The inflammatory reaction in human traumatic oedematous cerebral cortex

Journal of Submicroscopic Cytology and Pathology

Volumn 37, Issue 1, 2005, Pages 43-52

  Castejon O J ^a   Castellano, A ^a   Arismendi, G J ^a   Medina, Z ^b  

^a UNIVERSIDAD DEL ZULIA   (Venezuela)

^b UNIVERSIDAD DEL ZULIA   (Venezuela)

Author keywords

Brain trauma; Inflammatory reaction; Light and electron microscopy; Macrophages; Microglia; Monocytes

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; BRAIN CORTEX; BRAIN EDEMA; BRAIN INJURY; FEMALE; HUMAN; INFLAMMATION; MACROPHAGE; MALE; MICROGLIA; MIDDLE AGED; MONOCYTE; PATHOLOGY; PHAGOCYTOSIS; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BRAIN EDEMA; BRAIN INJURIES; CEREBRAL CORTEX; FEMALE; HUMANS; INFLAMMATION; MACROPHAGES; MALE; MICROGLIA; MICROSCOPY, ELECTRON, TRANSMISSION; MIDDLE AGED; MONOCYTES; PHAGOCYTOSIS;

EID: 23244456635     PISSN: 11229497     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (76)

1. ADELSON P.D., WHALEN M.J., KOCHNAEK P.M., ROBICHAUD P. and CARLOS T.M., 1998. Blood brain barrier permeability and acute inflammation in two models of traumatic brain injury in the immature rat: a preliminary report. Acta Neurochir. Suppl., 71, 104-106.
2. ALDSKOGIUS H., 2001. Microglia in neuroregeneration. Microsc. Res. Tech., 54, 40-46.
3. ANDERSON W.R., MARTELLA A., DRAKE Z.M., HU S., PETERSON P.K. and CHAO C.C., 1995. Correlative transmission and scanning electron microscopy study of microglia activated by interferon-gamma and tumor necrosis factor-alpha in vitro. Pathol. Res. Pract., 191, 1016-1022.
4. AYOUB A.E. and SALM A.K., 2003. Increased morphological diversity of microglia in the activated hypothalamic supraoptic nucleus. J. Neurosci., 23, 7759-7766.
5. BESCHORNER R., NGUYEN T.D., GOZALAN F., PEDAL I., MATTERN R., SCHLUESENER H.J., MEYERMANN R. and SCHWAB J.M., 2002. CD14 expression by activated parenchymal microglia/macrophages and infiltrating monocytes following human traumatic brain injury. Acta Neuropathol., 103, 541-549.
6. CASTEJÓN O.J., 1980. Electron microscopic study of capillary wall in human cerebral edema. J. Neuropath. Exper. Neurol., 39, 296-327.
7. CASTEJÓN O.J., 2003. Synaptic plasticity in the oedematous human cerebral cortex. J. Submicrosc. Cytol. Pathol., 35, 177-197.
8. CASTEJÓN O.J., and CASTEJÓN H.V., 2000. Oligodendroglial cell behaviour in traumatic oedematous human cerebral cortex: a light and electron microscopic study. Brain Inj., 4, 303-317.
9. CASTEJÓN O.J., VALERO C. and DÍAZ M., 1997. Light and electron microscopic study of nerve cells in traumatic oedematous human cerebral cortex. Brain Inj., 11, 363-388.
10. CASTEJÓN O.J., CASTEJÓN H.V., DÍAZ M. and CASTELLANO A., 2001. Consecutive light microscopy, scanning-transmission electron microscopy and transmission electron microscopy of traumatic human brain oedema and ischaemic brain damage. Histol. Histopathol., 26, 1117-1134.
11. CHODOBSKI A., CHUNG I., KOZNIEWSKA E., IVANENKO T., CHANG W., HARRINGTON J.F., DUNCAN J.A. and SZMYDYNGER-CHODOBSKA J., 2003. Early neutrophilic expression of vascular endothelial growth factor after traumatic brain injury. Neuroscience, 122, 853-867.
12. CHU K., JEON S.W., JUNG K.H., HAN S.Y., LEE S.T., KIM M. and ROH J., 2004. Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death. J. Cereb. Blood Flow Metab., 24, 926-933.
13. CROSS A.K. and WOODROOFE N.M., 2001. Immunoregulation of microglial functional properties. Microsc. Res. Tech., 54, 1, 10-17.
14. DAVIS E.J., FOSTER T.D. and THOMAS W.E., 1994. Cellular forms and functions of brain microglia. Brain Res. Bull., 34, 73-78.
15. ENGEL S., WEHNER H.D. and MEYERMANN R., 1996. Expression of microglial markers in the human CNS after closed head injury. Acta Neurochir. (Suppl.), 66, 89-95.
16. ENGEL S., SCHLUESENER H., MITTELBRONN M., SEID K., ADJODAH D., WEHNER H.I. and MEYERMANN R., 2000. Dynamics of microglial activation after human traumatic brain injury are revealed by delayed expression of macrophage-related proteins MRP8 and MRP14. Acta Neuropathol., 100, 313-322.
17. FLARIS N.A., DENSMORE T.L., MOLLESTON M.C. and HICKEY W.F., 1993. Characterization of microglia and macrophages in the central nervous system of rats: Definition of the differential expression of molecules using standard and novel monoclonal antibodies in normal CNS and in four models of parenchymal reaction. Glia, 7, 34-40.
18. FOTHERINGHAM A.P., DAVIES C.A. and DAVIES I., 2000. Oedema and glial cell involvement in the aged mouse brain after permanent focal ischaemia. Neuropathol. Appl. Neurobiol., 26, 412-423.
19. FRANCEL P.C., 1992. Bradykinin and neuronal injury. J. Neurotrauma (Suppl. 1), S27-45-45.
20. FUJITA S., TSUCHIHASHI Y. and KITAMURA T., 1981. Origin, morphology and function of the microglia. In: 'Glial and Neuronal Cell Biology'. Acosta Vidrio E. and Fedoroff S. eds., Alan R. Liss Inc., New York, USA, pp. 141-169.
21. FUJITA T., YOSHIMINE T., MARUNO M. and HAYAKAWA T., 1998. Cellular dynamics of macrophages and microglial cells in reaction to stab wounds in rat cerebral cortex. Acta Neurochirur., 140, 275-279.
22. GARDENFORS A., NILSSON F., SKAGERBERG G., UNGERSTEDT U. and NORDSTROM CH., 2002. Cerebral physiological and biochemical changes during vasogenic brain oedema induced by intrathecal injection of bacterial lipopolysaccharides in piglets. Acta Neurochir., 144, 601-608.
23. GEHRMANN J., MATSUMOTO Y. and KREUTZBERG G.W., 1995a. Microglia: intrinsic immuneffector cell of the brain. Brain Res. Brain Res. Rev., 20, 269-287.
24. GEHRMANN J., BANATI R.B., WIESSNER C., HOSSMANN K.A. and KREUTZBERG G.W., 1995b. Reactive microglia in cerebral ischaemia: an early mediator of tissue damage?. Neuropathol. Appl. Neurobiol., 21, 277-289.
25. GLABINSKI A., KRAJEWSKI S. and RAFALOWSKA J., 1998. Tumor necrosis factor-alpha induced pathology in the rat brain: characterization of stereotaxic injection model. Folia Neuropathol., 36, 52-62.
26. GONG C., HOFF J.T. and KEEP R.F., 2000. Acute inflammatory reaction following experimental intracerebral hemorrhage in rat. Brain Res., 14, 57-65.
27. GIORDANA M.T., ATTANASIO A., CAVALLA P., MIGHELI A., VIGLIANI M.C. and SCHIFFER D., 1994. Reactive cell proliferation and microglia following injury to the rat brain. Neuropathol. Appl. Neurobiol., 20, 163-174.
28. GONZALEZ-SCARANO F. and BALTUCH G., 1999. Microglia as mediators of inflammatory and degenerative diseases. Ann. Rev. Neurosci., 22, 219-240.
29. GUILIAN D., 1995. Microglia and neuronal dysfunction. In: 'Neuroglia'. Kettenmann H.K. and Ransom B.R. eds., Oxford University Press, New York, pp. 671-684.
30. GUIROY D.C., WAKAYAMA I., LIBERSKI P.P. and GAJDUSEK D.C., 1994. Relationship of microglia and scrapie amyloid-immunoreactive plaques in kuru, Creutzfeldt-Jakob disease and Gerstmann-Straussler syndrome. Acta Neuropathol., 87, 526-530.
31. HAIRI R.J., 1994. Cerebral edema. Neurosurg. Clin. N. Am., 5, 687-706.
32. HAMPTON D.W., RHODES K.E., ZHAO C., FRANKLIN R.J.M. and FAWCETT J.W., 2004. The responses of oligodendrocyte precursor cells, astrocytes and microglia to a cortical stab injury, in the brain. Science Direct-Neuroscience (IBRO), pp. 813-820.
33. HERMANN D.M., MIES G., HATA R. and HOSSMANN K.A., 2000. Microglial and astrocytic reactions prior to onset of thalamic cell death after traumatic lesion of the rat sensorimotor cortex. Acta Neuropathol, 99, 147-153.
34. HIRANO A., KAWANAMI T and LLENA J.F., 1994. Electron microscopy of the blood-brain barrier in disease. Microsc. Res. Tech., 27, 543-556.
35. HOFFMANN A., KANN O., OHLEMEYER C., HANISCH U.K. and KETTENMANN H., 2003. Elevation of basal intracellular calcium as a central element in the activation of brain macrophages (microglia): Suppression of receptor-evoked calcium signalling and control of release function. J. Neurosci., 23, 4410-4419.
36. HOLMIN S. and MATHIESEN T., 2000. Intracerebral administration of interleukin-1beta and induction of inflammation, apoptosis, and vasogenic edema. J. Neurosurg., 92, 108-120.
37. HTAIN W.W., LEONG S.K. and LING E.A., 1994. A comparative Mac-1 immuno-cytochemical and lectin histochemical study of microglial cells in the normal and athymic mice. Glia, 12, 44-51.
38. KADOTA E., MURAMATSU Y., NONAKA K., KARUSUNO M., NISHI K., DOTE K. and HASHIMOTO S., 2000. Biological functions of extravasated serum IgG in rat brain. Acta Neurochir. (Suppl.), 76, 69-72.
39. KATO H. and WALZ W., 2000. The initiation of the microglial response. Brain Pathol., 10, 137-143.
40. KAUR C. and YOU Y., 2000. Ultrastructure and function of the amoeboid microglial cells in the periventricular white matter in postnatal rat brain following a hypoxic exposure. Neurosci. Lett., 290, 17-20.
41. KAUR C., SINGH J., LIM M.K., NG B.L. and LING E.A., 1997. Macrophages/microglia as 'sensors' of injury in the pineal gland of rats following a non-penetrative blast. Neurosci. Res., 27, 317-322.
42. KIPRIANOVA I., SCHWAB S., FANDREY J. and SPRANGER M., 1997. Suppression of the oxidative burst in murine microglia by nitric oxide. Neurosci. Lett., 226, 75-78.
43. KREUTZBERG G.W., 1995. Microglia, the first line of defence in brain pathologies. Arzneimittelforschung, 45, 357-360.
44. KREUTZBERG G.W., 1996. Microglia: a sensor for pathological events in the CNS. Trends Neurosci., 19, 312-318.
45. KUSHI H., SAITO T., MAKING K. and HAYASHI N., 2003. Neuronal damage in pericontusional edema zone. Acta Neurochir. Suppl., 86, 339-342.
46. LI Y., FIELD P.M. and RAISMAN G., 1999. Death of oligodendrocytes and microglial phagocytosis of myelin precede immigration of Schwann cells into the spinal cord. J. Neurocytol., 28, 417-427.
47. LIU H.M. and CHEN H.H., 1994. Correlation between fibroblast growth factor expression and cell proliferation in experimental brain infart: studied with proliferation cell nuclear antigen immunohistochemistry. J. Neuropathol. Exp. Neurol., 53, 118-126.
48. MASADA T., HUA Y., XI G., YANG G.Y., HOFF J.T. and KEEP R.F., 2001. Attenuation of intracerebral hemorrhage and thrombin-induced brain edema by overexpression of interleukin-1 receptor antagonist. J. Neurosurg., 85, 5680-5686.
49. MASADA T., HUA Y., Xi G., YANG G.Y., HOFF J.T., KEEP R.F., and NAGAO S., 2003. Overexpression of interleukin-1 receptor antagonist reduces brain edema induced by intracerebral hemorrhage and thrombin. Acta Neurochir. Suppl. 86, 463-467.
50. MATZ P., TURNER C., WEINSTEIN P.R., MASSA S.M., PANTER S.S. and SHARP F.R., 1996. Heme-oxygenase-1 induction in glia throughout rat brain following experimental subarachnoid hemorrhage. Brain Res., 713, 211-222.
51. MONTEIRO R.A., ROCHA E. and MARINI-ABREU M.M., 1996. Do microglia arise from pericytes? An ultrastructural and distribution study in the rat cerebellar cortex. J. Submicrosc. Cytol. Pathol., 28, 457-469.
52. NAKANISHI H., 2003. Microglial functions and proteases. Mol. Neurobiol., 27, 163-176.
53. NAKAJIMA K. and KOHSAKA S., 2001. Microglia: activation and their significance in the central nervous system. J. Biochem., 130, 169-175.
54. NARUSE H., TANAKA K., NISHIMURA S. and FUGIMOTO K., 1990. A microstructural study of oedema resolution. Acta Neurochir. Suppl., 51, 87-89.
55. PERRY V.H., BROWN M.C. and GORDON S., 1987. The macrophage response to central and peripheral nerve injury. A possible role for macrophages in regeneration. J. Exper. Med., 165, 1218-1223.
56. POPOVICH P.G., GUAN Z., MCGAUGHY V., FISHER L., HICKEY W.F. and BASSO D.M., 2002. The neuropathological and behavioral consequences of intraspinal microglial/macrophage activation. J. Neuropathol. Exp. Neurol., 61, 623-633.
57. RAIVICH G., HAAS S., WERNER A., KLEIN M.A., KLOSS C. and KREUTZBERG G.W., 1998. Regulation of MCF receptors on microglia in the normal and injured mouse central nervous system: a quantitative immunofluorescence study using confocal laser microscopy. J. Comp. Neurol., 395, 342-358.
58. RAIVICH G., BOHATSCHEK M., KLOSS C.U., WERNER A., JONES L.L., KREUTZBERG G.W., 1999. Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function. Brain Res. Rev., 30, 77-105.
59. ROJIANI A.M., CHO E.S., SHARER L. and PRINEAS J.W., 1994. Electrolyte-induced demyelination in rats. 2. Ultrastructural evolution. Acta Neuropathol., 88, 293-299.
60. SAUKKONEN K., SANDE S., CIOFFE C., WOLPE S., SHERRY B., CERAMI A. and TUOMANEN E., 1990. The role of cytokines in the generation of inflammation and tissue damage in experimental gram-positive meningitis. J. Exp., Med., 171, 439-448.
61. SKIBO G.G., NIKONENKO I.R., SAVCHENKO V.L. and MACKANNA J.A., 2000. Microglia in organotypic hippocampal slice culture and effects of hypoxia: ultrastructure and lipocortin-1 immunoreactivity. Neuroscience, 96, 427-438.
62. SMITH M.E., 1993. Phagocytosis of myelin by microglia in vitro. J. Neurosci. Res., 35, 480-487.
63. STREIT W.J., 1996. The role of microglia in brain injury. Neurotoxicol., 17, 671-678.
64. STREIT W.J., 2000. Microglial response to brain injury: a brief synopsis. Toxicol. Pathol., 28, 28-30.
65. STREIT W.J., 2002a. Microglia and the response to brain injury. In: 'Neuroinflammation. From Bench to Bedside'. Kettenmann H., Burton G.A. and Moenning U.J. eds., Ernst Schering Research Foundation, Springer, Berlin, pp. 11-24.
66. STREIT W.J., 2002b. Microglia as neuroprotective, immunocompetent cells of the CNS. Glia, 40, 133-139.
67. STREIT W.J., GRAEBER M.B. and KREUTZBERG G.W., 1988. Functional plasticity of microglia: a review. Glia, 1, 301-307.
68. STOLL G. and JANDER S., 1999. The role of microglia and macrophages in the pathophysiology of the CNS. Prog. Neurobiol., 58, 233-247.
69. SUZUKI K., MASAWA N. and TAKATAMA M., 2001. The pathogenesis of cerebrovascular lesions in hypertensive rats. Med. Electron Microsc., 34, 230-239.
70. TOULMOND S., DUVAL D., SERRANO A., SCATTON B. and BENAVIDES J., 1993. Biochemical and histological alterations induced by fluid percussion brain injury in the rat. Brain Res., 620, 31-34.
71. THOMAS W.E., 1999. Brain macrophages: on the role of pericytes and perivascular cells. Brain Res. Rev., 31, 42-57.
72. TONG W., IGARASHI T., FERRIERO D.M. and NOBLE L.J., 2002. Traumatic brain injury in the immature mouse brain: characterization of regional vulnerability. Exp. Neurol., 176, 105-116.
73. VAUGHN J.E. and SKOFF R.P., 1972. Neuroglia in experimentally altered central nervous system. In: 'The Structure and Function of Nerve Tissue'. Bourne G.H. ed., Academic Press, New York, 1972, pp. 39-70.
74. WANG J., TAKEUCHI K. and OOKAWARA S., 2003. Changes of perivascular macrophages in the process of brain edema induced by cold injury. Acta Neurochir. Suppl., 86, 281-285.
75. YANG M.S., PARK E.J., SOHN S., KWON H.J., SHIN W.H., PYO H.K., JIN B., CHOI K.S., JOU I. and JOE E.H., 2002. Interleukin-13 and -4 induce death of activated microglia. Glia, 38, 273-280.
76. ZHANG S.CH. and FEDOROFF S., 1996. Neuron-microglia interactions in vitro. Acta Neuropathol., 91, 385-395.