SCOPUS 정보 검색 플랫폼

Organic and Biomolecular Chemistry

Volumn 2, Issue 7, 2004, Pages 1077-1085

Direct catalytic asymmetric aldol reactions of pyruvates: Scope and mechanism

(5) Gathergood, Nicholas a,b Juhl, Karsten a Poulsen, Thomas B a Thordrup, Karl a Jørgensen, Karl Anker a

a AARHUS UNIVERSITY (Denmark)

b MONASH UNIVERSITY (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; CARBON; CATALYSIS; ENZYMES; ETHERS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION KINETICS; SYNTHESIS (CHEMICAL);

ALDOL REACTION; CROSS-ALDOL ADDUCTS; ORGANOCATALYSIS; REACTION MIXTURES;

BIOCHEMISTRY;

HOMO;

EID: 2342646154 PISSN: 14770520 EISSN: None Source Type: Journal
DOI: 10.1039/b316092k Document Type: Article

Times cited : (74)

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43
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57
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77
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- Catalytic enantioselective hetero-Diels-Alder reactions, see e.g.: (a) M. Johannsen and K. A. Jørgensen, J. Org. Chem., 1995, 60, 5757; (b) M. Johannsen and K. A. Jørgensen, Tetrahedron, 1996, 52, 7321; (c) M. Johannsen and K. A. Jørgensen, J. Chem. Soc., Perkin Trans. 2, 1997, 1183; (d) M. Johannsen, S. Yao and K. A. Jørgensen, Chem. Commun., 1997, 2169; (e) S. Yao, M. Johannsen, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 1998, 63, 118; (f) S. Yao, M. Johannsen, H. Audrain, R. G. Hazell and K. A. Jørgensen, J. Am. Chem. Soc., 1998, 120, 8599; (g) A. K. Ghosh, P. Mathivanan, J. Cappiello and K. Krishnan, Tetrahedron: Asymmetry, 1996, 7, 2165; (h) J. Thorhauge, M. Johannsen and K. A. Jørgensen, Angew. Chem., Int. Ed., 1998, 37, 2404; (i) D. A. Evans, E. J. Olhava, J. S. Johnson and J. M. Janey, Angew. Chem., Int. Ed., 1998, 37, 3372; (j) D. A. Evans, J. S. Johnson and E. J. Olhava, J. Am. Chem. Soc., 2000, 122, 1635; (k) H. Audrain, J. Thorhauge, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 2000, 65, 4487; (l) W. Zhuang, J. Thorhauge and K. A. Jørgensen, Chem. Commun., 2000, 459.
- (1996) Tetrahedron , vol.52 , pp. 7321
- Johannsen, M.¹ Jørgensen, K.A.²

78
- 0347768768
- Catalytic enantioselective hetero-Diels-Alder reactions, see e.g.: (a) M. Johannsen and K. A. Jørgensen, J. Org. Chem., 1995, 60, 5757; (b) M. Johannsen and K. A. Jørgensen, Tetrahedron, 1996, 52, 7321; (c) M. Johannsen and K. A. Jørgensen, J. Chem. Soc., Perkin Trans. 2, 1997, 1183; (d) M. Johannsen, S. Yao and K. A. Jørgensen, Chem. Commun., 1997, 2169; (e) S. Yao, M. Johannsen, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 1998, 63, 118; (f) S. Yao, M. Johannsen, H. Audrain, R. G. Hazell and K. A. Jørgensen, J. Am. Chem. Soc., 1998, 120, 8599; (g) A. K. Ghosh, P. Mathivanan, J. Cappiello and K. Krishnan, Tetrahedron: Asymmetry, 1996, 7, 2165; (h) J. Thorhauge, M. Johannsen and K. A. Jørgensen, Angew. Chem., Int. Ed., 1998, 37, 2404; (i) D. A. Evans, E. J. Olhava, J. S. Johnson and J. M. Janey, Angew. Chem., Int. Ed., 1998, 37, 3372; (j) D. A. Evans, J. S. Johnson and E. J. Olhava, J. Am. Chem. Soc., 2000, 122, 1635; (k) H. Audrain, J. Thorhauge, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 2000, 65, 4487; (l) W. Zhuang, J. Thorhauge and K. A. Jørgensen, Chem. Commun., 2000, 459.
- (1997) J. Chem. Soc., Perkin Trans. , vol.2 , pp. 1183
- Johannsen, M.¹ Jørgensen, K.A.²

79
- 0002816322
- Catalytic enantioselective hetero-Diels-Alder reactions, see e.g.: (a) M. Johannsen and K. A. Jørgensen, J. Org. Chem., 1995, 60, 5757; (b) M. Johannsen and K. A. Jørgensen, Tetrahedron, 1996, 52, 7321; (c) M. Johannsen and K. A. Jørgensen, J. Chem. Soc., Perkin Trans. 2, 1997, 1183; (d) M. Johannsen, S. Yao and K. A. Jørgensen, Chem. Commun., 1997, 2169; (e) S. Yao, M. Johannsen, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 1998, 63, 118; (f) S. Yao, M. Johannsen, H. Audrain, R. G. Hazell and K. A. Jørgensen, J. Am. Chem. Soc., 1998, 120, 8599; (g) A. K. Ghosh, P. Mathivanan, J. Cappiello and K. Krishnan, Tetrahedron: Asymmetry, 1996, 7, 2165; (h) J. Thorhauge, M. Johannsen and K. A. Jørgensen, Angew. Chem., Int. Ed., 1998, 37, 2404; (i) D. A. Evans, E. J. Olhava, J. S. Johnson and J. M. Janey, Angew. Chem., Int. Ed., 1998, 37, 3372; (j) D. A. Evans, J. S. Johnson and E. J. Olhava, J. Am. Chem. Soc., 2000, 122, 1635; (k) H. Audrain, J. Thorhauge, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 2000, 65, 4487; (l) W. Zhuang, J. Thorhauge and K. A. Jørgensen, Chem. Commun., 2000, 459.
- (1997) Chem. Commun. , pp. 2169
- Johannsen, M.¹ Yao, S.² Jørgensen, K.A.³

80
- 0002428308
- Catalytic enantioselective hetero-Diels-Alder reactions, see e.g.: (a) M. Johannsen and K. A. Jørgensen, J. Org. Chem., 1995, 60, 5757; (b) M. Johannsen and K. A. Jørgensen, Tetrahedron, 1996, 52, 7321; (c) M. Johannsen and K. A. Jørgensen, J. Chem. Soc., Perkin Trans. 2, 1997, 1183; (d) M. Johannsen, S. Yao and K. A. Jørgensen, Chem. Commun., 1997, 2169; (e) S. Yao, M. Johannsen, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 1998, 63, 118; (f) S. Yao, M. Johannsen, H. Audrain, R. G. Hazell and K. A. Jørgensen, J. Am. Chem. Soc., 1998, 120, 8599; (g) A. K. Ghosh, P. Mathivanan, J. Cappiello and K. Krishnan, Tetrahedron: Asymmetry, 1996, 7, 2165; (h) J. Thorhauge, M. Johannsen and K. A. Jørgensen, Angew. Chem., Int. Ed., 1998, 37, 2404; (i) D. A. Evans, E. J. Olhava, J. S. Johnson and J. M. Janey, Angew. Chem., Int. Ed., 1998, 37, 3372; (j) D. A. Evans, J. S. Johnson and E. J. Olhava, J. Am. Chem. Soc., 2000, 122, 1635; (k) H. Audrain, J. Thorhauge, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 2000, 65, 4487; (l) W. Zhuang, J. Thorhauge and K. A. Jørgensen, Chem. Commun., 2000, 459.
- (1998) J. Org. Chem. , vol.63 , pp. 118
- Yao, S.¹ Johannsen, M.² Hazell, R.G.³ Jørgensen, K.A.⁴

81
- 0032475445
- Catalytic enantioselective hetero-Diels-Alder reactions, see e.g.: (a) M. Johannsen and K. A. Jørgensen, J. Org. Chem., 1995, 60, 5757; (b) M. Johannsen and K. A. Jørgensen, Tetrahedron, 1996, 52, 7321; (c) M. Johannsen and K. A. Jørgensen, J. Chem. Soc., Perkin Trans. 2, 1997, 1183; (d) M. Johannsen, S. Yao and K. A. Jørgensen, Chem. Commun., 1997, 2169; (e) S. Yao, M. Johannsen, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 1998, 63, 118; (f) S. Yao, M. Johannsen, H. Audrain, R. G. Hazell and K. A. Jørgensen, J. Am. Chem. Soc., 1998, 120, 8599; (g) A. K. Ghosh, P. Mathivanan, J. Cappiello and K. Krishnan, Tetrahedron: Asymmetry, 1996, 7, 2165; (h) J. Thorhauge, M. Johannsen and K. A. Jørgensen, Angew. Chem., Int. Ed., 1998, 37, 2404; (i) D. A. Evans, E. J. Olhava, J. S. Johnson and J. M. Janey, Angew. Chem., Int. Ed., 1998, 37, 3372; (j) D. A. Evans, J. S. Johnson and E. J. Olhava, J. Am. Chem. Soc., 2000, 122, 1635; (k) H. Audrain, J. Thorhauge, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 2000, 65, 4487; (l) W. Zhuang, J. Thorhauge and K. A. Jørgensen, Chem. Commun., 2000, 459.
- (1998) J. Am. Chem. Soc. , vol.120 , pp. 8599
- Yao, S.¹ Johannsen, M.² Audrain, H.³ Hazell, R.G.⁴ Jørgensen, K.A.⁵

82
- 0030220901
- Catalytic enantioselective hetero-Diels-Alder reactions, see e.g.: (a) M. Johannsen and K. A. Jørgensen, J. Org. Chem., 1995, 60, 5757; (b) M. Johannsen and K. A. Jørgensen, Tetrahedron, 1996, 52, 7321; (c) M. Johannsen and K. A. Jørgensen, J. Chem. Soc., Perkin Trans. 2, 1997, 1183; (d) M. Johannsen, S. Yao and K. A. Jørgensen, Chem. Commun., 1997, 2169; (e) S. Yao, M. Johannsen, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 1998, 63, 118; (f) S. Yao, M. Johannsen, H. Audrain, R. G. Hazell and K. A. Jørgensen, J. Am. Chem. Soc., 1998, 120, 8599; (g) A. K. Ghosh, P. Mathivanan, J. Cappiello and K. Krishnan, Tetrahedron: Asymmetry, 1996, 7, 2165; (h) J. Thorhauge, M. Johannsen and K. A. Jørgensen, Angew. Chem., Int. Ed., 1998, 37, 2404; (i) D. A. Evans, E. J. Olhava, J. S. Johnson and J. M. Janey, Angew. Chem., Int. Ed., 1998, 37, 3372; (j) D. A. Evans, J. S. Johnson and E. J. Olhava, J. Am. Chem. Soc., 2000, 122, 1635; (k) H. Audrain, J. Thorhauge, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 2000, 65, 4487; (l) W. Zhuang, J. Thorhauge and K. A. Jørgensen, Chem. Commun., 2000, 459.
- (1996) Tetrahedron: Asymmetry , vol.7 , pp. 2165
- Ghosh, A.K.¹ Mathivanan, P.² Cappiello, J.³ Krishnan, K.⁴

83
- 0032544310
- Catalytic enantioselective hetero-Diels-Alder reactions, see e.g.: (a) M. Johannsen and K. A. Jørgensen, J. Org. Chem., 1995, 60, 5757; (b) M. Johannsen and K. A. Jørgensen, Tetrahedron, 1996, 52, 7321; (c) M. Johannsen and K. A. Jørgensen, J. Chem. Soc., Perkin Trans. 2, 1997, 1183; (d) M. Johannsen, S. Yao and K. A. Jørgensen, Chem. Commun., 1997, 2169; (e) S. Yao, M. Johannsen, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 1998, 63, 118; (f) S. Yao, M. Johannsen, H. Audrain, R. G. Hazell and K. A. Jørgensen, J. Am. Chem. Soc., 1998, 120, 8599; (g) A. K. Ghosh, P. Mathivanan, J. Cappiello and K. Krishnan, Tetrahedron: Asymmetry, 1996, 7, 2165; (h) J. Thorhauge, M. Johannsen and K. A. Jørgensen, Angew. Chem., Int. Ed., 1998, 37, 2404; (i) D. A. Evans, E. J. Olhava, J. S. Johnson and J. M. Janey, Angew. Chem., Int. Ed., 1998, 37, 3372; (j) D. A. Evans, J. S. Johnson and E. J. Olhava, J. Am. Chem. Soc., 2000, 122, 1635; (k) H. Audrain, J. Thorhauge, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 2000, 65, 4487; (l) W. Zhuang, J. Thorhauge and K. A. Jørgensen, Chem. Commun., 2000, 459.
- (1998) Angew. Chem., Int. Ed. , vol.37 , pp. 2404
- Thorhauge, J.¹ Johannsen, M.² Jørgensen, K.A.³

84
- 0033521665
- Catalytic enantioselective hetero-Diels-Alder reactions, see e.g.: (a) M. Johannsen and K. A. Jørgensen, J. Org. Chem., 1995, 60, 5757; (b) M. Johannsen and K. A. Jørgensen, Tetrahedron, 1996, 52, 7321; (c) M. Johannsen and K. A. Jørgensen, J. Chem. Soc., Perkin Trans. 2, 1997, 1183; (d) M. Johannsen, S. Yao and K. A. Jørgensen, Chem. Commun., 1997, 2169; (e) S. Yao, M. Johannsen, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 1998, 63, 118; (f) S. Yao, M. Johannsen, H. Audrain, R. G. Hazell and K. A. Jørgensen, J. Am. Chem. Soc., 1998, 120, 8599; (g) A. K. Ghosh, P. Mathivanan, J. Cappiello and K. Krishnan, Tetrahedron: Asymmetry, 1996, 7, 2165; (h) J. Thorhauge, M. Johannsen and K. A. Jørgensen, Angew. Chem., Int. Ed., 1998, 37, 2404; (i) D. A. Evans, E. J. Olhava, J. S. Johnson and J. M. Janey, Angew. Chem., Int. Ed., 1998, 37, 3372; (j) D. A. Evans, J. S. Johnson and E. J. Olhava, J. Am. Chem. Soc., 2000, 122, 1635; (k) H. Audrain, J. Thorhauge, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 2000, 65, 4487; (l) W. Zhuang, J. Thorhauge and K. A. Jørgensen, Chem. Commun., 2000, 459.
- (1998) Angew. Chem., Int. Ed. , vol.37 , pp. 3372
- Evans, D.A.¹ Olhava, E.J.² Johnson, J.S.³ Janey, J.M.⁴

85
- 0034006954
- Catalytic enantioselective hetero-Diels-Alder reactions, see e.g.: (a) M. Johannsen and K. A. Jørgensen, J. Org. Chem., 1995, 60, 5757; (b) M. Johannsen and K. A. Jørgensen, Tetrahedron, 1996, 52, 7321; (c) M. Johannsen and K. A. Jørgensen, J. Chem. Soc., Perkin Trans. 2, 1997, 1183; (d) M. Johannsen, S. Yao and K. A. Jørgensen, Chem. Commun., 1997, 2169; (e) S. Yao, M. Johannsen, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 1998, 63, 118; (f) S. Yao, M. Johannsen, H. Audrain, R. G. Hazell and K. A. Jørgensen, J. Am. Chem. Soc., 1998, 120, 8599; (g) A. K. Ghosh, P. Mathivanan, J. Cappiello and K. Krishnan, Tetrahedron: Asymmetry, 1996, 7, 2165; (h) J. Thorhauge, M. Johannsen and K. A. Jørgensen, Angew. Chem., Int. Ed., 1998, 37, 2404; (i) D. A. Evans, E. J. Olhava, J. S. Johnson and J. M. Janey, Angew. Chem., Int. Ed., 1998, 37, 3372; (j) D. A. Evans, J. S. Johnson and E. J. Olhava, J. Am. Chem. Soc., 2000, 122, 1635; (k) H. Audrain, J. Thorhauge, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 2000, 65, 4487; (l) W. Zhuang, J. Thorhauge and K. A. Jørgensen, Chem. Commun., 2000, 459.
- (2000) J. Am. Chem. Soc. , vol.122 , pp. 1635
- Evans, D.A.¹ Johnson, J.S.² Olhava, E.J.³

86
- 0034725914
- Catalytic enantioselective hetero-Diels-Alder reactions, see e.g.: (a) M. Johannsen and K. A. Jørgensen, J. Org. Chem., 1995, 60, 5757; (b) M. Johannsen and K. A. Jørgensen, Tetrahedron, 1996, 52, 7321; (c) M. Johannsen and K. A. Jørgensen, J. Chem. Soc., Perkin Trans. 2, 1997, 1183; (d) M. Johannsen, S. Yao and K. A. Jørgensen, Chem. Commun., 1997, 2169; (e) S. Yao, M. Johannsen, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 1998, 63, 118; (f) S. Yao, M. Johannsen, H. Audrain, R. G. Hazell and K. A. Jørgensen, J. Am. Chem. Soc., 1998, 120, 8599; (g) A. K. Ghosh, P. Mathivanan, J. Cappiello and K. Krishnan, Tetrahedron: Asymmetry, 1996, 7, 2165; (h) J. Thorhauge, M. Johannsen and K. A. Jørgensen, Angew. Chem., Int. Ed., 1998, 37, 2404; (i) D. A. Evans, E. J. Olhava, J. S. Johnson and J. M. Janey, Angew. Chem., Int. Ed., 1998, 37, 3372; (j) D. A. Evans, J. S. Johnson and E. J. Olhava, J. Am. Chem. Soc., 2000, 122, 1635; (k) H. Audrain, J. Thorhauge, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 2000, 65, 4487; (l) W. Zhuang, J. Thorhauge and K. A. Jørgensen, Chem. Commun., 2000, 459.
- (2000) J. Org. Chem. , vol.65 , pp. 4487
- Audrain, H.¹ Thorhauge, J.² Hazell, R.G.³ Jørgensen, K.A.⁴

87
- 0034696658
- Catalytic enantioselective hetero-Diels-Alder reactions, see e.g.: (a) M. Johannsen and K. A. Jørgensen, J. Org. Chem., 1995, 60, 5757; (b) M. Johannsen and K. A. Jørgensen, Tetrahedron, 1996, 52, 7321; (c) M. Johannsen and K. A. Jørgensen, J. Chem. Soc., Perkin Trans. 2, 1997, 1183; (d) M. Johannsen, S. Yao and K. A. Jørgensen, Chem. Commun., 1997, 2169; (e) S. Yao, M. Johannsen, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 1998, 63, 118; (f) S. Yao, M. Johannsen, H. Audrain, R. G. Hazell and K. A. Jørgensen, J. Am. Chem. Soc., 1998, 120, 8599; (g) A. K. Ghosh, P. Mathivanan, J. Cappiello and K. Krishnan, Tetrahedron: Asymmetry, 1996, 7, 2165; (h) J. Thorhauge, M. Johannsen and K. A. Jørgensen, Angew. Chem., Int. Ed., 1998, 37, 2404; (i) D. A. Evans, E. J. Olhava, J. S. Johnson and J. M. Janey, Angew. Chem., Int. Ed., 1998, 37, 3372; (j) D. A. Evans, J. S. Johnson and E. J. Olhava, J. Am. Chem. Soc., 2000, 122, 1635; (k) H. Audrain, J. Thorhauge, R. G. Hazell and K. A. Jørgensen, J. Org. Chem., 2000, 65, 4487; (l) W. Zhuang, J. Thorhauge and K. A. Jørgensen, Chem. Commun., 2000, 459.
- (2000) Chem. Commun. , pp. 459
- Zhuang, W.¹ Thorhauge, J.² Jørgensen, K.A.³

88
- 0034706033
- and references therein
- Catalytic enantioselective carbonyl-ene reactions, see eg.: (a) D. A. Evans, S. W. Tregay, C. S. Burgey, N. A. Paras and T. Vojkovsky, J. Am. Chem. Soc., 2000, 122, 7936 and references therein; (b) F. Reichel, X. Fang, S. Yao, M. Ricci and K. A. Jørgensen, Chem. Commun., 1999, 1505; (c) N. Gathergood and K. A. Jørgensen, Chem. Commun., 1999, 1869; (d) D. A. Evans, C. S. Burgey, N. A. Paras, T. Vojkovsky and S. W. Tregay, J. Am. Chem. Soc., 1998, 120, 5824; (e) Y. Gao, P. Lane-Bell and J. C. Vederas, J. Org. Chem., 1998, 63, 2133.
- (2000) J. Am. Chem. Soc. , vol.122 , pp. 7936
- Evans, D.A.¹ Tregay, S.W.² Burgey, C.S.³ Paras, N.A.⁴ Vojkovsky, T.⁵

89
- 0033592231
- Catalytic enantioselective carbonyl-ene reactions, see eg.: (a) D. A. Evans, S. W. Tregay, C. S. Burgey, N. A. Paras and T. Vojkovsky, J. Am. Chem. Soc., 2000, 122, 7936 and references therein; (b) F. Reichel, X. Fang, S. Yao, M. Ricci and K. A. Jørgensen, Chem. Commun., 1999, 1505; (c) N. Gathergood and K. A. Jørgensen, Chem. Commun., 1999, 1869; (d) D. A. Evans, C. S. Burgey, N. A. Paras, T. Vojkovsky and S. W. Tregay, J. Am. Chem. Soc., 1998, 120, 5824; (e) Y. Gao, P. Lane-Bell and J. C. Vederas, J. Org. Chem., 1998, 63, 2133.
- (1999) Chem. Commun. , pp. 1505
- Reichel, F.¹ Fang, X.² Yao, S.³ Ricci, M.⁴ Jørgensen, K.A.⁵

90
- 0033592439
- Catalytic enantioselective carbonyl-ene reactions, see eg.: (a) D. A. Evans, S. W. Tregay, C. S. Burgey, N. A. Paras and T. Vojkovsky, J. Am. Chem. Soc., 2000, 122, 7936 and references therein; (b) F. Reichel, X. Fang, S. Yao, M. Ricci and K. A. Jørgensen, Chem. Commun., 1999, 1505; (c) N. Gathergood and K. A. Jørgensen, Chem. Commun., 1999, 1869; (d) D. A. Evans, C. S. Burgey, N. A. Paras, T. Vojkovsky and S. W. Tregay, J. Am. Chem. Soc., 1998, 120, 5824; (e) Y. Gao, P. Lane-Bell and J. C. Vederas, J. Org. Chem., 1998, 63, 2133.
- (1999) Chem. Commun. , pp. 1869
- Gathergood, N.¹ Jørgensen, K.A.²

91
- 0032540647
- Catalytic enantioselective carbonyl-ene reactions, see eg.: (a) D. A. Evans, S. W. Tregay, C. S. Burgey, N. A. Paras and T. Vojkovsky, J. Am. Chem. Soc., 2000, 122, 7936 and references therein; (b) F. Reichel, X. Fang, S. Yao, M. Ricci and K. A. Jørgensen, Chem. Commun., 1999, 1505; (c) N. Gathergood and K. A. Jørgensen, Chem. Commun., 1999, 1869; (d) D. A. Evans, C. S. Burgey, N. A. Paras, T. Vojkovsky and S. W. Tregay, J. Am. Chem. Soc., 1998, 120, 5824; (e) Y. Gao, P. Lane-Bell and J. C. Vederas, J. Org. Chem., 1998, 63, 2133.
- (1998) J. Am. Chem. Soc. , vol.120 , pp. 5824
- Evans, D.A.¹ Burgey, C.S.² Paras, N.A.³ Vojkovsky, T.⁴ Tregay, S.W.⁵

92
- 0032478649
- Catalytic enantioselective carbonyl-ene reactions, see eg.: (a) D. A. Evans, S. W. Tregay, C. S. Burgey, N. A. Paras and T. Vojkovsky, J. Am. Chem. Soc., 2000, 122, 7936 and references therein; (b) F. Reichel, X. Fang, S. Yao, M. Ricci and K. A. Jørgensen, Chem. Commun., 1999, 1505; (c) N. Gathergood and K. A. Jørgensen, Chem. Commun., 1999, 1869; (d) D. A. Evans, C. S. Burgey, N. A. Paras, T. Vojkovsky and S. W. Tregay, J. Am. Chem. Soc., 1998, 120, 5824; (e) Y. Gao, P. Lane-Bell and J. C. Vederas, J. Org. Chem., 1998, 63, 2133.
- (1998) J. Org. Chem. , vol.63 , pp. 2133
- Gao, Y.¹ Lane-Bell, P.² Vederas, J.C.³

93
- 0042233997
- Catalytic enantioselective Friedel-Crafts reactions see e.g. ref. 16; see also: D. A. Evans, K. A. Scheidt, K. R. Fandrick, H. W. Lam and J. Wu, J. Am. Chem. Soc., 2003, 125, 10780.
- (2003) J. Am. Chem. Soc. , vol.125 , pp. 10780
- Evans, D.A.¹ Scheidt, K.A.² Fandrick, K.R.³ Lam, H.W.⁴ Wu, J.⁵

94
- 0035825178
- Catalytic enantioselective Friedel-Crafts allylation reactions: (a) K. B. Jensen, J. Thorhauge, R. G. Hazell and K. A. Jørgensen, Angew. Chem., Int. Ed., 2001, 40, 160; (b) W. Zhuang, T. Hansen and K. A. Jørgensen, Chem. Commun., 2001, 347.
- (2001) Angew. Chem., Int. Ed. , vol.40 , pp. 160
- Jensen, K.B.¹ Thorhauge, J.² Hazell, R.G.³ Jørgensen, K.A.⁴

95
- 0035925220
- Catalytic enantioselective Friedel-Crafts allylation reactions: (a) K. B. Jensen, J. Thorhauge, R. G. Hazell and K. A. Jørgensen, Angew. Chem., Int. Ed., 2001, 40, 160; (b) W. Zhuang, T. Hansen and K. A. Jørgensen, Chem. Commun., 2001, 347.
- (2001) Chem. Commun. , pp. 347
- Zhuang, W.¹ Hansen, T.² Jørgensen, K.A.³

96
- 0034703753
- Catalytic enantioselective δ-lactone formation reactions: H. Audrain and K. A. Jørgensen, J. Am. Chem. Soc., 2000, 122, 11543.
- (2000) J. Am. Chem. Soc. , vol.122 , pp. 11543
- Audrain, H.¹ Jørgensen, K.A.²

97
- 0035902842
- Catalytic enantioselective direct Mannich reactions: (a) K. Juhl, N. Gathergood and K. A. Jørgensen, Angew. Chem., Int. Ed., 2001, 40, 2995; (b) M. Marigo, A. Kjærsgaard, K. Juhl, N. Gathergood and K. A. Jørgensen, Chem. Eur. J., 2003, 9, 2359.
- (2001) Angew. Chem., Int. Ed. , vol.40 , pp. 2995
- Juhl, K.¹ Gathergood, N.² Jørgensen, K.A.³

98
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