메뉴 건너뛰기




Volumn 3, Issue 1, 1998, Pages 17-25

The anti-cancer drug etoposide can induce caspase-8 processing and apoptosis in the absence of CD95 receptor-ligand interaction

Author keywords

Anti cancer drug; Apoptosis; CD95 (APO 1 Fas); DNA damage; Etoposide

Indexed keywords


EID: 2342625486     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1009603001888     Document Type: Article
Times cited : (26)

References (40)
  • 2
    • 0028983657 scopus 로고
    • Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T cell hybridomas
    • Brunner T, Mogli RJ, LaFace D, et al. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T cell hybridomas. Nature 1995; 373: 441-444.
    • (1995) Nature , vol.373 , pp. 441-444
    • Brunner, T.1    Mogli, R.J.2    LaFace, D.3
  • 3
    • 0028893078 scopus 로고
    • Fas (CD95)/FasL interactions required for programmed cell death after T-cell activation
    • Ju S-T, Panka DJ, Cul H, et al. Fas (CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 1995; 373: 444-448.
    • (1995) Nature , vol.373 , pp. 444-448
    • Ju, S.-T.1    Panka, D.J.2    Cul, H.3
  • 4
    • 0027314703 scopus 로고
    • Mature T cells of the autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide
    • Russell JH, Rush B, Weaver C, Wang R. Mature T cells of the autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc Natl Acad Sci USA 1993; 90: 4409-4413.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4409-4413
    • Russell, J.H.1    Rush, B.2    Weaver, C.3    Wang, R.4
  • 5
    • 0028485743 scopus 로고
    • The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice
    • Singer GC, Abbas A. The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1994; 1: 365-371.
    • (1994) Immunity , vol.1 , pp. 365-371
    • Singer, G.C.1    Abbas, A.2
  • 6
    • 0029935682 scopus 로고    scopus 로고
    • Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells
    • Friesen C, Herr I, Krammer PH, Debatin K-M. Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nature Med 1996; 2: 574-577.
    • (1996) Nature Med , vol.2 , pp. 574-577
    • Friesen, C.1    Herr, I.2    Krammer, P.H.3    Debatin, K.-M.4
  • 7
    • 0040419494 scopus 로고    scopus 로고
    • Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild type p53
    • Müller M, Strand S, Hug H, et al. Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild type p53. J Clin Invest 1997; 99: 403-413.
    • (1997) J Clin Invest , vol.99 , pp. 403-413
    • Müller, M.1    Strand, S.2    Hug, H.3
  • 9
    • 0030814675 scopus 로고    scopus 로고
    • Caspases: Killer proteases
    • Nicholson D, Thornberry NA. Caspases: killer proteases. TIBS 1997; 22: 299-306.
    • (1997) TIBS , vol.22 , pp. 299-306
    • Nicholson, D.1    Thornberry, N.A.2
  • 10
    • 0029026548 scopus 로고
    • FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
    • Chinnaiyan AM, O'Rourke K, Tewari M, Dixit VM. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 1995; 81: 505-512.
    • (1995) Cell , vol.81 , pp. 505-512
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Tewari, M.3    Dixit, V.M.4
  • 11
    • 15844412409 scopus 로고    scopus 로고
    • FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
    • Muzio M, Chinnaiyan AM, Kischkel FC, et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 1996; 85: 817-827.
    • (1996) Cell , vol.85 , pp. 817-827
    • Muzio, M.1    Chinnaiyan, A.M.2    Kischkel, F.C.3
  • 12
    • 0030011398 scopus 로고    scopus 로고
    • Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
    • Boldin MP, Goncharov TM, Goltsev YV, Wallach D. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 1996; 85: 803-815.
    • (1996) Cell , vol.85 , pp. 803-815
    • Boldin, M.P.1    Goncharov, T.M.2    Goltsev, Y.V.3    Wallach, D.4
  • 13
    • 0344053451 scopus 로고    scopus 로고
    • In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
    • Fernandes-Alnemri T, Armstrong RC, Krebs J, et al. In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Proc Natl Acad Sci USA 1996; 93: 7464-7469.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7464-7469
    • Fernandes-Alnemri, T.1    Armstrong, R.C.2    Krebs, J.3
  • 15
    • 0029670910 scopus 로고    scopus 로고
    • CPP-32/Apopain is the key interleukin-1β-converting enzyme-like protease involved in Fas-mediated apoptosis
    • Schlegel J, Peters I, Orrenius S, et al. CPP-32/Apopain is the key interleukin-1β-converting enzyme-like protease involved in Fas-mediated apoptosis. J Biol Chem 1996; 271: 1841-1844.
    • (1996) J Biol Chem , vol.271 , pp. 1841-1844
    • Schlegel, J.1    Peters, I.2    Orrenius, S.3
  • 16
    • 0029905073 scopus 로고    scopus 로고
    • Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases
    • Srinivasula SM, Ahmad M, Fernandes-Alnemri T, Litwack G, Alnemri ES. Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases. Proc Natl Acad Sci USA 1996; 93: 14486-14491.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14486-14491
    • Srinivasula, S.M.1    Ahmad, M.2    Fernandes-Alnemri, T.3    Litwack, G.4    Alnemri, E.S.5
  • 17
    • 0021333644 scopus 로고
    • Mechanism of antitumor drug action: Poisoning of mammalian DNA topoisomerase II on DNA by 4′-(9-acridinylamino)-methanesulfon-m-anisidide
    • Nelson EM, Tewey KM, Liu LF. Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4′-(9-acridinylamino)-methanesulfon-m-anisidide. Proc Natl Acad Sci USA 1984; 81: 1361-1365.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 1361-1365
    • Nelson, E.M.1    Tewey, K.M.2    Liu, L.F.3
  • 18
    • 0021767901 scopus 로고
    • Phaseolus vulgaris phytohaemagglutinin (PHA) binds to the human T lymphocyte antigen receptor
    • Chilson OP, Boylston AW, Crumpton MJ. Phaseolus vulgaris phytohaemagglutinin (PHA) binds to the human T lymphocyte antigen receptor. EMBO J 1984; 3: 3239-3245.
    • (1984) EMBO J , vol.3 , pp. 3239-3245
    • Chilson, O.P.1    Boylston, A.W.2    Crumpton, M.J.3
  • 19
    • 0027291205 scopus 로고
    • Lethal effects of the anti-Fas antibody in mice
    • Ogasawara J, Watenabe-Fukunaga R, Adachi M, et al. Lethal effects of the anti-Fas antibody in mice. Nature 1993; 364: 806-809.
    • (1993) Nature , vol.364 , pp. 806-809
    • Ogasawara, J.1    Watenabe-Fukunaga, R.2    Adachi, M.3
  • 20
    • 0026568919 scopus 로고
    • Lympho- proliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • Watanabe-Fukunaga R, Brannan C, Copeland NG, Jenkins NA, Nagata S. Lympho- proliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992; 356: 314-317.
    • (1992) Nature , vol.356 , pp. 314-317
    • Watanabe-Fukunaga, R.1    Brannan, C.2    Copeland, N.G.3    Jenkins, N.A.4    Nagata, S.5
  • 22
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Meth 1991; 139: 271-279.
    • (1991) J Immunol Meth , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 23
    • 0023851906 scopus 로고
    • Molecular analysis of mutations induced by N-ethyl-N-nitrosourea at HPRT locus in mouse lymphoma cells
    • Vrieling H, Niericker MJ, Simons JWIM, van Zeeland AA. Molecular analysis of mutations induced by N-ethyl-N-nitrosourea at HPRT locus in mouse lymphoma cells. Mut Res 1988; 198: 99-106.
    • (1988) Mut Res , vol.198 , pp. 99-106
    • Vrieling, H.1    Niericker, M.J.2    Simons, J.W.I.M.3    Van Zeeland, A.A.4
  • 24
    • 0026521388 scopus 로고
    • Identification and cloning of two overexpressed genes U21B31/PRAD1 and EMS1, within the amplified chromosome 11q13 region in human carcinomas
    • Schuuring E, Verhoeven E, Mooi WJ, Michalides RJAM. Identification and cloning of two overexpressed genes U21B31/PRAD1 and EMS1, within the amplified chromosome 11q13 region in human carcinomas. Oncogene 1992; 7: 355-361.
    • (1992) Oncogene , vol.7 , pp. 355-361
    • Schuuring, E.1    Verhoeven, E.2    Mooi, W.J.3    Michalides, R.J.A.M.4
  • 25
    • 0030925774 scopus 로고    scopus 로고
    • FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
    • Medema J-P, Scaffidi C, Kischkel F, et al. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J 1997; 16: 2794-2804.
    • (1997) EMBO J , vol.16 , pp. 2794-2804
    • Medema, J.-P.1    Scaffidi, C.2    Kischkel, F.3
  • 26
    • 0029853389 scopus 로고    scopus 로고
    • Pivotal role of a DEVD-sensitive step in etoposide-induced and Fas-mediated apoptotic pathways
    • Dubrez L, Savoy I, Hamman A, Solary E. Pivotal role of a DEVD-sensitive step in etoposide-induced and Fas-mediated apoptotic pathways. EMBO J 1996; 15: 5504-5512.
    • (1996) EMBO J , vol.15 , pp. 5504-5512
    • Dubrez, L.1    Savoy, I.2    Hamman, A.3    Solary, E.4
  • 27
    • 0029894283 scopus 로고    scopus 로고
    • Activation of the CPP32 apoptotic protease by distinct signaling pathways with differential sensitivity to Bcl-XL
    • Erhardt P, Cooper G. Activation of the CPP32 apoptotic protease by distinct signaling pathways with differential sensitivity to Bcl-XL. J Biol Chem 1996; 271: 17601-17604.
    • (1996) J Biol Chem , vol.271 , pp. 17601-17604
    • Erhardt, P.1    Cooper, G.2
  • 28
    • 15444344933 scopus 로고    scopus 로고
    • Activation of multiple interleukin-1β converting enzyme homologues in cytosol and nuclei of HL-60 cells during etoposide-induced apoptosis
    • Martins LM, Kottke T, Mesner PW, et al. Activation of multiple interleukin-1β converting enzyme homologues in cytosol and nuclei of HL-60 cells during etoposide-induced apoptosis. J Biol Chem 1997; 272: 7421-7430.
    • (1997) J Biol Chem , vol.272 , pp. 7421-7430
    • Martins, L.M.1    Kottke, T.2    Mesner, P.W.3
  • 29
    • 0030996297 scopus 로고    scopus 로고
    • The receptor for the cytotoxic ligand TRAIL
    • Pan G, O'Rourke K, Chinnaiyan AM, et al. The receptor for the cytotoxic ligand TRAIL. Science 1997; 276: 111-113.
    • (1997) Science , vol.276 , pp. 111-113
    • Pan, G.1    O'Rourke, K.2    Chinnaiyan, A.M.3
  • 30
    • 10544236916 scopus 로고    scopus 로고
    • Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95
    • Chinnayian AM, O'Rourke K, Yu G-L, et al. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science 1996; 274: 990-992.
    • (1996) Science , vol.274 , pp. 990-992
    • Chinnayian, A.M.1    O'Rourke, K.2    Yu, G.-L.3
  • 31
    • 0029969717 scopus 로고    scopus 로고
    • A death-domain-containing receptor that mediates apoptosis
    • Kitson J, Raven T, Jiang Y-P, et al. A death-domain-containing receptor that mediates apoptosis. Nature 1996; 384: 372-375.
    • (1996) Nature , vol.384 , pp. 372-375
    • Kitson, J.1    Raven, T.2    Jiang, Y.-P.3
  • 32
    • 0030466894 scopus 로고    scopus 로고
    • Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-kB
    • Marsters SA, Sheridan JP, Donahue CJ, et al. Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-kB. Curr Biol 1996; 6: 1669-1676.
    • (1996) Curr Biol , vol.6 , pp. 1669-1676
    • Marsters, S.A.1    Sheridan, J.P.2    Donahue, C.J.3
  • 33
    • 0030896087 scopus 로고    scopus 로고
    • TRAMP, a novel apoptosis-mediating receptor with sequence homology to Tumor Necrosis Factor Receptor 1 and Fas(Apo-1/CD95)
    • Bodmer J-L, Burns K, Schneider P, et al. TRAMP, a novel apoptosis-mediating receptor with sequence homology to Tumor Necrosis Factor Receptor 1 and Fas(Apo-1/CD95). Immunity 1997; 6: 79-88.
    • (1997) Immunity , vol.6 , pp. 79-88
    • Bodmer, J.-L.1    Burns, K.2    Schneider, P.3
  • 34
    • 0024237306 scopus 로고
    • Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum
    • Fujiwara T, Oda K, Takasuki A, Ikehara Y. Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum. J Biol Chem 1988; 263: 18545-18552.
    • (1988) J Biol Chem , vol.263 , pp. 18545-18552
    • Fujiwara, T.1    Oda, K.2    Takasuki, A.3    Ikehara, Y.4
  • 35
    • 0028990125 scopus 로고
    • Yama/CPP32b a mammalian homologue of CED-3 is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
    • Tewari M, Quan LT, O'Rourke K, et al. Yama/CPP32b a mammalian homologue of CED-3 is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 1995; 81: 801-809.
    • (1995) Cell , vol.81 , pp. 801-809
    • Tewari, M.1    Quan, L.T.2    O'Rourke, K.3
  • 37
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • 1995
    • Miyashita T, Reed JC. 1995. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995; 80: 293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 38
    • 0029669929 scopus 로고    scopus 로고
    • T cells from baxa transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced death in the absence of p53
    • Brady HJM, Salamons GS, Bobeldijk RC, Berns AJM. T cells from baxa transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced death in the absence of p53. EMBO J 1996; 15: 1221-1230.
    • (1996) EMBO J , vol.15 , pp. 1221-1230
    • Brady, H.J.M.1    Salamons, G.S.2    Bobeldijk, R.C.3    Berns, A.J.M.4
  • 39
    • 0029003501 scopus 로고
    • Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression
    • Owen-Schaub LB, Zhang W, Cusak JC, et al. Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol Cell Biol 1995; 15: 3032-3040.
    • (1995) Mol Cell Biol , vol.15 , pp. 3032-3040
    • Owen-Schaub, L.B.1    Zhang, W.2    Cusak, J.C.3
  • 40
    • 0029609086 scopus 로고
    • Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
    • Strasser A, Harris AW, Huang DCS, Krammer PH, Cory S. Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J 1995; 14: 6136-6147.
    • (1995) EMBO J , vol.14 , pp. 6136-6147
    • Strasser, A.1    Harris, A.W.2    Huang, D.C.S.3    Krammer, P.H.4    Cory, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.