Part 2: Efficient strategies for the construction of variably substituted bicyclo[5.3.1]undecenones (AB-taxane ring systems) and their conversion to tricyclo[9.3.1.03,8]pentadecenones (ABC taxane ring systems) and bicyclo[2.2.2]octanones

Canadian Journal of Chemistry

Volumn 82, Issue 2, 2004, Pages 227-239

  Villalva Servín, Nidia P ^a   Laurent, Alain ^a,b   Fallis, Alex G ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b Aegera Therapeutics   (Canada)

Author keywords

Bicyclo 2.2.2 octanone; Diels alder; Lewis acid; Magnesium chelate; Oxy Cope; Ring closing metathesis; Sigmatropic rearrangement; Taxanes

Indexed keywords

ADDITION REACTIONS; ALCOHOLS; KETONES; ORGANIC ACIDS; SUBSTITUTION REACTIONS;

CYCLOADDITION; DIELS-ALDER REACTIONS (DAR); LEWIS ACID;

SYNTHESIS (CHEMICAL);

BICYCLO COMPOUND; LEWIS ACID; TAXANE DERIVATIVE;

ARTICLE; CARBOMETALLATION; CATALYSIS; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CYCLOADDITION; DIASTEREOISOMER; DIELS ALDER REACTION; MOLECULE; RING CLOSING METATHESIS; STEREOCHEMISTRY; STRUCTURE ANALYSIS; SUBSTITUTION REACTION; SYNTHESIS;

EID: 2342512851     PISSN: 00084042     EISSN: None     Source Type: Journal    
DOI: 10.1139/v03-201     Document Type: Article

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