Intracellular redistribution of truncated La protein produced by poliovirus 3C(pro)-mediated cleavage

Journal of Virology

Volumn 73, Issue 3, 1999, Pages 2193-2200

  Shiroki, Kazuko ^a   Isoyama, Takeshi ^a   Kuge, Shusuke ^a   Ishii, Toshihiko ^a   Ohmi, Shinobu ^a   Hata, Syoji ^a   Suzuki, Koichi ^a   Takasaki, Yoshinari ^b   Nomoto, Akio ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; RNA BINDING PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL LYSATE; CELLULAR DISTRIBUTION; HUMAN; HUMAN CELL; POLIOMYELITIS VIRUS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROCESSING; RETICULOCYTE; TRANSLATION INITIATION; VIRUS INFECTION; VIRUS REPLICATION;

EID: 0032978965     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.3.2193-2200.1999     Document Type: Article

References (50)

1. Ali, N., and A. Siddiqui. 1997. The La antigen binds 5′ noncoding region of the hepatitis C virus RNA in the context of the initiator AUG codon and stimulates internal ribosome entry site-mediated translation. Proc. Natl. Acad. Sci. USA 94:2249-2254.
2. Andino, R., G. E. Rieckhof, P. L. Achacoso, and D. Baltimore. 1993. Poliovirus RNA synthesis utilizes an RNP complex formed around the 5′-end of viral RNA. EMBO J. 12:3587-3598.
3. Bachmann, M., S. Chang, H. Słor, J. Kukulies, and W. E. G. Müller. 1990. Shuttling of the autoantigen La between nucleus and cell surface after UV irradiation of human keratinocytes. Exp. Cell Res. 191:171-180.
4. Bachmann, M., K. Pfeifer, H. C. Schröder, and W. E. G. Müller. 1989. The La antigen shuttles between the nucleus and the cytoplasm in CV-1 cells. Mol. Cell. Biochem. 85:103-114.
5. Bachmann, M., K. Pfeifer, H. C. Schröder, and W. E. G. Müller. 1990. Characterization of the autoantigen La as a nucleic acid-dependent ATPase/dATPase with melting properties. Cell 60:85-93.
6. Belsham, G. J., N. Sonenberg, and Y. V. Svitkin. 1989. The role of the La autoantigen in internal initiation. Curr. Top. Microbiol. Immunol. 203:85-98.
7. Blyn, L. B., J. S. Towner, B. L. Semler, and E. Ehrenfeld. 1997. Requirement of poly(rC) binding protein 2 for translation of poliovirus RNA. J. Virol. 71: 6243-6246.
8. Brown, B. A., and E. Ehrenfeld. 1979. Translation of poliovirus RNA in vitro: changes in cleavage pattern and initiation sites by ribosomal salt wash. Virology 97:396-405.
9. Chang, Y.-N., D. J. Kenan, J. D. Keene, A. Gatignol, and K.-T. Jeang. 1994. Direct interactions between autoantigen La and human immunodeficiency virus leader RNA. J. Virol. 68:7008-7020.
10. Clark, M. E., P. M. Lieberman, A. J. Berk, and A. Dasgupta. 1993. Direct cleavage of human TATA-binding protein by poliovirus protease 3C in vivo and in vitro. Mol. Cell. Biol. 13:1232-1237.
11. Cormack, B. P., R. H. Valdivia, and S. Falkow. 1996. FACS-optimized mutants of the green fluorescent protein (GFP). Gene 173:33-38.
12. Craig, A. W. B., Y. V. Svitkin, H. S. Lee, G. J. Belsham, and N. Sonenberg. 1997. The La autoantigen contains a dimerization domain that is essential for enhancing translation. Mol. Cell. Biol. 17:163-169.
13. Pro-catalyzed cleavage of human TATA-binding transcription factor TBP. J. Virol. 67:3326-3331.
14. Fan, H., A. L. Sakulich, J. L. Goodier, X. Zhang, J. Qin, and R. J. Maraia. 1997. Phosphorylation of the human La antigen on serine 366 can regulate recycling of RNA polymerase III transcription complexes. Cell 88:707-715.
15. Francoeur, A. M., and M. B. Mathews. 1982. Interaction between VA RNA and the lupus antigen La: formation of a ribonucleoprotein particle in vitro. Proc. Natl. Acad. Sci. USA 79:6772-6776.
16. Gamarnik, A. V., and R. Andino. 1997. Two functional complexes formed by KH domain containing proteins with the 5′ noncoding region of poliovirus RNA. RNA 3:882-892.
17. Goodier, J. L., H. Fan, and R. J. Maraia. 1997. A carboxy-terminal basic region controls RNA polymerase III transcription factor activity of human La protein. Mol. Cell. Biol. 17:5823-5832.
18. Görlich, D. 1998. Transport into and out of the cell nucleus. EMBO J. 17: 2721-2727.
19. Hellen, C. U. T., G. W. Witherell, M. Schmid, S. H. Shin, T. V. Pestova, A. Gil, and E. Wimmer. 1993. A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein. Proc. Natl. Acad. Sci. USA 90: 7642-7646.
20. Hühn, P., G. J. M. Pruijn, W. J. van Venrooij, and M. Bachmann. 1997. Characterization of the autoantigen La (SS-B) as a dsRNA unwinding enzyme. Nucleic Acids Res. 25:410-416.
21. Ishii, T., K. Shiroki, D.-H. Hong, T. Aoki, Y. Ohta, S. Abe, S. Hashizume, and A. Nomoto. 1998. A new internal ribosomal entry site 5′ boundary is required for poliovirus translation initiation in a mouse system. J. Virol. 72:2398-2405.
22. Joachims, M., K. S. Harris, and D. Etchison. 1995. Poliovirus protease 3C mediates cleavage of microtubule-associated protein 4. Virology 211:451-461.
23. Kanegae, Y., K. Takamori, Y. Sato, G. Lee, M. Nakai, and I. Saito. 1996. Efficient gene activation system on mammalian cell chromosomes using recombinant adenovirus producing Cre recombinase. Gene 181:207-212.
24. Kobayashi, M., S. Nagata, Y. Kita, N. Nakatsu, S. Ihara, K. Kaibuchi, S. Kuroda, M. Ui, H. Iba, H. Konishi, U. Kikkawa, I. Saitoh, and Y. Fukui. 1997. Expression of a constitutively active phosphatidylinositol 3-kinase induces process formation in rat PC12 cells. J. Biol. Chem. 272:16089-16092.
25. Kräusslich, H. G., M. J. H. Nicklin, H. Toyoda, D. Etchison, and E. Wimmer. 1987. Poliovirus proteinase 2A induces cleavage of eucaryotic initiation factor 4F polypeptide p220. J. Virol. 61:2711-2718.
26. Kuge, S., N. Jones, and A. Nomoto. 1997. Regulation of yAp-1 nuclear localization in response to oxidative stress. EMBO J. 16:1710-1720.
27. Kurilla, M. G., and J. D. Keene. 1983. The leader RNA of vesicular stomatitis virus is bound by a cellular protein reactive with anti-La lupus antibodies. Cell 34:837-845.
28. Lai, M. M. C. 1998. Cellular factors in the transcription and replication of viral RNA genomes: A parallel to DNA-dependent RNA transcription. Virology 244:1-12.
29. Lawson, M. A., and B. L. Semler. 1991. Poliovirus thiol proteinase 3C can utilize a serine nucleophile within the putative catalytic triad. Proc. Natl. Acad. Sci. USA 88:9919-9923.
30. Maraia, R. J. 1996. Transcription termination factor La is also an initiation factor for RNA polymerase III. Proc. Natl. Acad. Sci. USA 93:3383-3387.
31. Maraia, R. J., D. J. Kenan, and J. D. Keene. 1994. Eukaryotic transcription termination factor La mediates transcript release and facilitates reinitiation by RNA polymerase III. Mol. Cell. Biol. 14:2147-2158.
32. Meerovitch, K., J. Pelletier, and N. Sonenberg. 1989. A cellular protein that binds to the 5′-noncoding region of poliovirus RNA: implication for internal translation initiation. Genes Dev. 3:1026-1034.
33. Meerovitch, K., Y. V. Svitkin, H. S. Lee, F. Lejbkowicz, D. J. Kenan, E. K. L. Chan, V. I. Agol, J. D. Keene, and N. Sonenberg. 1993. La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate. J. Virol. 67:3798-3807.
34. Nicklin, M. J., H. G. Kräusslich, H. Toyoda, J. J. Dunn, and E. Wimmer. 1987. Poliovirus polypeptide precursors: expression in vitro and processing by exogenous 3C and 2A proteinase. Proc. Natl. Acad. Sci. USA 84:4002-4006.
35. Peek, R., G. J. M. Pruijn, and W. J. van Venrooij. 1996. Interaction of the La (SS-B) autoantigen with small ribosomal subunits. Eur. J. Biochem. 236:649-655.
36. Pruijn, G. J., J. P. H. Thijssen, P. R. Smith, D. G. Williams, and W. J. van Venrooij. 1995. Anti-La monoclonal antibodies recognizing epitopes within the RNA-binding domain of the La protein show differential capacities to immunoprecipitate RNA-associated La protein. Eur. J. Biochem. 232:611-619.
37. Rosa, M. D., E. Gottlieb, M. R. Lerner, and J. A. Steitz. 1981. Striking similarities are exhibited by two small Epstein-Barr virus-encoded ribonucleic acids and the adenovirus-associated ribonucleic acids VAI and VAII. Mol. Cell. Biol. 1:785-796.
38. Shiroki, K., T. Ishii, T. Aoki, M. Kobashi, S. Ohka, and A. Nomoto. 1995. A new cis-acting element for RNA replication within the 5′ noncoding region of poliovirus type 1 RNA. J. Virol. 69:6825-6832.
39. Shiroki, K., T. Ishii, T. Aoki, Y. Ota, W.-X. Yang, T. Komatsu, Y. Ami, M. Arita, S. Abe, S. Hashizume, and A. Nomoto. 1997. Host range phenotype induced by mutations in the internal ribosomal entry site of poliovirus RNA. J. Virol. 71:1-8.
40. Siemering, K. R., R. Golbik, R. Sever, and J. Haseloff. 1996. Mutations that suppress the thermosensitivity of green fluorescent protein. Curr. Biol. 6: 1653-1663.
41. Simons, F. H. M., F. J. M. Broers, W. J. van Venrooij, and G. J. M. Pruijn. 1996. Characterization of cis-acting signals for nuclear import and retention of the La (SS-B) autoantigen. Exp. Cell Res. 224:224-236.
42. Simons, F. H., S. A. Rutjes, W. J. van Venrooij, and G. J. Pruijn. 1996. The interactions with Ro60 and La differentially affect nuclear export of hY1 RNA. RNA 2:264-273.
43. Stefano, J. E. 1984. Purified lupus antigen La recognizes an oligouridylate stretch common to the 3′ termini of RNA polymerase III transcripts. Cell 36: 145-154.
44. Svitkin, Y. V., K. Meerovitch, H. S. Lee, J. N. Dholakia, D. J. Kenan, V. I. Agol, and N. Sonenberg. 1994. Internal translation initiation on poliovirus RNA: further characterization of La function in poliovirus translation in vitro. J. Virol. 68:1544-1550.
45. Tröster, H., H. Bartsch, R. Klein, T. E. Metzger, G. Pollak, I. Semsei, M. Schwemmte, Ger J. M. Pruijn, W. J. van Venrooij, and M. Bachmann. 1995. Activation of a murine autoreactive B cell by immunization with human recombinant autoantigen La/SS-B: characterization of the autoepitope. J. Autoimmun. 8:825-842.
46. Tröster, H., T. E. Metzger, I. Semsei, M. Schwemmle, A. Winterpacht, B. Zabel, and M. Bachmann. 1994. One gene, two transcripts: isolation of an alternative transcript encoding for the autoantigen La/SS-B from a cDNA library of a patient with primary Sjögrens' syndrome. J. Exp. Med. 180:2059-2067.
47. Willis, I. M. 1993. RNA polymerase III. Genes, factors and transcriptional specificity. Eur. J. Biochem. 212:1-11.
48. Xiao, Q., T. V. Sharp, I. W. Jeffrey, M. C. James, G. J. Pruijn, W. J. van Venrooij, and M. J. Clemens. 1994. The La antigen inhibits the activation of the interferon-inducible protein kinase PKR by sequestering and unwinding double-stranded RNA. Nucleic Acids Res. 22:2512-2518.
49. pro. J. Virol. 71:1220-1226.
50. pro. Virology 239:176-185.