XPC lymphoblastoid cells defective in the hMutSα DNA mismatch repair complex exhibit normal sensitivity to UVC radiation and normal transcription-coupled excision repair of DNA cyclobutane pyrimidine dimers

DNA Repair

Volumn 3, Issue 6, 2004, Pages 649-657

  Kobayashi, Katsutoshi ^a,c   O'Driscoll, Mark ^a,d   Macpherson, Peter ^a   Mullenders, Leon ^b   Vreeswijk, Maaike ^b,e   Karran, Peter ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF SUSSEX   (United Kingdom)

^e LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Cyclobutane pyrimidine dimers; Global genomic repair; Transcription coupled repair

Indexed keywords

CYCLOBUTANE DERIVATIVE; CYCLOBUTANE PYRIMIDINE; DIMER; DNA; PROTEIN MSH2; PROTEIN MSH6; PROTEIN MUTS; PROTEIN MUTS ALPHA; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; DNA TRANSCRIPTION; EXCISION REPAIR; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL; MISMATCH REPAIR; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; RADIOSENSITIVITY; ULTRAVIOLET C RADIATION; XERODERMA PIGMENTOSUM;

ALKYLATING AGENTS; BASE PAIR MISMATCH; CELLS, CULTURED; DNA REPAIR; DNA-BINDING PROTEINS; DRUG RESISTANCE; HUMANS; LYMPHOCYTES; METHYLNITROSOUREA; MUTS HOMOLOG 2 PROTEIN; PROTO-ONCOGENE PROTEINS; PYRIMIDINE DIMERS; RADIATION TOLERANCE; TRANSCRIPTION, GENETIC; ULTRAVIOLET RAYS;

EID: 2342565083     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2004.02.007     Document Type: Article

References (31)

1. E.C. Friedberg, G.C. Walker, W. Siede, DNA Repair and Mutagenesis, ASM Press, Washington, 1995.
2. Modrich P., Lahue R. Mismatch repair in replication fidelity, genetic recombination and cancer biology. Annu. Rev. Biochem. 65:1996;101-133
3. Peltomäki P. Role of DNA mismatch repair defects in the pathogenesis of human cancer. J. Clin. Oncol. 21:2003;1174-1179
4. Jiricny J., Nyström-Lahti M. Mismatch repair defects in cancer. Cur. Opin. Genet. Dev. 10:2000;157-161
5. Bignami M., O'Driscoll M., Aquilina G., Karran P. Unmasking a killer: DNA O6-methyguanine and the cytotoxicity of methylating agents. Mutat. Res. 462:2000;71-82
6. Hanawalt P.C. Subpathways of nucleotide excision repair and their regulation. Oncogene. 21:2002;8949-8956
7. Lehmann A.R., Thompson A.F., Harcourt S.A., Stefanini M., Norris P.G. Cockayne's syndrome: correlation of clinical features with cellular sensitivity of RNA synthesis to UV irradiation. J. Med. Genet. 30:1993;569-682
8. Tang J., Chu G. Xeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein. DNA Repair. 1:2002;601-616
9. Mellon I., Champe G.N. Products of DNA mismatch repair genes mutS and mutL are required for transcription-coupled nucleotide-excision repair of the lactose operon in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 93:1996;1292-1297
10. Sweder K.S., Verhage R.A., Crowley D.J., Crouse G.F., Brouwer J., Hanawalt P.C. Mismatch repair mutants in yeast are not defective in transcription-coupled DNA repair of UV-induced DNA damage. Genetics. 143:1996;1127-1135
11. Mellon I., Rajpal D.K., Koi M., Boland C.R., Champe G.N. Transcription-coupled repair deficiency and mutations in human mismatch repair genes. Science. 272:1996;557-560
12. Leadon S.A., Avrutskaya A.V. Differential involvement of the human mismatch repair proteins. Cancer Res. 57:1997;3784-3791
13. Leadon S.A. Transcription-coupled repair of DNA damage: unanticipated players, unexpected complexities. Am. J. Hum. Genet. 64:1999;1259-1263
14. Leadon S.A., Avrutskaya A.V. Retraction. Cancer Res. 63:2003;3846
15. Cline S.D., Hanawalt P.C. Who's on first in the cellular response to DNA damage. Nat. Rev. Mol. Cell Biol. 4:2003;361-372
16. Sonneveld E., Vrieling H., Mullenders L.H.F., van Hoffen A. Mouse mismatch repair gene Msh2 is not essential for transcription-coupled repair of UV-induced cyclobutane pyrimidine dimers. Oncogene. 20:2001;538-541
17. Rochette P.J., Bastien N., McKay B.C., Therrien J.P., Dobretsky E.A., Drouin R. Human cells bearing homozygous mutations in the DNA mismatch repair genes hMLH1 or hMH2 are fully proficiennt in transcription-coupled nucleotide excision repair. Oncogene. 21:2002;5743-5752
18. Oda S., Humbert O., Fiumicino S., Bignami M., Karran P. Efficient repair of A/C mismatches in mouse cells deficient in long patch mismatch repair. EMBO J. 19:2000;1711-1718
19. Vreeswijk M.P., van Hoffen A., Westland B.E., Vrieling H., van Zeeland A.A., Mullenders L.H. Analysis of repair of cyclobutane pyrimidine dimers and pyrimidine 6-4 pyrimidone photoproducts in transcriptionally active and inactive genes in Chinese hamster cells. J. Biol. Chem. 269:1994;31858-31863
20. H.J. Ruven, C.M. Seelen, P.M. Lohman, L.H. Mullenders, A.A. van Zeeland, Efficient synthesis of 32P-labeled single-stranded DNA probes using linear PCR application of the method for analysis of strand-specific DNA repair, 1994.
21. Shivji M.K., Moggs J.G., Kuraoka I., Wood R.D. Dual-incision assays for nucleotide excision repair using DNA with a lesion at a specific site. Methods Mol. Biol. 113:1999;373-392
22. Macpherson P., Humbert O., Karran P. Frameshift mismatch recognition by the human MutSa complex. Mutat. Res. 408:1998;55-66
23. Zhen W., Link C.J., O'Connor P.M., Reed E., Parker R., Howell S.B., Bohr V.A. Increased gene-specific repair of cisplatin interstrand cross-links in cisplatin-resistant human ovarian cancer cell lines. Mol. Cell. Biol. 12:1992;3689-3698
24. Le Page F., Kwoh E.E., Avrutskaya A., Gentil A., Leadon S.A., Sarasin A., Cooper P.K. Transcription-coupled repair of 8-oxoguanine: requirement for XPG, TFIIH, and CSB and implications for Cockayne syndrome. Cell. 101:2000;159-171
25. Lettieri T., Marra G., Aquilina G., Bignami M., Palombo F., Jiricny J. Effect of hMSH6 cDNA expression on the phenotype of mismatch repair-deficient colon cancer cell line HCT15. Carcinogenesis. 20:1999;373-382
26. Claij N., te Riele H. Methylation tolerance in mismatch repair proficient cells with low MSH2 protein level. Oncogene. 21:2002;2873-2879
27. O'Driscoll M., Martinelli S., Ciotta C., Karran P. Combined mismatch and nucleotide excision repair defects in a human cell line: mismatch repair processes methylation but not UV- or ionizing-radiation-induced DNA damage. Carcinogenesis. 20:1999;799-804
28. Mu D., Tursun M., Duckett D.R., Drummond J.T., Modrich P., Sancar A. Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems. Mol. Cell. Biol. 17:1997;760-769
29. Meira L.B., Cheo D.L., Reis A.M., Claij N., Burns D.K., te Riele H., Friedberg E.C. Mice defective in the mismatch repair gene Msh2 show increased predisposition to UVB radiation-induced skin cancer. DNA Repair. 1:2002;929-934
30. Yoshino M., Nakatsu Y., te Riele H., Hirota S., Kitamura Y., Tanaka K. Additive roles of XPA and MSH2 genes in UVB-induced skin tumorigenesis in mice. DNA Repair. 1:2002;935-940
31. Nara K., Nagashima F., Yasui A. Highly elevated ultraviolet-induced mutation frequency in isolated Chinese hamster cell lines defective in nucleotide excision repair and mismatch repair proteins. Cancer Res. 61:2001;50-52