CRF-receptor 1 blockade attenuates acute posttraumatic hyperglycemia in rats

Journal of Surgical Research

Volumn 119, Issue 1, 2004, Pages 72-79

  Hager, Peter ^a   Hagman, Beth ^a   Wikström, Ann Charlotte ^b   Strömmer, Lisa ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

CP 154; 526; CRF; dexamethasone suppression test; glucose transport; PI 3 kinase; surgical trauma

Indexed keywords

BUTYL[2,5 DIMETHYL 7 (2,4,6 TRIMETHYLPHENYL) 7H PYRROLO[2,3 D]PYRIMIDIN 4 YL]ETHYLAMINE; CORTICOSTERONE; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; DEXAMETHASONE; GLUCOCORTICOID; GLUCOSE; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE;

ANESTHESIA; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG RECEPTOR BINDING; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; HYPERGLYCEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; SKELETAL MUSCLE; SMALL INTESTINE RESECTION; STANDARDIZATION; SURGICAL INJURY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACUTE DISEASE; ADRENOCORTICOTROPIC HORMONE; ANIMALS; BIOLOGICAL TRANSPORT; BLOOD GLUCOSE; CORTICOSTERONE; DEXAMETHASONE; GLUCOCORTICOIDS; GLUCOSE; HYPERGLYCEMIA; INSULIN; MALE; MUSCLE, SKELETAL; PYRIMIDINES; PYRROLES; RATS; RATS, WISTAR; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; WOUNDS AND INJURIES;

EID: 2342472034     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jss.2004.01.012     Document Type: Article

References (44)

1. Black P.R., Brooks D.C., Bessey P.Q., Wolfe R.R., Wilmore D.W. Mechanisms of insulin resistance following injury. Ann. Surg. 196:1982;420
2. Carter E.A. Insulin resistance in burns and trauma. Nutr. Rev. 56:1998;S170
3. Meguid M.M., Aun F., Soeldner J.S. Temporal characteristics of insulin Glucose ratio after varying degrees of stress and trauma in man. J. Surg. Res. 25:1978;389
4. Ljungqvist O., Thorell A., Gutniak M., et al. Glucose infusion instead of preoperative fasting reduces postoperative insulin resistance. J. Am. Coll. Surg. 178:1994;329
5. Thorell A., Nygren J., Essen P., et al. The metabolic response to cholecystectomy insulin resistance after open compared with laparoscopic operation. Eur. J. Surg. 162:1996;187
6. McMahon M., Gerich J., Rizza R. Effects of glucocorticoids on carbohydrate metabolism. Diabetes Metab. Rev. 4:1988;17
7. Chalmers D.T., Lovenberg T.W., De Souza E.B. Localization of novel corticotropin-releasing factor receptor (CRF2) mRNA expression to specific subcortical nuclei in rat brain comparison with CRF1 receptor mRNA expression. J. Neurosci. 15:1995;6340
8. Webster E.L., Lewis D.B., Torpy D.J., et al. In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist suppression of pituitary ACTH release and peripheral inflammation. Endocrinology. 137:1996;5747
9. 2+ influx in rat pancreatic beta-cells. Diabetes. 48:1999;1741
10. Willenberg H.S., Bornstein S.R., Hiroi N., et al. Effects of a novel corticotropin-releasing-hormone receptor type I antagonist on human adrenal function. Mol. Psychiatry. 5:2000;137
11. Lovenberg T.W., Chalmers D.T., Liu C., et al. CRF2 alpha and CRF2 beta receptor mRNAs are differentially distributed between the rat central nervous system and peripheral tissues. Endocrinology. 136:1995;4139
12. Turnbull A.V., Rivier C. Corticotropin-releasing factor (CRF) and endocrine responses to stress CRF receptors, binding protein, and related peptides. Proc. Soc. Exp. Biol. Med. 215:1997;1
13. Strommer L., Permert J., Arnelo U., et al. Skeletal muscle insulin resistance after trauma insulin signaling and glucose transport. Am. J. Physiol. 275:1998;E351
14. Strommer L., Isaksson B., Wickbom M., et al. Effect of carbohydrate feeding on insulin action in skeletal muscle after surgical trauma in the rat. Nutrition. 17:2001;332
15. Shepherd P.R., Withers D.J., Siddle K. Phosphoinositide 3-kinase The key switch mechanism in insulin signalling. Biochem. J. 333:1998;471
16. Tsukamoto H., Reidelberger R.D., French S.W., et al. Long-term cannulation model for blood sampling and intragastric infusion in the rat. Am. J. Physiol. 247:1984;R595
17. Chen Y.L., Mansbach R.S., Winter S.M., et al. Synthesis and oral efficacy of a 4-(butylethylamino)pyrrolo[2, 3-d]pyrimidine A centrally active corticotropin-releasing factor1 receptor antagonist. J. Med. Chem. 40:1997;1749
18. Schulz D.W., Mansbach R.S., Sprouse J., et al. CP-154, 526 A potent and selective nonpeptide antagonist of corticotropin releasing factor receptors. Proc. Natl. Acad. Sci. U S A. 93:1996;10477
19. Nozu T., Martinez V., Rivier J., et al. Peripheral urocortin delays gastric emptying role of CRF receptor 2. Am. J. Physiol. 276:1999;G867
20. Wallberg-Henriksson H., Zetan N., Henriksson J. Reversibility of decreased insulin-stimulated glucose transport capacity in diabetic muscle with in vitro incubation. Insulin is not required. J. Biol. Chem. 262:1987;7665
21. Gumbiner B., Mucha J.F., Lindstrom J.E., et al. Differential effects of acute hypertriglyceridemia on insulin action and insulin receptor autophosphorylation. Am. J. Physiol. 270:1996;E424
22. Goodyear L.J., Giorgino F., Balon T.W., et al. Effects of contractile activity on tyrosine phosphoproteins and PI 3-kinase activity in rat skeletal muscle. Am. J. Physiol. 268:1995;E987
23. Heydrick S.J., Jullien D., Gautier N., et al. Defect in skeletal muscle phosphatidylinositol-3-kinase in obese insulin-resistant mice. J. Clin. Invest. 91:1993;1358
24. Lurie S., Kuhn C., Bartolome J., et al. Differential sensitivity to dexamethasone suppression in an animal model of the DST. Biol. Psychiatry. 26:1989;26
25. Scaccianoce S., Nicolai R., Cigliana G., et al. Reduced glucocorticoid response to corticotropin secretagogues in the aged Sprague-Dawley rat. Neuroendocrinology. 62:1995;32
26. McCarthy J.R., Heinrichs S.C., Grigoriadis D.E. Recent advances with the CRF1 receptor Design of small molecule inhibitors, receptor subtypes and clinical indications. Curr. Pharm. Des. 5:1999;289
27. Makino S., Takemura T., Asaba K., et al. Differential regulation of type-1 and type-2alpha corticotropin-releasing hormone receptor mRNA in the hypothalamic paraventricular nucleus of the rat. Brain Res. Mol. Brain Res. 47:1997;170
28. Matsunaga H., Iguchi A., Yatomi A., et al. The relative importance of nervous system and hormones to the 2-deoxy-D-glucose-induced hyperglycemia in fed rats. Endocrinology. 124:1989;1259
29. Ljungqvist O., Efendic S., Eneroth P., et al. Nutritional status and endocrine response to hemorrhage. Can. J. Physiol. Pharmacol. 64:1986
30. Shimazu T. Neuronal regulation of hepatic glucose metabolism in mammals. Diabetes Metab. Rev. 3:1987;185
31. Nonogaki K., Iguchi A. Role of central neural mechanisms in the regulation of hepatic glucose metabolism. Life Sci. 60:1997;797
32. Cassens G., Roffman M., Kuruc A., et al. Alterations in brain norepinephrine metabolism induced by environmental stimuli previously paired with inescapable shock. Science. 209:1980;1138
33. Curtis A.L., Bello N.T., Connolly K.R., et al. Corticotropin-releasing factor neurones of the central nucleus of the amygdala mediate locus coeruleus activation by cardiovascular stress. J. Neuroendocrinol. 14:2002;667
34. Valentino R.J., Wehby R.G. Corticotropin-releasing factor Evidence for a neurotransmitter role in the locus ceruleus during hemodynamic stress. Neuroendocrinology. 48:1988;674
35. Valentino R.J., Page M.E., Curtis A.L. Activation of noradrenergic locus coeruleus neurons by hemodynamic stress is due to local release of corticotropin-releasing factor. Brain Res. 555:1991;25
36. Saad M.J., Araki E., Miralpeix M., et al. Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance. J. Clin. Invest. 90:1992;1839
37. Bjornholm M., Kawano Y., Lehtihet M., et al. Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation. Diabetes. 46:1997;524
38. Le Marchand-Brustel Y., Tanti J.F., Cormont M., et al. From insulin receptor signalling to Glut 4 translocation abnormalities in obesity and insulin resistance. J. Recept. Signal. Transduct. Res. 19:1999;217
39. Strommer L., Isaksson B., Arnelo U., et al. Preoperative feeding does not reverse postoperative insulin resistance in skeletal muscle in the rat. Metabolism. 49:2000;486
40. Turnbull A.V., Smith G.W., Lee S., et al. CRF type I receptor-deficient mice exhibit a pronounced pituitary-adrenal response to local inflammation. Endocrinology. 140:1999;1013
41. Tilders F.J., Berkenbosch F., Vermes I., et al. Role of epinephrine and vasopressin in the control of the pituitary-adrenal response to stress. Fed. Proc. 44:1985;155
42. Lu C.L., Chan J.S., De Lean A., et al. Metabolic clearence rate and half-time disappearance rate of human terminal and adrenocorticotropin of pro-opiomelanocortin in the rat-a comparative study. Life Sci. 26:1983;2599
43. Judd A.M., Call G.B., Barney M., et al. Possible function of IL-6 and TNF as intraadrenal factors in the regulation of adrenal steroid secretion. Ann. N Y Acad. Sci. 917:2000;628
44. Strommer L., Wickbom M., Wang F., et al. Early impairment of insulin secretion in rats after surgical trauma. Eur. J. Endocrinol. 147:2002;825