Shear stress induces expression of vascular endothelial growth factor receptor Flk-1/KDR through the CT-rich Sp1 binding site

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 22, Issue 6, 2002, Pages 907-913

  Abumiya, Takeo ^a   Sasaguri, Toshiyuki ^a   Taba, Yoji ^a   Miwa, Yoshikazu ^a   Miyagi, Megumi ^a  

^a Keiwakai Ebetsu Hospital   (Japan)

Author keywords

Endothelial cells; Gene expression; Shear stress; Transcription factors

Indexed keywords

FETAL LIVER KINASE 1 KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA FLANKING REGION; ENDOTHELIUM CELL; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE MUTATION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SHEAR STRESS;

BINDING SITES; CELLS, CULTURED; CYTOSINE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; HUMANS; LYMPHOKINES; MUTAGENESIS, SITE-DIRECTED; PROMOTER REGIONS (GENETICS); PROTEIN KINASES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, GROWTH FACTOR; RECEPTORS, MITOGEN; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; RHEOLOGY; STRESS, MECHANICAL; THYMINE; UMBILICAL VEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0036075106     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000018300.43492.83     Document Type: Article

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