Establishment of an in vitro model using NR8383 cells and mycobacterium bovis calmette-guérin that mimics a chronic infection of Mycobacterium tuberculosis

In Vivo

Volumn 19, Issue 5, 2005, Pages 821-830

  Hino, Mami ^a   Oda, Mutsumi ^a   Yoshida, Aya ^b   Nakata, Kazue ^a   Kohchi, Chie ^a,c   Nishizawa, Takashi ^a   Inagawa, Hiroyuki ^a,c,d   Hori, Hitoshi ^b   Makino, Kimiko ^c   Terada, Hiroshi ^c   Soma, Gen Ichiro ^a,c  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

^d NATIONAL FISHERIES UNIVERSITY   (Japan)

Author keywords

Alveolar macrophages; Intracellular pathogen; Phagocytosis; Tuberculosis

Indexed keywords

NITROGEN OXIDE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACILLUS; CELL CULTURE; CELL KILLING; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CHRONICITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXPERIMENTAL MODEL; IN VITRO STUDY; LUNG ALVEOLUS MACROPHAGE; MALE; MOUSE; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHAGOCYTOSIS; RAT; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

EID: 23044479236     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Russell DG: Mycobacterium tuberculosis: here today, and here tomorrow. Nat Rev Mol Cell Biol 2: 569-577, 2001.
2. Means TK, Wang S, Lien E, Yoshimura A, Golenbock DT and Fenton MJ: Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis. J Immunol 163: 3920-3927, 1999.
3. Underhill DM, Ozinsky A, Smith KD and Aderem A: Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages. Proc Natl Acad Sci USA 96: 14459-14463, 1999.
4. Thoma-Uszynski S, Stenger S, Takeuchi O, Ochoa MT, Engele M, Sieling PA, Barnes PF, Rollinghoff M, Bolcskei PL, Wagner M, Akira S, Norgard MV, Belisle JT, Godowski PJ, Bloom BR and Modlin RL: Induction of direct antimicrobial activity through mammalian toll-like receptors. Science 291: 1544-1547, 2001.
5. Abel B, Thieblemont N, Quesniaux VJ, Brown N, Mpagi J, Miyake K, Bihl F and Ryffel B: Toll-like receptor 4 expression is required to control chronic Mycobacterium tuberculosis infection in mice. J Immunol 169: 3155-3162, 2002.
6. Bekker LG, Freeman S, Murray PJ, Ryffel B and Kaplan G: TNF-alpha controls intracellular mycobacterial growth by both inducible nitric oxide synthase-dependent and inducible nitric oxide synthase-independent pathways. J Immunol 166: 6728-6734, 2001.
7. Zganiacz A, Santosuosso M, Wang J, Yang T, Chen L, Anzulovic M, Alexander S, Gicquel B, Wan Y, Bramson J, Inman M and Xing Z: TNF-alpha is a critical negative regulator of type 1 immune activation during intracellular bacterial infection. J Clin Invest 113: 401-413, 2004.
8. Wakeham J, Wang J, Magram J, Croitoru K, Harkness R, Dunn P, Zganiacz A and Xing Z: Lack of both types 1 and 2 cytokines, tissue inflammatory responses, and immune protection during pulmonary infection by Mycobacterium bovis bacille Calmette-Guerin in IL-12-deficient mice. J Immunol 160: 6101-6111, 1998.
9. Fortune SM, Solache A, Jaeger A, Hill PJ, Belisle JT, Bloom BR, Rubin EJ and Ernst JD: Mycobacterium tuberculosis inhibits macrophage responses to IFN-gamma through myeloid differentiation factor 88-dependent and -independent mechanisms. J Immunol 172: 6272-6280, 2004.
10. Malik ZA, Thompson CR, Hashimi S, Porter B, Iyer SS and Kusner DJ: Cutting edge: Mycobacterium tuberculosis blocks Ca2+ signaling and phagosome maturation in human macrophages via specific inhibition of sphingosine kinase. J Immunol 170: 2811-2815, 2003.
11. 2+/calmodulin-PI3K hVPS34 cascade. J Exp Med 198: 653-659, 2003.
12. Hernandez-Pando R, Orozco H and Mancilla R: T-cell lung granulomas induced by sepharose-coupled Mycobacterium tuberculosis protein antigens: immunosuppressive phenomena reversed with cyclophosphamide and indomethacin. Immunology 86: 506-511, 1995.
13. Brightbill HD, Libraty DH, Krutzik SR, Yang RB, Belisle JT, Bleharski JR, Maitland M, Norgard MV, Plevy SE, Smale ST, Brennan PJ, Bloom BR, Godowski PJ and Modlin RL: Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science 285: 732-736, 1999.
14. Beatty WL, Ullrich HJ and Russell DG: Mycobacterial surface moieties are released from infected macrophages by a constitutive exocytic event. Eur J Cell Biol 80: 31-40, 2001.
15. Nau GJ, Richmond JF, Schlesinger A, Jennings EG, Lander ES and Young RA: Human macrophage activation programs induced by bacterial pathogens. Proc Natl Acad Sci USA 99: 1503-1508, 2002.
16. Ciaramella A, Cavone A, Santucci MB, Amicosante M, Martino A, Auricchio G, Pucillo LP, Colizzi V and Fraziano M: Proinflammatory cytokines in the course of Mycobacterium tuberculosis-induced apoptosis in monocytes/macrophages. J Infect Dis 186: 1277-1282, 2002.
17. Stokes RW and Doxsee D: The receptor-mediated uptake, survival, replication, and drug sensitivity of Mycobacterium tuberculosis within the macrophage-like cell line THP-1: a comparison with human monocyte-derived macrophages. Cell Immunol 197: 1-9, 1999.
18. Hirsch CS, Ellner JJ, Russell DG and Rich EA: Complement receptor-mediated uptake and tumor necrosis factor-alpha-mediated growth inhibition of Mycobacterium tuberculosis by human alveolar macrophages. J Immunol 152: 743-753, 1994.
19. Baeuerle PA and Baltimore D: NF-kappa B: ten years after. Cell 87: 13-20, 1996.
20. Mukhopadhyay A, Suttles J, Stout RD and Aggarwal BB: Genetic deletion of the tumor necrosis factor receptor p60 or p80 abrogates ligand-mediated activation of nuclear factor-kappa B and of mitogen-activated protein kinases in macrophages. J Biol Chem 276: 31906-31912, 2001.
21. Surewicz K, Aung H, Kanost RA, Jones L, Hejal R and Toossi Z: The differential interaction of p38 MAP kinase and tumor necrosis factor-alpha in human alveolar macrophages and monocytes induced by Mycobacterium tuberculosis. Cell Immunol 228: 34-41, 2004.
22. Mehta PK, King CH, White EH, Murtagh JJ Jr and Quinn FD: Comparison of in vitro models for the study of Mycobacterium tuberculosis invasion and intracellular replication. Infect Immun 64: 2673-2679, 1996.
23. Helmke RJ, German VF and Mangos JA: A continuous alveolar macrophage cell line: comparisons with freshly derived alveolar macrophages. In Vitro Cell Dev Biol 25: 44-48, 1989.
24. Ruff MR and Gifford GE: Purification and physico-chemical characterization of rabbit tumor necrosis factor. J Immunol 125: 1671-1677, 1980.
25. Ding AH, Nathan CF and Stuehr DJ: Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J Immunol 141: 2407-2412, 1988.
26. Granger DL, Taintor RR, Boockvar KS and Hibbs JB Jr.: Measurement of nitrate and nitrite in biological samples using nitrate reductase and Griess reaction. Methods Enzymol 268: 142-151, 1996.
27. Hopper KE, Wood PR and Nelson DS: Macrophage heterogeneity. Vox Sang 36: 257-274, 1979.
28. Smith PD, Smythies LE, Mosteller-Barnum M, Sibley DA, Russell MW, Merger M, Sellers MT, Orenstein JM, Shimada T, Graham MF and Kubagawa H: Intestinal macrophages lack CD14 and CD89 and consequently are down-regulated for LPS- and IgA-mediated activities. J Immunol 167: 2651-2656, 2001.
29. Xaus J, Comalada M, Valledor AF, Lloberas J, Lopez-Soriano F, Argiles JM, Bogdan C and Celada A: LPS induces apoptosis in macrophages mostly through the autocrine production of TNF-alpha. Blood 95: 3823-3831, 2000.
30. Wang MJ, Jeng KC and Shih PC: Differential expression of inducible nitric oxide synthase gene by alveolar and peritoneal macrophages in lipopolysaccharide-hyporesponsive C3H/HeJ mice. Immunology 98: 497-503, 1999.
31. Ogle CK, Wu JZ, Mao X, Szczur K, Alexander JW and Ogle JD: Heterogeneity of Kupffer cells and splenic, alveolar, and peritoneal macrophages for the production of TNF, IL-1, and IL-6. Inflammation 18: 511-523, 1994.
32. Choi HS, Rai PR, Chu HW, Cool C and Chan ED: Analysis of nitric oxide synthase and nitrotyrosine expression in human pulmonary tuberculosis. Am J Respir Crit Care Med 166: 178-186, 2002.
33. Helmke RJ, Boyd RL, German VF and Mangos JA: From growth factor dependence to growth factor responsiveness: the genesis of an alveolar macrophage cell line. In Vitro Cell Dev Biol 23: 567-574, 1987.
34. Tschaikowsky K: Protein kinase C inhibitors suppress LPS-induced TNF production in alveolar macrophages and in whole blood: the role of encapsulation into liposomes. Biochim Biophys Acta 1222: 113-121, 1994.
35. Mosley K and Cuzner ML: Receptor-mediated phagocytosis of myelin by macrophages and microglia: effect of opsonization and receptor blocking agents. Neurochem Res 21: 481-487, 1996.
36. van der Laan LJ, Ruuls SR, Weber KS, Lodder IJ, Dopp EA and Dijkstra CD: Macrophage phagocytosis of myelin in vitro determined by flow cytometry: phagocytosis is mediated by CR3 and induces production of tumor necrosis factor-alpha and nitric oxide. J Neuroimmunol 70: 145-152, 1996.
37. Crowle AJ, Dahl R, Ross E and May MH: Evidence that vesicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic. Infect Immun 59: 1823-1831, 1991.
38. Vignal C, Guerardel Y, Kremer L, Masson M, Legrand D, Mazurier J and Elass E: Lipomannans, but not lipoarabinomannans, purified from Mycobacterium chelonae and Mycobacterium kansasii induce TNF-alpha and IL-8 secretion by a CD14-toll-like receptor 2-dependent mechanism. J Immunol 171: 2014-2023, 2003.
39. Walburger A, Koul A, Ferrari G, Nguyen L, Prescianotto-Baschong C, Huygen K, Klebl B, Thompson, C, Bacher G and Pieters J: Protein kinase G from pathogenic mycobacteria promotes survival within macrophages. Science 304: 1800-1804, 2004.
40. Vidal SM, Malo D, Vogan K, Skamene E and Gros P: Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg. Cell 73: 469-485, 1993.
41. Tapper H and Sundler R: Protein kinase C and intracellular pH regulate zymosan-induced lysosomal enzyme secretion in macrophages. J Leukoc Biol 58: 485-494, 1995.
42. Xu S, Cooper A, Sturgill-Koszycki S, van Heyningen T, Chatterjee D, Orme I, Allen P and Russell DG: Intracellular trafficking in Mycobacterium tuberculosis and Mycobacterium avium-infected macrophages. J Immunol 153: 2568-2578, 1994.
43. Fratti RA, Backer JM, Gruenberg J, Corvera S and Deretic V: Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest. J Cell Biol 154: 631-644, 2001.
44. Engele M, Stossel E, Castiglione K, Schwerdtner N, Wagner M, Bolcskei P, Rollinghoff M and Stenger S: Induction of TNF in human alveolar macrophages as a potential evasion mechanism of virulent Mycobacterium tuberculosis. J Immunol 168: 1328-1337, 2002.