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An extensive network of coupling among gene expression machines
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Maniatis T., Reed R. An extensive network of coupling among gene expression machines. Nature. 416:2002;499-506
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Nature
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Maniatis, T.1
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The interplay of nuclear mRNP assembly, mRNA surveillance and export
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Stutz F., Izaurralde E. The interplay of nuclear mRNP assembly, mRNA surveillance and export. Trends Cell Biol. 13:2003;319-327
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Trends Cell Biol
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Stutz, F.1
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How introns influence and enhance eukaryotic gene expression
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Le Hir H., Nott A., Moore M.J. How introns influence and enhance eukaryotic gene expression. Trends Biochem Sci. 28:2003;215-220
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Trends Biochem Sci
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Proofreading and aminoacylation of tRNAs before export from the nucleus
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Lund E., Dahlberg J.E. Proofreading and aminoacylation of tRNAs before export from the nucleus. Science. 282:1998;2082-2085
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Integration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway
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Schell T., Kulozik A.E., Hentze M.W. Integration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway. Genome Biol. 3:2002;1006
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Genome Biol
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Schell, T.1
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Quality control of mRNA function
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Maquat L.E., Carmichael G.G. Quality control of mRNA function. Cell. 104:2001;173-176
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Maquat, L.E.1
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Coupled transcription and translation within nuclei of mammalian cells
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Iborra F.J., Jackson D.A., Cook P.R. Coupled transcription and translation within nuclei of mammalian cells. Science. 293:2001;1139-1142
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Science
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Iborra, F.J.1
Jackson, D.A.2
Cook, P.R.3
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11
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0036862513
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Induction of protein translation by ADAR1 within living cell nuclei is not dependent on RNA editing
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A study showing that over-expression of various parts of an RNA-modifying enzyme can affect the nuclear localization of a chimeric protein; the data do not address the assumption stated in the title that protein translation occurs in living cell nuclei.
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Herbert A., Wagner S., Nickerson J.A. Induction of protein translation by ADAR1 within living cell nuclei is not dependent on RNA editing. Mol Cell. 10:2002;1235-1246 A study showing that over-expression of various parts of an RNA-modifying enzyme can affect the nuclear localization of a chimeric protein; the data do not address the assumption stated in the title that protein translation occurs in living cell nuclei.
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Mol Cell
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Herbert, A.1
Wagner, S.2
Nickerson, J.A.3
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12
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0037025175
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Alternatively spliced TCR mRNA induced by disruption of reading frame
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Experiments demonstrating that NAS works in trans, because a PTC in one mRNA affects splicing of another, arguing for feedback between translation and splicing.
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Wang J., Hamilton J.I., Carter M.S., Li S., Wilkinson M. Alternatively spliced TCR mRNA induced by disruption of reading frame. Science. 297:2002;108-110 Experiments demonstrating that NAS works in trans, because a PTC in one mRNA affects splicing of another, arguing for feedback between translation and splicing.
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Science
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Wang, J.1
Hamilton, J.I.2
Carter, M.S.3
Li, S.4
Wilkinson, M.5
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14
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0037275978
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Nuclear translation: What is the evidence?
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A critical analysis of papers published up to fall, 2002, in which arguments were made in favor of and against nuclear translation.
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Dahlberg J.E., Lund E., Goodwin E.B. Nuclear translation: what is the evidence? RNA. 9:2003;1-8 A critical analysis of papers published up to fall, 2002, in which arguments were made in favor of and against nuclear translation.
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RNA
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Dahlberg, J.E.1
Lund, E.2
Goodwin, E.B.3
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15
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0037278925
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Nuclear protein synthesis: A re-evaluation
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A re-evaluation of experiments [9] that had been interpreted as demonstrating translation within isolated nuclei, showing that the earlier results could be a consequence of cytoplasmic contamination.
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Nathanson L., Xia T., Deutscher M.P. Nuclear protein synthesis: a re-evaluation. RNA. 9:2002;9-13 A re-evaluation of experiments [9] that had been interpreted as demonstrating translation within isolated nuclei, showing that the earlier results could be a consequence of cytoplasmic contamination.
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RNA
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Nathanson, L.1
Xia, T.2
Deutscher, M.P.3
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The nucleolus and the four ribonucleoproteins of translation
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Pederson T., Politz J.C. The nucleolus and the four ribonucleoproteins of translation. J Cell Biol. 148:2000;1091-1095
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Pederson, T.1
Politz, J.C.2
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0037844806
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The role of NMD3 protein in the export of 60S subunits from nuclei of Xenopus oocytes
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Trotta C.R., Lund E., Kahan L., Johnson A., Dahlberg J.E. The role of NMD3 protein in the export of 60S subunits from nuclei of Xenopus oocytes. EMBO J. 22:2003;2841-2851
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EMBO J
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Trotta, C.R.1
Lund, E.2
Kahan, L.3
Johnson, A.4
Dahlberg, J.E.5
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18
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17544384515
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The Chironomus tentans translation intitation factore eIF4H is present in the nucleus but does not bind to mRNA until the mRNA reaches the cytoplasmic perinuclear region
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A study examining whether a translation initiation factor functions when it is in the nucleus.
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Björk P., Bauren G., Gelius B., Wrange Ö., Wieslander L. The Chironomus tentans translation intitation factore eIF4H is present in the nucleus but does not bind to mRNA until the mRNA reaches the cytoplasmic perinuclear region. J Cell Sci. 116:2003;4521-4532 A study examining whether a translation initiation factor functions when it is in the nucleus.
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J Cell Sci
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Björk, P.1
Bauren, G.2
Gelius, B.3
Wrange, Ö.4
Wieslander, L.5
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19
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0037112790
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Exp5 exports eEF1a via tRNA from nuclei and synergises with other transport pathways to confine translation to the cytoplasm
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Experiments showing that several translation factors are actively exported from nuclei and hence are present in very low amounts within nuclei (see also [20]).
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Bohnsack M., Regener K., Schwappach B., Saffrich R., Paraskeva E., Hartmann E., Gorlich D. Exp5 exports eEF1a via tRNA from nuclei and synergises with other transport pathways to confine translation to the cytoplasm. EMBO J. 21:2002;6205-6215 Experiments showing that several translation factors are actively exported from nuclei and hence are present in very low amounts within nuclei (see also [20]).
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EMBO J
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Bohnsack, M.1
Regener, K.2
Schwappach, B.3
Saffrich, R.4
Paraskeva, E.5
Hartmann, E.6
Gorlich, D.7
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20
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0037112842
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Exportin 5 mediated nuclear export of elongation factor 1A and tRNA
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Calado A., Treichel N., Müller E.-C., Otto A., Kutay U. Exportin 5 mediated nuclear export of elongation factor 1A and tRNA. EMBO J. 21:2002;6216-6224
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EMBO J
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Calado, A.1
Treichel, N.2
Müller, E.-C.3
Otto, A.4
Kutay, U.5
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21
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0037099212
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NASty effects on fibrillin pre-mRNA splicing: Another case of ESE does it, but proposals for translation-dependent splice site choice live on
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Maquat L.E. NASty effects on fibrillin pre-mRNA splicing: another case of ESE does it, but proposals for translation-dependent splice site choice live on. Genes Dev. 16:2002;1743-1753
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Genes Dev
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Maquat, L.E.1
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RNA surveillance by nuclear scanning?
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Wilkinson M., Shyu A. RNA surveillance by nuclear scanning? Nat Cell Biol. 4:2002;E144-E147
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Nat Cell Biol
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Wilkinson, M.1
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Pre-mRNA processing: Insights from nonsense
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Brogna S. Pre-mRNA processing: insights from nonsense. Curr Biol. 11:2001;R838-R841
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Curr Biol
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Brogna, S.1
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24
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0346497767
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HRIP, a cellular cofactor for Rev function, promotes release of HIV RNAs from the perinuclear region
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Experiments showing that newly exported mRNAs are associated with perinuclear structures.
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Sanchez-Velar N., Udofia E.B., Yu Z., Zapp M.L. hRIP, a cellular cofactor for Rev function, promotes release of HIV RNAs from the perinuclear region. Genes Dev. 18:2004;23-34 Experiments showing that newly exported mRNAs are associated with perinuclear structures.
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Genes Dev
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Sanchez-Velar, N.1
Udofia, E.B.2
Yu, Z.3
Zapp, M.L.4
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25
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0041832111
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Partitioning and translation of mRNAs encoding soluble proteins on membrane-bound ribosomes
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Experiments showing that a wide variety of mRNAs are transiently associated with ribosomes that are bound to the endoplasmic reticulum.
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Lerner R.S., Seiser R.M., Zheng T., Lager P.J., Reedy M.C., Keene J.D., Nicchitta C.V. Partitioning and translation of mRNAs encoding soluble proteins on membrane-bound ribosomes. RNA. 9:2003;1123-1137 Experiments showing that a wide variety of mRNAs are transiently associated with ribosomes that are bound to the endoplasmic reticulum.
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RNA
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Lerner, R.S.1
Seiser, R.M.2
Zheng, T.3
Lager, P.J.4
Reedy, M.C.5
Keene, J.D.6
Nicchitta, C.V.7
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26
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0035823036
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Evidence for a pioneer round of mRNA translation: MRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20
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Ishigaki Y., Li X., Serin G., Maquat L.E. Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20. Cell. 106:2001;607-617
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Cell
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Ishigaki, Y.1
Li, X.2
Serin, G.3
Maquat, L.E.4
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27
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0036207384
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Listening to silence and understanding nonsense: Exonic mutations that affect splicing
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Cartegni L., Chew S.L., Krainer A.R. Listening to silence and understanding nonsense: exonic mutations that affect splicing. Nat Rev Genet. 3:2002;285-298
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Nat Rev Genet
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Cartegni, L.1
Chew, S.L.2
Krainer, A.R.3
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28
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0037099302
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A nonsense mutation in the fibrillin-1 gene of a Marfan syndrome patient induces NMD and disrupts an exonic splicing enhancer
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A thorough and careful demonstration of how a mutation that creates a PTC affects splicing by inactivating an ESE.
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Caputi M., Kendzior R.J., Beemon K.L. A nonsense mutation in the fibrillin-1 gene of a Marfan syndrome patient induces NMD and disrupts an exonic splicing enhancer. Genes Dev. 16:2002;1754-1759 A thorough and careful demonstration of how a mutation that creates a PTC affects splicing by inactivating an ESE.
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Genes Dev
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Caputi, M.1
Kendzior, R.J.2
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0036809882
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Nonsense-associated altered splicing: A frame-dependent response distinct from nonsense-mediated decay
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Wang J., Chang Y., Hamilton J.I., Wilkinson M.F. Nonsense-associated altered splicing: a frame-dependent response distinct from nonsense-mediated decay. Mol Cell. 10:2002;951-957
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Mol Cell
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Wang, J.1
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0034886974
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Precursor RNAs harboring nonsense codons accumulate near the site of transcription
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Mühlemann O., Mock-Casagrande C.S., Wang J., Li S., Custodio N., Carmo-Fonseca M., Wilkinson M.F., Moore M.J. Precursor RNAs harboring nonsense codons accumulate near the site of transcription. Mol Cell. 8:2001;33-43
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Mol Cell
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Carmo-Fonseca, M.6
Wilkinson, M.F.7
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Premature termination codons do not affect the rate of splicing of neighboring introns
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Iborra F.J., Escargueil A.E., Kwek K.Y., Akoulitchev A., Cook P.R. Molecular cross-talk between the transcription, translation, and nonsense-mediated decay machineries. J Cell Sci. 117:2004;899-906
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Iborra, F.J.1
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