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Volumn 31, Issue 3, 2003, Pages 226-233

Hammerhead ribozyme-mediated cleavage of the fusion transcript NPM-ALK associated with anaplastic large-cell lymphoma

Author keywords

[No Author keywords available]

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; DNA; NUCLEOPLASMIN; RIBOZYME; RNA;

EID: 2342540711     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(02)01084-6     Document Type: Article
Times cited : (23)

References (41)
  • 1
    • 0028198206 scopus 로고
    • Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
    • Morris S.W., Kirstein M.N., Valentine M.B.et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science. 263:1994;1281-1284.
    • (1994) Science. , vol.263 , pp. 1281-1284
    • Morris, S.W.1    Kirstein, M.N.2    Valentine, M.B.3
  • 2
    • 8544278124 scopus 로고    scopus 로고
    • Long-range amplification of genomic DNA detects the t(2;5)(p23;q35) in anaplastic large-cell lymphoma, but not in other non-Hodgkin's lymphomas, Hodgkin's disease, or lymphomatoid papulosis
    • Sarris A.H., Luthra R., Papadimitracopoulou V.et al. Long-range amplification of genomic DNA detects the t(2;5)(p23;q35) in anaplastic large-cell lymphoma, but not in other non-Hodgkin's lymphomas, Hodgkin's disease, or lymphomatoid papulosis. Ann Oncol. 8(Suppl 2):1997;59-63.
    • (1997) Ann Oncol. , vol.8 , Issue.SUPPL. 2 , pp. 59-63
    • Sarris, A.H.1    Luthra, R.2    Papadimitracopoulou, V.3
  • 3
    • 0034554843 scopus 로고    scopus 로고
    • + anaplastic large cell lymphoma: A review of its histopathologic, genetic, and clinical features
    • + anaplastic large cell lymphoma. a review of its histopathologic, genetic, and clinical features Blood. 96:2000;3681-3695.
    • (2000) Blood. , vol.96 , pp. 3681-3695
    • Stein, H.1    Foss, H.D.2    Durkop, H.3
  • 4
    • 0035005624 scopus 로고    scopus 로고
    • + lymphomas: A distinct molecular genetic subtype of non-Hodgkin's lymphoma
    • + lymphomas. A distinct molecular genetic subtype of non-Hodgkin's lymphoma Br J Haematol. 113:2001;275-295.
    • (2001) Br J Haematol. , vol.113 , pp. 275-295
    • Morris, S.W.1    Xue, L.2    Ma, Z.3    Kinney, M.C.4
  • 5
    • 0030825594 scopus 로고    scopus 로고
    • Isolation and characterization of the human nucleophosmin/B23 (NPM) gene: Identification of the YY1 binding site at the 5′ enhancer region
    • Chan P.K., Chan F.Y., Morris S.W., Xie Z. Isolation and characterization of the human nucleophosmin/B23 (NPM) gene. identification of the YY1 binding site at the 5′ enhancer region Nucleic Acids Res. 25:1997;1225-1232.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 1225-1232
    • Chan, P.K.1    Chan, F.Y.2    Morris, S.W.3    Xie, Z.4
  • 6
    • 0031055562 scopus 로고    scopus 로고
    • Detection of anaplastic lymphoma kinase (ALK) and nucleolar protein nucleophosmin (NPM)-ALK proteins in normal and neoplastic cells with the monoclonal antibody ALK1
    • Pulford K., Lamant L., Morris S.W.et al. Detection of anaplastic lymphoma kinase (ALK) and nucleolar protein nucleophosmin (NPM)-ALK proteins in normal and neoplastic cells with the monoclonal antibody ALK1. Blood. 89:1997;1394-1404.
    • (1997) Blood. , vol.89 , pp. 1394-1404
    • Pulford, K.1    Lamant, L.2    Morris, S.W.3
  • 7
    • 0031008896 scopus 로고    scopus 로고
    • ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase
    • Morris S.W., Naeve C., Mathew P.et al. ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase. Oncogene. 14:1997;2175-2188.
    • (1997) Oncogene. , vol.14 , pp. 2175-2188
    • Morris, S.W.1    Naeve, C.2    Mathew, P.3
  • 8
    • 0030934862 scopus 로고    scopus 로고
    • Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis
    • Bischof D., Pulford K., Mason D.Y., Morris S.W. Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis. Mol Cell Biol. 17:1997;2312-2325.
    • (1997) Mol Cell Biol. , vol.17 , pp. 2312-2325
    • Bischof, D.1    Pulford, K.2    Mason, D.Y.3    Morris, S.W.4
  • 9
    • 0031755958 scopus 로고    scopus 로고
    • Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-γ to mediate its mitogenicity
    • Bai R.Y., Dieter P., Peschel C., Morris S.W., Duyster J. Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-γ to mediate its mitogenicity. Mol Cell Biol. 18:1998;6951-6961.
    • (1998) Mol Cell Biol. , vol.18 , pp. 6951-6961
    • Bai, R.Y.1    Dieter, P.2    Peschel, C.3    Morris, S.W.4    Duyster, J.5
  • 10
    • 0344822643 scopus 로고    scopus 로고
    • The tyrosine kinase NPM-ALK, associated with anaplastic large cell lymphoma, binds the intracellular domain of the surface receptor CD30 but is not activated by CD30 stimulation
    • Hübinger G., Scheffrahn I., Muller E.et al. The tyrosine kinase NPM-ALK, associated with anaplastic large cell lymphoma, binds the intracellular domain of the surface receptor CD30 but is not activated by CD30 stimulation. Exp Hematol. 27:1999;1796-1805.
    • (1999) Exp Hematol. , vol.27 , pp. 1796-1805
    • Hübinger, G.1    Scheffrahn, I.2    Muller, E.3
  • 11
    • 0035266314 scopus 로고    scopus 로고
    • Role of PI-3K-AKT pathway in NPM/ALK-mediated lymphomagenesis
    • Slupianek A., Nieborowska-Skorska M., Hoser G.et al. Role of PI-3K-AKT pathway in NPM/ALK-mediated lymphomagenesis. Cancer Res. 61:2001;2194-2199.
    • (2001) Cancer Res. , vol.61 , pp. 2194-2199
    • Slupianek, A.1    Nieborowska-Skorska, M.2    Hoser, G.3
  • 12
    • 0034672140 scopus 로고    scopus 로고
    • Nucleophosmin-anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway
    • Bai R.Y., Ouyang T., Miething C., Morris S.W., Peschel C., Duyster J. Nucleophosmin-anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway. Blood. 96:2000;4319-4327.
    • (2000) Blood. , vol.96 , pp. 4319-4327
    • Bai, R.Y.1    Ouyang, T.2    Miething, C.3    Morris, S.W.4    Peschel, C.5    Duyster, J.6
  • 13
    • 0030003813 scopus 로고    scopus 로고
    • Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5)
    • Fujimoto J., Shiota M., Iwahara T.et al. Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5). Proc Natl Acad Sci U S A. 93:1996;4181-4186.
    • (1996) Proc Natl Acad Sci U S A. , vol.93 , pp. 4181-4186
    • Fujimoto, J.1    Shiota, M.2    Iwahara, T.3
  • 14
    • 85047699293 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death
    • Zamo A., Chiarle R., Piva R.et al. 2002) Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death. Oncogene. 21:2002;1038-1047.
    • (2002) Oncogene. , vol.21 , pp. 1038-1047
    • Zamo, A.1    Chiarle, R.2    Piva, R.3
  • 15
    • 0033824668 scopus 로고    scopus 로고
    • Pathobiology of NPM-ALK and variant fusion genes in anaplastic large cell lymphoma and other lymphomas
    • Drexler H.G., Gignac S.M., von Wasielewski R., Werner M., Dirks W.G. Pathobiology of NPM-ALK and variant fusion genes in anaplastic large cell lymphoma and other lymphomas. Leukemia. 14:2000;1533-1559.
    • (2000) Leukemia. , vol.14 , pp. 1533-1559
    • Drexler, H.G.1    Gignac, S.M.2    Von Wasielewski, R.3    Werner, M.4    Dirks, W.G.5
  • 16
    • 0034045628 scopus 로고    scopus 로고
    • ALK expression in extranodal anaplastic large cell lymphoma favors systemic disease with (primary) nodal involvement and a good prognosis and occurs before dissemination
    • ten Berge R.L., Oudejans J.J., Ossenkoppele G.J.et al. ALK expression in extranodal anaplastic large cell lymphoma favors systemic disease with (primary) nodal involvement and a good prognosis and occurs before dissemination. J Clin Pathol. 53:2000;445-450.
    • (2000) J Clin Pathol. , vol.53 , pp. 445-450
    • Ten Berge, R.L.1    Oudejans, J.J.2    Ossenkoppele, G.J.3
  • 17
    • 0033151520 scopus 로고    scopus 로고
    • Prognostic significance of anaplastic lymphoma kinase (ALK) protein expression in adults with anaplastic large cell lymphoma
    • Gascoyne R.D., Aoun P., Wu D.et al. Prognostic significance of anaplastic lymphoma kinase (ALK) protein expression in adults with anaplastic large cell lymphoma. Blood. 93:1999;3913-3921.
    • (1999) Blood. , vol.93 , pp. 3913-3921
    • Gascoyne, R.D.1    Aoun, P.2    Wu, D.3
  • 18
    • 17344388062 scopus 로고    scopus 로고
    • Cellular kinetic differences between Hodgkin's and anaplastic large cell lymphomas: Relation to the expression of p34cdc2 and cyclin B-1
    • Leoncini L., Megha T., Lazzi S.et al. Cellular kinetic differences between Hodgkin's and anaplastic large cell lymphomas. relation to the expression of p34cdc2 and cyclin B-1 Int J Cancer. 77:1998;408-414.
    • (1998) Int J Cancer. , vol.77 , pp. 408-414
    • Leoncini, L.1    Megha, T.2    Lazzi, S.3
  • 19
    • 0030809095 scopus 로고    scopus 로고
    • Retrovirus-mediated gene transfer of NPM-ALK causes lymphoid malignancy in mice
    • Kuefer M.U., Look A.T., Pulford K.et al. Retrovirus-mediated gene transfer of NPM-ALK causes lymphoid malignancy in mice. Blood. 90:1997;2901-2910.
    • (1997) Blood. , vol.90 , pp. 2901-2910
    • Kuefer, M.U.1    Look, A.T.2    Pulford, K.3
  • 20
    • 0019856947 scopus 로고
    • In vitro splicing of the ribosomal RNA precursor of Tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence
    • Cech T.R., Zaug A.J., Grabowski P.J. In vitro splicing of the ribosomal RNA precursor of Tetrahymena. involvement of a guanosine nucleotide in the excision of the intervening sequence Cell. 27:1981;487-496.
    • (1981) Cell. , vol.27 , pp. 487-496
    • Cech, T.R.1    Zaug, A.J.2    Grabowski, P.J.3
  • 21
    • 0023221419 scopus 로고
    • A small catalytic oligoribonucleotide
    • Uhlenbeck O.C. A small catalytic oligoribonucleotide. Nature. 328:1987;596-600.
    • (1987) Nature. , vol.328 , pp. 596-600
    • Uhlenbeck, O.C.1
  • 22
    • 0028939524 scopus 로고
    • Multi-unit ribozyme-mediated cleavage of bcr-abl mRNA in myeloid leukemias
    • Leopold L.H., Shore S.K., Newkirk T.A., Reddy R.M., Reddy E.P. Multi-unit ribozyme-mediated cleavage of bcr-abl mRNA in myeloid leukemias. Blood. 85:1995;2162-2170.
    • (1995) Blood. , vol.85 , pp. 2162-2170
    • Leopold, L.H.1    Shore, S.K.2    Newkirk, T.A.3    Reddy, R.M.4    Reddy, E.P.5
  • 23
    • 0031601758 scopus 로고    scopus 로고
    • Selection of a high activity c-erbB-2 ribozyme using a fusion gene of c-erbB-2 and the enhanced green fluorescent protein
    • Wiechen K., Zimmer C., Dietel M. Selection of a high activity c-erbB-2 ribozyme using a fusion gene of c-erbB-2 and the enhanced green fluorescent protein. Cancer Gene Ther. 5:1998;45-51.
    • (1998) Cancer Gene Ther. , vol.5 , pp. 45-51
    • Wiechen, K.1    Zimmer, C.2    Dietel, M.3
  • 24
    • 0034128434 scopus 로고    scopus 로고
    • Anti-K-ras ribozyme induces growth inhibition and increased chemosensitivity in human colon cancer cells
    • Funato T., Ishii T., Kambe M., Scanlon K.J., Sasaki T. Anti-K-ras ribozyme induces growth inhibition and increased chemosensitivity in human colon cancer cells. Cancer Gene Ther. 7:2000;495-500.
    • (2000) Cancer Gene Ther. , vol.7 , pp. 495-500
    • Funato, T.1    Ishii, T.2    Kambe, M.3    Scanlon, K.J.4    Sasaki, T.5
  • 25
    • 0034117829 scopus 로고    scopus 로고
    • Inhibition of cell proliferation in HCC-9204 hepatoma cells by a c-myc-specific ribozyme
    • Cheng J., Luo J., Zhang X.et al. Inhibition of cell proliferation in HCC-9204 hepatoma cells by a c-myc-specific ribozyme. Cancer Gene Ther. 7:2000;407-412.
    • (2000) Cancer Gene Ther. , vol.7 , pp. 407-412
    • Cheng, J.1    Luo, J.2    Zhang, X.3
  • 26
    • 0036654205 scopus 로고    scopus 로고
    • Ribozyme-mediated suppression of vascular endothelial growth factor gene expression enhances matrix metalloproteinase 1 expression in a human hepatocellular carcinoma cell line
    • Kamochi J., Tokunaga T., Morino F.et al. Ribozyme-mediated suppression of vascular endothelial growth factor gene expression enhances matrix metalloproteinase 1 expression in a human hepatocellular carcinoma cell line. Int J Oncol. 21:2002;81-84.
    • (2002) Int J Oncol. , vol.21 , pp. 81-84
    • Kamochi, J.1    Tokunaga, T.2    Morino, F.3
  • 28
    • 0035252939 scopus 로고    scopus 로고
    • cip1/ waf1 in the anaplastic large cell lymphoma cell line Karpas 299
    • cip1/ waf1 in the anaplastic large cell lymphoma cell line Karpas 299. Oncogene. 20:2001;590-598.
    • (2001) Oncogene. , vol.20 , pp. 590-598
    • Hübinger Müller, E.1    Scheffrahn, I.2
  • 29
    • 0030939002 scopus 로고    scopus 로고
    • The structure, function and application of the hammerhead ribozyme
    • Birikh K.R., Heaton P.A., Eckstein F. The structure, function and application of the hammerhead ribozyme. Eur J Biochem. 245:1997;1-16.
    • (1997) Eur J Biochem. , vol.245 , pp. 1-16
    • Birikh, K.R.1    Heaton, P.A.2    Eckstein, F.3
  • 30
    • 0031973036 scopus 로고    scopus 로고
    • The therapeutic potential of ribozymes
    • James H.A., Gibson I. The therapeutic potential of ribozymes. Blood. 91:1998;371-382.
    • (1998) Blood. , vol.91 , pp. 371-382
    • James, H.A.1    Gibson, I.2
  • 31
    • 0034730321 scopus 로고    scopus 로고
    • Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication
    • Okuda M., Horn H.F., Tarapore P.et al. Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication. Cell. 103:2000;127-140.
    • (2000) Cell. , vol.103 , pp. 127-140
    • Okuda, M.1    Horn, H.F.2    Tarapore, P.3
  • 32
    • 0033561433 scopus 로고    scopus 로고
    • + lymphoma: Clinico-pathological findings and outcome
    • + lymphoma. Clinico-pathological findings and outcome Blood. 93:1999;2697-2706.
    • (1999) Blood. , vol.93 , pp. 2697-2706
    • Falini, B.1    Pileri, S.2    Zinzani, P.L.3
  • 33
    • 0344850198 scopus 로고    scopus 로고
    • TRK-fused gene (TFG) is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocations
    • Hernandez L., Pinyol M., Hernandez S.et al. TRK-fused gene (TFG) is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocations. Blood. 94:1999;3265-3268.
    • (1999) Blood. , vol.94 , pp. 3265-3268
    • Hernandez, L.1    Pinyol, M.2    Hernandez, S.3
  • 34
    • 0033890820 scopus 로고    scopus 로고
    • TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors
    • Lawrence B., Perez-Atayde A., Hibbard M.K.et al. TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors. Am J Pathol. 157:2000;377-384.
    • (2000) Am J Pathol. , vol.157 , pp. 377-384
    • Lawrence, B.1    Perez-Atayde, A.2    Hibbard, M.K.3
  • 35
    • 0033899383 scopus 로고    scopus 로고
    • Atic-alk: A novel variant alk gene fusion in anaplastic large cell lymphoma resulting from the recurrent cryptic chromosomal inversion, inv(2)(p23q35)
    • Colleoni G.W., Bridge J.A., Garicochea B., Liu J., Filippa D.A., Ladanyi M. Atic-alk. A novel variant alk gene fusion in anaplastic large cell lymphoma resulting from the recurrent cryptic chromosomal inversion, inv(2)(p23q35) Am J Pathol. 156:2000;781-789.
    • (2000) Am J Pathol. , vol.156 , pp. 781-789
    • Colleoni, G.W.1    Bridge, J.A.2    Garicochea, B.3    Liu, J.4    Filippa, D.A.5    Ladanyi, M.6
  • 36
    • 0034653984 scopus 로고    scopus 로고
    • Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to ATIC, an enzyme involved in purine nucleotide biosynthesis
    • Ma Z., Cools J., Marynen P.et al. Inv(2)(p23q35) in anaplastic large-cell lymphoma induces constitutive anaplastic lymphoma kinase (ALK) tyrosine kinase activation by fusion to ATIC, an enzyme involved in purine nucleotide biosynthesis. Blood. 95:2000;2144-2149.
    • (2000) Blood. , vol.95 , pp. 2144-2149
    • Ma, Z.1    Cools, J.2    Marynen, P.3
  • 38
    • 0034658434 scopus 로고    scopus 로고
    • + lymphoma: 2 cases expressing ALK kinase fused to CLTCL (clathrin chain polypeptide-like)
    • + lymphoma. 2 cases expressing ALK kinase fused to CLTCL (clathrin chain polypeptide-like) Blood. 95:2000;3204-3207.
    • (2000) Blood. , vol.95 , pp. 3204-3207
    • Touriol, C.1    Greenland, C.2    Lamant, L.3
  • 39
    • 13044279495 scopus 로고    scopus 로고
    • The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1α
    • Salgia R., Quackenbush E., Lin J.et al. The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1α Blood. 94:1999;4233-4246.
    • (1999) Blood. , vol.94 , pp. 4233-4246
    • Salgia, R.1    Quackenbush, E.2    Lin, J.3
  • 40
    • 0025038410 scopus 로고
    • BCR-ABL and BCR proteins: Biochemical characterization and localization
    • Dhut S., Chaplin T., Young B.D. BCR-ABL and BCR proteins. biochemical characterization and localization Leukemia. 4:1990;745-750.
    • (1990) Leukemia. , vol.4 , pp. 745-750
    • Dhut, S.1    Chaplin, T.2    Young, B.D.3
  • 41
    • 0031715435 scopus 로고    scopus 로고
    • The influence of target protein half-life on the effectiveness of antisense oligonucleotide analog-mediated biologic responses
    • Spiller D.G., Giles R.V., Broughton C.M.et al. The influence of target protein half-life on the effectiveness of antisense oligonucleotide analog-mediated biologic responses. Antisense Nucleic Acid Drug Dev. 8:1998;281-293.
    • (1998) Antisense Nucleic Acid Drug Dev. , vol.8 , pp. 281-293
    • Spiller, D.G.1    Giles, R.V.2    Broughton, C.M.3


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