Revertant analysis of J-K mutations in the encephalomyocarditis virus internal ribosomal entry site detects an altered leader protein

Journal of Virology

Volumn 70, Issue 9, 1996, Pages 6425-6430

  Hoffman, Michael A ^a   Palmenberg, Ann C ^b,c  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c Dept Anim Hlth and Biomed Sci ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SIGNAL PEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ENCEPHALOMYOCARDITIS VIRUS; NONHUMAN; PRIORITY JOURNAL; RIBOSOME; VIRUS MUTATION; VIRUS TRANSCRIPTION;

EID: 0029845379     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.9.6425-6430.1996     Document Type: Article

References (22)

1. Belsham, G. J., and J. K. Brangwyn. 1990. A region of the 5′ noncoding region of foot-and-mouth disease virus RNA directs efficient internal initiation of protein synthesis within cells: involvement with the role of L protease in translational control. J. Virol. 64:5389-5395.
2. Borman, A., and R. J. Jackson. 1992. Initiation of translation of human rhinovirus RNA:mapping the internal ribosome entry site. Virology 188: 685-696.
3. Chen, H.-H., W.-P. Kong, and R. P. Roos. 1995. The leader peptide of Theiler's murine encephalomyelitis virus is a zinc-binding protein. J. Virol. 69:8076-8078.
4. Dildine, S. L., and B. L. Semler. 1988. The deletion of 41 proximal nucleotides reverts a poliovirus mutant containing a temperature-sensitive lesion in the 5′ noncoding region of genomic RNA. J. Virol. 63:847-862.
5. Dildine, S. L., K. R. Stark, A. A. Haller, and B. L. Semler. 1991. Poliovirus translation initiation: differential effects of directed and selected mutations in the 5′ noncoding region of viral RNAs. Virology 182:742-752.
6. Duke, G. M., M. A. Hoffman, and A. C. Palmenberg. 1992. Sequence and structural elements that contribute to efficient encephalomyocarditis viral RNA translation. J. Virol. 66:1602-1609.
7. Duke, G. M., J. E. Osorio, and A. C. Palmenberg. 1990. Attenuation of mengovirus through genetic engineering of the 5′ noncoding poly(C) tract. Nature (London) 343:474-476.
8. Duke, G. M., and A. C. Palmenberg. 1989. Cloning and synthesis of infectious cardiovirus RNAs containing short, discrete poly(C) tracts. J. Virol. 63:1822-1826.
9. Hoffman, M. A., and A C. Palmenberg. 1995. Mutational analysis of the J-K stem-loop region of the encephalomyocarditis virus IRES. J. Virol. 69:4399-4406.
10. Jackson, R. J., and A. Kaminski. 1995. Internal initiation of translation in eucaryotes: the picornavirus paradigm and beyond. RNA 1:985-1000.
11. Jang, S. K., H. G. Krausslich, M. J. H. Nicklin, G. M. Duke, A. C. Palmenberg, and E. Wimmer. 1988. A segment of the 5′ nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. J. Virol. 62:2636-2643.
12. Meerovitch, K., Y. V. Svitkin, H. S. Lee, F. Lejbkowicz, D. J. Kenan, E. K. L. Chan, V. I. Agol, J. D. Keene, and N. Sonenberg. 1993. La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate. J. Virol. 67:3798-3807.
13. Palmenberg, A. C. 1982. In vitro synthesis and assembly of picornaviral capsid intermediate structures. J. Virol. 44:900-906.
14. Pelham, H. R. B., and R. J. Jackson. 1976. An efficient mRNA-dependent translation system from reticulocyte lysates. Eur. J. Biochem. 67:247-256.
15. Pelletier, J., and N. Sonenberg. 1988. Internal initiation of translation of eukatyotic mRNA by a sequence derived from poliovirus RNA. Nature (London) 334:320-325.
16. Pilipenko, E. V., V. M. Blinov, T. M. Dmitrieva, and V. I. Agol. 1989. Conservation of the secondary structure elements of the 5′-untranslated region of cardio- and aphthovirus RNAs. Nucleic Acids Res. 17:5701-5711.
17. Pilipenko, E. V., V. M. Blinov, L. I. Romanova, A. N. Sinyakov, S. V. Maslova, and V. I. Agol. 1989. Conserved structural domains in the 5′-untranslated region of picornaviral genomes: an analysis of the segment controlling translation and neurovirulence. Virology 168:201-209.
18. Pilipenko, E.V., A. P. Gmyl, S. V. Maslova, Y. V. Svitkin, A. N. Sinyakov, and V. I. Agol. 1992. Prokaryotic-like cis elements in the cap-independent internal initiation of translation on picornavirus RNA. Cell 68:119-132.
19. Rueckert, R. R., and M. A. Pallansch. 1981. Preparation and characterization of encephalomyocarditis virus. Methods Enzymol. 78:315-325.
20. Scheper, G. C., A. A. Thomas, and H. O. Voorma. 1991. The 5′ untranslated region of encephalomyocarditis virus contains a sequence for very efficient binding of eukaryotic initiation factor eIF-2/2B. Biochim. Biophys. Acta 1089:220-226.
21. Svitkin, Y. V., N. Cammack, P. D. Minor, and J. W. Almond. 1990. Translation deficiency of the Sabin type 3 poliovirus genome: association with an attenuating mutation C472 to U. Virology 175:103-109.
22. Witherell, G. W., A Gil, and E. Wimmer. 1993. Interaction of polypyrimidine tract binding protein with the encephalomyocarditis virus mRNA internal ribosomal entry site. Biochemistry 32:8268-8275.