Identification of a negative regulatory cis-element in the enhancer core region of the prostate-specific antigen promoter: Implications for intersection of androgen receptor and nuclear factor-κB signalling in prostate cancer cells

Biochemical Journal

Volumn 379, Issue 2, 2004, Pages 421-431

  Cinar, Bekir ^a,c   Yeung, Fan ^a   Konaka, Hiroyuki ^b   Mayo, Marty W ^a   Freeman, Michael R ^c   Zhau, Haiyen E ^b,d   Chung, Leland W K ^b,d  

^a UNIVERSITY OF VIRGINIA   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d EMORY UNIVERSITY   (United States)

Author keywords

Androgen receptor; Nuclear factor B (NF B); Prostate cancer cell; Prostate specific antigen (PSA) expression; Transcription factor

Indexed keywords

CELLS; DNA; GENES; MUTAGENESIS; TUMORS;

BIOINFORMATICS; CROSS-MODULATION; PROMOTER TRANSACTIVATION; X-FACTOR-BINDING ELEMENT (XBE);

BIOCHEMISTRY;

ANDROGEN RECEPTOR; GLUCOCORTICOID RECEPTOR; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROSTATE SPECIFIC ANTIGEN;

ARTICLE; BIOINFORMATICS; CANCER CELL; CONTROLLED STUDY; DOWN REGULATION; ENHANCER REGION; HUMAN; HUMAN CELL; MUTAGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; BINDING SITES; CELL LINE, TUMOR; DOWN-REGULATION; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MODELS, GENETIC; NF-KAPPA B; PROMOTER REGIONS (GENETICS); PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA;

EID: 2342645462     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031661     Document Type: Article

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