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Volumn 84, Issue 4, 2004, Pages 406-417

Neuroblastoma cells with overexpressed MYCN retain their capacity to undergo neuronal differentiation

Author keywords

Carcinogenesis; Development; Differentiation; MYCN; Neuroblastoma; Sympathetic nervous system

Indexed keywords

ARTICLE; CELL CULTURE; CONTROLLED STUDY; GENE AMPLIFICATION; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; NERVE CELL DIFFERENTIATION; NEUROBLAST; NEUROBLASTOMA; NORTHERN BLOTTING; ONCOGENE C MYB; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING; ADRENERGIC SYSTEM; CELL DIFFERENTIATION; DRUG EFFECT; GENETICS; METABOLISM; NERVE CELL; ONCOGENE MYC; PATHOLOGY; PHYSIOLOGY;

EID: 2342614314     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.3700061     Document Type: Article
Times cited : (41)

References (65)
  • 1
    • 0021063273 scopus 로고
    • Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour
    • Schwab M, Schwab M, Alitalo K, et al. Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature 1983;305:245-248.
    • (1983) Nature , vol.305 , pp. 245-248
    • Schwab, M.1    Alitalo, K.2
  • 2
    • 0021047844 scopus 로고
    • Transposition and amplification of oncogene-related sequences in human neuroblastomas
    • Kohl NE, Kanda N, Schreck RR, et al. Transposition and amplification of oncogene-related sequences in human neuroblastomas. Cell 1983;35:359-367.
    • (1983) Cell , vol.35 , pp. 359-367
    • Kohl, N.E.1    Kanda, N.2    Schreck, R.R.3
  • 3
    • 0021705664 scopus 로고
    • Activated expression of the N-myc gene in human neuroblastomas and related tumors
    • Kohl NE, Gee CE, Alt FW. Activated expression of the N-myc gene in human neuroblastomas and related tumors. Science 1984;226:1335-1337.
    • (1984) Science , vol.226 , pp. 1335-1337
    • Kohl, N.E.1    Gee, C.E.2    Alt, F.W.3
  • 4
    • 0013288537 scopus 로고
    • Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma
    • Schwab M, Ellison J, Busch M, et al. Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma. Proc Natl Acad Sci USA 1984;81:4940-4944.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 4940-4944
    • Schwab, M.1    Ellison, J.2    Busch, M.3
  • 5
    • 0021261878 scopus 로고
    • Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
    • Brodeur GM, Seeger RC, Schwab M, et al. Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science 1984;224:1121-1124.
    • (1984) Science , vol.224 , pp. 1121-1124
    • Brodeur, G.M.1    Seeger, R.C.2    Schwab, M.3
  • 6
    • 0000222605 scopus 로고    scopus 로고
    • Genetic and biological markers of prognosis in neuroblastoma
    • Brodeur GM, Sawada T, Tsuchida Y, Voütes PA (eds). Elsevier Science B.V.: Amsterdam, The Netherlands
    • Brodeur GM, Ambros PF. Genetic and biological markers of prognosis in neuroblastoma. In: Brodeur GM, Sawada T, Tsuchida Y, Voütes PA (eds) Neuroblastoma. Elsevier Science B.V.: Amsterdam, The Netherlands, 2000, pp. 355-369.
    • (2000) Neuroblastoma , pp. 355-369
    • Brodeur, G.M.1    Ambros, P.F.2
  • 7
    • 0022388606 scopus 로고
    • Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas
    • Seeger RC, Brodeur GM, Sather H, et al. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med 1985;313:1111-1116.
    • (1985) N Engl J Med , vol.313 , pp. 1111-1116
    • Seeger, R.C.1    Brodeur, G.M.2    Sather, H.3
  • 8
    • 0030999641 scopus 로고    scopus 로고
    • Targeted expression of MYCN causes neuroblastoma in transgenic mice
    • Weiss WA, Aldape K, Mohapatra G, et al. Targeted expression of MYCN causes neuroblastoma in transgenic mice. EMBO J 1997;16:2985-2995.
    • (1997) EMBO J , vol.16 , pp. 2985-2995
    • Weiss, W.A.1    Aldape, K.2    Mohapatra, G.3
  • 9
    • 0036469268 scopus 로고    scopus 로고
    • N-myc promotes survival and induces S-phase entry of postmitotic sympathetic neurons
    • Wartiovaara K, Barnabe-Heider F, Miller FD, et al. N-myc promotes survival and induces S-phase entry of postmitotic sympathetic neurons. J Neurosci 2002;22:815-824.
    • (2002) J Neurosci , vol.22 , pp. 815-824
    • Wartiovaara, K.1    Barnabe-Heider, F.2    Miller, F.D.3
  • 10
    • 0029743372 scopus 로고    scopus 로고
    • Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells
    • Lutz W, Stohr M, Schurmann J, et al. Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells. Oncogene 1996;13:803-812.
    • (1996) Oncogene , vol.13 , pp. 803-812
    • Lutz, W.1    Stohr, M.2    Schurmann, J.3
  • 11
    • 17744400301 scopus 로고    scopus 로고
    • N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis
    • Boon K, Caron HN, van Asperen R, et al. N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis. EMBO J 2001;20:1383-1393.
    • (2001) EMBO J , vol.20 , pp. 1383-1393
    • Boon, K.1    Caron, H.N.2    Van Asperen, R.3
  • 12
    • 0025360898 scopus 로고
    • Organization and expression of the chicken N-myc gene
    • Sawai S, Kato K, Wakamatsu Y, et al. Organization and expression of the chicken N-myc gene. Mol Cell Biol 1990;10:2017-2026.
    • (1990) Mol Cell Biol , vol.10 , pp. 2017-2026
    • Sawai, S.1    Kato, K.2    Wakamatsu, Y.3
  • 13
    • 0026101357 scopus 로고
    • Tissue distribution of N-myc expression in the early organogenesis period of the mouse embryo
    • Kato K, Kanamori A, Wakamatsu Y, et al. Tissue distribution of N-myc expression in the early organogenesis period of the mouse embryo. Dev Growth Differ 1991;33:29-36.
    • (1991) Dev Growth Differ , vol.33 , pp. 29-36
    • Kato, K.1    Kanamori, A.2    Wakamatsu, Y.3
  • 14
    • 0022347548 scopus 로고
    • Expression of N-myc in teratocarcinoma stem cells and mouse embryos
    • Jakobovits A, Schwab M, Bishop JM, et al. Expression of N-myc in teratocarcinoma stem cells and mouse embryos. Nature 1985;318:188-191.
    • (1985) Nature , vol.318 , pp. 188-191
    • Jakobovits, A.1    Schwab, M.2    Bishop, J.M.3
  • 15
    • 0024095742 scopus 로고
    • N-myc proto-oncogene expression during organogenesis in the developing mouse as revealed by in situ hybridization
    • Mugrauer G, Alt FW, Ekblom P. N-myc proto-oncogene expression during organogenesis in the developing mouse as revealed by in situ hybridization. J Cell Biol 1988;107:1325-1335.
    • (1988) J Cell Biol , vol.107 , pp. 1325-1335
    • Mugrauer, G.1    Alt, F.W.2    Ekblom, P.3
  • 16
    • 0030925596 scopus 로고    scopus 로고
    • Regulation of the neural crest cell fate by N-myc: Promotion of ventral migration and neuronal differentiation
    • Wakamatsu Y, Watanabe Y, Nakamura H, et al. Regulation of the neural crest cell fate by N-myc: promotion of ventral migration and neuronal differentiation. Development 1997;124:1953-1962.
    • (1997) Development , vol.124 , pp. 1953-1962
    • Wakamatsu, Y.1    Watanabe, Y.2    Nakamura, H.3
  • 17
    • 0027312135 scopus 로고
    • Defects of embryonic organogenesis resulting from targeted disruption of the N-myc gene in the mouse
    • Sawai S, Shimono A, Wakamatsu Y, et al. Defects of embryonic organogenesis resulting from targeted disruption of the N-myc gene in the mouse. Development 1993;117:1445-1455.
    • (1993) Development , vol.117 , pp. 1445-1455
    • Sawai, S.1    Shimono, A.2    Wakamatsu, Y.3
  • 18
    • 0024203866 scopus 로고
    • Regulation of N-myc expression is a critical event controlling the ability of human neuroblasts to differentiate
    • Thiele CJ, Israel MA. Regulation of N-myc expression is a critical event controlling the ability of human neuroblasts to differentiate. Exp Cell Biol 1988;56:321-333.
    • (1988) Exp Cell Biol , vol.56 , pp. 321-333
    • Thiele, C.J.1    Israel, M.A.2
  • 19
    • 0030061540 scopus 로고    scopus 로고
    • Retinoic acid-induced growth arrest and differentiation of neuroblastoma cells are counteracted by N-myc and enhanced by max overexpressions
    • Peverali FA, Orioli D, Tonon L, et al. Retinoic acid-induced growth arrest and differentiation of neuroblastoma cells are counteracted by N-myc and enhanced by max overexpressions. Oncogene 1996;12:457-462.
    • (1996) Oncogene , vol.12 , pp. 457-462
    • Peverali, F.A.1    Orioli, D.2    Tonon, L.3
  • 20
    • 0029061588 scopus 로고
    • Biochemical evidence for a mature phenotype in morphologically poorly differentiated neuroblastomas with a favourable outcome
    • Hedborg F, Bjelfman C, Sparen P, et al. Biochemical evidence for a mature phenotype in morphologically poorly differentiated neuroblastomas with a favourable outcome. Eur J Cancer 1995;4:435-443.
    • (1995) Eur J Cancer , vol.4 , pp. 435-443
    • Hedborg, F.1    Bjelfman, C.2    Sparen, P.3
  • 21
    • 0024270389 scopus 로고
    • N-myc oncogene RNA expression in neuroblastoma
    • Nisen PD, Waber PG, Rich MA, et al. N-myc oncogene RNA expression in neuroblastoma. J Natl Cancer Inst 1988;80:1633-1637.
    • (1988) J Natl Cancer Inst , vol.80 , pp. 1633-1637
    • Nisen, P.D.1    Waber, P.G.2    Rich, M.A.3
  • 22
    • 0023762034 scopus 로고
    • Expression of N-myc by neuroblastomas with one or multiple copies of the oncogene
    • Seeger RC, Wada R, Brodeur GM, et al. Expression of N-myc by neuroblastomas with one or multiple copies of the oncogene. Prog Clin Biol Res 1988;271:41-49.
    • (1988) Prog Clin Biol Res , vol.271 , pp. 41-49
    • Seeger, R.C.1    Wada, R.2    Brodeur, G.M.3
  • 23
    • 0025269237 scopus 로고
    • Myc gene amplification and expression in primary human neuroblastoma
    • Slavc I, Ellenbogen R, Jung WH, et al. myc gene amplification and expression in primary human neuroblastoma. Cancer Res 1990;50:1459-1463.
    • (1990) Cancer Res , vol.50 , pp. 1459-1463
    • Slavc, I.1    Ellenbogen, R.2    Jung, W.H.3
  • 24
    • 0030861490 scopus 로고    scopus 로고
    • MYCN protein expression as a predictor of neuroblastoma prognosis
    • Chan HS, Gallie BL, DeBoer G, et al. MYCN protein expression as a predictor of neuroblastoma prognosis. Clin Cancer Res 1997;3:1699-1706.
    • (1997) Clin Cancer Res , vol.3 , pp. 1699-1706
    • Chan, H.S.1    Gallie, B.L.2    DeBoer, G.3
  • 25
    • 0031727309 scopus 로고    scopus 로고
    • Prognostic significance of MYCN oncogene expression in childhood neuroblastoma
    • Bordow SB, Norris MD, Haber PS, et al. Prognostic significance of MYCN oncogene expression in childhood neuroblastoma. J Clin Oncol 1998;16:3286-3294.
    • (1998) J Clin Oncol , vol.16 , pp. 3286-3294
    • Bordow, S.B.1    Norris, M.D.2    Haber, P.S.3
  • 26
    • 0012027715 scopus 로고    scopus 로고
    • Expression of MYCN mRNA and protein
    • Brodeur GM, Sawada T, Tsuchida Y, Voütes PA (eds). Elsevier Science B.V.: Amsterdam, The Netherlands
    • Cohn SL, Ikegaki N. Expression of MYCN mRNA and protein. In: Brodeur GM, Sawada T, Tsuchida Y, Voütes PA (eds). Neuroblastoma. Elsevier Science B.V.: Amsterdam, The Netherlands, 2000, pp. 137-146.
    • (2000) Neuroblastoma , pp. 137-146
    • Cohn, S.L.1    Ikegaki, N.2
  • 27
    • 0029558742 scopus 로고
    • Over-expression of transfected N-myc oncogene in human SKNSH neuroblastoma cells down-regulates expression of beta 1 integrin subunit
    • Judware R, Culp LA. Over-expression of transfected N-myc oncogene in human SKNSH neuroblastoma cells down-regulates expression of beta 1 integrin subunit. Oncogene 1995;11:2599-2607.
    • (1995) Oncogene , vol.11 , pp. 2599-2607
    • Judware, R.1    Culp, L.A.2
  • 28
    • 0034649163 scopus 로고    scopus 로고
    • Arsenic trioxide inhibits neuroblastoma growth in vivo and promotes apoptotic cell death in vitro
    • Øra I, Bondesson L, Jonsson C, et al. Arsenic trioxide inhibits neuroblastoma growth in vivo and promotes apoptotic cell death in vitro. Biochem Biophys Res Commun 2000;277:179-185.
    • (2000) Biochem Biophys Res Commun , vol.277 , pp. 179-185
    • Øra, I.1    Bondesson, L.2    Jonsson, C.3
  • 29
    • 0024437934 scopus 로고
    • Insulin-like growth factor 2 and short-range stimulatory loops in control of human placental growth
    • Ohlsson R, Holmgren L, Glaser A, et al. Insulin-like growth factor 2 and short-range stimulatory loops in control of human placental growth. EMBO J 1989;8:1993-1999.
    • (1989) EMBO J , vol.8 , pp. 1993-1999
    • Ohlsson, R.1    Holmgren, L.2    Glaser, A.3
  • 30
    • 0027378405 scopus 로고
    • Differential expression of neurotrophin receptors during renal development
    • Durbeej M, Söderström S, Ebendal T, et al. Differential expression of neurotrophin receptors during renal development. Development 1993;119:977-989.
    • (1993) Development , vol.119 , pp. 977-989
    • Durbeej, M.1    Söderström, S.2    Ebendal, T.3
  • 31
    • 0027364823 scopus 로고
    • Human GAP-43 expression: Multiple start sites for initiation of transcription in differentiating human neuroblastoma cells
    • Örtoft E, Påhlman S, Andersson G, et al. Human GAP-43 expression: multiple start sites for initiation of transcription in differentiating human neuroblastoma cells. Mol Cell Neurosci 1993;4:549-561.
    • (1993) Mol Cell Neurosci , vol.4 , pp. 549-561
    • Örtoft, E.1    Påhlman, S.2    Andersson, G.3
  • 32
    • 0022423245 scopus 로고
    • Isolation and characterization of rat and human glyceraldehyde-3- phosphate dehydrogenase cDNAs: Genomic complexity and molecular evolution of the gene
    • Tso JY, Sun XH, Kao TH, et al. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene. Nucleic Acids Res 1985;13:2485-2502.
    • (1985) Nucleic Acids Res , vol.13 , pp. 2485-2502
    • Tso, J.Y.1    Sun, X.H.2    Kao, T.H.3
  • 33
    • 0033810134 scopus 로고    scopus 로고
    • Induced neuroblastoma cell differentiation, associated with transient HES-1 activity and reduced HASH-1 expression, is inhibited by Notch1
    • Grynfeld A, Påhlman S, Axelson H. Induced neuroblastoma cell differentiation, associated with transient HES-1 activity and reduced HASH-1 expression, is inhibited by Notch1. Int J Cancer 2000;88:401-410.
    • (2000) Int J Cancer , vol.88 , pp. 401-410
    • Grynfeld, A.1    Påhlman, S.2    Axelson, H.3
  • 34
    • 0022972956 scopus 로고
    • Characterization, sequence, and expression of the cloned human neuropeptide Y gene
    • Minth CD, Andrews PC, Dixon JE. Characterization, sequence, and expression of the cloned human neuropeptide Y gene. J Biol Chem 1986;261:11974-11979.
    • (1986) J Biol Chem , vol.261 , pp. 11974-11979
    • Minth, C.D.1    Andrews, P.C.2    Dixon, J.E.3
  • 35
    • 0036534582 scopus 로고    scopus 로고
    • Elimination of primer-dimer artifacts and genomic coamplification using a two-step SYBR green I real-time RT-PCR
    • Vandesompele J, De Paepe A, Speleman F. Elimination of primer-dimer artifacts and genomic coamplification using a two-step SYBR green I real-time RT-PCR. Anal Biochem 2002;303:95-98.
    • (2002) Anal Biochem , vol.303 , pp. 95-98
    • Vandesompele, J.1    De Paepe, A.2    Speleman, F.3
  • 36
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • Vandesompele J, De Preter K, Pattyn F, et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002;3, RESEARCH0034.
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3
  • 37
    • 0037248812 scopus 로고    scopus 로고
    • RTPrimerDB: The real-time PCR primer and probe database
    • Pattyn F, Speleman F, De Paepe A, et al. RTPrimerDB: the real-time PCR primer and probe database. Nucleic Acids Res 2003;31:122-123.
    • (2003) Nucleic Acids Res , vol.31 , pp. 122-123
    • Pattyn, F.1    Speleman, F.2    De Paepe, A.3
  • 38
    • 0029852033 scopus 로고    scopus 로고
    • A developmental model of neuroblastoma: Differentiating stroma-poor tumors' progress along an extra-adrenal chromaffin lineage
    • Hoehner JC, Gestblom C, Hedborg F, et al. A developmental model of neuroblastoma: differentiating stroma-poor tumors' progress along an extra-adrenal chromaffin lineage. Lab Invest 1996;75:659-675.
    • (1996) Lab Invest , vol.75 , pp. 659-675
    • Hoehner, J.C.1    Gestblom, C.2    Hedborg, F.3
  • 39
    • 0031022022 scopus 로고    scopus 로고
    • In vivo spontaneous neuronal to neuroendocrine lineage conversion in a subset of neuroblastomas
    • Gestblom C, Hoehner JC, Hedborg F, et al. In vivo spontaneous neuronal to neuroendocrine lineage conversion in a subset of neuroblastomas. Am J Pathol 1997;150:107-117.
    • (1997) Am J Pathol , vol.150 , pp. 107-117
    • Gestblom, C.1    Hoehner, J.C.2    Hedborg, F.3
  • 40
    • 0032946871 scopus 로고    scopus 로고
    • The basic helix-loop-helix transcription factor dHAND, a marker gene for the developing human sympathetic nervous system, is expressed in both high- and low-stage neuroblastomas
    • Gestblom C, Hoehner JC, Hedborg F, et al. The basic helix-loop-helix transcription factor dHAND, a marker gene for the developing human sympathetic nervous system, is expressed in both high- and low-stage neuroblastomas. Lab Invest 1999;79:67-79.
    • (1999) Lab Invest , vol.79 , pp. 67-79
    • Gestblom, C.1    Hoehner, J.C.2    Hedborg, F.3
  • 41
    • 0025107309 scopus 로고
    • Expression of the neuronal form of pp60c-src in neuroblastoma in relation to clinical stage and prognosis
    • Bjelfman C, Hedborg F, Johansson I, et al. Expression of the neuronal form of pp60c-src in neuroblastoma in relation to clinical stage and prognosis. Cancer Res 1990;50:6908-6914.
    • (1990) Cancer Res , vol.50 , pp. 6908-6914
    • Bjelfman, C.1    Hedborg, F.2    Johansson, I.3
  • 42
    • 0034327928 scopus 로고    scopus 로고
    • MYCN expression is not prognostic of adverse outcome in advanced-stage neuroblastoma with nonamplified MYCN
    • Cohn SL, London WB, Huang D, et al. MYCN expression is not prognostic of adverse outcome in advanced-stage neuroblastoma with nonamplified MYCN. J Clin Oncol 2000;18:3604-3613.
    • (2000) J Clin Oncol , vol.18 , pp. 3604-3613
    • Cohn, S.L.1    London, W.B.2    Huang, D.3
  • 43
    • 0024468519 scopus 로고
    • Suppression of MYC by high expression of NMYC in human neuroblastoma cells
    • Breit S, Schwab M. Suppression of MYC by high expression of NMYC in human neuroblastoma cells. J Neurosci Res 1989;24:21-28.
    • (1989) J Neurosci Res , vol.24 , pp. 21-28
    • Breit, S.1    Schwab, M.2
  • 44
    • 0037461898 scopus 로고    scopus 로고
    • ID2 expression in neuroblastoma does not correlate to MYCN levels and lacks prognostic value
    • Vandesompele J, Edsjö A, De Preter K, et al. ID2 expression in neuroblastoma does not correlate to MYCN levels and lacks prognostic value. Oncogene 2003;22:456-460.
    • (2003) Oncogene , vol.22 , pp. 456-460
    • Vandesompele, J.1    Edsjö, A.2    De Preter, K.3
  • 45
    • 0015817744 scopus 로고
    • Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture
    • Biedler JL, Helson L, Spengler BA. Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture. Cancer Res 1973;33:2643-2652.
    • (1973) Cancer Res , vol.33 , pp. 2643-2652
    • Biedler, J.L.1    Helson, L.2    Spengler, B.A.3
  • 46
    • 0034662610 scopus 로고    scopus 로고
    • The N-myc oncogene in human neuroblastoma cells: Down-regulation of an angiogenesis inhibitor identified as activin a
    • Breit S, Ashman K, Wilting J, et al. The N-myc oncogene in human neuroblastoma cells: down-regulation of an angiogenesis inhibitor identified as activin A. Cancer Res 2000;60:4596-4601.
    • (2000) Cancer Res , vol.60 , pp. 4596-4601
    • Breit, S.1    Ashman, K.2    Wilting, J.3
  • 47
    • 0030938857 scopus 로고    scopus 로고
    • Concomitant down-regulation of expression of integrin subunits by N-myc in human neuroblastoma cells: Differential regulation of alpha2, alpha3 and beta1
    • Judware R, Culp LA. Concomitant down-regulation of expression of integrin subunits by N-myc in human neuroblastoma cells: differential regulation of alpha2, alpha3 and beta1. Oncogene 1997;14:1341-1350.
    • (1997) Oncogene , vol.14 , pp. 1341-1350
    • Judware, R.1    Culp, L.A.2
  • 48
    • 0031025014 scopus 로고    scopus 로고
    • Persistent alpha1 integrin subunit expression in human neuroblastoma cell lines which overexpress N-myc and downregulate other integrin subunits
    • Judware R, Culp LA. Persistent alpha1 integrin subunit expression in human neuroblastoma cell lines which overexpress N-myc and downregulate other integrin subunits. Oncol Rep 1997;4:433-437.
    • (1997) Oncol Rep , vol.4 , pp. 433-437
    • Judware, R.1    Culp, L.A.2
  • 49
    • 0021029723 scopus 로고
    • Coordinate morphological and biochemical interconversion of human neuroblastoma cells
    • Ross RA, Spengler BA, Biedler JL. Coordinate morphological and biochemical interconversion of human neuroblastoma cells. J Natl Cancer Inst 1983;71:741-747.
    • (1983) J Natl Cancer Inst , vol.71 , pp. 741-747
    • Ross, R.A.1    Spengler, B.A.2    Biedler, J.L.3
  • 50
    • 0019468847 scopus 로고
    • Phenotypic changes of human neuroblastoma cells in culture induced by 12-O-tetradecanoyl-phorbol-13-acetate
    • Påhlman S, Odelstad L, Larsson E, et al. Phenotypic changes of human neuroblastoma cells in culture induced by 12-O-tetradecanoyl-phorbol-13- acetate. Int J Cancer 1981;28:583-589.
    • (1981) Int J Cancer , vol.28 , pp. 583-589
    • Påhlman, S.1    Odelstad, L.2    Larsson, E.3
  • 51
    • 0021176611 scopus 로고
    • Retinoic acid-induced differentiation of cultured human neuroblastoma cells: A comparison with phorbolester-induced differentiation
    • Påhlman S, Ruusala AI, Abrahamsson L, et al. Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbolester-induced differentiation. Cell Differ 1984;14:135-144.
    • (1984) Cell Differ , vol.14 , pp. 135-144
    • Påhlman, S.1    Ruusala, A.I.2    Abrahamsson, L.3
  • 52
    • 0023223166 scopus 로고
    • Muscarinic receptors in human SH-SY5Y neuroblastoma cell line: Regulation by phorbol ester and retinoic acid-induced differentiation
    • Adem A, Mattsson ME, Nordberg A, et al. Muscarinic receptors in human SH-SY5Y neuroblastoma cell line: regulation by phorbol ester and retinoic acid-induced differentiation. Brain Res 1987;430:235-242.
    • (1987) Brain Res , vol.430 , pp. 235-242
    • Adem, A.1    Mattsson, M.E.2    Nordberg, A.3
  • 53
    • 0038340662 scopus 로고    scopus 로고
    • Expression of trkB in human neuroblastoma in relation to MYCN expression and retinoic acid treatment
    • Edsjö AA, Lavenius E, Nilsson H, et al. Expression of trkB in human neuroblastoma in relation to MYCN expression and retinoic acid treatment. Lab Invest 2003;83:813-823.
    • (2003) Lab Invest , vol.83 , pp. 813-823
    • Edsjö, A.A.1    Lavenius, E.2    Nilsson, H.3
  • 54
    • 0025012642 scopus 로고
    • Early activation of endogenous pp60src kinase activity during neuronal differentiation of cultured human neuroblastoma cells
    • Bjelfman C, Meyerson G, Cartwright CA, et al. Early activation of endogenous pp60src kinase activity during neuronal differentiation of cultured human neuroblastoma cells. Mol Cell Biol 1990;10:361-370.
    • (1990) Mol Cell Biol , vol.10 , pp. 361-370
    • Bjelfman, C.1    Meyerson, G.2    Cartwright, C.A.3
  • 55
    • 0027323932 scopus 로고
    • Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells
    • Eukaryotic Signal Transduction Group
    • Kaplan DR, Matsumoto K, Lucarelli E, et al. Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells. Eukaryotic Signal Transduction Group. Neuron 1993;11:321-331.
    • (1993) Neuron , vol.11 , pp. 321-331
    • Kaplan, D.R.1    Matsumoto, K.2    Lucarelli, E.3
  • 56
    • 0028038917 scopus 로고
    • Basic FGF and IGF-I promote differentiation of human SH-SY5Y neuroblastoma cells in culture
    • Lavenius E, Parrow V, Nånberg E, et al. Basic FGF and IGF-I promote differentiation of human SH-SY5Y neuroblastoma cells in culture. Growth Factors 1994;10:29-39.
    • (1994) Growth Factors , vol.10 , pp. 29-39
    • Lavenius, E.1    Parrow, V.2    Nånberg, E.3
  • 57
    • 0023099920 scopus 로고
    • Phenotypic differentiation of aphidicolin-selected human neuroblastoma cultures after long-term exposure to nerve growth factor
    • Jensen LM. Phenotypic differentiation of aphidicolin-selected human neuroblastoma cultures after long-term exposure to nerve growth factor. Dev Biol 1987;120:56-64.
    • (1987) Dev Biol , vol.120 , pp. 56-64
    • Jensen, L.M.1
  • 58
    • 0026925580 scopus 로고
    • Neuronal differentiation triggered by blocking cell proliferation
    • LoPresti P, Poluha W, Poluha DK, et al. Neuronal differentiation triggered by blocking cell proliferation. Cell Growth Differ 1992;3:627-635.
    • (1992) Cell Growth Differ , vol.3 , pp. 627-635
    • Lopresti, P.1    Poluha, W.2    Poluha, D.K.3
  • 59
    • 0028814691 scopus 로고
    • TrkA neurogenic receptor regulates differentiation of neuroblastoma cells
    • Poluha W, Poluha DK, Ross AH. TrkA neurogenic receptor regulates differentiation of neuroblastoma cells. Oncogene 1995;10:185-189.
    • (1995) Oncogene , vol.10 , pp. 185-189
    • Poluha, W.1    Poluha, D.K.2    Ross, A.H.3
  • 60
    • 0037076385 scopus 로고    scopus 로고
    • Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype
    • Jögi A, Øra I, Nilsson H, et al. Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype. Proc Natl Acad Sci USA 2002;99:7021-7026.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 7021-7026
    • Jögi, A.1    Øra, I.2    Nilsson, H.3
  • 61
    • 0027517354 scopus 로고
    • Dynamic expression of the murine Achaete-Scute homologue Mash-1 in the developing nervous system
    • Guillemot F, Joyner AL. Dynamic expression of the murine Achaete-Scute homologue Mash-1 in the developing nervous system. Mech Dev 1993;42:171-185.
    • (1993) Mech Dev , vol.42 , pp. 171-185
    • Guillemot, F.1    Joyner, A.L.2
  • 62
    • 0028998474 scopus 로고
    • Constitutive N-myc gene expression inhibits trkA mediated neuronal differentiation
    • Bogenmann E, Torres M, Matsushima H. Constitutive N-myc gene expression inhibits trkA mediated neuronal differentiation. Oncogene 1995;10:1915-1925.
    • (1995) Oncogene , vol.10 , pp. 1915-1925
    • Bogenmann, E.1    Torres, M.2    Matsushima, H.3
  • 63
    • 0023096977 scopus 로고
    • Coordinate changes in neuronal phenotype and surface antigen expression in human neuroblastoma cell variants
    • Rettig WJ, Spengler BA, Chesa PG, et al. Coordinate changes in neuronal phenotype and surface antigen expression in human neuroblastoma cell variants. Cancer Res 1987;47:1383-1389.
    • (1987) Cancer Res , vol.47 , pp. 1383-1389
    • Rettig, W.J.1    Spengler, B.A.2    Chesa, P.G.3
  • 64
    • 0037108268 scopus 로고    scopus 로고
    • N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
    • Knoepfler PS, Cheng PF, Eisenman RN. N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev 2002;16:2699-2712.
    • (2002) Genes Dev , vol.16 , pp. 2699-2712
    • Knoepfler, P.S.1    Cheng, P.F.2    Eisenman, R.N.3
  • 65
    • 0034213414 scopus 로고    scopus 로고
    • N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation
    • Malynn BA, de Alboran IM, O'Hagan RC, et al. N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation. Genes Dev 2000;14:1390-1399.
    • (2000) Genes Dev , vol.14 , pp. 1390-1399
    • Malynn, B.A.1    De Alboran, I.M.2    O'Hagan, R.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.