Structure-Function Analysis of the Reactive Site in the First Kunitz-type Domain of Human Tissue Factor Pathway Inhibitor-2

Journal of Biological Chemistry

Volumn 279, Issue 17, 2004, Pages 17500-17507

  Chand, Hitendra S ^a   Schmidt, Amy E ^b   Bajaj, S Paul ^b   Kisiel, Walter ^a,c  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^b JOINT REPLACEMENT INSTITUTE   (United States)

^c UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COAGULATION; ENZYMES; HYDROPHOBICITY; MODAL ANALYSIS; MUTAGENESIS; TISSUE;

FIBRINOLYSIS; REACTIVE SITES;

GENETIC ENGINEERING;

APROTININ; ARGININE; ASPARTIC ACID; BLOOD CLOTTING FACTOR 7A; GLUTAMIC ACID; LEUCINE; METHIONINE; PHENYLALANINE; PLACENTA PROTEIN 5; PLASMIN; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; THROMBOPLASTIN; TRYPSIN; TYROSINE;

ARTICLE; BLOOD CLOTTING; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENERGY TRANSFER; ENZYME KINETICS; ENZYME SPECIFICITY; FIBRINOLYSIS; HUMAN; HYDROPHOBICITY; MOLECULAR INTERACTION; MOLECULAR MODEL; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; ARGININE; ASPARTIC ACID; BINDING SITES; CATTLE; CRYSTALLOGRAPHY, X-RAY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FACTOR VIIA; GLYCOPROTEINS; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PLASMIN; POINT MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPSIN; TYROSINE;

BOVINAE;

EID: 2342419730     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M400802200     Document Type: Article

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