Synthesis and antimalarial activities of fluoroalkyl derivatives of dihydroartemisinin

Journal of Medicinal Chemistry

Volumn 41, Issue 21, 1998, Pages 4101-4108

  Nga, Truong Thi Thanh ^a   Ménage, Céline ^a   Bégué, Jean Pierre ^a   Bonnet Delpon, Danièle ^a   Gantier, Jean Charles ^b   Pradines, Bruno ^c   Doury, Jean Claude ^c   Thac, Truong Dinh ^d  

^a CNRS   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c SERVICE DE SANTÉ DES ARMÉES   (France)

^d Institut de Chimie Industrielle   (Viet Nam)

Author keywords

[No Author keywords available]

Indexed keywords

10BETA (HEXAFLUOROISOPROPYL)DIHYDROARTEMISININ; 10BETA (PENTAFLUOROPHENOXY)DEHYDROARTEMISININ; 10BETA (PENTAFLUOROPROPYLOXY)DIHYDROARTEMISININ; 10BETA (TRIFLUOROETHOXY)DIHYDROARTEMISININ; ANTIMALARIAL AGENT; DIHYDROARTEMISININ DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; DRUG METABOLISM; DRUG STRUCTURE; DRUG SYNTHESIS; MALARIA; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; STRAIN DIFFERENCE;

ANIMALS; ANTIMALARIALS; ARTEMISININS; DRUG EVALUATION, PRECLINICAL; FEMALE; INHIBITORY CONCENTRATION 50; MALARIA; MICE; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032497703     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9810147     Document Type: Article

References (46)

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