The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1α

Blood

Volumn 94, Issue 12, 1999, Pages 4233-4246

  Salgia, Ravi ^a   Quackenbush, Elizabeth ^b   Lin, Jeffrey ^b   Souchkova, Natalia ^b   Sattler, Martin ^b   Ewaniuk, Darren S ^b   Klucher, Kevin M ^b   Daley, George Q ^b   Kraeft, Stine K ^b   Sackstein, Robert ^b   Alyea III, Edwin P ^b   Von Andrian, Ulrich H ^b   Chen, Lan Bo ^b   Gutierrez Ramos, Jose Carlos ^b   Pendergast, Ann Marie ^b   Griffin, James D ^b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CXCR4; STROMAL CELL DERIVED FACTOR 1ALPHA; TETRACYCLINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CALCIUM TRANSPORT; CELL TRANSFORMATION; CHEMOTAXIS; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; HEMATOPOIESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; INHIBITION KINETICS; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROTEIN INDUCTION; RECEPTOR BINDING;

ANIMALS; ANTI-HIV AGENTS; CELL TRANSFORMATION, NEOPLASTIC; CHEMOKINES, CXC; CHEMOTAXIS; FUSION PROTEINS, BCR-ABL; GENE EXPRESSION REGULATION, NEOPLASTIC; HEMATOPOIETIC STEM CELLS; HUMANS; MICE;

EID: 13044279495     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Sattler M, Salgia R: Dysregulation of hematopoietic growth factor signal transduction by the oncogene BCR/ABL. Cytokine Growth Factor Rev 8:63, 1997
2. Gordon MY, Dowding CR, Riley GP, Goldman JM, Greaves MF: Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia. Nature 328:342, 1987
3. Verfaillie CM, McCarthy JB, McGlave PB: Mechanisms underlying abnormal trafficking of malignant progenitors in chronic myelogenous leukemia. J Clin Invest 90:1232, 1992
4. Bhatia R, McCarthy J, Verfaillie C: Interferon-α restores normal β1 integrin-mediated inhibition of hematopoietic progenitor proliferation by the marrow microenvironment in chronic myelogenous leukemia. Blood 87:3883, 1996
5. Salgia R, Brunkhorst B, Pisick E, Li J-L, Lo SH, Chen LB, Griffin JD: Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL. Oncogene 11:1149, 1995
6. Salgia R, Uemura N, Okuda K, Li J-L, Pisick E, Sattler M, deJong R, Druker B, Heisterkamp N, Chen L, Groffen J, Griffin J: CRKL links p210BCR/ABL with paxillin in chronic myelogenous leukemia cells. J Biol Chem 270:29145, 1995
7. Salgia R, Li J-L, Ewaniuk D, Pear W, Pisick E, Burky S, Ernst T, Sattler M, Chen L, Griffin J: BCR/ABL induces multiple abnormalities of cytoskeletal function. J Clin Invest 100:46, 1997
8. Aiuti A, Webb IJ, Bleul C, Springer T, Gutierrez-Ramos JC: The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood. J Exp Med 185:111, 1997
9. Nagasawa T, Nakajima T, Tachibana K, Iizasa H, Bleul CC, Yoshie O, Matsushima K, Yoshida N, Springer TA, Kishimoto T: Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin. Proc Natl Acad Sci USA 93:14726, 1996
10. Kim CH, Broxmeyer HE: In vitro behavior of hematopoietic progenitor cells under the influence of chemoattractants: Stromal derived factor-1, steel factor, and the bone marrow enviroment. Blood 91:100, 1998
11. Nagasawa T, Hirota S, Tachibana K, Takakura N, Nishikawa S, Kitamura Y, Yoshida N, Kikutani H, Kishimoto T: Defects of b-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the cxc chemokine pbsf/sdf-1. Nature 382:635, 1996
12. Tachibana K, Hirota S, Iizasa H, Yoshida H, Kawabata K, Kataoka Y, Kitamura Y, Matsushima K, Yoshida N, Nishikawa S, Kishimoto T, Nagasawa T: The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature 393:591, 1998
13. Zou YR, Kottmann AH, Kuroda M, Taniuchi I, Littman DR: Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 393:595, 1998
14. Matulonis U, Salgia R, Okuda K, Druker B, Griffin J: Interleukin-3 and p210 BCR/ABL activate both unique and overlapping pathways of signal transduction in a factor-dependent myeloid cell line. Exp Hematol 21:1460, 1993
15. Klucher K, Lopez D, Daley G: Secondary mutation maintains the transformed state in BaF3 cells with inducible BCR/ABL expression. Blood 91:3927, 1998
16. Bazzoni G, Carlesso N, Griffin J, Hemler M: BCR/ABL expression stimulates integrin function in hematopoietic cell lines. J Clin Invest 98:521, 1996
17. Salgia R, Li J, Lo SH, Brunkhorst B, Kansas GS, Sobhany ES, Sun YP, Pisick E, Hallek M, Ernst T, Tantravahi R, Chen LB, Griffin JD: Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by p210(bcr/abl). J Biol Chem 270:5039, 1995
18. Quackenbush E, Wershil B, Aguirre V, Gutierrez-Ramos J-C: Eotaxin modulates myelopoiesis and mast cell development from embryonic hematopoietic progenitors. Blood 92:1, 1998
19. Stockton B, Cheng G, Manjunath N, Ardman B, von Andrian U: Negative regulation of T cell homing by CD43. Immunity 8:373, 1998
20. Chissoe SL, Bodenteich A, Wang YF, Wang YP, Burian D, Clifton SW, Crabtree J, Freeman A, Iyer K, Li JA, Ma YC, Mclaury HJ, Pan HQ, Sarhan OH, Toth S, Wang ZL, Zhang GZ, Heisterkamp N, Groffen J, Roe BA: Sequence and analysis of the human ab1 gene, the bcr gene, and regions involved in the Philadelphia chromosomal translocation. Genomics 27:67, 1995
21. Galbraith P, Abu-Zahra H: Granulopoiesis in chronic granulocytic leukaemia. Br J Hematol 22:135, 1972
22. Baggiolini M: Chemokines and leukocyte traffic. Nature 392: 565, 1998
23. Cramer E, Auclair C, Hakim J: Metabolic activity of phagocytosis granulocytes in chronic granulocytic leukemia. Blood 50:93, 1977
24. Eaves C, Cashman J, Wolpe S, Eaves A: Unresponsiveness of primitive chronic myeloid leukemia cells to macrophage inflammatory protein 1 alpha, an inhibitor of primitive normal hematopoietic cells. Proc Natl Acad Sci USA 90:12015, 1993
25. Wark G, Heyworth C, Spooncer E, Czaplewski L, Francis J, Dexter T, Whetton A: Ab1 protein kinase abrogates the response of multipotent haemopoietic cells to the growth inhibitor macrophage inflammatory protein-1 alpha. Oncogene 16:1319, 1998
26. Lapidot T, Peled A, Petit I, Kollet O, Magid M, Ponomaryov T, Franitza S, Grabovsky V, Nagler A, Lider O, Alon R: Ex-vivo expansion of migrating human CXCR4+-SCID repopulating cells by upregulation of surface CXCR-4 expression in response to stimulation with SCF or IL-6. Blood 92:717a, 1998 (abstr, suppl 1)
27. Lapidot T, Peled A, Petit I, Kollet O, Magid M, Ponomaryov T, Franitza S, Grabovsky V, Nagler A, Lider R, Alon R, Zipori D: The chemokine SDF-1a and the cytokine SCF mediate CXCR-4 dependent homing of human CD34+/CD38- stem cells to the bone marrow of nod/scid mice. Blood 92:504a, 1998 (abstr, suppl 1)
28. Ma Q, Jones D, Springer T: The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment. Immunity 10:1, 1999
29. Cannistra S: Chronic myelogenous leukemia as a model for the genetic basis of cancer. Hematol Oncol Clin North Am 4:337, 1990
30. Bleul CC, Fuhlbrigge RC, Casasnovas JM, Aiuti A, Springer TA: A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). J Exp Med 184:1101, 1996
31. Luster AD: Chemokines-Chemotactic cytokines that mediate inflammation. N Engl J Med 338:436, 1998