The pathogenesis of cerebrovascular lesions in hypertensive rats

Medical Electron Microscopy

Volumn 34, Issue 4, 2001, Pages 230-239

  Suzuki, Keiji ^a   Masawa, Nobuhide ^a   Takatama, Masamitu ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

Adhesion molecule; Cerebrovascular lesion; Cytokine; Hypertension; Leukocyte

Indexed keywords

CD31 ANTIGEN; FIBRIN DERIVATIVE; HORSERADISH PEROXIDASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA; ARTERY MEDIA; ARTICLE; BRAIN ARTERY; BRAIN EDEMA; BRAIN HEMORRHAGE; CELL ACTIVATION; CELL DAMAGE; CELL INVASION; CELL JUNCTION; CELL MEMBRANE PERMEABILITY; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; ENDOTHELIUM CELL; HYPERTENSION; IMMUNOHISTOCHEMISTRY; LEUKOCYTE ADHERENCE; MALE; MICROSCOPY; MONOCYTE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PATHOGENESIS; PINOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCANNING ELECTRON MICROSCOPY; THROMBOCYTE; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ANTIGENS, CD31; CELL ADHESION; CEREBRAL ARTERIES; ENDOTHELIUM, VASCULAR; HYPERTENSION; INTERCELLULAR ADHESION MOLECULE-1; MALE; MICROSCOPY, ELECTRON, SCANNING; NEUTROPHILS; RATS; RATS, WISTAR;

EID: 0035738801     PISSN: 09184287     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007950100020     Document Type: Article

References (35)

1. Increased permeability of the arteries in hypertensive rats: An electron microscopic study
2. Endothelial changes of hypertensive rat mesenteric arteries
3. Ultrastructural studies on arteriolar lesions in experimental hypertension
4. Cerebral arterial lesions in experimental hypertensive rats: Electron microscopic study of middle cerebral arteries
5. Adhesion molecule and cytokines of hypertensive rat arteries
6. Induction by IL-1 and interferon-gamma: Tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1)
7. Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells
8. Induction of ICAM-1 by TNF-alpha, IL-1 beta, and LPS in human endothelial cells after downregulation of PKC
9. The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: Ultrastructural cytochemistry by a new technique
10. Neutrophilmediated damage to vascular endothelium in the spontaneously hypertensive rat
11. Neutrophil-mediated endothelial injury: In vitro mechanisms of cell detachment
12. Tissue destruction by neutrophils
13. Relations monocytes-endothelium
14. Circulating leukocyte counts, activation, and degranulation in Dahl hypertensive rats
15. Endothelial-leukocyte adhesion molecules
16. Adhesion molecules and inflammatory injury
17. The expression of the adhesion molecules ICAM-1, VCAM-1, PECAM, and E-selectin in human atherosclerosis
18. Cytokines and reperfusion injury
19. Adhesion molecules on normotensive and hypertensive rat brain endothelial cells
20. Evidence for activation of endothelium and monocytes in hypertensive rats
21. Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells
22. Fluid shear stress modulates surface expression of adhesion molecules by endothelial cells
23. Flow stimulates ICAM-1 expression time and shear stress dependently in cultured human endothelial cells
24. Leukocyte infiltration and ICAM-1 expression in two-kidney one-clip hypertension
25. Shear stress increases the release of interleukin-1 and interleukin-6 by aortic endothelial cells
26. Molecular and cellular properties of PECAM-1 (endoCAM/CD31): A novel vascular cell-cell adhesion molecule
27. Ultrastructural and morphometric studies related to expression of the cell adhesion molecule PECAM-1/CD31 in developing rat lung
28. Transendothelial migration of monocytes in rat aorta: Distribution of F-actin, α catenin, LFA-1, and PECAM-1
29. PECAM-1 is required for transendothelial migration of leukocytes
30. IL-8 causes in vivo neutrophil migration by a cell-dependent mechanism
31. Regulation of transendothelial neutrophil migration by endogenous interleukin-8
32. Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-alpha, LPS, and IL-1 beta
33. Effects of interleukin-1 alpha on migration of canine neutrophils in vitro and in vivo
34. Multifunctional cytokine expression by human coronary endothelium and regulation by monokines and glucocorticoids
35. Migration of neutrophils across endothelial monolayers is stimulated by treatment of the monolayers with interleukin-1 or tumor necrosis factor-alpha