PDGFB regulates the development of the labyrinthine layer of the mouse fetal placenta

Developmental Biology

Volumn 212, Issue 1, 1999, Pages 124-136

  Ohlsson, Rolf ^a   Falck, Pierre ^a   Hellström, Mats ^b   Lindahl, Per ^b   Boström, Hans ^b   Franklin, Gary ^a   Ährlund Richter, Lars ^c   Pollard, Jeffrey ^d   Soriano, Philippe ^e   Betsholtz, Christer ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e USA   (United States)

Author keywords

Blood vessels; Labyrinthine; Morphology; Pericytes; Trophoblasts

Indexed keywords

MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL; CONTROLLED STUDY; FETUS; FETUS DEVELOPMENT; GENE EXPRESSION REGULATION; KIDNEY DEVELOPMENT; MESANGIUM CELL; MOUSE MUTANT; NONHUMAN; PERICYTE; PLACENTA DEVELOPMENT; PRIORITY JOURNAL; TROPHOBLAST;

EID: 0033179034     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1999.9306     Document Type: Article

References (33)

1. Bagchus W. M., Hoedemaeker P. J., Rozing J., Bakker W. W. Glomerulonephritis induced by monoclonal anti-Thy 1.1 antibodies. A sequential histological and ultrastructural study in the rat. Lab. Invest. 55:1986;680-687.
2. Bernstein L. R., Antoniades H., Zetter B. R. Migration of cultured vascular cells in response to platelet-derived growth factor. J. Cell Sci. 56:1982;71-82.
3. Betsholtz C., Johnsson A., Heldin C.-H., Westermark B., Lind P., Urdea M. S., Eddy R., Shows T. B., Philpott K., Mellor A. L., Knott T. J., Scott J. cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumor cell line. Nature. 320:1986;695-699.
4. Bidwell M. C., Eitzman B. A., Walmer D. K., McLachlan J. A., Gray K. D. Analysis of messenger ribonucleic acid and protein for the ligands and receptors of the platelet-derived growth factor signaling pathway in the placenta, extraembryonic membranes, and uterus during the latter half of murine gestation. Endocrinology. 136:1995;5189-5201.
5. Boström H., Willetts K., Pekny M., Levéen P., Lindahl P., Hedstrand H., Pekna M., Hellström M., Gebre-Medhin S., Schalling M., Nilsson M., Kurland S., Törnell J., Heath J. K., Betsholtz C. PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis. Cell. 85:1996;863-873.
6. Crosby J. R., Seifert R. A., Soriano P., Bowen-Pope D. F. Chimaeric analysis reveals role of Pdgf receptors in all muscle lineages. Nat. Genet. 18:1998;385-388.
7. D'Amore P. A., Smith S. R. Growth factor effects on cells of the vascular wall: A survey. Growth Factors. 8:1993;61-75.
8. DeHoff R. T., Rhines F. N. Quantitative Microscopy. 1968;McGraw-Hill, New York.
9. Dickson M. C., Martin J. S., Cousins F. M., Kulkarni A. B., Karlsson S., Akhurst R. J. Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knockout mice. Development. 121:1995;1845-1854.
10. Goustin A. S., Betzholtz C., Pfeifer-Ohlsson S., Persson H., Rydnert J., Bywater M., Holmgren G., Heldin C. H., Westermark B., Ohlsson R. Coexpression of the sis and myc proto-oncogenes in developing human placenta suggests autocrine control of trophoblast growth. Cell. 41:1985;301-312.
11. Hammacher A., Mellström K., Heldin C.-H., Westermark B. Isoform-specific induction of actin reorganization by platelet-derived growth factor suggests that the functionally active receptor is a dimer. EMBO J. 8:1989;2489-2495.
12. Heldin C.-H., Westermark B. Platelet-derived growth factor: Three isoforms and two receptor types. Trends Genet. 5:1989;108-111.
13. Heldin C.-H., Westermark B. Platelet-derived growth factor: Mechanism of action and possible in vivo function. Cell Regul. 1:1990;555-566.
14. Holmgren L., Glaser A., Pfeifer-Ohlsson S., Ohlsson R. Angiogenesis of human extraembryonic tissue involves the spatiotemporal control of PDGF ligand and receptor genes. Development. 133:1991;749-754.
15. Holmgren L., Claesson-Welsh L., Heldin C.-H., Ohlsson R. The expression of PDGF α- and β-receptors in subpopulations of PDGF-producing cells implicates autocrine stimulatory loops in the control of proliferation of active cytotrophoblasts that have invaded the uterine lining. Growth Factors. 6:1992;219-231.
16. Holmgren L., Flam F., Larsson E., Ohlsson R. Successive activation of the platelet-derived growth factor beta receptor and platelet-derived growth factor B genes correlates with the genesis of human choriocarcinoma. Cancer Res. 53:1993;2927-2931.
17. Jollie W. P. Fine structure changes in the placental labyrinth of the rat with increasing gestational age. J. Ultrastruct. Res. 10:1964;27-47.
18. Khachigian L., Lindner V., Williams A. J., Collins T. Egr-1-induced endothelial gene expression: A common theme in vascular injury. Science. 271:1996;1427-1431.
19. Levéen P., Pekny M., Gebre-Medhin S., Swolin B., Larsson E., Betsholtz C. Mice deficient for PDGF-B show renal, cardiovascular and hematological abnormalities. Genes Dev. 8:1994;1875-1887.
20. Lindahl P., Johansson B. R., Levéen P., Betsholtz C. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science. 277:1997a;242-245.
21. Lindahl P., Karlsson L., Hellström M., Gebre-Medhin S., Willetts K., Heath J. K., Betsholtz C. Alveogenesis failure in PDGF-A deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development. Development. 124:1997b;3943-3953.
22. Lindahl P., Hellström M., Kalén M., Karlsson L., Pekny M., Pekna M., Soriano P., Betsholtz C. Paracrine PDGF-B/PDGF-Rβ signaling controls mesangial cell development in kidney glomeruli. Development. 125:1998;3313-3322.
23. Mercola M., Wang C., Kelly J., Brownlee C., Jackson-Grusby L., Stiles C., Bowen-Pope D. F. Selective expression of PDGF-A and its receptor during early mouse embryogenesis. Dev. Biol. 138:1990;114-122.
24. Ohlsson R., Larsson E., Nilsson O., Wahlström T., Sundström P. Blastocyst implantation precedes induction of insulin-like growth factor II gene expression in human trophoblasts. Development. 106:1989;555-559.
25. Palmieri S. L., Pagne J., Stiles C. D., Biggers J. D., Mercola M. Expression of mouse PDGF-A and PDGF-α-receptor genes during pre- and post-implantation development. Evidence for a developmental shift from an autocrine to a paracrine mode of action. Mech. Dev. 39:1992;181-191.
26. Raines E. W., Bowen-Pope D. F., Ross R. Platelet-derived growth factor. Sporn M. B., Roberts A. B. Handbook of the Experimental Pharmacology. Peptide Growth Factors and Their Receptors. 1990;173-262 Springer-Verlag, Heidelberg.
27. Raines E. W., Ross R. Platelet-derived growth factor in vivo. Westmark B., Sorg C. Biology of Platelet-Derived Growth Factor. 1993;74-114 Karger, Basel.
28. Roberts W. M., Look A. T., Sherr C. J. Tandem linkage of human CSF-1 receptor (c-fms) and the PDGF receptor genes. Cell. 55:1988;655-661.
29. Ross R., Raines E. W., Bowen P. D. The biology of platelet-derived growth factor. Cell. 46:1986;155-169.
30. Soriano P. Abnormal kidney development and hematological disorders in PDGFB-receptor mutant mice. Genes Dev. 8:1994;1888-1896.
31. Soriano P. The PDGF α receptor is required for neural crest cell survival and for normal patterning of the somites. Development. 124:1997;2691-2700.
32. Uiker S., Kriz W. Structural analysis of the formation of glomerular microaneurysms in the Habu venom model. Virchows Arch. 426:1995;281-293.
33. Yarden Y., Escobedo J. A., Kuang W.-J., Yang-Feng T. L., Daniel T. O., Tremble P. M., Chen E. Y., Ando M. E., Harkins R. A., Francke U., Fried V. A., Ullrich A., Williams L. T. Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors. Nature. 323:1986;226-232.