Expression of functional chemokine receptors by rat cerebellar neurons

Journal of Neuroimmunology

Volumn 124, Issue 1-2, 2002, Pages 16-28

  Gillard, Samantha E ^a   Lu, Meiling ^b   Mastracci, Rose M ^c   Miller, Richard J ^b  

^a ELI LILLY AND COMPANY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

Calcium mobilization; Cerebellar neurons; Chemokines; Signal transduction; Viralkines

Indexed keywords

CALCIUM ION; CHEMOKINE; CHEMOKINE RECEPTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PERTUSSIS TOXIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CALCIUM TRANSPORT; CELL CULTURE; CELL ISOLATION; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CONTROLLED STUDY; ENZYME ACTIVATION; GRANULE CELL; IMAGING; IMMUNE SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PURKINJE CELL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; BIOLOGICAL TRANSPORT; CALCIUM; CELL AGING; CELLS, CULTURED; CEREBELLUM; CHEMOKINES; CHEMOKINES, CC; ELECTROPHYSIOLOGY; IMMUNOHISTOCHEMISTRY; MACROPHAGE INFLAMMATORY PROTEINS; NEURONS; PERTUSSIS TOXIN; PURKINJE CELLS; RATS; RATS, INBRED STRAINS; RECEPTORS, CHEMOKINE; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; VIRAL PROTEINS; VIRULENCE FACTORS, BORDETELLA;

EID: 0036198825     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(02)00005-X     Document Type: Article

References (44)

1. MIP-3α, MIP-3β and fractalkine induce the locomotion and the mobilization of intracellular calcium, and activate the heterotrimeric G proteins in human natural killer cells
2. HIV-1 coreceptor activity of CCR5 and its inhibition by chemokines: Independence from G protein signaling and importance of coreceptor downmodulation
3. HIV coreceptor downregulation as antiviral principle: SDF-1α-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication
4. Molecular mechanism of desensitization of the chemokine receptor CCR-5: Receptor signaling and internalization are dissociable from its role as an HIV-1 co-receptor
5. Trophic effects of interleukin-4,-7 and -8 on hippocampal neuronal cultures: Potential involvement of glial derived factors
6. Chemokines and leukocyte traffic
7. Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines
8. Human chemokines: An update
9. CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1α and IP-10 are expressed in demyelinating brain lesions
10. Expression of pro-inflammatory cytokine and chemokine mRNA upon experimental spinal cord injury in mouse: An in situ hybridization study
11. Cultured rat microglia express functional β-chemokine receptors
12. The properties of intracellular calcium stores in cultured rat cerebellar neurons
13. i protein: Seven transmembrane coreceptors for human immunodeficiency virus into cells
14. Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(α), MIP-1(β) and RANTES
15. Identification of pore-forming subunit of P-type calcium channels: An antisense study on rat cerebellar Purkinje cells in culture
16. Chemokines increase intracellular calcium and activate cyclic AMP response element-binding protein from the rat area postrema and nucleus of the solitary tract
17. CXC chemokines interleukin-8 (IL-8) and growth-related gene product alpha (GROα) modulate Purkinje neuron activity in mouse cerebellum
18. Synchronous synthesis of the α- and β-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encaphalomyelitis
19. Differential and time-dependent expression of monocyte chemoattractant protein-1 mRNA by astrocytes and macrophages in rat brain: Effects of ischemia and peripheral lipopolysaccharide administration
20. Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia
21. Expression of chemokine receptors by subsets of neurons in the central nervous system
22. 2+ channels
23. Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis
24. Selective G protein coupling by C-C chemokine receptors
25. CXCR-4 (Fusin), a co-receptor for the type 1 human immunodeficiency virus (HIV-1), is expressed in the human brain in a variety of cell types, including microglia and neurons
26. The chemokine growth-related gene product β protects rat cerebellar granule cells from apoptotic cell death through α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors
27. SDF-1α mediated modulation of synaptic transmission in rat cerebellum
28. Characterization of fractalkine in rat brain cells: Migratory and activation signals for CX3CR-1-expressing microglia
29. Role of the heterotrimeric G proteins in stromal-derived factor-1α-induced natural killer cell chemotaxis and calcium mobilization
30. Intracellular signalling pathways induced by chemokines in natural killer cells
31. Chemokines and chemokine receptors in the CNS: A possible role in neuroinflammation and patterning
32. Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity
33. Expression of CX3CR1 chemokine receptors on neurons and their role in neuronal survival
34. AIDS and the brain: Is there a chemokine connection?
35. 2+ channels in central neurons
36. s
37. Modulation of the neurotransmitter release in rat cerebellar neurons by GROβ
38. Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: Implications for recruitment of leukocytes into brain and lymph nodes
39. 2+ channels by PTX-sensitive G-proteins is blocked by N-ethylmaleimide in rat sympathetic neurons
40. Cloning of rat HIV-1 chemokine coreceptor CKR5 from microglia and upregulation of its mRNA in ischemic and endotoxinemic rat brain
41. Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease
42. Chemokine receptor CCR5 functionally couples to inhibitory G proteins and undergoes desensitization
43. Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1 associated dementia
44. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development