-
1
-
-
0010646449
-
Synthesis and in vivo antimalarial activity of 12α-trifluoromethyl-hydroartemisinin
-
Abouabdellah, A., Bégué, J. P., Bonnet-Delpon, D., Gantier, J. C., Truong Thi Thanh, N. & Truong Dinh, T. (1996). Synthesis and in vivo antimalarial activity of 12α-trifluoromethyl-hydroartemisinin. Bioorganic and Medicinal Chemistry Letters, 6, 2717-2720.
-
(1996)
Bioorganic and Medicinal Chemistry Letters
, vol.6
, pp. 2717-2720
-
-
Abouabdellah, A.1
Bégué, J.P.2
Bonnet-Delpon, D.3
Gantier, J.C.4
Truong Thi Thanh, N.5
Truong Dinh, T.6
-
2
-
-
0031959993
-
Artemisinin pharmacokinetics in healthy adults after 250, 500 and 1000 mg single oral doses
-
Ashton, M., Toufigh Gordi, Trinh Ngoc Hai, Nguyen Van Huong, Nguyen Duy Sy, Nguyen Thi Nieu, Dinh Xuan Huong, Johansson, M. & Le Dinh Cong (1998a). Artemisinin pharmacokinetics in healthy adults after 250, 500 and 1000 mg single oral doses. Biopharmaceutics and Drug Disposition, 19, 245-250.
-
(1998)
Biopharmaceutics and Drug Disposition
, vol.19
, pp. 245-250
-
-
Ashton, M.1
Gordi, T.2
Ngoc Hai, T.3
Van Huong, N.4
Duy Sy, N.5
Thi Nieu, N.6
Xuan Huong, D.7
Johansson, M.8
Cong, L.D.9
-
3
-
-
0345628028
-
Artemisinin pharmacokinetics is time-dependent during repeated oral administration in healthy male adults
-
Ashton, M., Trinh Ngoc Hai, Nguyen Duy Sy, Dinh Xuan Huong, Nguyen Van Huong, Nguyen Thi Nieu & Le Dinh Cong (1998b). Artemisinin pharmacokinetics is time-dependent during repeated oral administration in healthy male adults. Drug Metabolism and Disposition, 26, 25-27.
-
(1998)
Drug Metabolism and Disposition
, vol.26
, pp. 25-27
-
-
Ashton, M.1
Ngoc Hai, T.2
Duy Sy, N.3
Xuan Huong, D.4
Van Huong, N.5
Thi Nieu, N.6
Cong, L.D.7
-
4
-
-
0028271047
-
In-vitro reversal of chloroquine resistance with chlorpheniramine against African isolates of Plasmodium falciparum
-
Basco, L. K. & Le Bras, J. (1994). In-vitro reversal of chloroquine resistance with chlorpheniramine against African isolates of Plasmodium falciparum. Japanese Journal of Medical Science and Biology, 47, 59-63.
-
(1994)
Japanese Journal of Medical Science and Biology
, vol.47
, pp. 59-63
-
-
Basco, L.K.1
Le Bras, J.2
-
5
-
-
0004071134
-
Molécules antipaludiques
-
Paris: Masson Publishers
-
Basco, L. K., Ruggeri, C. & Le Bras, J. (1994). Molécules antipaludiques. Me'anisme de résistance, volume 2. Paris: Masson Publishers, pp. 74-75.
-
(1994)
Me'anisme De Résistance
, vol.2
, pp. 74-75
-
-
Basco, L.K.1
Ruggeri, C.2
Le Bras, J.3
-
6
-
-
0025963466
-
Preparation of trifluoromethyl ketones and related fluorinated ketones
-
Bégué, J. P. & Bonnet-Delpon, D. (1991). Preparation of trifluoromethyl ketones and related fluorinated ketones. Tetrahedron, 47, 3207-3254.
-
(1991)
Tetrahedron
, vol.47
, pp. 3207-3254
-
-
Bégué, J.P.1
Bonnet-Delpon, D.2
-
8
-
-
0344639143
-
Detection of a system of microsomal monooxygenases in a malaria parasite of rodents, Plasmodium berghei
-
Chekhonadskikh, T. V., Polyakova, N. E., Pankova, T. G. & Salganik, R. I. (1987). Detection of a system of microsomal monooxygenases in a malaria parasite of rodents, Plasmodium berghei. Biochemistry-Moscow, 52, 327-331.
-
(1987)
Biochemistry-Moscow
, vol.52
, pp. 327-331
-
-
Chekhonadskikh, T.V.1
Polyakova, N.E.2
Pankova, T.G.3
Salganik, R.I.4
-
9
-
-
0026239217
-
Identification of the in vivo metabolites of the antimalarial arteether by thermospray high performance liquid chromatography/mass spectrometry
-
Chi, H. T., Ramu, K., Barker, J. K., Hufford, C. D., Lee, I. S., Zeng, Y. L. & McChesney, J. D. (1991). Identification of the in vivo metabolites of the antimalarial arteether by thermospray high performance liquid chromatography/mass spectrometry. Biological Mass Spectrometry, 20, 609-628.
-
(1991)
Biological Mass Spectrometry
, vol.20
, pp. 609-628
-
-
Chi, H.T.1
Ramu, K.2
Barker, J.K.3
Hufford, C.D.4
Lee, I.S.5
Zeng, Y.L.6
McChesney, J.D.7
-
10
-
-
0020097276
-
Studies on the toxicity of quinghaosu and its derivatives
-
China Cooperative Research Group on Qinghaosu and its Derivatives as Antimalarials
-
China Cooperative Research Group on Qinghaosu and its Derivatives as Antimalarials (1982a). Studies on the toxicity of quinghaosu and its derivatives. Journal of Traditional Chinese Medicine, 2, 31-38.
-
(1982)
Journal of Traditional Chinese Medicine
, vol.2
, pp. 31-38
-
-
-
11
-
-
0020097272
-
Clinical studies on the treatment of malaria with quinghaosu and its derivatives
-
China Cooperative Research Group on Qinghaosu and its Derivatives as Antimalarials
-
China Cooperative Research Group on Qinghaosu and its Derivatives as Antimalarials (1982b). Clinical studies on the treatment of malaria with quinghaosu and its derivatives. Journal of Traditional Chinese Medicine, 2, 45-50.
-
(1982)
Journal of Traditional Chinese Medicine
, vol.2
, pp. 45-50
-
-
-
12
-
-
0019174245
-
Activities of 25 derivatives of artemisinine against chloroquine-resistant Plasmodium berghei
-
Gu, H. M., Lu, B. F. & Qu, Z. X. (1980). Activities of 25 derivatives of artemisinine against chloroquine-resistant Plasmodium berghei. Acta Pharmacological Sinica, 1, 48-50.
-
(1980)
Acta Pharmacological Sinica
, vol.1
, pp. 48-50
-
-
Gu, H.M.1
Lu, B.F.2
Qu, Z.X.3
-
13
-
-
85031227378
-
Study on the toxicology of natri artesunate and its effect to the other drugs metabolism in experimental animals
-
PhD thesis, Hanoi Medical University, Viet Nam
-
Huong, N. T. G. (1997). Study on the toxicology of natri artesunate and its effect to the other drugs metabolism in experimental animals. PhD thesis, Hanoi Medical University, Viet Nam.
-
(1997)
-
-
Huong, N.T.G.1
-
14
-
-
0028068979
-
Comparison of in vivo and in vitro antimalarial activity of artemisinin, dihydroartemisinin and sodium artesunate in the Plasmodium berghei-rodent model
-
Janse, C. J., Waters, A. P., Kos, J. & Lugt, C. B. (1994). Comparison of in vivo and in vitro antimalarial activity of artemisinin, dihydroartemisinin and sodium artesunate in the Plasmodium berghei-rodent model. International Journal for Parasitology, 24, 589-594.
-
(1994)
International Journal for Parasitology
, vol.24
, pp. 589-594
-
-
Janse, C.J.1
Waters, A.P.2
Kos, J.3
Lugt, C.B.4
-
15
-
-
0029044399
-
Mechanism-based development of new antimalarials: Synthesis of derivatives of artemisinin attached to iron chelators
-
Kamchonwongpaisan, S., Paitayatat, S., Thebtaranonth, Y., Wilairat, P. & Yuthavong, Y. (1995). Mechanism-based development of new antimalarials: synthesis of derivatives of artemisinin attached to iron chelators. Journal of Medicinal Chemistry, 38, 2311-2316.
-
(1995)
Journal of Medicinal Chemistry
, vol.38
, pp. 2311-2316
-
-
Kamchonwongpaisan, S.1
Paitayatat, S.2
Thebtaranonth, Y.3
Wilairat, P.4
Yuthavong, Y.5
-
16
-
-
0021948029
-
Qinghaosu (artemisinin): An antimalarial drug from China
-
Klayman, D. L. (1985). Qinghaosu (artemisinin): an antimalarial drug from China. Science, 288, 1049-1055.
-
(1985)
Science
, vol.288
, pp. 1049-1055
-
-
Klayman, D.L.1
-
17
-
-
0025835250
-
Hepatic metabolism of artemisinin drugs: I. Drug metabolism in rat liver microsomes
-
Leskovac, V. & Theoharides, A. D. (1991). Hepatic metabolism of artemisinin drugs: I. Drug metabolism in rat liver microsomes. Comparative Biochemistry and Physiology C - Pharmacology, Toxicology and Endocrinology, 99C, 383-396.
-
(1991)
Comparative Biochemistry and Physiology C - Pharmacology, Toxicology and Endocrinology,
, vol.99 C
, pp. 383-396
-
-
Leskovac, V.1
Theoharides, A.D.2
-
18
-
-
0028951562
-
Antimalarial activity of new dihydroartemisinin derivatives. 6. α-Alkylbenzylic ethers
-
Lin, A. J. & Miller, R. E. (1995). Antimalarial activity of new dihydroartemisinin derivatives. 6. α-Alkylbenzylic ethers. Journal of Medicinal Chemistry, 38, 764-770.
-
(1995)
Journal of Medicinal Chemistry
, vol.38
, pp. 764-770
-
-
Lin, A.J.1
Miller, R.E.2
-
19
-
-
0030963326
-
Antimalarial activity of new hydro artemisinin derivatives. 7.4-(p-substituted phenyl)- 4 (R or S)- [10(α or β) dihydroartemisinin oxy] butyric acids
-
Lin, A. J., Zikry, A. B. & Kyle. D. E. (1997). Antimalarial activity of new hydro artemisinin derivatives. 7.4-(p-substituted phenyl)- 4 (R or S)- [10(α or β) dihydroartemisinin oxy] butyric acids. Journal of Medicinal Chemistry, 40, 1396-1400.
-
(1997)
Journal of Medicinal Chemistry
, vol.40
, pp. 1396-1400
-
-
Lin, A.J.1
Zikry, A.B.2
Kyle, D.E.3
-
20
-
-
0023110445
-
The chemistry, pharmacology, and clinical applications of qinghaosu (artemisinin) and its derivatives
-
Luo, X. D. & Shen, C. C. (1987). The chemistry, pharmacology, and clinical applications of qinghaosu (artemisinin) and its derivatives. Medicinal Research Review, 7, 29-52.
-
(1987)
Medicinal Research Review
, vol.7
, pp. 29-52
-
-
Luo, X.D.1
Shen, C.C.2
-
21
-
-
0026775845
-
A new potent enkephalin analog containing trifluoromethyl-amino acid residues
-
Ojima, I., Kato, K., Jameison, F. A., Conway, J., Nakahashi, K., Hagiwara, M., Miyamae, T. & Radunz, H. E. (1992). A new potent enkephalin analog containing trifluoromethyl-amino acid residues. Bioorganic and Medicinal Chemistry Letters, 2, 219-222.
-
(1992)
Bioorganic and Medicinal Chemistry Letters
, vol.2
, pp. 219-222
-
-
Ojima, I.1
Kato, K.2
Jameison, F.A.3
Conway, J.4
Nakahashi, K.5
Hagiwara, M.6
Miyamae, T.7
Radunz, H.E.8
-
22
-
-
0344207602
-
Techniques of drug evaluation I: Primary screening
-
Peters, W. (editor). London: Academic Press
-
Peters, W. (1987). Techniques of drug evaluation I: primary screening. In: Chemotherapy and Drug Resistance in Malaria, volume 1, Peters, W. (editor). London: Academic Press, pp. 100-123.
-
(1987)
Chemotherapy and Drug Resistance in Malaria
, vol.1
, pp. 100-123
-
-
Peters, W.1
-
23
-
-
0028788118
-
Synthesis and antimalarial activities of several fluorinated artemisinin derivatives
-
Pu, Y. M., Torok, D. S., Ziffer, H., Pan, X. Q. & Meshnick, S. R. (1995). Synthesis and antimalarial activities of several fluorinated artemisinin derivatives. Journal of Medicinal Chemistry, 38, 4120-4124.
-
(1995)
Journal of Medicinal Chemistry
, vol.38
, pp. 4120-4124
-
-
Pu, Y.M.1
Torok, D.S.2
Ziffer, H.3
Pan, X.Q.4
Meshnick, S.R.5
-
24
-
-
0029071407
-
Synthesis, characterization, and antimalarial activity of the glucuronides of the hydroxylated metabolites of arteether
-
Ramu, K. & Baker, J. K. (1995). Synthesis, characterization, and antimalarial activity of the glucuronides of the hydroxylated metabolites of arteether. Journal of Medicinal Chemistry, 38, 1911-1921.
-
(1995)
Journal of Medicinal Chemistry
, vol.38
, pp. 1911-1921
-
-
Ramu, K.1
Baker, J.K.2
-
25
-
-
0024851248
-
Studies of qinghaosu and its active derivatives in biological materials and their pharmacokineties
-
Peking Union Medical College
-
Song, Z. Y. & Zhao, K. C. (1989). Studies of qinghaosu and its active derivatives in biological materials and their pharmacokineties. Proceedings of the Chinese Academy of Medicinal Science, Peking Union Medical College, 4, 229-234.
-
(1989)
Proceedings of the Chinese Academy of Medicinal Science
, vol.4
, pp. 229-234
-
-
Song, Z.Y.1
Zhao, K.C.2
-
26
-
-
13144307057
-
Artemisinin induces omeprazole metabolism in human beings
-
Svensson, U. S. H., Ashton, M., Hai, T. N., Bertilsson, L., Huong, D. X., Huong, N. V., Nieu, N. T., Sy, N. D., Lykkesfeldt, J. & Cong, L. D. (1998). Artemisinin induces omeprazole metabolism in human beings. Clinical Pharmacology and Therapeutics, 64, 160-167.
-
(1998)
Clinical Pharmacology and Therapeutics
, vol.64
, pp. 160-167
-
-
Svensson, U.S.H.1
Ashton, M.2
Hai, T.N.3
Bertilsson, L.4
Huong, D.X.5
Huong, N.V.6
Nieu, N.T.7
Sy, N.D.8
Lykkesfeldt, J.9
Cong, L.D.10
-
27
-
-
0032497703
-
Synthesis and antimalarial activities of fluoroalkyl derivatives of dihydroartemisinin
-
Thanh Nga, T. T., Ménage, C., Bégué, J. P., Bonnet-Delpon, D., Gantier, J. C., Pradines, B., Doury, J. C. & Thac, T. D. (1998). Synthesis and antimalarial activities of fluoroalkyl derivatives of dihydroartemisinin. Journal of Medicinal Chemistry, 41, 4101-4108.
-
(1998)
Journal of Medicinal Chemistry
, vol.41
, pp. 4101-4108
-
-
Thanh Nga, T.T.1
Ménage, C.2
Bégué, J.P.3
Bonnet-Delpon, D.4
Gantier, J.C.5
Pradines, B.6
Doury, J.C.7
Thac, T.D.8
-
28
-
-
85031213208
-
Estimate the effect of dihydroartemisinin (the produce of Vietnam) in mice infected with a P. berghei experimental model
-
Hanoi: National Institute of Malariology, Parasitology and Entomology, internal document, no. 4
-
Tien, N. T., Lien, L. K., Cong, L. D. Nhan, D. H., Huong, N. M., Hanh, N. T., Xuan, D. T., Tao, N. D. & Ha, N. T. H. (2000). Estimate the effect of dihydroartemisinin (the produce of Vietnam) in mice infected with a P. berghei experimental model. In: Information on Malaria Prevention and Parasite Diseases. Hanoi: National Institute of Malariology, Parasitology and Entomology, internal document, no. 4, pp. 26-32.
-
(2000)
Information on Malaria Prevention and Parasite Diseases
, pp. 26-32
-
-
Tien, N.T.1
Lien, L.K.2
Cong, L.D.3
Nhan, D.H.4
Huong, N.M.5
Hanh, N.T.6
Xuan, D.T.7
Tao, N.D.8
Ha, N.T.H.9
-
29
-
-
0029118855
-
Antimalarial activity of new ethers and thioethers of dihydroartemisinin
-
Vengopalan, B., Karmik, P. J., Bapat, C. P., Chatterjee, D. K., Lyer, N. & Lepcha, D. (1995). Antimalarial activity of new ethers and thioethers of dihydroartemisinin. European Journal of Medicinal Chemistry, 30, 697-706.
-
(1995)
European Journal of Medicinal Chemistry
, vol.30
, pp. 697-706
-
-
Vengopalan, B.1
Karmik, P.J.2
Bapat, C.P.3
Chatterjee, D.K.4
Lyer, N.5
Lepcha, D.6
-
30
-
-
0000955998
-
Study on the chemistry of qinghaosu (artemisinin)
-
Wu, Y. L. & Li, Y. (1995). Study on the chemistry of qinghaosu (artemisinin). Medicinal Chemistry Review, 5, 569-586.
-
(1995)
Medicinal Chemistry Review
, vol.5
, pp. 569-586
-
-
Wu, Y.L.1
Li, Y.2
-
31
-
-
0022219529
-
Studies on systemic pharmacological effects of artesunate
-
Yi Zhao (1985). Studies on systemic pharmacological effects of artesunate. Journal of Tropical Medicine and Hygiene, 88, 391-396.
-
(1985)
Journal of Tropical Medicine and Hygiene
, vol.88
, pp. 391-396
-
-
Zhao, Y.1
|