-
1
-
-
0038516689
-
Antibody therapy for rheumatoid arthritis
-
Taylor PC. Antibody therapy for rheumatoid arthritis. Curr Opin Pharmacol 2003;3:323-8.
-
(2003)
Curr Opin Pharmacol
, vol.3
, pp. 323-328
-
-
Taylor, P.C.1
-
2
-
-
0141680246
-
CD154 transcriptional regulation in primary human CD4 T cells
-
Cron RQ. CD154 transcriptional regulation in primary human CD4 T cells. Immunol Res 2003;27:185-202.
-
(2003)
Immunol Res
, vol.27
, pp. 185-202
-
-
Cron, R.Q.1
-
3
-
-
0034810412
-
Regulation of CD40 ligand expression in systemic lupus erythematosus
-
Crow MK, Kirou KA. Regulation of CD40 ligand expression in systemic lupus erythematosus. Curr Opin Rheumatol 2001;13: 361-9.
-
(2001)
Curr Opin Rheumatol
, vol.13
, pp. 361-369
-
-
Crow, M.K.1
Kirou, K.A.2
-
4
-
-
0030870889
-
CD40-CD40 ligand interaction in autoimmune disease
-
Datta SK, Kalled SL. CD40-CD40 ligand interaction in autoimmune disease [review]. Arthritis Rheum 1997;40:1735-45.
-
(1997)
Arthritis Rheum
, vol.40
, pp. 1735-1745
-
-
Datta, S.K.1
Kalled, S.L.2
-
5
-
-
1942505738
-
Costimulation blockade in the treatment of rheumatic diseases
-
Liossis SN, Sfikakis PP. Costimulation blockade in the treatment of rheumatic diseases. BioDrugs 2004;18:95-102.
-
(2004)
BioDrugs
, vol.18
, pp. 95-102
-
-
Liossis, S.N.1
Sfikakis, P.P.2
-
6
-
-
12344336336
-
The role of CD40-CD154 interactions in autoimmunity and the benefit of disrupting this pathway
-
Toubi E, Shoenfeld Y. The role of CD40-CD154 interactions in autoimmunity and the benefit of disrupting this pathway. Autoimmunity 2004;37:457-64.
-
(2004)
Autoimmunity
, vol.37
, pp. 457-464
-
-
Toubi, E.1
Shoenfeld, Y.2
-
7
-
-
0036275436
-
Costimulatory blockade in patients with rheumatoid arthritis: A pilot, dose-finding, double-blind, placebo-controlled clinical trial evaluating CTLA-4Ig and LEA29Y eighty-five days after the first infusion
-
Moreland LW, Alten R, van den Bosch F, Appelboom T, Leon M, Emery P, et al. Costimulatory blockade in patients with rheumatoid arthritis: a pilot, dose-finding, double-blind, placebo-controlled clinical trial evaluating CTLA-4Ig and LEA29Y eighty-five days after the first infusion. Arthritis Rheum 2002;46:1470-9.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 1470-1479
-
-
Moreland, L.W.1
Alten, R.2
Van Den Bosch, F.3
Appelboom, T.4
Leon, M.5
Emery, P.6
-
8
-
-
0242574700
-
Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig
-
Kremer JM, Westhovens R, Leon M, di Giorgio E, Alten R, Steinfeld S, et al. Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig. N Engl J Med 2003;349:1907-15.
-
(2003)
N Engl J Med
, vol.349
, pp. 1907-1915
-
-
Kremer, J.M.1
Westhovens, R.2
Leon, M.3
Di Giorgio, E.4
Alten, R.5
Steinfeld, S.6
-
9
-
-
23644455857
-
Treatment of rheumatoid arthritis with the selective costimulation modulator abatacept: Twelve-month results of a phase lib, double-blind, randomized, placebo-controlled trial
-
Kremer JM, Dougados M, Emery P, Durez P, Sibilia J, Shergy W, et al. Treatment of rheumatoid arthritis with the selective costimulation modulator abatacept: twelve-month results of a phase lib, double-blind, randomized, placebo-controlled trial. Arthritis Rheum 2005;52:2263-71.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2263-2271
-
-
Kremer, J.M.1
Dougados, M.2
Emery, P.3
Durez, P.4
Sibilia, J.5
Shergy, W.6
-
10
-
-
0036852242
-
When ligand becomes receptor: Tolerance via B7 signaling on DCs
-
Finger EB, Bluestone JA. When ligand becomes receptor: tolerance via B7 signaling on DCs. Nat Immunol 2002;3:1056-7.
-
(2002)
Nat Immunol
, vol.3
, pp. 1056-1057
-
-
Finger, E.B.1
Bluestone, J.A.2
-
11
-
-
0023811772
-
Phenotypic analysis of synovial tissue and peripheral blood lymphocytes isolated from patients with rheumatoid arthritis
-
Cush JJ, Lipsky PE. Phenotypic analysis of synovial tissue and peripheral blood lymphocytes isolated from patients with rheumatoid arthritis. Arthritis Rheum 1988;31:1230-8.
-
(1988)
Arthritis Rheum
, vol.31
, pp. 1230-1238
-
-
Cush, J.J.1
Lipsky, P.E.2
-
13
-
-
0035059417
-
Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation
-
Salomon B, Bluestone JA. Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation. Annu Rev Immunol 2001;19:225-52.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 225-252
-
-
Salomon, B.1
Bluestone, J.A.2
-
14
-
-
0023390431
-
Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones
-
Jenkins MK, Pardoll DM, Mizuguchi J, Chused TM, Schwartz RH. Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones. Proc Natl Acad Sci U S A 1987;84:5409-13.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 5409-5413
-
-
Jenkins, M.K.1
Pardoll, D.M.2
Mizuguchi, J.3
Chused, T.M.4
Schwartz, R.H.5
-
15
-
-
0742288423
-
Make or break for costimulatory blockers
-
Garber K. Make or break for costimulatory blockers. Nat Biotechnol 2004;22:145-7.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 145-147
-
-
Garber, K.1
-
17
-
-
2942733370
-
CTLA4Ig: A novel inhibitor of costimulation
-
Dall'Era M, Davis J. CTLA4Ig: a novel inhibitor of costimulation. Lupus 2004;13:372-6.
-
(2004)
Lupus
, vol.13
, pp. 372-376
-
-
Dall'Era, M.1
Davis, J.2
-
18
-
-
0034658408
-
Structural analysis of CTLA-4 function in vivo
-
Masteller EL, Chuang E, Mullen AC, Reiner SL, Thompson CB. Structural analysis of CTLA-4 function in vivo. J Immunol 2000; 164:5319-27.
-
(2000)
J Immunol
, vol.164
, pp. 5319-5327
-
-
Masteller, E.L.1
Chuang, E.2
Mullen, A.C.3
Reiner, S.L.4
Thompson, C.B.5
-
19
-
-
6944222039
-
CTLA-4: Acting at the synapse
-
Chikuma S, Bluestone JA. CTLA-4: acting at the synapse. Mol Interv 2002;2:205-8.
-
(2002)
Mol Interv
, vol.2
, pp. 205-208
-
-
Chikuma, S.1
Bluestone, J.A.2
-
20
-
-
0034823168
-
Signaling through CD28 and CTLA-4 controls two distinct forms of T cell anergy
-
Wells AD, Walsh MC, Bluestone JA, Turka LA. Signaling through CD28 and CTLA-4 controls two distinct forms of T cell anergy. J Clin Invest 2001;108:895-903.
-
(2001)
J Clin Invest
, vol.108
, pp. 895-903
-
-
Wells, A.D.1
Walsh, M.C.2
Bluestone, J.A.3
Turka, L.A.4
-
21
-
-
0032545452
-
Molecular basis of T cell inactivation by CTLA-4
-
Lee KM, Chuang E, Griffin M, Khattri R, Hong DK, Zhang W, et al. Molecular basis of T cell inactivation by CTLA-4. Science 1998;282:2263-6.
-
(1998)
Science
, vol.282
, pp. 2263-2266
-
-
Lee, K.M.1
Chuang, E.2
Griffin, M.3
Khattri, R.4
Hong, D.K.5
Zhang, W.6
-
22
-
-
0030707866
-
Cytotoxic T lymphocyte antigen 4 (CTLA-4) interferes with extracellular signal-regulated kinase (ERK) and Jun NH2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor ζ and ZAP70
-
Calvo CR, Amsen D, Kruisbeek AM. Cytotoxic T lymphocyte antigen 4 (CTLA-4) interferes with extracellular signal-regulated kinase (ERK) and Jun NH2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor ζ and ZAP70. J Exp Med 1997;186:1645-53.
-
(1997)
J Exp Med
, vol.186
, pp. 1645-1653
-
-
Calvo, C.R.1
Amsen, D.2
Kruisbeek, A.M.3
-
23
-
-
0036852170
-
CTLA-4-Ig regulates tryptophan catabolism in vivo
-
Grohmann U, Orabona C, Fallarino F, Vacca C, Calcinaro F, Falorni A, et al. CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat Immunol 2002;3:1097-101.
-
(2002)
Nat Immunol
, vol.3
, pp. 1097-1101
-
-
Grohmann, U.1
Orabona, C.2
Fallarino, F.3
Vacca, C.4
Calcinaro, F.5
Falorni, A.6
-
24
-
-
0026738641
-
Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4Ig
-
Lensehow DJ, Zeng Y, Thistlethwaite JR, Montag A, Brady W, Gibson MG, et al. Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4Ig. Science 1992;257:789-92.
-
(1992)
Science
, vol.257
, pp. 789-792
-
-
Lensehow, D.J.1
Zeng, Y.2
Thistlethwaite, J.R.3
Montag, A.4
Brady, W.5
Gibson, M.G.6
-
25
-
-
0026778697
-
Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule
-
Linsley PS, Wallace PM, Johnson J, Gibson MG, Greene JL, Ledbetter JA, et al. Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule. Science 1992;257:792-5.
-
(1992)
Science
, vol.257
, pp. 792-795
-
-
Linsley, P.S.1
Wallace, P.M.2
Johnson, J.3
Gibson, M.G.4
Greene, J.L.5
Ledbetter, J.A.6
-
26
-
-
0028483990
-
Treatment of murine lupus with CTLA4Ig
-
Finck BK, Linsley PS, Wofsy D. Treatment of murine lupus with CTLA4Ig. Science 1994;265:1225-7.
-
(1994)
Science
, vol.265
, pp. 1225-1227
-
-
Finck, B.K.1
Linsley, P.S.2
Wofsy, D.3
-
27
-
-
0028900297
-
Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse
-
Lenschow DJ, Ho SC, Sattar H, Rhee L, Gray G, Nabavi N, et al. Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse. J Exp Med 1995;181:1145-55.
-
(1995)
J Exp Med
, vol.181
, pp. 1145-1155
-
-
Lenschow, D.J.1
Ho, S.C.2
Sattar, H.3
Rhee, L.4
Gray, G.5
Nabavi, N.6
-
28
-
-
0028868424
-
CD28-B7 costimulatory blockade by CTLA4Ig prevents actively induced experimental autoimmune encephalomyelitis and inhibits Th1 but spares Th2 cytokines in the central nervous system
-
Khoury SJ, Akalin E, Chandraker A, Turka LA, Linsley PS, Sayegh MH, et al. CD28-B7 costimulatory blockade by CTLA4Ig prevents actively induced experimental autoimmune encephalomyelitis and inhibits Th1 but spares Th2 cytokines in the central nervous system. J Immunol 1995;155:4521-4.
-
(1995)
J Immunol
, vol.155
, pp. 4521-4524
-
-
Khoury, S.J.1
Akalin, E.2
Chandraker, A.3
Turka, L.A.4
Linsley, P.S.5
Sayegh, M.H.6
-
29
-
-
0029849012
-
Prevention and amelioration of collagen-induced arthritis by blockade of the CD28 co-stimulatory pathway: Requirement for both B7-1 and B7-2
-
Webb LM, Walmsley MJ, Feldmann M. Prevention and amelioration of collagen-induced arthritis by blockade of the CD28 co-stimulatory pathway: requirement for both B7-1 and B7-2. Eur J Immunol 1996;26:2320-8.
-
(1996)
Eur J Immunol
, vol.26
, pp. 2320-2328
-
-
Webb, L.M.1
Walmsley, M.J.2
Feldmann, M.3
-
30
-
-
0032126158
-
Immunotherapy of experimental autoimmune myasthenia gravis: Selective effects of CTLA4Ig and synergistic combination with an IL2-diphtheria toxin fusion protein
-
McIntosh KR, Linsley PS, Bacha PA, Drachman DB. Immunotherapy of experimental autoimmune myasthenia gravis: selective effects of CTLA4Ig and synergistic combination with an IL2-diphtheria toxin fusion protein. J Neuroimmunol 1998;87:136-46.
-
(1998)
J Neuroimmunol
, vol.87
, pp. 136-146
-
-
McIntosh, K.R.1
Linsley, P.S.2
Bacha, P.A.3
Drachman, D.B.4
-
31
-
-
0036513699
-
Blockade of T cell costimulatory signals using adenovirus vectors prevents both the induction and the progression of experimental autoimmune myocarditis
-
Matsui Y, Inobe M, Okamoto H, Chiba S, Shimizu T, Kitabatake A, et al. Blockade of T cell costimulatory signals using adenovirus vectors prevents both the induction and the progression of experimental autoimmune myocarditis. J Mol Cell Cardiol 2002;34: 279-95.
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 279-295
-
-
Matsui, Y.1
Inobe, M.2
Okamoto, H.3
Chiba, S.4
Shimizu, T.5
Kitabatake, A.6
-
32
-
-
0035284737
-
Cutting edge: Reversal of murine lupus nephritis with CTLA4Ig and cyclophosphamide
-
Daikh DI, Wofsy D. Cutting edge: reversal of murine lupus nephritis with CTLA4Ig and cyclophosphamide. J Immunol 2001; 166:2913-6.
-
(2001)
J Immunol
, vol.166
, pp. 2913-2916
-
-
Daikh, D.I.1
Wofsy, D.2
-
33
-
-
0031307384
-
Immunosuppressive effects of human CTLA4Ig in a non-human primate model of allogeneic pancreatic islet transplantation
-
Levisetti MG, Padrid PA, Szot GL, Mittal N, Meehan SM, Wardrip CL, et al. Immunosuppressive effects of human CTLA4Ig in a non-human primate model of allogeneic pancreatic islet transplantation. J Immunol 1997;159:5187-91.
-
(1997)
J Immunol
, vol.159
, pp. 5187-5191
-
-
Levisetti, M.G.1
Padrid, P.A.2
Szot, G.L.3
Mittal, N.4
Meehan, S.M.5
Wardrip, C.L.6
-
34
-
-
0033135564
-
CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris
-
Abrams JR, Lebwohl MG, Guzzo CA, Jegasothy BV, Goldfarb MT, Goffe BS, et al. CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris. J Clin Invest 1999;103:1243-52.
-
(1999)
J Clin Invest
, vol.103
, pp. 1243-1252
-
-
Abrams, J.R.1
Lebwohl, M.G.2
Guzzo, C.A.3
Jegasothy, B.V.4
Goldfarb, M.T.5
Goffe, B.S.6
-
35
-
-
0029044362
-
American College of Rheumatology preliminary definition of improvement in rheumatoid arthritis
-
Felson DT, Anderson JJ, Boers M, Bombardier C, Furst D, Goldsmith C, et al. American College of Rheumatology preliminary definition of improvement in rheumatoid arthritis. Arthritis Rheum 1995;38:727-35.
-
(1995)
Arthritis Rheum
, vol.38
, pp. 727-735
-
-
Felson, D.T.1
Anderson, J.J.2
Boers, M.3
Bombardier, C.4
Furst, D.5
Goldsmith, C.6
-
36
-
-
0021046385
-
Assessment of patient satisfaction in activities of daily living using a modified Stanford Health Assessment Questionnaire
-
Pincus T, Summey JA, Soraci SA Jr, Wallston KA, Hummon NP. Assessment of patient satisfaction in activities of daily living using a modified Stanford Health Assessment Questionnaire. Arthritis Rheum 1983;26:1346-53.
-
(1983)
Arthritis Rheum
, vol.26
, pp. 1346-1353
-
-
Pincus, T.1
Summey, J.A.2
Soraci Jr., S.A.3
Wallston, K.A.4
Hummon, N.P.5
-
37
-
-
0031660364
-
Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor α monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis
-
Maini RN, Breedveld FC, Kalden JR, Smolen JS, Davis D, Macfarlane JD, et al. Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor α monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum 1998;41:1552-63.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 1552-1563
-
-
Maini, R.N.1
Breedveld, F.C.2
Kalden, J.R.3
Smolen, J.S.4
Davis, D.5
Macfarlane, J.D.6
-
38
-
-
0037231533
-
Adalimumab, a fully human anti-tumor necrosis factor α monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: The ARMADA trial
-
Weinblatt ME, Keystone EC, Furst DE, Moreland LW, Weisman MH, Birbara CA, et al. Adalimumab, a fully human anti-tumor necrosis factor α monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trial. Arthritis Rheum 2003;48:35-45.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 35-45
-
-
Weinblatt, M.E.1
Keystone, E.C.2
Furst, D.E.3
Moreland, L.W.4
Weisman, M.H.5
Birbara, C.A.6
-
39
-
-
0033611472
-
A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate
-
Weinblatt ME, Kremer JM, Bankhurst AD, Bulpitt KJ, Fleischmann RM, Fox RI, et al. A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. N Engl J Med 1999; 340:253-9.
-
(1999)
N Engl J Med
, vol.340
, pp. 253-259
-
-
Weinblatt, M.E.1
Kremer, J.M.2
Bankhurst, A.D.3
Bulpitt, K.J.4
Fleischmann, R.M.5
Fox, R.I.6
-
40
-
-
2542418988
-
Cytotoxic T-lymphocyte antigen 4-immunoglobulin in rheumatoid arthritis
-
Kremer JM. Cytotoxic T-lymphocyte antigen 4-immunoglobulin in rheumatoid arthritis. Rheum Dis Clin North Am 2004;30:381-91.
-
(2004)
Rheum Dis Clin North Am
, vol.30
, pp. 381-391
-
-
Kremer, J.M.1
|