of lymphoid populations in a murine model of X-linked severe combined immunodeficiency by a gene-therapy approach
-
Lo, M., et al. 1999. Restoration of lymphoid populations in a murine model of X-linked severe combined immunodeficiency by a gene-therapy approach. Blood. 94:3027-3036.
-
(1999)
Blood
, vol.94
, pp. 3027-3036
-
-
Lo, M.1
-
39
-
-
0034138030
-
Lymphoid development and function in X-linked severe combined immunodeficiency mice after stem cell gene therapy
-
Otsu, M., et al. 2000. Lymphoid development and function in X-linked severe combined immunodeficiency mice after stem cell gene therapy. Mol. Ther. 1:145-153.
-
(2000)
Mol. Ther.
, vol.1
, pp. 145-153
-
-
Otsu, M.1
-
40
-
-
0033839072
-
Retrovirus-mediated transduction of primary ZAP-70-deficient human T cells results in the selective growth advantage of gene-corrected cells: Implications for gene therapy
-
Steinberg, M., et al. 2000. Retrovirus-mediated transduction of primary ZAP-70-deficient human T cells results in the selective growth advantage of gene-corrected cells: implications for gene therapy. Gene Ther. 7:1392-1400.
-
(2000)
Gene Ther.
, vol.7
, pp. 1392-1400
-
-
Steinberg, M.1
-
41
-
-
0028095020
-
A general method for the generation of high-titer, pantropic retroviral vectors: Highly efficient infection of primary hepatocytes
-
Yee, J.K., et al. 1994. A general method for the generation of high-titer, pantropic retroviral vectors: highly efficient infection of primary hepatocytes. Proc. Natl. Acad. Sci. U. S. A. 91:9564-9568.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 9564-9568
-
-
Yee, J.K.1
-
42
-
-
0035979267
-
IL-7 differentially regulates cell cycle progression and HIV-1-based vector infection in neonatal and adult CD4+ T cells
-
Dardalhon, V., et al. 2001. IL-7 differentially regulates cell cycle progression and HIV-1-based vector infection in neonatal and adult CD4+ T cells. Proc. Natl. Acad. Sci. U. S. A. 98:9277-9282.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 9277-9282
-
-
Dardalhon, V.1
-
43
-
-
0027251463
-
The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments
-
Pannetier, C., et al. 1993. The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments. Proc. Natl. Acad. Sci. U. S. A. 90:4319-4323.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 4319-4323
-
-
Pannetier, C.1
-
44
-
-
0026793582
-
Molecular detection and in vivo analysis of the specific T cell response to a protein antigen
-
Cochet, M., et al. 1992. Molecular detection and in vivo analysis of the specific T cell response to a protein antigen. Eur. J. Immunol. 22:2639-2647.
-
(1992)
Eur. J. Immunol.
, vol.22
, pp. 2639-2647
-
-
Cochet, M.1
-
45
-
-
0029557542
-
Human T-cell receptor variable gene segment families
-
Arden, B., Clark, S.P., Kabelitz, D., and Mak, T.W. 1995. Human T-cell receptor variable gene segment families. Immunogenetics. 42:455-500.
-
(1995)
Immunogenetics
, vol.42
, pp. 455-500
-
-
Arden, B.1
Clark, S.P.2
Kabelitz, D.3
Mak, T.W.4
|