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Koenig, W.1
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55
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0032894713
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High sensitivity C-reactive protein (hs-CRP): A novel risk marker in cardiovascular disease
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Morrow DA, Ridker PM. High sensitivity C-reactive protein (hs-CRP): a novel risk marker in cardiovascular disease. Prev. Cardiol. 1, 13-16 (1999).
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Prev. Cardiol.
, vol.1
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Morrow, D.A.1
Ridker, P.M.2
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56
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0035799331
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High-sensitivity C-reactive protein: Potential adjunct for global risk assessment in the primary prevention of cardiovascular disease
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Ridker PM. High-sensitivity C-reactive protein: potential adjunct for global risk assessment in the primary prevention of cardiovascular disease. Circulation 103, 1813-1818 (2001).
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(2001)
Circulation
, vol.103
, pp. 1813-1818
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Ridker, P.M.1
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57
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0037469177
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Clinical application of C-reactive protein for cardiovascular disease detection and prevention
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Ridker PM. Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation 107, 363-369 (2003).
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Circulation
, vol.107
, pp. 363-369
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Ridker, P.M.1
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58
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17544390219
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C-reactive protein: A simple test to help predict risk of heart attack and stroke
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Ridker PM. C-reactive protein: a simple test to help predict risk of heart attack and stroke. Circulation 108, E81-E85 (2003). Concise and readable summary of the case for CRP screening in CVD.
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(2003)
Circulation
, vol.108
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Ridker, P.M.1
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59
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0035148488
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Proposed cardiovascular risk assessment algorithm using high-sensitivity C-reactive protein and lipid screening
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Rifai N, Ridker PM. Proposed cardiovascular risk assessment algorithm using high-sensitivity C-reactive protein and lipid screening. Clin. Chem. 47, 28-30 (2001).
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(2001)
Clin. Chem.
, vol.47
, pp. 28-30
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Rifai, N.1
Ridker, P.M.2
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60
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0033545342
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Acute-phase proteins and other systematic responses to inflammation
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Gabay C, Kushner I. Acute-phase proteins and other systematic responses to inflammation. N. Engl. J. Med. 340, 448-454 (1999).
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N. Engl. J. Med.
, vol.340
, pp. 448-454
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Gabay, C.1
Kushner, I.2
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61
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0034023532
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Function of C-reactive protein
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Du Clos TW. Function of C-reactive protein. Ann. Med. 32, 274-278 (2000).
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Ann. Med.
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Du Clos, T.W.1
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62
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0036239880
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C-reactive protein and myocardial infarction
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Sakkinen P, Abbott RD, Curb JD et al. C-reactive protein and myocardial infarction. J. Clin. Epidemiol. 55, 445-451 (2002). The first and one of the few papers on CRP and myocardial infarction (MI) in a minority population (Asian-Americans). Demonstrates roughly equivalent risk of high CRP for MI compared with Caucasians.
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J. Clin. Epidemiol.
, vol.55
, pp. 445-451
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Sakkinen, P.1
Abbott, R.D.2
Curb, J.D.3
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63
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0030956673
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Inflammation, aspirin and the risk of cardiovascular disease in apparently healthy men
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Ridker PM, Cushman M, Stampfer MJ et al. Inflammation, aspirin and the risk of cardiovascular disease in apparently healthy men. N. Engl. J. Med. 336, 973-979 (1997). Classic early paper on CRP and CVD. Also shows CRP is lower in regular users of aspirin.
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(1997)
N. Engl. J. Med.
, vol.336
, pp. 973-979
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Ridker, P.M.1
Cushman, M.2
Stampfer, M.J.3
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64
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0032501991
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Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease
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Ridker PM, Cushman M, Stampfer MJ et al. Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease. Circulation 97, 425-428 (1998).
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(1998)
Circulation
, vol.97
, pp. 425-428
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Ridker, P.M.1
Cushman, M.2
Stampfer, M.J.3
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65
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0029810933
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Relation of C-reactive protein and coronary heart disease in the MRFIT nested case-control study
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Kuller LH, Tracy RP, Shaten J et al. Relation of C-reactive protein and coronary heart disease in the MRFIT nested case-control study. Am J. Epidemiol. 144, 537-547 (1996).
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Am J. Epidemiol.
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Kuller, L.H.1
Tracy, R.P.2
Shaten, J.3
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66
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0034704893
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C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
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Ridker PM, Hennekens CH, Buring JE et al. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N. Engl. J. Med. 342, 836-843 (2000). High impact paper showing that CRP was more predictive than cholesterol screening for CVD in women.
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(2000)
N. Engl. J. Med.
, vol.342
, pp. 836-843
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Ridker, P.M.1
Hennekens, C.H.2
Buring, J.E.3
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67
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0030979827
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Relationship of C-reactive protein to the risk of cardiovascular disease in the elderly
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Tracy RP, Lemaitre RN, Psaty BM et al. Relationship of C-reactive protein to the risk of cardiovascular disease in the elderly. Arterioscler. Thromb. Vasc. Biol. 17, 1121-1127 (1997). One of the few studies of CRP and CVD in the elderly.
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Arterioscler. Thromb. Vasc. Biol.
, vol.17
, pp. 1121-1127
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Tracy, R.P.1
Lemaitre, R.N.2
Psaty, B.M.3
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68
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0242610488
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Inflammatory markers and onset of cardiovascular events: Results from the Health ABC study
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Cesari M, Penninx BW, Newman AB et al. Inflammatory markers and onset of cardiovascular events: results from the Health ABC study. Circulation 108, 2317-2322 (2003). One of the few studies of CRP and CVD in the elderly. Suggests that interleukin-6 may be a better marker than CRP for stroke risk in the elderly.
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(2003)
Circulation
, vol.108
, pp. 2317-2322
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Cesari, M.1
Penninx, B.W.2
Newman, A.B.3
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69
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0035955760
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Novel clinical nmrkers of vascular wall inflammation
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Blake GJ, Ridker PM. Novel clinical nmrkers of vascular wall inflammation. Circ. Res. 89, 763-771 (2001).
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(2001)
Circ. Res.
, vol.89
, pp. 763-771
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Blake, G.J.1
Ridker, P.M.2
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70
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0035897688
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Novel risk factors for systemic atherosclerosis: A comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein (a) and standard cholesterol screening as predictors of peripheral arterial disease
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Ridker PM, Stampfer MJ, Rifai N. Novel risk factors for systemic atherosclerosis: a comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein (a) and standard cholesterol screening as predictors of peripheral arterial disease. JAMA 285, 2481-2485 (2001). Excellent comparison of the relative predictive abilities of different novel risk factors for atherosclerosis suggesting that CRP is more predictive than other novel risk factors and a better screening tool.
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(2001)
JAMA
, vol.285
, pp. 2481-2485
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Ridker, P.M.1
Stampfer, M.J.2
Rifai, N.3
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71
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0032568486
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C-reactive protein adds to the predictive value of total and HDL cholesterol in determining risk of first myocardial infarction
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Ridker PM, Glynn RJ, Hennekens CH. C-reactive protein adds to the predictive value of total and HDL cholesterol in determining risk of first myocardial infarction. Circulation 97, 2007-2011 (1998).
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(1998)
Circulation
, vol.97
, pp. 2007-2011
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Ridker, P.M.1
Glynn, R.J.2
Hennekens, C.H.3
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72
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0037322541
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Clinical use of C-reactive protein for prognostic stratification in ischemic stroke: Has the time come for including it in the patient risk profile?
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Di Napoli M, Papa E Clinical use of C-reactive protein for prognostic stratification in ischemic stroke: has the time come for including it in the patient risk profile? Stroke 34, 375 (2003).
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(2003)
Stroke
, vol.34
, pp. 375
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Di Napoli, M.1
Papa, E.2
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73
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0037022237
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Weight loss reduced C-reactive protein levels in obese postmenopausal women
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Tchernof A, Noran A, Sites CK et al. Weight loss reduced C-reactive protein levels in obese postmenopausal women. Circulation 105, 564-569 (2002).
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(2002)
Circulation
, vol.105
, pp. 564-569
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Tchernof, A.1
Noran, A.2
Sites, C.K.3
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74
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0037469232
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Markers of inflammation and cardiovascular disease: Application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association
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Pearson TA, Mensah GA, Alexander RW et al. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation 107, 499-511 (2003). Comprehensive evidence-based summary statement and guidelines for health professionals regarding CRP testing.
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(2003)
Circulation
, vol.107
, pp. 499-511
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Pearson, T.A.1
Mensah, G.A.2
Alexander, R.W.3
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75
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0032566401
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Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women
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Ridker PM, Buring JE, Shih J et al. Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women. Circulation 98, 731-733 (1998).
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(1998)
Circulation
, vol.98
, pp. 731-733
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Ridker, P.M.1
Buring, J.E.2
Shih, J.3
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76
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0035211591
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Should statin therapy be considered for patients with elevated C-reactive protein? The need for a definitive clinical trial
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Ridker PM. Should statin therapy be considered for patients with elevated C-reactive protein? The need for a definitive clinical trial. Eur. Heart J. 22, 2135-2137 (2001).
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(2001)
Eur. Heart J.
, vol.22
, pp. 2135-2137
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Ridker, P.M.1
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77
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0033587667
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Long-term effects of pravastatin on plasma concentration of C-reactive protein
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Ridker PM, Rifai N, Pfeffer M et al. Long-term effects of pravastatin on plasma concentration of C-reactive protein. Circulation 100, 230-235 (1999). Good paper showing statins can be effective in lowering CRP and thus may play a role in reducing inflammation.
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(1999)
Circulation
, vol.100
, pp. 230-235
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Ridker, P.M.1
Rifai, N.2
Pfeffer, M.3
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78
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0035885045
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Effect of clopidogrel added to aspirin before percutaneous coronary intervention on the risk associated with C-reactive protein
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Chew D, Bhatt DL, Robbins MA et al. Effect of clopidogrel added to aspirin before percutaneous coronary intervention on the risk associated with C-reactive protein. Am. J. Cardiol. 88, 672-674 (2001).
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(2001)
Am. J. Cardiol.
, vol.88
, pp. 672-674
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Chew, D.1
Bhatt, D.L.2
Robbins, M.A.3
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79
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0035838353
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Abciximab suppresses the rise in levels of circulating inflammatory markers after percutaneous coronary revascularization
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Lincoff AM, Kereiakes DJ, Mascelli MA et al. Abciximab suppresses the rise in levels of circulating inflammatory markers after percutaneous coronary revascularization. Circulation 104, 163-167 (2001).
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(2001)
Circulation
, vol.104
, pp. 163-167
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Lincoff, A.M.1
Kereiakes, D.J.2
Mascelli, M.A.3
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80
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0037031267
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Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with Type 2 diabetes mellitus
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Haffner SM, Greenberg AS, Weston WM et al. Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with Type 2 diabetes mellitus. Circulation 106, 679-684 (2002). Interesting paper showing that the glitazones may also play a role in reducing inflammation and that CRP may be linked to glycemic control.
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(2002)
Circulation
, vol.106
, pp. 679-684
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Haffner, S.M.1
Greenberg, A.S.2
Weston, W.M.3
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81
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0034688194
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Effects of an angiotensin-converting-enzyme inhibitor, Ramipril, on cardiovascular events in high-risk patients
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The Heart Outcomes Prevention Evaluation Study Investigators. Effects of an angiotensin-converting-enzyme inhibitor, Ramipril, on cardiovascular events in high-risk patients. N. Engl. J. Med. 342, 145-153 (2000).
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N. Engl. J. Med.
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82
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0032710356
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Clinical efficacy of an automated high-sensitivity C-reactive protein assay
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Rifai N, Tracy RP, Ridker PM. Clinical efficacy of an automated high-sensitivity C-reactive protein assay. Clin. Chem. 45, 2136-2141 (1999).
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(1999)
Clin. Chem.
, vol.45
, pp. 2136-2141
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Rifai, N.1
Tracy, R.P.2
Ridker, P.M.3
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83
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0034034469
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Evaluation of four automated high-sensitivity C-reactive protein methods: Implications for clinical and epidemiological applications
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Roberts WL, Sedrick R, Moulton L et al. Evaluation of four automated high-sensitivity C-reactive protein methods: implications for clinical and epidemiological applications. Clin. Chem. 46 461-468 (2000).
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Clin. Chem.
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Roberts, W.L.1
Sedrick, R.2
Moulton, L.3
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84
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0037078969
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Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events
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Ridker PM, Rifai N, Rose L et al. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N. Engl. J. Med. 347, 1557-1565 (2002). Good paper making the case that CRP may be more predictive than cholesterol for CVD.
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(2002)
N. Engl. J. Med.
, vol.347
, pp. 1557-1565
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Ridker, P.M.1
Rifai, N.2
Rose, L.3
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85
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0035806626
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Effect of statin therapy on C-reactive protein levels: The Pravastatin Inflammation CRP Evaluation (PRINCE)
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Albert MA, Danielson E, Rifai N et al. Effect of statin therapy on C-reactive protein levels: the Pravastatin Inflammation CRP Evaluation (PRINCE). JAMA 286, 64-70 (2001).
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(2001)
JAMA
, vol.286
, pp. 64-70
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Albert, M.A.1
Danielson, E.2
Rifai, N.3
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86
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0037126043
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Simvastatin lowers C-reactive protein within 14 days: An effect independent of low-density lipoprotein cholesterol reduction
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Plenge JK, Hernandez TL, Weil KM et al. Simvastatin lowers C-reactive protein within 14 days: an effect independent of low-density lipoprotein cholesterol reduction. Circulation 106, 1447-1452 (2002).
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(2002)
Circulation
, vol.106
, pp. 1447-1452
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Plenge, J.K.1
Hernandez, T.L.2
Weil, K.M.3
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87
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0038455708
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Effects of a dietary portfolio of cholesterol-lowering foods vs. lovastatin on serum lipids and C-reactive protein
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Jenkins DJ, Kendall CW, Marchie A et al. Effects of a dietary portfolio of cholesterol-lowering foods vs. lovastatin on serum lipids and C-reactive protein. JAMA 290, 502-510 (2003). Excellent paper showing the powerful effects of specific dietary compounds in lowering lipids and CRP equivalent in efficacy to first generation statins.
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(2003)
JAMA
, vol.290
, pp. 502-510
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Jenkins, D.J.1
Kendall, C.W.2
Marchie, A.3
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88
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10744225336
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Strikingly low circulating CRP concentrations in ultramarathon runners independent of markers of adiposity: How low can you go?
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Tomaszewski M, Charchar FJ, Przybycin M et al. Strikingly low circulating CRP concentrations in ultramarathon runners independent of markers of adiposity: how low can you go? Arterioscler. Thromb. Vasc. Biol. 23, 1640-1644 (2003). Provocative paper showing that exercise may lower CRP levels independent of body fat loss.
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(2003)
Arterioscler. Thromb. Vasc. Biol.
, vol.23
, pp. 1640-1644
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Tomaszewski, M.1
Charchar, F.J.2
Przybycin, M.3
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89
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0037320943
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Stroke genetics update
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Alberts MJ. Stroke genetics update. Stroke 34, 342-344 (2003). Good current and concise review of this topic.
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(2003)
Stroke
, vol.34
, pp. 342-344
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Alberts, M.J.1
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90
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New players in the genetics of stroke
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Tournier-Lasserve E. New players in the genetics of stroke. N. Engl. J. Med. 347, 1711-1712 (2002).
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N. Engl. J. Med.
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, pp. 1711-1712
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Tournier-Lasserve, E.1
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91
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10744231062
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Human CRP gene polymorphism influences CRP levels: Implications for the prediction and pathogenesis of coronary heart disease
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Brull DJ, Serrano N, Zito F et al. Human CRP gene polymorphism influences CRP levels: implications for the prediction and pathogenesis of coronary heart disease. Arterioscler. Thromb. Vasc. Biol. 11, 2063-2069 (2003). Important new information on how subtle variations in human genes might affect CVD risk through variation in CRP levels.
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(2003)
Arterioscler. Thromb. Vasc. Biol.
, vol.11
, pp. 2063-2069
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Brull, D.J.1
Serrano, N.2
Zito, F.3
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92
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Toyoda K, Chu Y, Heistad DD. Gene therapy for cerebral vascular disease: update 2003. Br. J. Pharmacol. 139, 1-9 (2003).
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Br. J. Pharmacol.
, vol.139
, pp. 1-9
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Toyoda, K.1
Chu, Y.2
Heistad, D.D.3
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