Influence of bisphosphonates on the production of pro-inflammatory cytokines by activated human articular chondrocytes

Cytokine

Volumn 31, Issue 4, 2005, Pages 298-304

  Van Offel, Jan F ^a   Dombrecht, Evelyne J ^a   Bridts, Chris H ^a   Schuerwegh, Annemie J ^a   Ebo, Didier G ^a   Stevens, Wim J ^a   De Clerck, Luc S ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Arthritis; Bisphosphonates; Cartilage; Chondrocytes; Cytokines

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; CLODRONIC ACID; CYTOKINE; DEXAMETHASONE; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12P70; INTERLEUKIN 6; INTERLEUKIN 8; MICROSPHERE; PAMIDRONIC ACID; RISEDRONIC ACID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CARTILAGE; CARTILAGE CELL; CELL ACTIVATION; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; EXPLANT; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOASSAY; INCUBATION TIME; INFLAMMATION; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN INDUCTION; PROTEIN SYNTHESIS INHIBITION; SUPERNATANT;

CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; DEXAMETHASONE; DIPHOSPHONATES; FLOW CYTOMETRY; HUMANS; INTERLEUKINS; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 23244455115     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2005.05.009     Document Type: Article

References (63)

1. D.M. Lee, and M.E. Weinblatt Rheumatoid arthritis Lancet 358 2001 903 911
2. P.A. Guerne, D.A. Carson, and M. Lotz IL-6 production by human articular chondrocytes. Modulation of its synthesis by cytokines, growth factors, and hormones in vitro J Immunol 144 1990 499 505
3. Y.E. Henrotin, D.D. De Groote, A.H. Labasse, S.E. Gaspar, S.X. Zheng, and V.G. Geenen Effects of exogenous IL-1 beta, TNF alpha, IL-6, IL-8 and LIF on cytokine production by human articular chondrocytes Osteoarthritis Cartilage 4 1996 163 173
4. P. Borden, D. Solymar, A. Sucharczuk, B. Lindman, P. Cannon, and R.A. Heller Cytokine control of interstitial collagenase and collagenase-3 gene expression in human chondrocytes J Biol Chem 271 1996 23577 23581
5. S.M. Krane, W. Conca, M.L. Stephenson, E.P. Amento, and M.B. Goldring Mechanisms of matrix degradation in rheumatoid arthritis Ann N Y Acad Sci 580 1990 340 354
6. M. Cao, A. Westerhausen-Larson, C. Niyibizi, K. Kavalkovich, H.I. Georgescu, and C.F. Rizzo Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: prolyl hydroxylase as a possible target Biochem J 324 1997 305 310
7. M. Lotz The role of nitric oxide in articular cartilage damage Rheum Dis Clin North Am 25 1999 269 282
8. Y. Jiang, H.K. Genant, I. Watt, M. Cobby, B. Bresnihan, and R. Aitchison A multicenter, double-blind, dose-ranging, randomized, placebo-controlled study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis: radiologic progression and correlation of Genant and Larsen scores Arthritis Rheum 43 2000 1001 1009
9. B. Bresnihan, J.M. Alvaro-Gracia, M. Cobby, M. Doherty, Z. Domljan, and P. Emery Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist Arthritis Rheum 41 1998 2196 2204
10. S. Cohen, E. Hurd, J. Cush, M. Schiff, M.E. Weinblatt, and L.W. Moreland Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate: results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial Arthritis Rheum 46 2002 614 624
11. J.M. Bathon, R.W. Martin, R.M. Fleischmann, J.R. Tesser, M.H. Schiff, and E.C. Keystone A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis N Engl J Med 343 2000 1586 1593
12. P.E. Lipsky, D.M. van der Heijde, E.W. St.Clair, D.E. Furst, F.C. Breedveld, and J.R. Kalden Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study group N Engl J Med 343 2000 1594 1602
13. F.C. Breedveld, P. Emery, E. Keystone, K. Patel, D.E. Furst, and J.R. Kalden Infliximab in active early rheumatoid arthritis Ann Rheum Dis 63 2004 149 155
14. L.A. Joosten, M.M. Helsen, T. Saxne, F.A. van De Loo, D. Heinegard, and W.B. van Den Berg IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation J Immunol 163 1999 5049 5055
15. J.M. Dayer, B. de Rochemonteix, B. Burrus, S. Demczuk, and C.A. Dinarello Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells J Clin Invest 77 1986 645 648
16. J.M. Dayer Interleukin 1 or tumor necrosis factor-alpha: which is the real target in rheumatoid arthritis? J Rheumatol Suppl 65 2002 10 15
17. I. Yaron, F.A. Meyer, J.M. Dayer, I. Bleiberg, and M. Yaron Some recombinant human cytokines stimulate glycosaminoglycan synthesis in human synovial fibroblast cultures and inhibit it in human articular cartilage cultures Arthritis Rheum 32 1989 173 180
18. C. Sanchez, M.M. Mateus, M.P. Defresne, J.M. Crielaard, J.Y. Reginster, and Y.E. Henrotin Metabolism of human articular chondrocytes cultured in alginate beads. Longterm effects of interleukin 1beta and nonsteroidal antiinflammatory drugs J Rheumatol 29 2002 772 782
19. S. Bender, H.D. Haubeck, E. Vandeleur, G. Dufhues, X. Schiel, and J. Lauwerijns Interleukin-1-beta induces synthesis and secretion of interleukin-6 in human chondrocytes FEBS Lett 263 1990 321 324
20. C.M. De Gendt, L.S. De Clerck, C.H. Bridts, A. Verbruggen, and W.J. Stevens Influence of antirheumatic drugs on nitric oxide and interleukin 8 production in human articular chondrocytes J Rheumatol 25 1998 536 538
21. J. Van Damme, R.A. Bunning, R. Conings, G. Russell, and G. Opdenakker Characterization of granulocyte chemotactic activity from human cytokine-stimulated chondrocytes as interleukin 8 Cytokine 2 1990 106 111
22. A.D. Recklies, and E.E. Golds Induction of synthesis and release of interleukin-8 from human articular chondrocytes and cartilage explants Arthritis Rheum 35 1992 1510 1519
23. L. Pulsatelli, P. Dolzani, A. Piacentini, T. Silvestri, R. Ruggeri, and G. Gualtieri Chemokine production by human chondrocytes J Rheumatol 26 1999 1992 2001
24. S.C. Manolagas, and R.L. Jilka Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis N Engl J Med 332 1995 305 311
25. A. Jikko, T. Wakisaka, M. Iwamoto, H. Hiranuma, Y. Kato, and T. Maeda Effects of interleukin-6 on proliferation and proteoglycan metabolism in articular chondrocyte cultures Cell Biol Int 22 1998 615 621
26. J.J. Nietfeld, B. Wilbrink, M. Helle, J.L. van Roy, W. den Otter, and A.J. Swaak Interleukin-1-induced interleukin-6 is required for the inhibition of proteoglycan synthesis by interleukin-1 in human articular cartilage Arthritis Rheum 33 1990 1695 1701
27. T. Sugiyama Involvement of interleukin-6 and prostaglandin E2 in periarticular osteoporosis of postmenopausal women with rheumatoid arthritis J Bone Miner Metab 19 2001 89 96
28. A. Verbruggen, L.S. De Clerck, C.H. Bridts, J.F. Van Offel, and W.J. Stevens Flow cytometrical determination of interleukin 1beta, interleukin 6 and tumour necrosis factor alpha in monocytes of rheumatoid arthritis patients; relation with parameters of osteoporosis Cytokine 11 1999 869 874
29. P. Peveri, A. Walz, B. Dewald, and M. Baggiolini A novel neutrophil-activating factor produced by human mononuclear phagocytes J Exp Med 167 1988 1547 1559
30. P.R. Elford, and P.H. Cooper Induction of neutrophil-mediated cartilage degradation by interleukin-8 Arthritis Rheum 34 1991 325 332
31. F.P. Cantatore, C.A. Acquista, and V. Pipitone Evaluation of bone turnover and osteoclastic cytokines in early rheumatoid arthritis treated with alendronate J Rheumatol 26 1999 2318 2323
32. F. Eggelmeijer, S.E. Papapoulos, H.C. van Paassen, B.A. Dijkmans, and F.C. Breedveld Clinical and biochemical response to single infusion of pamidronate in patients with active rheumatoid arthritis: a double blind placebo controlled study J Rheumatol 21 1994 2016 2020
33. J. Hasegawa, M. Nagashima, M. Yamamoto, T. Nishijima, S. Katsumata, and S. Yoshino Bone resorption and inflammatory inhibition efficacy of intermittent cyclical etidronate therapy in rheumatoid arthritis J Rheumatol 30 2003 474 479
34. P. Herrak, B. Gortz, S. Hayer, K. Redlich, E. Reiter, and J. Gasser Zoledronic acid protects against local and systemic bone loss in tumor necrosis factor-mediated arthritis Arthritis Rheum 50 2004 2327 2337
35. A. Matsuo, T. Shuto, G. Hirata, H. Satoh, Y. Matsumoto, and H. Zhao Antiinflammatory and chondroprotective effects of the aminobisphosphonate incadronate (YM175) in adjuvant induced arthritis J Rheumatol 30 2003 1280 1290
36. N.A. Sims, J.R. Green, M. Glatt, S. Schlict, T.J. Martin, and M.T. Gillespie Targeting osteoclasts with zoledronic acid prevents bone destruction in collagen-induced arthritis Arthritis Rheum 50 2004 2338 2346
37. J.F. Van Offel, A.J. Schuerwegh, C.H. Bridts, P.G. Bracke, W.J. Stevens, and L.S. De Clerck Influence of cyclic intravenous pamidronate on proinflammatory monocytic cytokine profiles and bone density in rheumatoid arthritis treated with low dose prednisolone and methotrexate Clin Exp Rheumatol 19 2001 13 20
38. A.J. Schuerwegh, E.J. Dombrecht, W.J. Stevens, J.F. Van Offel, C.H. Bridts, and L.S. De Clerck Influence of pro-inflammatory (IL-1 alpha, IL-6, TNF-alpha, IFN-gamma) and anti-inflammatory (IL-4) cytokines on chondrocyte function Osteoarthritis Cartilage 11 2003 681 687
39. E.J. Dombrecht, M.C. Nevitt, J.F. Van Offel, A.J. Schuerwegh, C.H. Bridts, and W.J. Stevens Effect of bisphosphonates and dexamethasone on nitric oxide production of cartilage Bone 34 2004 S53 [abstract]
40. C.I. Westacott, J.T. Whicher, I.C. Barnes, D. Thompson, A.J. Swan, and P.A. Dieppe Synovial fluid concentration of five different cytokines in rheumatic diseases Ann Rheum Dis 49 1990 676 681
41. J.F. Van Offel, A.J. Schuerwegh, C.H. Bridts, W.J. Stevens, and L.S. De Clerck Effect of bisphosphonates on viability, proliferation, and dexamethasone-induced apoptosis of articular chondrocytes Ann Rheum Dis 61 2002 925 928
42. F. Wingen, and D. Schmahl Pharmacokinetics of the osteotropic diphosphonate 3-amino-1-hydroxypropane-1,1-diphosphonic acid in mammals Arzneimittelforschung 37 1987 1037 1042
43. T. Usui, T. Watanabe, and S. Higuchi Pharmacokinetics of YM175, a new bisphosphonate, in rats and dogs Drug Metab Dispos 23 1995 1214 1219
44. D. Thiebaud, A. Sauty, P. Burckhardt, P. Leuenberger, L. Sitzler, and J.R. Green An in vitro and in vivo study of cytokines in the acute-phase response associated with bisphosphonates Calcif Tissue Int 61 1997 386 392
45. N.V. Podworny, R.A. Kandel, R.C. Renlund, and M.D. Grynpas Partial chondroprotective effect of zoledronate in a rabbit model of inflammatory arthritis J Rheumatol 26 1999 1972 1982
46. M.D. Francis, K. Hovancik, and R.W. Boyce NE-58095: a diphosphonate which prevents bone erosion and preserves joint architecture in experimental arthritis Int J Tissue React 11 1989 239 252
47. K. Redlich, S. Hayer, A. Maier, C.R. Dunstan, M. Tohidast-Akrad, and S. Lang Tumor necrosis factor alpha-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerin Arthritis Rheum 46 2002 785 792
48. M.W. Pysklywec, E.L. Moran, and E.R. Bogoch Zoledronate (CGP 42'446), a bisphosphonate, protects against metaphyseal intracortical defects in experimental inflammatory arthritis J Orthop Res 15 1997 858 861
49. H. Okamoto, M. Yamamura, Y. Morita, S. Harada, H. Makino, and Z. Ota The synovial expression and serum levels of interleukin-6, interleukin-11, leukemia inhibitory factor, and oncostatin M in rheumatoid arthritis Arthritis Rheum 40 1997 1096 1105
50. F.A. Houssiau, J.P. Devogelaer, J. Van Damme, C.N. de Deuxchaisnes, and J. Van Snick Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides Arthritis Rheum 31 1988 784 788
51. R. Horai, S. Saijo, H. Tanioka, S. Nakae, K. Sudo, and A. Okahara Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice J Exp Med 191 2000 313 320
52. J. Martel-Pelletier, D.J. Welsch, and J.P. Pelletier Metalloproteases and inhibitors in arthritic diseases Best Pract Res Clin Rheumatol 15 2001 805 829
53. F.F. Mohammed, D.S. Smookler, and R. Khokha Metalloproteinases, inflammation, and rheumatoid arthritis Ann Rheum Dis 62 Suppl. 2 2000 ii43 ii47
54. W.P. Maksymowych, T. Bedilion, H. Buenviaje, L. O'Brien, and A.S. Russel Intravenous pamidronate therapy suppresses markers of articular cartilage degradation/turnover in patients with ankylosing spondylitis Arthritis Rheum 46 2002 S432 [abstract]
55. Y.T. Konttinen, T. Salo, R. Hanemaaijer, H. Valleala, T. Sorsa, and M. Sutinen Collagenase-3 (MMP-13) and its activators in rheumatoid arthritis: localization in the pannus-hard tissue junction and inhibition by alendronate Matrix Biol 18 1999 401 412
56. J.L. Sanders, G. Tarjan, S.A. Foster, and P.H. Stern Alendronate/ interleukin-1beta cotreatment increases interleukin-6 in bone and UMR-106 cells: dose dependence and relationship to the antiresorptive effect of alendronate J Bone Miner Res 13 1998 786 792
57. S. Derenne, M. Amiot, S. Barille, M. Collette, N. Robillard, and P. Berthaud Zoledronate is a potent inhibitor of myeloma cell growth and secretion of IL-6 and MMP-1 by the tumoral environment J Bone Miner Res 14 1999 2048 2056
58. N. Giuliani, M. Pedrazzoni, G. Passeri, and G. Girasole Bisphosphonates inhibit IL-6 production by human osteoblast-like cells Scand J Rheumatol 27 1998 38 41
59. E. Engel, S. Serrano, M.L. Marinoso, J. Lloreta, F. Ulloa, and X. Nogues Alendronate and etidronate do not regulate interleukin 6 and 11 synthesis in normal human osteoblasts in culture Calcif Tissue Int 72 2003 228 235
60. J. Monkkonen, M. Taskinen, S.O. Auriola, and A. Urtti Growth inhibition of macrophage-like and other cell types by liposome-encapsulated, calcium-bound, and free bisphosphonates in vitro J Drug Target 2 1994 299 308
61. L.S. De Clerck, C.M. De Gendt, C.H. Bridts, N. Van Osselaer, and W.J. Stevens Expression of neutrophil activation markers and neutrophil adhesion to chondrocytes in rheumatoid arthritis patients: relationship with disease activity Res Immunol 146 1995 81 87
62. A.J. Schuerwegh, L.S. De Clerck, C.H. Bridts, and W.J. Stevens Comparison of intracellular cytokine production with extracellular cytokine levels using two flow cytometric techniques Cytometry 55B 2003 52 58
63. E.B. Cook, J.L. Stahl, L. Lowe, R. Chen, E. Morgan, and J. Wilson Simultaneous measurement of six cytokines in a single sample of human tears using microparticle-based flow cytometry: allergics vs. non-allergics J Immunol Methods 254 2001 109 118