Early major ischemic changes on computed tomography should not preclude use of tissue plasminogen activator

Stroke

Volumn 34, Issue 3, 2003, Pages 821-822

  Lyden, Patrick ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Brain ischemia; Computed tomography; Tissue plasminogen activator

Indexed keywords

FIBRINOLYTIC AGENT; TISSUE PLASMINOGEN ACTIVATOR;

BRAIN EDEMA; BRAIN HEMORRHAGE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN PERFUSION; COMPUTER ASSISTED TOMOGRAPHY; DISABILITY; GRAY MATTER; HUMAN; MORTALITY; PRIORITY JOURNAL; SHORT SURVEY; STROKE; TISSUE INJURY; WHITE MATTER;

BRAIN; BRAIN EDEMA; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; DISEASE PROGRESSION; HUMANS; PREDICTIVE VALUE OF TESTS; RECOVERY OF FUNCTION; RISK ASSESSMENT; RISK FACTORS; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0037337601     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000059431.80687.D8     Document Type: Short Survey

References (6)

1. von Kummer R, Allen KL, Holle R, Bozzao L, Bastianello S, Manelfe C. Acute stroke: usefulness of early CT findings before thrombolytic therapy. Radiology, 1997;205:327-333.
2. NINDS rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995;333:1581-1587.
3. Grotta J, Chiu D, Lu M, Patel S, Levine S, Tilley B, Brott T, Haley EC Jr, Lyden P, Kothari R, et al. Agreement and variability in the interpretation of early CT changes in stroke patients qualifying for intravenous rtPA therapy. Stroke. 1999;30:1528-1233.
4. von Kummer R, Bourguain H, Bastianello S, Bozzao L, Manelfe C, Meier D, Hacke W, for the European Cooperative Acute Stroke Study II Group. Early prediction of irreversible brain damage, after ischemic stroke at CT. Radiology. 2001;219:95-100.
5. Patel SC, Levine SR, Tilley BC, Grotta JC, Lu M, Frankel M, Haley EC, Brott TG, Broderick JP, Horowitz S, et al, for the National Institute of Neurological Disorders, and Stroke rt-PA Stroke Study Group. Lack of clinical significance of early ischemic changes on computed tomography in acute stroke. JAMA. 2001;286:2830-2838.
6. Gilligan A, Markus R, Read S, Srikanth V, Hirano T, Fitt G, Arends M, Chambers BR, Davis SM, Donnan GA. Australian Streptokinase Trial Investigators. Baseline blood pressure but not early computed tomography changes predicts major hemorrhage after streptokinase in acute ischemic stroke. Stroke. 2002;33:2236-2242.