Glial growth factor/neuregulin inhibits Schwann cell myelination and induces demyelination

Journal of Cell Biology

Volumn 152, Issue 6, 2001, Pages 1289-1299

  Zanazzi, George ^a   Einheber, Steven ^a   Westreich, Richard ^a   Hannocks, Melanie Jane ^a   Bedell Hogan, Debra ^b   Marchionni, Mark A ^b   Salzer, James L ^a  

^a NEW YORK UNIVERSITY   (United States)

^b CeNeS Pharmaceuticals plc   (United States)

Author keywords

Demyelination; ErbB; Mitogen; Neuregulin; Schwann cell

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE; NEU DIFFERENTIATION FACTOR; NEURITE PROMOTING FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; BASEMENT MEMBRANE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; COCULTURE; CONTROLLED STUDY; DEMYELINATION; ELECTRON MICROSCOPY; IMMUNOFLUORESCENCE; MYELINATION; NERVE DEGENERATION; NONHUMAN; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; RAT; SCHWANN CELL; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; COCULTURE TECHNIQUES; DEMYELINATING DISEASES; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLAST GROWTH FACTOR 2; IMMUNOBLOTTING; LAMININ; MITOGEN-ACTIVATED PROTEIN KINASES; MYELIN SHEATH; NEUREGULIN-1; NEURONS; PHOSPHORYLATION; RATS; RECEPTOR, ERBB-2; RECEPTOR, ERBB-3; SCHWANN CELLS; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0035911970     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.152.6.1289     Document Type: Article

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