Targeting internal ribosome entry site (IRES)-mediated translation to block hepatitis C and other RNA viruses

FEMS Microbiology Letters

Volumn 234, Issue 2, 2004, Pages 189-199

  Dasgupta, Asim ^a   Das, Saumitra ^a,b   Izumi, Raquel ^a,c   Venkatesan, Arun ^a,d   Barat, Bhaswati ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INDIAN INSTITUTE OF SCIENCE   (India)

^c AMGEN INC   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antivirals; Hepatitis C virus; IRES mediated translation; RNA viruses

Indexed keywords

ALANYLALANYLLEUCYLGLUTAMINYLALANYLLYSYLISOLEUCYLCYSTEINYLHISTIDYLGLUTAMINYL ISOLEUCYLGLUTAMINYLTYROSYLTYROSYLPHENYLALANYLGLYCYLGLUTAMINYLPHENYLALANINE; ALANYLALANYLLEUCYLGLUTAMYLALANYLGLUTAMINYLISOLEUCYLCYSTEINYLGLUTAMINYLGLUTA MINYLISOLEUCYLGLUTAMYLTYROSYLTYROSYLPHENYLALANYLGLYCYLASPARTYLPHENYLALANINE; ALANYLALANYLLEUCYLGLUTAMYLALANYLLYSYLISOLEUCYLCYSTEINYLHISTIDYLGLUTAMINYLIS OLEUCYLGLUTAMYLGLUTAMINYLGLUTAMINYLGLUTAMINYLGLYCYLASPARTYLGLUTAMINE; ALANYLALANYLLEUCYLGLUTAMYLALANYLLYSYLISOLEUCYLCYSTEINYLHISTIDYLGLUTAMINYLIS OLEUCYLGLUTAMYLGLUTAMINYLGLUTAMINYLPHENYLALANYLGLYCYLASPARTYLPHENYLALANINE; ALANYLALANYLLEUCYLGLUTAMYLALANYLLYSYLISOLEUCYLCYSTEINYLHISTIDYLGLUTAMINYLIS OLEUCYLGLUTAMYLGLUTAMINYLTYROSYLPHENYLALANYLGLYCYLASPARTYLPHENYLALANINE; ALANYLALANYLLEUCYLGLUTAMYLALANYLLYSYLISOLEUCYLCYSTEINYLHISTIDYLGLUTAMINYLIS OLEUCYLGLUTAMYLTYROSYLGLUTAMINYLPHENYLALANYLGLYCYLASPARTYLPHENYLALANINE; ALANYLALANYLLEUCYLGLUTAMYLALANYLLYSYLISOLEUCYLCYSTEINYLHISTIDYLGLUTAMINYLIS OLEUCYLGLUTAMYLTYROSYLTYROSYLGLUTAMINYLGLYCYLASPARTYLPHENYLALANINE; ALANYLALANYLLEUCYLGLUTAMYLALANYLLYSYLISOLEUCYLCYSTEINYLHISTIDYLGLUTAMINYLIS OLEUCYLGLUTAMYLTYROSYLTYROSYLPHENYLALANYLGLYCYLASPARTYLGLUTAMINE; ALANYLALANYLLEUCYLGLUTAMYLALANYLLYSYLISOLEUCYLCYSTEINYLHISTIDYLGLUTAMINYLIS OLEUCYLGLUTAMYLTYROSYLTYROSYLPHENYLALANYLGLYCYLASPARTYLPHENYLALANINE; ALANYLALANYLLEUCYLGLUTAMYLALANYLLYSYLISOLEUCYLCYSTEINYLHISTIDYLGLUTAMINYLIS OLEUCYLGLUTAMYLTYROSYLTYROSYLPHENYLGLUTAMINYLGLYCYLASPARTYLGLUTAMINE; ANTIVIRUS AGENT; FUNGAL RNA; GLUTAMINYLGLUTAMINYLGLUTAMINYLGLUTAMYLALANYLLYSYLISOLEUCYLCYSTEINYLHISTIDYL GLUTAMINYLISOLEUCYLGLUTAMYLTYROSYLTYROSYLPHENYLALANYLGLYCYLASPARTYLPHENYLALANINE; GLUTAMINYLGLUTAMINYLGLUTAMINYLGLUTAMYLGLUTAMINYLLYSYLGLUTAMINYLCYSTEINYLHIS TIDYLGLUTAMINYLISOLEUCYLGLUTAMYLTYROSYLTYROSYLPHENYLALANYLGLYCYLASPARTYLPHENYLAL ANINE; INITIATION FACTOR 2; INITIATION FACTOR 3; LA ANTIGEN; PEPTIDE FRAGMENT; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ACUTE TOXICITY; AFFINITY CHROMATOGRAPHY; COXSACKIE VIRUS; DRUG PROTEIN BINDING; EUKARYOTE; FOOT AND MOUTH DISEASE VIRUS; HEPATITIS A VIRUS; HEPATITIS C VIRUS; HUMAN; INTERNAL RIBOSOME ENTRY SITE; LUPUS VULGARIS; NONHUMAN; PICORNAVIRUS; POLIOMYELITIS VIRUS; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN RNA BINDING; PROTEIN TARGETING; RHINOVIRUS; RIBOSOME; RNA CAPPING; RNA ISOLATION; RNA TRANSLATION; RNA VIRUS; SACCHAROMYCES CEREVISIAE; SHORT SURVEY; STRUCTURE ACTIVITY RELATION; TISSUE DISTRIBUTION; TRANSLATION INITIATION; TRANSLATION REGULATION; VIRUS INHIBITION;

HEPATITIS C VIRUS; POLIOVIRUS; RNA VIRUSES; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 2342566920     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.femsle.2004.03.045     Document Type: Article

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